AdhamBearMD

PubMed

• Facts and hopes in immunotherapy strategies targeting antigens derived from KRAS mutations.
  Gerald P Linette, Adham S Bear, Beatriz M Carreno> ;Clinical Cancer Research. 2024 Jan 24
• 13 citations
  Expression of inducible factors reprograms CAR-T cells for enhanced function and safety.
  Anže Smole, Alexander Benton, Mathilde A Poussin, Monika A Eiva, Claudia Mezzanotte, Barbara Camisa, Beatrice Greco, Prannda Sharma, Nicholas G Minutolo, Falon Gray, A...> ;Cancer Cell. 2022 Dec 12
• 42 citations
  Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting.
  Adham S. Bear, Tatiana Blanchard, Joseph Cesare, Michael J. Ford, Lee P. Richman, Chong Xu, Miren L. Baroja, Sarah McCuaig, Christina Costeas, Khatuna Gabunia, John Sc...> ;Nature Communications. 2021 Jul 16
• 8 citations
  Adoptive Cellular Therapy for Solid Tumors.
  Adham S. Bear, Joseph A. Fraietta, Vivek Narayan, Mark H. O'Hara, Naomi B. Haas> ;American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 2021 May 19
• 235 citations
  Challenges and Opportunities for Pancreatic Cancer Immunotherapy
  Adham S. Bear, Robert H. Vonderheide, Mark H. O'Hara> ;Cancer Cell. 2020 Dec 14
• 21 citations
  Tumor-Derived Myeloid Cell Chemoattractants and T Cell Exclusion in Pancreatic Cancer.
  Robert H. Vonderheide, Adham S. Bear> ;Frontiers in Immunology. 2020 Nov 10
• 8 citations
  Anti-Tumor Effects after Adoptive Transfer of IL-12 Transposon-Modified Murine Splenocytes in the OT-I-Melanoma Mouse Model
  Daniel L. Galvan, Richard T. O’Neil, Aaron E. Foster, Leslie E. Huye, Adham S. Bear, Cliona M. Rooney, Matthew H. Wilson> ;Plos One. 2015 Oct 16
• 7 citations
  Low rate of infusional toxicity after expanded cord blood transplantation
  Adham S. Bear, Patrick J. Hanley, Doyle Bosque, Conrad Russell Y. Cruz, Indresh Kaur, Hao Liu, Partow Kebriaei, Chitra Hosing, Katayoun Rezvani, Betul Oran, Marcos de ...> ;Cytotherapy. 2014 Aug 1
• 7 citations
  Robust T cell responses to aspergillosis in chronic granulomatous disease: implications for immunotherapy.
  Conrad Russell Y. Cruz, Sharon Lam, Patrick J. Hanley, Adham S. Bear, C. Langston, A. J. Cohen, Hao Liu, Caridad Martinez, Robert A. Krance, Helen E. Heslop, Cliona M....> ;Clinical and Experimental Immunology. 2013 Oct 1
• 6 citations
  An adaptable system for improving transposon-based gene expression in vivo via transient transgene repression
  Joseph E. Doherty, Lauren E. Woodard, Adham S. Bear, Aaron E. Foster, Matthew H. Wilson> ;FASEB Journal. 2013 Sep 1
• 110 citations
  Elimination of metastatic melanoma using gold nanoshell-enabled photothermal therapy and adoptive T cell transfer
  Adham S. Bear, Laura C. Kennedy, Joseph K. Young, Serena K. Perna, Joao Paulo Mattos Almeida, Adam Yuh Lin, Phillip C. Eckels, Rebekah A. Drezek, Aaron E. Foster> ;Plos One. 2013 Jul 23
• 108 citations
  Gold Nanoparticle Delivery of Modified CpG Stimulates Macrophages and Inhibits Tumor Growth for Enhanced Immunotherapy
  Adam Yuh Lin, Joao Paulo Mattos Almeida, Adham S. Bear, Nathan J. Liu, Laureen Luo, Aaron E. Foster, Rebekah A. Drezek> ;Plos One. 2013 May 15
• 50 citations
  High-density sub-100-nm peptide-gold nanoparticle complexes improve vaccine presentation by dendritic cells in vitro
  Adam Yuh Lin, Jessica Lunsford, Adham S. Bear, Joseph K. Young, Phillip C. Eckels, Laureen Luo, Aaron E. Foster, Rebekah A. Drezek> ;Nanoscale Research Letters. 2013 Feb 12
• 41 citations
  Replication-competent retroviruses in gene-modified T cells used in clinical trials: is it time to revise the testing requirements?
  Adham S. Bear, Richard A. Morgan, Kenneth Cornetta, Carl H. June, Gwendolyn Binder-Scholl, Mark E. Dudley, Steven A. Feldman, Steven A. Rosenberg, Sheila A Shurtleff, ...> ;Molecular Therapy. 2012 Feb 1
• 10 citations
  T cells as vehicles for cancer vaccination.
  Adham S. Bear, Conrad Russell Y. Cruz, Aaron E. Foster> ;Journal of Biomedicine & Biotechnology. 2011 Oct 27
• 78 citations
  T cells enhance gold nanoparticle delivery to tumors in vivo
  Laura C. Kennedy, Adham S. Bear, Joseph K. Young, Nastassja Lewinski, Jean Kim, Aaron E. Foster, Rebekah A. Drezek> ;Nanoscale Research Letters. 2011 Apr 4
• 22 citations
  IRAK-M Removal Counteracts Dendritic Cell Vaccine Deficits in Migration and Longevity
  Meghan E. Turnis, Xiao-Tong Song, Adham S. Bear, Aaron E. Foster, Stephen Gottschalk, Malcolm K. Brenner, Si-Yi Chen, Cliona M. Rooney> ;Journal of Immunology. 2010 Oct 1
• 373 citations
  Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b
  John Craddock, An Lu, Adham S. Bear, Martin Pule, Malcolm K. Brenner, Cliona M. Rooney, Aaron E. Foster> ;Journal of Immunotherapy. 2010 Oct 1
• 22 citations
  Genetic Modification of T Cells with IL-21 Enhances Antigen Presentation and Generation of Central Memory Tumor-Specific Cytotoxic T Lymphocytes
  Anjum S. Kaka, Donald R. Shaffer, Ryan Hartmeier, Ann M. Leen, An Lu, Adham S. Bear, Cliona M. Rooney, Aaron E. Foster> ;Journal of Immunotherapy. 2009 Sep 1
• 131 citations
  Abnormal cholesterol metabolism in renal clear cell carcinoma.
  Roger L. Gebhard, R. V. Clayman, W F Prigge, Robert Figenshau, N. A. Staley, C. Reesey, A. Bear> ;Journal of Lipid Research. 1987 Oct 1
• 16 citations
  Characterization of two human cell lines (TK-10, TK-164) of renal cell cancer.
  Amy Bear, Ralph V. Clayman, Jeffrey D. Elbers, Catherine Limas, Nancy Wang, Ken Stone, Roger L. Gebhard, William F. Prigge, James O. Palmer> ;Cancer Research. 1987 Jul 15
• 25 citations
  Transplantation of Human Renal Carcinomas into Athymic Mice
  Ralph V. Clayman, Robert S. Figenshau, Amy Bear, Catherine Limas> ;Cancer Research. 1985 Jun 1
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