TimothyN.ShowalterMDMPH

Radiation Oncology • Charlottesville, VA

Gynecologic Cancer, Sarcoma, Urologic Cancer

Professor, Radiation Oncology, University of Virginia

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Office
1215 Hospital Dr
Charlottesville, VA 22908
Phone+1 434-924-0211

Fax+1 434-982-3759
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Summary

I am a board-certified radiation oncologist who focuses on using advanced radiation therapy techniques, including brachytherapy, to provide precision radiation treatment for prostate cancer, other genitourinary cancers, and gynecological cancers. I am passionate about advocating for patient access to high-quality brachytherapy. I am committed to research aimed at improving patient care.

Education & Training

Sidney Kimmel Medical College at Thomas Jefferson University/TJUHResidency, Radiation Oncology, 2005 - 2009
Presbyterian Medical Center of the University of Pennsylvania Health SystemInternship, Transitional Year, 2004 - 2005
University of Virginia School of MedicineClass of 2004

Certifications & Licensure

VA State Medical License 2012 - 2024
PA State Medical License 2004 - 2012
American Board of Radiology Radiation Oncology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013

Clinical Trials

Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer Start of enrollment: 2009 Sep 01
Active, not recruiting
Phase 3
Stereotactic Body Radiation Therapy in Treating Patients With Low- and Intermediate-Risk Prostate Cancer Start of enrollment: 2013 Mar 08
Terminated
Not Applicable
Shorter Duration Radiotherapy to Treat Prostate Cancer After Removal of the Prostate Start of enrollment: 2013 Apr 01
Completed
Phase 1, Phase 2
IORT (Intra-operative Radiation Therapy) in Early Stage Breast Cancer Start of enrollment: 2013 Dec 01
Completed
Not Applicable
Cardiovascular Risk and Preventive Care in Prostate Cancer Patients Receiving Radiation and Hormone Therapy Start of enrollment: 2012 Jun 01
Completed
Phase 1/2 Study to Determine Optimal Dose for Treating Bone Metastases Using Novel STAT-RT Workflow Start of enrollment: 2013 Oct 01
Unknown status
Not Applicable
EBRT and HDR Brachytherapy for Unfavorable-intermediate, High, and Very High-risk Prostate Cancer Start of enrollment: 2020 Jul 30
Recruiting
Phase 2
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Publications & Presentations

