AlanSGamisMDMPH

PubMed

• Structural variants involving MLLT10 fusion are associated with adverse outcomes in pediatric acute myeloid leukemia.
  Oussama Abla, Rhonda E Ries, Tim Triche Jr, Robert B Gerbing, Betsy Hirsch, Susana Raimondi, Todd Cooper, Jason E Farrar, Nathaniel Buteyn, Lauren M Harmon, Hong Wen, ...> ;Blood Advances. 2024 Apr 23
• Optimized Cytogenetic Risk-Group Stratification of KMT2A-Rearranged Pediatric Acute Myeloid Leukemia.
  Romy Elise van Weelderen, Christine J Harrison, Kim Klein, Yilin Jiang, Jonas Abrahamsson, Todd Alonzo, Richard Aplenc, Nira Arad-Cohen, Emmanuelle Bart-Delabesse, Bar...> ;Blood Advances. 2024 Apr 15
• Characteristics and treatment of acute myeloid neoplasms with cutaneous involvement in infants up to 6 months of age: A retrospective study.
  Juliette Renaud, Bianca F Goemans, Franco Locatelli, Martina Pigazzi, Shelagh Redmond, Claudia E Kuehni, Alice Destaillats, Todd A Alonzo, Robert B Gerbing, Raffaele R...> ;Pediatric Blood & Cancer. 2024 Apr 14
• Prognostic Impact of Co-occurring Mutations in FLT3-ITD Pediatric Acute Myeloid Leukemia.
  Gerbing, R., Ries, R., Smith, J., Leonti, A., Huang, B., Kirkey, D., Robinson, L., Peplinski, J., Lange, B., Cooper, T., Kolb, E., Pollard, J., Tarlock, K., Gamis, A.,...> ;Blood Advances. 2024 Jan 31
• Genetic variation in DNA damage response pathway and response to Gemtuzumab Ozogamicin in pediatric AML: a report from the Children's Oncology Group.
  Shastri, V., Chauhan, L., Gbadamosi, M., Alonzo, T., Wang, Y., Hirsch, B., Kolb, E., Lamba, J., Aplenc, R., Gamis, A., Meshinchi, S.> ;Clinical Cancer Research. 2024 Jan 10
• Valosin-containing protein (VCP/p97) is prognostically unfavorable in pediatric AML, and negatively correlates with unfolded protein response proteins IRE1 and GRP78: ...
  Fieke W Hoff, Yihua Qiu, Brandon D Brown, Robert B Gerbing, Amanda R Leonti, Rhonda E Ries, Alan S Gamis, Richard Aplenc, Edward Anders Kolb, Todd A Alonzo, Soheil Mes...> ;Proteomics. Clinical Applications. 2023 Nov 1
• 4 citations
  Characteristics and prognostic impact of IDH mutations in AML: a COG, SWOG, and ECOG analysis.
  Sara Zarnegar-Lumley, Todd A Alonzo, Robert B Gerbing, Megan Othus, Zhuoxin Sun, Rhonda E Ries, Jim Wang, Amanda Leonti, Matthew A Kutny, Fabiana Ostronoff, Jerald P R...> ;Blood Advances. 2023 Oct 10
• 8 citations
  Comprehensive molecular and clinical characterization offusions in pediatric acute myeloid leukemia.
  Eline J M Bertrums, Jenny L Smith, Lauren Harmon, Rhonda E Ries, Yi-Cheng J Wang, Todd A Alonzo, Andrew J Menssen, Karen M Chisholm, Amanda R Leonti, Katherine Tarlock...> ;Haematologica. 2023 Aug 1
• 4 citations
  Long Noncoding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia.
  Jason E Farrar, Jenny L Smith, Megan Othus, Benjamin J Huang, Yi-Cheng Wang, Rhonda Ries, Tiffany Hylkema, Era L Pogosova-Agadjanyan, Sneha Challa, Amanda Leonti, Timo...> ;Journal of Clinical Oncology. 2023 Jun 1
• 5 citations
  Pathologic, cytogenetic, and molecular features of acute myeloid leukemia with megakaryocytic differentiation: A report from the Children's Oncology Group.
  Karen M Chisholm, Jenny Smith, Amy E Heerema-McKenney, John K Choi, Rhonda E Ries, Betsy A Hirsch, Susana C Raimondi, Yi-Cheng Wang, Alice Dang, Todd A Alonzo, Lillian...> ;Pediatric Blood & Cancer. 2023 May 1
• 15 citations
  Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia.
