AamirMirMD

PubMed

• A Fluorescent Reporter Mouse forAssessment of Genome Editing with Diverse Cas Nucleases and Prime Editors.
  Chen, Z., Kwan, S., Shin, M., Liang, S., Chan, I., Kelly, K., Ghanta, K., Gaston, N., Cao, Y., Xie, J., Gao, G., Xue, W., Sontheimer, E., Watts, J., Mir, A., Hazeltine...> ;The CRISPR Journal. 2023 Dec 1
• 10 citations
  Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors.
  Sukanya Iyer, Aamir Mir, Joel Vega-Badillo, Benjamin P Roscoe, Raed Ibraheim, Lihua Julie Zhu, Jooyoung Lee, Pengpeng Liu, Kevin Luk, Esther Mintzer, Dongsheng Guo, Jo...> ;The CRISPR Journal. 2022 Oct 1
• 39 citations
  Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo.
  Raed Ibraheim, Phillip W. L. Tai, Aamir Mir, Nida Javeed, Jiaming Wang, Tomás Rodríguez, Suk Namkung, Samantha J. Nelson, Eraj Khokhar, Esther Mintzer, Stacy Maitland,...> ;Nature Communications. 2021 Nov 1
• 14 citations
  5′-Modifications improve potency and efficacy of DNA donors for precision genome editing
  Krishna S. Ghanta, Zexiang Chen, Aamir Mir, Gregoriy A Dokshin, Pranathi Meda Krishnamurthy, Yeonsoo Yoon, Judith Gallant, Ping Xu, Xiao-Ou Zhang, Ahmet R. Ozturk, Mas...> ;Elife. 2021 Oct 19
• 129 citations
  Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice.
  Pengpeng Liu, Shun-Qing Liang, Chunwei Zheng, Esther Mintzer, Yan G. Zhao, Karthikeyan Ponnienselvan, Aamir Mir, Erik J. Sontheimer, Guangping Gao, Terence R. Flotte, ...> ;Nature Communications. 2021 Apr 9
• 28 citations
  Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing
  Bianca Garcia, Jooyoung Lee, Alireza Edraki, Yurima Hidalgo-Reyes, Steven Erwood, Aamir Mir, Chantel N. Trost, Uri Seroussi, Sabrina Y. Stanley, Ronald D. Cohn, Julie ...> ;Cell Reports. 2019 Nov 12
• 152 citations
  A compact, high-accuracy Cas9 with a dinucleotide PAM for in vivo genome editing
  Alireza Edraki, Aamir Mir, Raed Ibraheim, Ildar Gainetdinov, Yeonsoo Yoon, Chun-Qing Song, Yueying Cao, Judith Gallant, Wen Xue, Jaime A. Rivera-Pérez, Erik J. Sontheimer> ;Molecular Cell. 2019 Feb 21
• 70 citations
  NmeCas9 is an intrinsically high-fidelity genome-editing platform
  Nadia Amrani, Xin D. Gao, Pengpeng Liu, Alireza Edraki, Aamir Mir, Raed Ibraheim, Ankit Gupta, Kanae E. Sasaki, Tong Wu, Paul Daniel Donohoue, Alexander H. Settle, Ale...> ;Genome Biology. 2018 Dec 5
• 57 citations
  Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins.
  Jooyoung Lee, Aamir Mir, Alireza Edraki, Bianca Garcia, Nadia Amrani, Hannah E. Lou, Ildar Gainetdinov, April Pawluk, Raed Ibraheim, Xin D. Gao, Pengpeng Liu, Alan R. ...> ;Mbio. 2018 Dec 4
• 69 citations
  All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo.
  Raed Ibraheim, Chun-Qing Song, Aamir Mir, Nadia Amrani, Wen Xue, Erik J. Sontheimer> ;Genome Biology. 2018 Sep 19
• 62 citations
  Heavily and Fully Modified RNAs Guide Efficient SpyCas9-mediated Genome Editing
  Aamir Mir, Julia F. Alterman, Matthew R. Hassler, Alexandre J. Debacker, Edward Hudgens, Dimas Echeverria, Michael H. Brodsky, Anastasia Khvorova, Jonathan K. Watts, E...> ;Nature Communications. 2018 Jul 6
• 73 citations
  C-BERST: defining subnuclear proteomic landscapes at genomic elements with dCas9–APEX2
  Xin D. Gao, Li-Chun Tu, Aamir Mir, Tomás Rodríguez, Yue-He Ding, John D. Leszyk, Job Dekker, Scott A. Shaffer, Lihua Julie Zhu, Scot A. Wolfe, Erik J. Sontheimer> ;Nature Methods. 2018 May 7
• 65 citations
  Type II-C CRISPR-Cas9 Biology, Mechanism, and Application
  Aamir Mir, Alireza Edraki, Jooyoung Lee, Erik J. Sontheimer> ;ACS Chemical Biology. 2018 Feb 16
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