PubMed

A randomized trial evaluating a novel hydrogel packing system compared to standard packing during image-guided high-dose rate brachytherapy boost for cervical cancer.
Gina Petroni, Kristi Ward, Wendy Zheng, Matthew Mistro, Bruce Libby, Kara D Romano, Christopher McLaughlin, Timothy N Showalter, Einsley M Janowski> ;Brachytherapy. 2024 Mar 21
Novel Form of Breast Intraoperative Radiation Therapy with CT-Guided High-Dose-Rate Brachytherapy: Interim Results of a Prospective Phase-II Clinical Trial.
Lena M Turkheimer, Gina R Petroni, Anneke T Schroen, David R Brenin, Melissa Lazar, Bruce Libby, Einsley M Janowski, Timothy N Showalter, Shayna L Showalter, Berger, A.> ;Journal of the American College of Surgeons. 2024 Jan 1
F-SHARP: a Phase I/II trial of focal salvage high-dose-rate brachytherapy for Radiorecurrent prostate cancer.
Abhishek A Solanki, Ryan K Yoo, William Adams, Elai Davicioni, Michael L Mysz, Steven Shea, Gopal N Gupta, Timothy Showalter, Aurelie Garant, Courtney Hentz, Ahmer Far...> ;BJU International. 2024 Feb 1
2 citations
Salvage prostate brachytherapy in radiorecurrent prostate cancer: An international Delphi consensus study.
Mark T Corkum, Mark K Buyyounouski, Albert J Chang, Hans T Chung, Peter Chung, Brett W Cox, Juanita M Crook, Brian J Davis, Steven J Frank, Ivan Henriquez, Eric M Horw...> ;Radiotherapy and Oncology. 2023 Jul 1
Long-Term Adherence to Adjuvant Endocrine Therapy Following Various Radiotherapy Modalities in Early Stage Hormone Receptor Positive Breast Cancer.
Kristin A Ward, Donald A Muller, Sunil W Dutta, Jason C Sanders, Christopher K Luminais, Trish A Millard, Timothy N Showalter, Shayna L Showalter, Einsley-Marie Janows...> ;Clinical Breast Cancer. 2023 Jun 1
Factors Associated With Cosmetic Outcomes After Treatment With a Novel Form of Breast Intraoperative Radiation Therapy.
Gabriella C Squeo, Max O Meneveau, Nikole E Varhegyi, Courtney M Lattimore, Einsley Janowski, Timothy N Showalter, Shayna L Showalter> ;The Journal of Surgical Research. 2023 Mar 1
Evaluating the relationship between vaginal apex "dog ears" and patterns of recurrence in endometrial cancer following adjuvant image guided vaginal cuff brachytherapy.
Emily K Venner, Kristin A Ward, Nolan A Wages, Bryant Walker, Bruce P Libby, Timothy N Showalter, Kara D Romano> ;Brachytherapy. 2022 Nov 19
1 citations
Dose differentiated high-dose-rate prostate brachytherapy: a feasibility assessment of MRI-guided dose escalation to dominant intra-prostatic lesions.
Christopher K Luminais, Hamidreza Nourzadeh, Eric Aliotta, Kristin Ward, David Cousins, Timothy N Showalter, Bruce Libby> ;Journal of Contemporary Brachytherapy. 2022 Oct 1
10 citations
Partial breast irradiation: An updated consensus statement from the American brachytherapy society.
Bethany Anderson, Douglas Arthur, Jean-Michel Hannoun-Levi, Mitchell Kamrava, Atif Khan, Robert Kuske, Daniel Scanderbeg, Chirag Shah, Simona Shaitelman, Timothy Showa...> ;Brachytherapy. 2022 Sep 15
Demystifying radiation oncology clinical trial concerns for protocol scientific review and institutional review board committee members.
Kristi A DeHaai, Benjamin M Hawkins, Kara D Romano, Nicholas G Zaorsky, Ronald C Chen, Timothy N Showalter, Qazi, J.> ;Contemporary Clinical Trials Communications. 2022 Jun 1
1 citations
Endoscopic assessment of radiological stage IVA cervical cancer: A bivariate meta-analysis supporting an evidence-based staging algorithm proposal.
Lucas G Sapienza, Justin J Thomas, Timothy N Showalter, Alfredo E Echeverria, Michelle S Ludwig, Albert C Chen, Eunji Jo, Vinícius F Calsavara, Susan G Hilsenbeck, Anu...> ;Gynecologic Oncology. 2022 Jun 1
4 citations
An Expert Review on the Combination of Relugolix With Definitive Radiation Therapy for Prostate Cancer.
Soumyajit Roy, Nicholas G Zaorsky, Hilary P Bagshaw, Alejandro Berlin, Alison Tree, Sandra Turner, Bridget Koontz, Paul Nguyen, Ronald Chen, Robert T Dess, William C J...> ;International Journal of Radiation Oncology, Biology, Physics. 2022 Jun 1
1 citations
ACR-ABS-ASTRO Practice Parameter for Transperineal Permanent Brachytherapy of Prostate Cancer.
Nathan H J Bittner, Brett W Cox, Brian Davis, Martin King, Colleen A F Lawton, Gregory S Merrick, Peter Orio, Zoubir Ouhib, Peter Rossi, Timothy Showalter, William Sma...> ;American Journal of Clinical Oncology. 2022 Jun 1
2 citations
