AbdulKhokharMD

PubMed

• 9 citations
  Recruitment of trimeric proliferating cell nuclear antigen by G1-phase cyclin-dependent kinases following DNA damage with platinum-based antitumour agents
  Guanghan He, Jian Kuang, John M. Koomen, Ryuji Kobayashi, Abdul R. Khokhar, Zahid H. Siddik> ;British Journal of Cancer. 2013 Oct 29
• 40 citations
  The impact of S- and G2-checkpoint response on the fidelity of G1-arrest by cisplatin and its comparison to a non-cross-resistant platinum(IV) analog
  Guangan He, Jian Kuang, Abdul R. Khokhar, Zahid H. Siddik> ;Gynecologic Oncology. 2011 Aug 1
• 39 citations
  Upregulation of p27 and its inhibition of CDK2/cyclin E activity following DNA damage by a novel platinum agent are dependent on the expression of p21
  Guanghan He, Jian Kuang, Zaifeng Huang, John M. Koomen, Ryuji Kobayashi, Abdul R. Khokhar, Zahid H. Siddik> ;British Journal of Cancer. 2006 Dec 4
• 51 citations
  Phase II Study of a Liposome-Entrapped Cisplatin Analog (L-NDDP) Administered Intrapleurally and Pathologic Response Rates in Patients With Malignant Pleural Mesothelioma
  Charles Lu, Roman Perez-Soler, Bilal Piperdi, Garrett L. Walsh, Stephen G. Swisher, W. Roy Smythe, Hyung J. Shin, Jae Y. Ro, Lei Feng, Mylene T. Truong, Adiseshu Yalam...> ;Journal of Clinical Oncology. 2005 May 20
• Induction of p21 by p53 following DNA damage inhibits both Cdk4 and Cdk2 activities.
  He, G., Siddik, Z. H., Huang, Z., Wang, R., Koomen, J., Kobayashi, R., Khokhar, A. R., Kuang, J.> ;Oncogene. 2005 Apr 21
• 20 citations
  Model platinum nucleobase and nucleoside complexes and antitumor activity: X-ray crystal structure of [PtIV(trans-1R,2R-diaminocyclohexane)trans-(acetate)2(9-ethylguan...
  Mohammad Ali, S. Rounaq Ali Khan, H. Ojima, Ilse Y. Guzman, Kenton H. Whitmire, Zahid H. Siddik, Abdul R. Khokhar> ;Journal of Inorganic Biochemistry. 2005 Mar 1
• 7 citations
  Increased sensitivity of a metastatic model of prostate cancer to a novel tetravalent platinum analog
  Kalpana Mujoo, Masayuki Watanabe, Abdul R. Khokhar, Zahid H. Siddik> ;The Prostate. 2005 Jan 1
• 20 citations
  Status of p53 phosphorylation and function in sensitive and resistant human cancer models exposed to platinum-based DNA damaging agents
  Kalpana Mujoo, Masayuki Watanabe, Junichi Nakamura, Abdul R. Khokhar, Zahid H. Siddik> ;Journal of Cancer Research and Clinical Oncology. 2003 Sep 26
• 4 citations
  cis-1,4-diaminocyclohexane-Pt(II) and -(IV) adducts with DNA bases and nucleosides.
  Mohammad Ali, Abdul R. Khokhar> ;Journal of Inorganic Biochemistry. 2003 Sep 1
• 20 citations
  Phase I clinical and pharmacological study of intraperitoneal cis-bis-neodecanoato(trans-R, R-1, 2-diaminocyclohexane)-platinum II entrapped in multilamellar liposome ...
  Claire F. Verschraegen, S. Kumagai, R. Davidson, Barry W. Feig, Paul F. Mansfield, Sun Joo Lee, D. S. Maclean, Wei Hu, Abdul R. Khokhar, Zahid H. Siddik> ;Journal of Cancer Research and Clinical Oncology. 2003 Aug 29
• 9 citations
  Preparation, characterization, and antitumor activity of new cisplatin analogues with 1-methyl-4-(methylamino)piperidine: crystal structure of [PtII(1-methyl-4-(methyl...
  Uday Mukhopadhyay, John H. Thurston, Kenton H. Whitmire, Zahid H. Siddik, Abdul R. Khokhar> ;Journal of Inorganic Biochemistry. 2003 Feb 1
• 10 citations
  Bimodal effects of 1R, 2R-diaminocyclohexane(transdiacetato)(dichloro)platinum(IV) on cell cycle checkpoints
  Jian Kuang, Guangan He, Zaifeng Huang, Abdul R. Khokhar, Zahid H. Siddik> ;Clinical Cancer Research. 2001 Nov 1
• 3 citations
  Neutron activation of NDDP, a liposomal platinum antitumor agent
  Donald S. MacLean, Abdul R. Khokhar, Roman Perez-Soler> ;Cancer Biotherapy & Radiopharmaceuticals. 2000 Jun 1
• 28 citations
  Synthesis, characterization and cytotoxicity of new platinum(IV) axial carboxylate complexes: crystal structure of potential antitumor agent [PtIV(trans-1R,2R-diaminoc...
