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University of Pennsylvania, 3400 Civic Center Blvd.1-Perelman SouthPhiladelphia, PA 19104
Phone+1 215-662-7610
Fax+1 215-615-4966
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Summary
- Dr. Alain Rook is a dermatologist in Philadelphia, PA and is affiliated with Hospital of the University of Pennsylvania. He received his medical degree from University of Michigan Medical School and has been in practice 42 years. He is experienced in general dermatology, cryosurgery, phototherapy, and complex medical dermatology. He has more than 300 publications and over 500 citings.
Education & Training
University of Pennsylvania Health SystemResidency, Dermatology, 1986 - 1989
National Institutes of Health Clinical CenterFellowship, Allergy and Immunology, 1984 - 1986
McGill UniversityFellowship, Nephrology, 1977 - 1979- McGill University Residency, Internal Medicine, 1975 - 1977
University of Michigan Medical SchoolClass of 1975
Certifications & Licensure
PA State Medical License 1986 - 2026
MD State Medical License 1981 - 1993
American Board of Dermatology Dermatology
American Board of Internal Medicine Internal Medicine- American Board of Internal Medicine Nephrology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage Stage 2 Certification Beacon Oncology 2014 Certified Module, Epic Systems Corporation, 2012, 2014, 2016-2017
- CMS Meaningful Use Stage Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2012, 2014, 2016-2017
- CMS Meaningful Use Stage Stage 1 Certification EpicCare Ambulatory - Core EMR, Epic Systems Corporation, 2012, 2014, 2016-2017
Clinical Trials
- Interleukin-12 and Interleukin-2 in Treating Patients With Mycosis Fungoides Start of enrollment: 2002 Sep 01
Publications & Presentations
PubMed
- Harnessing the CD2 axis to broaden and enhance the efficacy of CAR T-cell therapies.Alberto Carturan, Mathew G Angelos, Puneeth Guruprasad, Ruchi P Patel, Raymone Pajarillo
Blood. 2026-01-05 - High-Throughput Sequencing and Estimated Relapse Risk in Patients With Sézary Syndrome.Jeffrey D Weiner, David M Weiner, Bernice Benoit, Jessica E Teague, Rachael A Clark
JAMA Dermatology. 2025-11-01 - Cutaneous T-Cell Lymphoma: Yin-Yang Effects of Transcription Factors HLF and NFIL3 in Regulation of Malignant T-Cell Markers in the Context of HDAC Inhibitor Romidepsi...Andrew V Kossenkov, Noor Dawany, Sonali Majumdar, Celia Chang, Calen Nichols
Cancers. 2025-07-17
Journal Articles
- Brentuximab Vedotin for Relapsed or Refractory Sézary SyndromePaul L Haun, Sara S Samimi, Alain H Rook, Ellen J Kim, JAMA Dermatology
- Low-Dose Total Skin Electron Beam Therapy as Part of a Multimodality Regimen for Treatment of Sézary SyndromeEllen J Kim, Carmela Vittorio, Paul L Haun, Sara S Samimi, Rachael A Clark, Alain H Rook, JAMA Dermatology
Lectures
- Management Issues in Cutaneous LymphomaAmerican Academy of Dermatology - Annual Meeting 2019 - Washington, D.C. - 3/3/2019
Other
- Clinical presentation, pathologic features, and diagnosis of S??zary syndromeRook AH, Olsen EA
http://www.uptodate.com/contents/clinical-presentation-pathologic-features-and-diagnosis-of-sezary-s
UpToDate, Wolters Kluwer Health - 2013-02-05
Press Mentions
'Chromosomal Chaos:' Complex Array of Mutations Found in Rare, Aggressive LeukemiaOctober 7th, 2015
Topical Gel Appears Safe, Effective in CTCLAugust 7th, 2015- Triple Therapy Regime Puts Patients with Leukemic Form of Cutaneous Lymphoma in RemissionAugust 19th, 2011
Grant Support
- Toll Receptor Ligand Therapy Of Cutaneous T-Cell LymphomaNational Cancer Institute2008–2011
- Immunotherapy Of Cutaneous T-Cell Lymphoma With Interleukin-12National Cancer Institute2007–2008
- Dendritic Cell Defects In Cutaneous T-Cell LymphomaNational Cancer Institute2003–2007
- Immunotherapy Of Cutaneous T-Cell Lymphoma WNational Cancer Institute2004–2006
- Recombinant Interleukin-12 For Cutaneous T-Cell LymphomaNational Cancer Institute2001–2006
Professional Memberships
- Fellow
Other Languages
- French
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