  Benjamin J Huang, Jenny L Smith, Jason E Farrar, Yi-Cheng Wang, Masayuki Umeda, Rhonda E Ries, Amanda R Leonti, Erin Crowgey, Scott N Furlan, Katherine Tarlock, Marcos...> ;Nature Communications. 2022 Sep 19
• 31 citations
  Sorafenib in Combination With Standard Chemotherapy for Children With High Allelic Ratio/ITD+ Acute Myeloid Leukemia: A Report From the Children's Oncology Group Proto...
  Jessica A Pollard, Todd A Alonzo, Robert Gerbing, Patrick Brown, Elizabeth Fox, John Choi, Brian Fisher, Betsy Hirsch, Samir Kahwash, Kelly Getz, John Levine, Lisa Eid...> ;Journal of Clinical Oncology. 2022 Jun 20
• 11 citations
  Hematopoietic Cell Transplantation in the Treatment of Pediatric Acute Myelogenous Leukemia and Myelodysplastic Syndromes: Guidelines from the American Society of Tran...
  Katherine Tarlock, Maria Luisa Sulis, Joseph H Chewning, Jessica A Pollard, Todd Cooper, Alan Gamis, Shalini Shenoy, Matthew Kutny, John Horan, Soheil Meshinchi, Jaap-...> ;Transplantation and Cellular Therapy. 2022 Sep 1
• 7 citations
  A ten-gene DNA-damage response pathway gene expression signature predicts gemtuzumab ozogamicin response in pediatric AML patients treated on COGAAML0531 and AAML03P1 ...
  Mohammed O Gbadamosi, Vivek M Shastri, Abdelrahman H Elsayed, Rhonda Ries, Oluwaseyi Olabige, Nam H K Nguyen, Angelica De Jesus, Yi-Cheng Wang, Alice Dang, Betsy A Hir...> ;Leukemia. 2022 Aug 1
• 5 citations
  Adolescent and young adult (AYA) versus pediatric patients with acute leukemia have a significantly increased risk of acute GVHD following unrelated donor (URD) stem c...
  Jeffrey R Andolina, Yi-Cheng Wang, Lingyun Ji, David R Freyer, John E Levine, Michael A Pulsipher, Alan S Gamis, Richard Aplenc, Michael E Roth, Lauren Harrison, Mitch...> ;Bone Marrow Transplantation. 2022 Mar 1
• 4 citations
  Polygenic Ara-C Response Score Identifies Pediatric Patients With Acute Myeloid Leukemia in Need of Chemotherapy Augmentation.
  Abdelrahman H Elsayed, Xueyuan Cao, Amit K Mitra, Huiyun Wu, Susana Raimondi, Christopher Cogle, Zeina Al-Mansour, Raul C Ribeiro, Alan Gamis, Edward Anders Kolb, Rich...> ;Journal of Clinical Oncology. 2022 Mar 1
• 4 citations
  Blood Count Recovery Following Induction Therapy for Acute Myeloid Leukemia in Children Does Not Predict Survival.
  Lauren Pommert, Todd M Cooper, Robert B Gerbing, Lisa Brodersen, Michael Loken, Alan Gamis, Richard Aplenc, Todd A Alonzo, Edward Anders Kolb> ;Cancers. 2022 Jan 26
• 8 citations
  Clinical relevance of proteomic profiling inpediatric acute myeloid leukemia: a Children's Oncology Group study.
  Fieke W Hoff, Anneke D Van Dijk, Yihua Qiu, Chenyue W Hu, Rhonda E Ries, Andrew Ligeralde, Gaye N Jenkins, Robert B Gerbing, Alan S Gamis, Richard Aplenc, E Anders Kol...> ;Haematologica. 2022 Oct 1
• 29 citations
  Assessment of Arsenic Trioxide and All-trans Retinoic Acid for the Treatment of Pediatric Acute Promyelocytic Leukemia: A Report From the Children's Oncology Group AAM...
  Matthew A. Kutny, Todd A. Alonzo, Oussama Abla, Madhvi Rajpurkar, Robert B. Gerbing, Yi-Cheng Wang, Betsy A. Hirsch, Susana C. Raimondi, Samir B. Kahwash, Kristina K. ...> ;JAMA Oncology. 2021 Nov 11
• 3 citations
  Bortezomib is significantly beneficial for de novo pediatric AML patients with low phosphorylation of the NF-κB subunit RelA.
