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Zahida Khan, MD, Pediatric Gastroenterology, Milwaukee, WI, Children's Wisconsin

ZahidaKhanMDPhD

Pediatric Gastroenterology • Milwaukee, WI

Pediatric Hepatology and Liver Transplantation

Pediatric Hepatologist

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  • Office

    Children’s Hospital of Wisconsin, Medical College of Wisconsin
    8701 Watertown Plank Rd, Pediatric Gastroenterology B610
    Milwaukee, WI 53226
    Phone+1 414-266-3690
    Fax+1 414-266-3676
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Summary

  • My long-term career objective is to acquire the necessary training, practical experience, and knowledge to become a leading independent principal investigator in studying the basic cell biology to correct molecular defects in pediatric liver-based metabolic diseases. My current project investigates the role of liver progenitor cells in response to diseased hepatocytes in alpha-1 antitrypsin deficiency. These findings may have potential clinical applications in cellular therapy. My combined MD/PhD training has given me the skills to plan, implement, and analyze data in liver pathobiology, with a focus on cellular approaches to tissue engineering and liver regeneration. My clinical training has given me a strong foundation in pediatric hepatology. My GI fellowship has given me the opportunity to extend my research into the pathophysiology of A1AT deficiency. I am currently an Attending Physician at Children's Hospital of Pittsburgh, appointed as an Assistant Professor in Pediatric Gastroenterology and Pathology. This position will enable me to develop the clinical and research expertise needed to become an independent physician-scientist in pediatric liver diseases, with specialization in transplant hepatology.

Education & Training

  • Baylor College of Medicine/Texas Children's Hospital
    Baylor College of Medicine/Texas Children's HospitalFellowship, Advanced Pediatric Transplant Hepatology, 2016 - 2017
  • UPMC Medical Education
    UPMC Medical EducationFellowship, Pediatric Gastroenterology, 2012 - 2015
  • Cincinnati Children's Hospital Medical Center
    Cincinnati Children's Hospital Medical CenterResidency, Pediatrics, 2008 - 2011
  • University of Pittsburgh School of Medicine
    University of Pittsburgh School of MedicineClass of 2008
  • University of Pittsburgh School of Medicine, Medical Scientist Training Program
    University of Pittsburgh School of Medicine, Medical Scientist Training ProgramPh.D., Cellular and Molecular Pathology, Cellular Approaches to Tissue Engineering and Regeneration, 2002 - 2006
  • Simmons College
    Simmons CollegeB.S., Biochemistry, Magna Cum Laude, 1994 - 1998

Certifications & Licensure

  • WI State Medical License
    WI State Medical License 2019 - 2025
  • OH State Medical License
    OH State Medical License 2008 - 2024
  • PA State Medical License
    PA State Medical License 2011 - 2021
  • American Board of Pediatrics Pediatrics
  • American Board of Pediatrics Pediatric Gastroenterology
  • American Board of Pediatrics Pediatric Transplant Hepatology

Awards, Honors, & Recognition

  • Annual Scientific Meeting Second Prize, Best Poster Presentation Pennsylvania Society of Gastroenterology (PSG), 2014
  • Fellows-in-Training Travel Award Pennsylvania Society for Gastroenterology (PSG), 2014
  • Travel Award, selected as a Best Abstract for Oral Presentation Studies in Pediatric Liver Transplantation (SPLIT), 2014
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Publications & Presentations

PubMed

Journal Articles

  • Pathogenesis of alpha-1 antitrypsin deficiency in the liver: New approaches to old questions.  
    Khan Z, Journal of Liver Research, Disorders and Therapy, 5/17/2016
  • Prediction of early-and late-growth morphologies of ionic crystals  
    Soltzberg LJ, Carneiro O, Joseph GS, Khan Z, Meretsky TD, Ng MM, Ofek SA, Acta Cryst, 1/1/1998

Books/Book Chapters

  • Translational Gastroenterology: Organogenesis to Disease 
    Chapter: Congenital and acquired diseases of the liver 
    Page 165.0 - 178.0Khan Z, Tafaleng EN, Soltys KA, Fox IJEditors: D.L. Gumucio, L.C. Samuelson, J.R. Spence.John Wiley & Sons, West Sussex, UKEdition 1st,2014
  • Textbook of Hepatology: from Basic Science to Clinical Practice 
    Chapter: Ultrastructure of the hepatocyte 
    Page 20.0 - 28.0Khan Z, Stolz DB, Crawford JMEditors: Blackwell. J.P. Benhamou, A. Blei, J-F Dufour, P. Gines, S. Friedmann, J. Reichen, J. Rodes, C. Valla, F. Zoulim.Oxford University Press, New YorkEdition 3rd,2007
  • Amyloid and Amyloidosis 1998 
    Chapter: Biophysical studies of amyloidogenic and non-amyloidogenic immunoglobulin kappa I light chains 
    Page 193.0 - 195.0Khan Z, Skinner M, Connors LH, Walsh MTEditors: R. Kyle and M. Gertz.Parthenon Press, New York

Abstracts/Posters

  • Immunohistochemical analysis of LGR5 expression in pediatric liver disease
    Khan Z, Orr A, Michalopoulos GK, Ranganathan S, FASEB J, 1/1/2015
  • Phenotypic differences of PAS+ globule-containing and globule-devoid hepatocytes in a PiZ mouse model of alpha-1 antitrypsin deficiency
    Khan Z, Stolz DB, Perlmutter DH, Michalopoulos GK, J. Pediatr. Gastroenterol. Nutr, 1/1/2014
  • Expression and localization of HIF prolyl 4-hydroxylases in rat hepatocytes and JM1 tumor cells
    Khan Z, Stolz DB, Bowen WC, Michalopoulos GK, FASEB J, 1/1/2006
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Grant Support

  • Age-dependent effects of intracellular protein aggregation on hepatocyte proliferation in alpha-1 antitrypsin deficiencyPittsburgh Liver Research Center2017–2018
  • Advanced single cell analysis of proliferation in PiZ mouse hepatocytesAlpha-1 Foundation2016–2017
  • Transplantation of liver progenitor cells to promote ATZ globule clearance in A1AT deficiencyHillman Foundation2016
  • “Hepatocyte repopulation by liver progenitor cells in A1AT deficiency” Pilot & Feasibility GrantAlpha-1 Foundation2015–2016
  • "Molecular Basis of Pediatric Disease", Child Health Research Center Development AwardNational Institute of Child Health and Human Development2015–2016
  • Basic/Translational Research Training for CHP Pediatric FellowsNIH T322013–2015
  • Cellular Approaches to Tissue Engineering and Regeneration (CATER)National Institute of Biomedical Imaging and Bioengineering T322003–2005
  • Medical Scientist Training Program (MSTP)NIH T322000–2002

Committees

  • Hepatology Committee, NASPGHAN 2016 - Present
  • Research Awards Committee, AASLD 2016 - Present
  • Research Committee, NASPGHAN 2013 - 2016

Professional Memberships

Hospital Affiliations

External Links

Dr. Zahida Khan, Dr. Zahida Khan, MD, Dr. Z Khan