  S. Rounaq Ali Khan, Shurong Huang, S. Shamsuddin, Sadaaki Inutsuka, Kenton H. Whitmire, Zahid H. Siddik, Abdul R. Khokhar> ;Bioorganic & Medicinal Chemistry. 2000 Mar 1
• 9 citations
  Intraliposomal chemical activation patterns of liposomal cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum (II) (L-NDDP)-a potential antitumour agent.
  D. S. MaClean, Abdul R. Khokhar, P. Tyle, Roman Perez-Soler> ;Journal of Microencapsulation. 2000 Jan 1
• 13 citations
  Preparation, characterization, and antitumor activity of new cisplatin analogs with homopiperazines: crystal structure of [PtII(1-methylhomopiperazine)(methylmalonato)...
  Mohammad Ali, Kenton H. Whitmire, Taisuke Toyomasu, Zahid H. Siddik, Abdul R. Khokhar> ;Journal of Inorganic Biochemistry. 1999 Nov 30
• 21 citations
  Role of p53 in the ability of 1,2-diaminocyclohexane-diacetato-dichloro-Pt(IV) to circumvent cisplatin resistance
  Zahid H. Siddik, G. S. Hagopian, Gerald Thai, S. Tomisaki, T. Toyomasu, Abdul R. Khokhar> ;Journal of Inorganic Biochemistry. 1999 Oct 1
• 60 citations
  Expression of p53 in Cisplatin-resistant Ovarian Cancer Cell Lines: Modulation with the Novel Platinum Analogue (1R, 2R-Diaminocyclohexane)(trans-diacetato)(dichloro)-...
  George S. Hagopian, Gordon B. Mills, Abdul R. Khokhar, Robert C. Bast, Zahid H. Siddik> ;Clinical Cancer Research. 1999 Mar 1
• Evaluation of toxicosis of liposome-encapsulated cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum (II) in clinically normal cats.
  Fox, L. E., Toshach, K., Calderwood-Mays, M., Khokhar, A. R., Kubilis, P., Perez-Soler, R., MacEwen, E. G.> ;Am J Vet Res. 1999 Feb
• 3 citations
  Cytotoxicity and tolerance to DNA adducts of alicyclic mixed amine platinum(II) homologs in tumor models sensitive and resistant to cisplatin or tetraplatin
  Motofumi Yoshida, Abdul R. Khokhar, Zahid H. Siddik> ;Oncology Reports. 1998 Sep 1
• 41 citations
  Synthesis, characterization, and antitumor activity of new platinum(IV) trans-carboxylate complexes: Crystal structure of [Pt(cis-1,4-DACH)trans-(acetate)2Cl2]
  S. Shamsuddin, Claudia C. Santillan, Joseph L. Stark, Kenton H. Whitmire, Zahid H. Siddik, Abdul R. Khokhar> ;Journal of Inorganic Biochemistry. 1998 Aug 1
• 11 citations
  Synthesis and Characterization of Novel Axial Dichloroplatinum(IV) Cisplatin Analogues: Crystal Structure of an Axial Dichloro Complex [Pt(cis-1,4-DACH)(trans-Cl2)(CBD...
  S. Shamsuddin, Jaap W. van Hal, Joseph L. Stark, Kenton H. Whitmire, Abdul R. Khokhar> ;Inorganic Chemistry. 1997 Dec 3
• 40 citations
  Phase I clinical and pharmacological study of liposome-entrapped NDDP administered intrapleurally in patients with malignant pleural effusions
  Roman Perez-Soler, Dong M. Shin, Zahid H. Siddik, William K. Murphy, Martin Huber, Jin Soo Lee, Abdul R. Khokhar, Waun Ki Hong> ;Clinical Cancer Research. 1997 Mar 1
• 34 citations
  Chemical and biological studies on a series of novel (trans-(1R,2R)-, trans-(1S,2S)-, and cis-1,2-diaminocyclohexane)platinum(IV) carboxylate complexes.
  Abdul R. Khokhar, S. Al-Baker, S. Shamsuddin, Zahid H. Siddik> ;Journal of Medicinal Chemistry. 1997 Jan 3
• 28 citations
  SYNTHESIS, CHARACTERIZATION, AND ANTITUMOR ACTIVITY OF A SERIES OF NOVEL CISPLATIN ANALOGS WITH CIS-1,4-DIAMINOCYCLOHEXANE AS NONLEAVING AMINE GROUP
  S. Shamsuddin, Ikuo Takahashi, Zahid H. Siddik, Abdul R. Khokhar> ;Journal of Inorganic Biochemistry. 1996 Mar 1
• Join now to see all