A comparative study using time-driven activity-based costing in single-fraction breast high-dose rate brachytherapy: An integrated brachytherapy suite vs. decentralize...
Gabriella C Squeo, Courtney M Lattimore, Nicole L Simone, Greg Suralik, Sunil W Dutta, Michael D Schad, Lucy Su, Bruce Libby, Einsley-Marie Janowski, Shayna L Showalte...> ;Brachytherapy. 2022 Feb 4
Effects of a novel form of intraoperative radiation therapy on quality of life among patients with early-stage breast cancer.
Courtney M Lattimore, Max O Meneveau, Gina R Petroni, Nikole E Varhegyi, Gabriella C Squeo, Timothy N Showalter, Shayna L Showalter> ;Brachytherapy. 2022 Feb 2
23 citations
Low dose rate brachytherapy for primary treatment of localized prostate cancer: A systemic review and executive summary of an evidence-based consensus statement.
Martin T. King, Mira Keyes, Steven J. Frank, Juanita Crook, Wayne M. Butler, Peter J. Rossi, Brett Cox, Timothy N. Showalter, Firas Mourtada, Louis Potters, Richard G....> ;Brachytherapy. 2021 Sep 9
1 citations
Local control of 1–5 fraction radiotherapy regimens for spinal metastases: an analysis of the impacts of biologically effective dose and primary histology
Roman O. Kowalchuk, David Cousins, Kelly Spencer, K Martin Richardson, James M. Larner, Timothy N. Showalter, William H McAllister, Jason P. Sheehan, C. Ronald Kersh, ...> ;Reports of Practical Oncology and Radiotherapy. 2021 Aug 17
2 citations
A primer on time-driven activity-based costing in brachytherapy
Ria Mulherkar, Andrew Keller, Timothy N. Showalter, Nikhil G. Thaker, Sushil Beriwal> ;Brachytherapy. 2021 Aug 7
In Regard to Shah and Royce.
Einsley M. Janowski, Kara D. Romano, Timothy N. Showalter> ;International Journal of Radiation Oncology, Biology, Physics. 2021 Aug 1
14 citations
Pan-cancer analysis of prognostic metastatic phenotypes.
Nicholas G. Zaorsky, Xi Wang, Sara M Garrett, Eric J. Lehrer, Christine Lin, David J. DeGraff, Daniel E. Spratt, Daniel M. Trifiletti, Amar U. Kishan, Timothy N. Showa...> ;International Journal of Cancer. 2022 Jan 1
3 citations
Protons versus photons for the treatment of chordoma
Iman El Sayed, Daniel M. Trifiletti, Eric J. Lehrer, Timothy N. Showalter, Sunil W. Dutta> ;The Cochrane Database of Systematic Reviews. 2021 Jul 1
5 citations
Para-Aortic Nodal Radiation in the Definitive Management of Node-Positive Cervical Cancer.
Jason C. Sanders, Donald A. Muller, Sunil W. Dutta, Taylor J Corriher, Kari L. Ring, Timothy N. Showalter, Kara D. Romano> ;Frontiers in Oncology. 2021 Apr 29
7 citations
Hypofractionated Postprostatectomy Radiation Therapy for Prostate Cancer to Reduce Toxicity and Improve Patient Convenience: A Phase 1/2 Trial.
Nolan A. Wages, Jason C. Sanders, Amy B. Smith, Songserea Wood, Mitchell S. Anscher, Nikole Varhegyi, Tracey L. Krupski, Timothy Harris, Timothy N. Showalter> ;International Journal of Radiation Oncology, Biology, Physics. 2021 Apr 1
31 citations
Results of an early safety analysis of a study of the combination of pembrolizumab and pelvic chemoradiation in locally advanced cervical cancer.
Linda R. Duska, Jennifer Scalici, Sarah M. Temkin, Julie K. Schwarz, Erin K. Crane, Katherine M. Moxley, Chad A. Hamilton, Stephanie L. Wethington, Gina R. Petroni, Ni...> ;Cancer. 2020 Nov 15
8 citations
STAT RAD: Prospective Dose Escalation Clinical Trial of Single Fraction Scan-Plan-QA-Treat Stereotactic Body Radiation Therapy for Painful Osseous Metastases
Donald A. Muller, Nolan A. Wages, David D. Wilson, Sunil W. Dutta, Clayton E. Alonso, L. Handsfield, Quan Chen, Amy B. Smith, Kara D. Romano, Einsley M. Janowski, Timo...> ;Practical Radiation Oncology. 2020 Nov 1
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Journal Articles

Utility of CT Imaging in a Novel Form of High‐Dose‐Rate Intraoperative Breast Radiation Therapy
Shayna L Showalter, Adam C Berger, Taryn E Hassinger, Timothy N Showalter, David R Brenin, Journal of Medical Imaging and Radiation Oncology
Evaluation of Outcomes After Stereotactic Radiosurgery for Pilocytic Astrocytoma
Daniel M Trifiletti, Zhiyuan Xu, Timothy N Showalter, Journal of Neuro-Oncology

Press Mentions

ACR 2021 in BriefMay 24th, 2021
Couple Share $1.8 Million to Test More Precise Image-Guided Breast Radiation TherapyDecember 14th, 2018
NIH Awards $1.8M to Husband-and-Wife Duo to Evaluate Advanced Breast Radiation Therapy TechniqueNovember 16th, 2018
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