  Anneke D. van Dijk, Fieke W Hoff, Yihua Qiu, Robert B. Gerbing, Alan S. Gamis, Richard Aplenc, E. Anders Kolb, Todd A. Alonzo, Soheil Meshinchi, Gaye Jenkins, Eveline ...> ;Proteomics. Clinical Applications. 2021 Nov 1
• 6 citations
  Outcomes of intensification of induction chemotherapy for children with high-risk acute myeloid leukemia: A report from the Children's Oncology Group
  Caitlin W Elgarten, Andrew C. Wood, Yimei Li, Todd A. Alonzo, Lisa Eidenschink Brodersen, Robert B. Gerbing, Kelly D. Getz, Y-S Vera Huang, Michael R. Loken, Soheil Me...> ;Pediatric Blood & Cancer. 2021 Oct 1
• 4 citations
  CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes.
  Benjamin J. Huang, Jenny L. Smith, Yi-Cheng Wang, Kassra Taghizadeh, Amanda R. Leonti, Rhonda E. Ries, Yanling Liu, Pandurang Kolekar, Katherine Tarlock, Robert B. Ger...> ;Blood Advances. 2021 Dec 14
• 5 citations
  Cytarabine dose reduction in patients with low-risk acute myeloid leukemia: A report from the Children's Oncology Group
  Kelly D. Getz, Todd A. Alonzo, Lillian Sung, Soheil Meshinchi, Robert B. Gerbing, Susana C. Raimondi, Betsy A. Hirsch, Michael R. Loken, Lisa Eidenschink Brodersen, Sa...> ;Pediatric Blood & Cancer. 2022 Jan 1
• 12 citations
  High-dose AraC is Essential for the Treatment of ML-DS Independent of Post-Induction MRD: Results of COG AAML1531.
  Johann Hitzler, Todd A. Alonzo, Robert B. Gerbing, Amy Beckman, Betsy A. Hirsch, Susana C. Raimondi, Karen M. Chisholm, Shelton A Viola, Lisa Eidenschink Brodersen, Mi...> ;Blood. 2021 Jul 28
• 36 citations
  Gemtuzumab Ozogamicin Improves Event-Free Survival and Reduces Relapse in Pediatric KMT2A-Rearranged AML: Results From the Phase III Children's Oncology Group Trial AA...
  Jessica A. Pollard, Erin M. Guest, Todd A. Alonzo, Robert B. Gerbing, Mike R Loken, Lisa Eidenschink Brodersen, E. Anders Kolb, Richard Aplenc, Soheil Meshinchi, Susan...> ;Journal of Clinical Oncology. 2021 May 28
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Abstracts/Posters

• Response to Sorafenib in FLT3/ITD AML Is Depedent on Co-Occurring Mutational Profile
  Alan S Gamis, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Long Non-Coding RNAs (lncRNAs) Are Highly Associated with Disease Characteristics and Outcome in Pediatric Acute Myeloid Leukemia _ a COG and Tpaml Study
  Alan S Gamis, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Area-Based Socioeconomic Disparities in Survival of Children with Newly Diagnosed Acute Myeloid Leukemia: A Report from the ChildrenÍs Oncology Group
  Alan S Gamis, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• High-Dose Cytarabine Is Indispensable for the Survival of Children with Myeloid Leukemia of Down Syndrome Despite Negative Minimal Residual Disease Post-Induction
  Alan S Gamis, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Structural Variants Involving MLLT10/AF10 Are Associated with Adverse Outcome in AML Regardless of the Partner Gene _ a COG/Tpaml Study
  Alan S Gamis, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• CD117 Expression Is Associated with Cytogenetic and Molecular Profiles and Outcome in Pediatric Acute Myeloid Leukemia
  Alan S Gamis, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Occurrence and Resolution of Anthracycline Cardiotoxicity and Impact on Treatment Outcomes Among Children Treated on the AAML1031 Clinical Trial: A Report from the Chi...
  Alan S Gamis, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Somatic Bzip Mutations of CEBPA Are Associated with Favorable Outcome Regardless of Presence As Single Vs. Double Mutation
  Alan S Gamis, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Prognostic Significance of FOXO3 in Pediatric Acute Myeloid Leukemia (AML) Patients Treated with Bortezomib Addition to Standard Therapy: Results from a ChildrenÍs Onc...
  Alan S Gamis, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Sorafenib in Combination with Standard Chemotherapy for Children with High Allelic Ratio FLT3/ITD+ AML Improves Event-Free Survival and Reduces Relapse Risk: A Report ...
  Alan S Gamis, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
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Lectures

• Enhancement of Eligibility Guidelines for Gemtuzumab Ozogamicin Therapy for Childhood Acute Myeloid Leukemia: A Report from Children's Oncology Group Protocol AAML0531 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018