AlanCharlesHartfordMDPhD, FACR

Radiation Oncology • Lebanon, NH

Professor of Medicine (Radiation Oncology), Geisel School of Medicine at Dartmouth

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Office
Dartmouth-Hitchcock Medical Center
One Medical Center Drive
Lebanon, NH 03756
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Education & Training

Brigham and Women's Hospital/Massachusetts General Hospital/Harvard Medical SchoolResidency, Radiation Oncology, 1993 - 1997
Beth Israel Deaconess Medical CenterInternship, Internal Medicine, 1992 - 1993
Harvard Medical SchoolClass of 1992

Certifications & Licensure

MA State Medical License 1996 - 2026
NH State Medical License 2004 - 2024
VT State Medical License 2007 - 2024
American Board of Radiology Radiation Oncology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2012-2014
America's Top Doctors for Cancer Castle Connolly, 2011-2013
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011

Clinical Trials

Interstitial Brachytherapy With or Without External-Beam Radiation Therapy in Treating Patients With Prostate Cancer Start of enrollment: 2003 Jun 01
Completed
Phase 3
Paclitaxel and Radiation Therapy With or Without Trastuzumab in Treating Patients Who Have Undergone Surgery for Bladder Cancer Start of enrollment: 2005 Jul 26
Completed
Phase 1, Phase 2
Prostate Radiation Therapy or Short-Term Androgen Deprivation Therapy and Pelvic Lymph Node Radiation Therapy With or Without Prostate Radiation Therapy in Treating Patients With a Rising Prostate Specific Antigen (PSA) After Surgery for Prostate Cancer Start of enrollment: 2008 Feb 01
Active, not recruiting
Phase 3
Paclitaxel, Cisplatin, and Radiation Therapy With or Without Cetuximab in Treating Patients With Locally Advanced Esophageal Cancer Start of enrollment: 2008 Jun 01
Completed
Phase 3
Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer Start of enrollment: 2009 Sep 01
Active, not recruiting
Phase 3
Radiation Therapy With or Without Cetuximab in Treating Patients Who Have Undergone Surgery for Locally Advanced Head and Neck Cancer Start of enrollment: 2009 Nov 01
Active, not recruiting
Phase 3
Radiation Therapy and Chemotherapy in Treating Patients With Stage I Bladder Cancer Start of enrollment: 2009 Nov 01
Completed
Phase 2
Radiation Therapy With Cisplatin or Cetuximab in Treating Patients With Oropharyngeal Cancer Start of enrollment: 2011 Jun 01
Active, not recruiting
Phase 3
Higher Per Daily Treatment-Dose Radiation Therapy or Standard Per Daily Treatment Radiation Therapy in Treating Patients With Early-Stage Breast Cancer That Was Removed by Surgery Start of enrollment: 2011 May 01
Active, not recruiting
Phase 3
Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer Start of enrollment: 2012 May 01
Active, not recruiting
Phase 3
A Proof-of-principle Study of HBO-SRS for Brain Metastases Start of enrollment: 2013 Jul 01
Completed
Not Applicable
Standard or Comprehensive Radiation Therapy in Treating Patients With Early-Stage Breast Cancer Previously Treated With Chemotherapy and Surgery Start of enrollment: 2013 Aug 01
Active, not recruiting
Not Applicable
Artificial Intelligence for Prostate Cancer Treatment Planning Start of enrollment: 2020 Jun 22
Completed
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

A Confederacy of Dunces: A Lesson in Genius.
Hartford, A.> ;Practical Radiation Oncology. 2024 Mar 2
Cardiovascular Mortality and Duration of Androgen Deprivation in Locally Advanced Prostate Cancer: Long-term Update of NRG/RTOG 9202.
Mak, K., Scannell Bryan, M., Dignam, J., Shipley, W., Lin, Y., Peters, C., Gore, E., Rosenthal, S., Zeitzer, K., D'Souza, D., Horwitz, E., Pisansky, T., Maier, J., Cha...> ;European Urology Focus. 2024 Feb 1
2 citations
Effects of Androgen Deprivation Therapy on Prostate Cancer Outcomes According to Competing Event Risk: Secondary Analysis of a Phase 3 Randomised Trial.
Loren K Mell, Stephanie L Pugh, Christopher U Jones, Tyler J Nelson, Kaveh Zakeri, Brent S Rose, Kenneth L Zeitzer, Elizabeth M Gore, Jean-Paul Bahary, Luis Souhami, J...> ;European Urology. 2024 Apr 1
Dune: A Lesson in Vision.
Alan C Hartford> ;Practical Radiation Oncology. 2023 Jan 5
7 citations
Analysis of a Biopsy-Based Genomic Classifier in High-Risk Prostate Cancer: Meta-Analysis of the NRG Oncology/Radiation Therapy Oncology Group 9202, 9413, and 9902 Pha...
Paul L Nguyen, Huei-Chung Rebecca Huang, Daniel E Spratt, Elai Davicioni, Howard M Sandler, William U Shipley, Jason A Efstathiou, Jeffry P Simko, Alan Pollack, Adam P...> ;International Journal of Radiation Oncology, Biology, Physics. 2023 Jul 1
A Man's Place: A Lesson in Observation.
Alan C Hartford> ;Practical Radiation Oncology. 2022 Dec 17
1 citations
Sensitizing brain metastases to stereotactic radiosurgery using hyperbaric oxygen: A proof-of-principle study.
Alan C Hartford, Gobind S Gill, Divya Ravi, Tor D Tosteson, Zhongze Li, Gregory Russo, Clifford J Eskey, Lesley A Jarvis, Nathan E Simmons, Linton T Evans, Benjamin B ...> ;Radiotherapy and Oncology. 2022 Dec 1
Never Let Me Go: A Lesson in Humanity.
Alan C Hartford> ;Practical Radiation Oncology. 2022 May 5
16 citations
Adding Short-Term Androgen Deprivation Therapy to Radiation Therapy in Men With Localized Prostate Cancer: Long-Term Update of the NRG/RTOG 9408 Randomized Clinical Tr...
Christopher U. Jones, Stephanie L. Pugh, Howard M. Sandler, Michael Chetner, Mahul B. Amin, Deborah Watkins Bruner, Anthony L. Zietman, Robert B. Den, Mark H. Leibenha...> ;International Journal of Radiation Oncology, Biology, Physics. 2021 Sep 1
32 citations
Randomized Phase III Trial Evaluating Radiation Following Surgical Excision for Good-Risk Ductal Carcinoma In Situ: Long-Term Report From NRG Oncology/RTOG 9804.
Beryl McCormick, Kathryn Winter, Wendy A. Woodward, Henry Mark Kuerer, Nour Sneige, Eileen Rakovitch, Barbara L. Smith, Isabelle Germain, Alan C. Hartford, Mark Allen ...> ;Journal of Clinical Oncology. 2021 Aug 18
The Boys in the Boat: A Lesson About Teamwork.
Alan C. Hartford> ;Practical Radiation Oncology. 2021 May 1
4 citations
ACR-ABS-ACNM-ASTRO-SIR-SNMMI practice parameter for selective internal radiation therapy or radioembolization for treatment of liver malignancies.
Kelvin Hong, Olaguoke Akinwande, Lisa Bodei, Murthy Rk Chamarthy, Phillip M. Devlin, Shana Elman, Suvranu Ganguli, Andrew S. Kennedy, Sonya J. Koo, Zoubir Ouhib, Siddh...> ;Brachytherapy. 2021 May 1
All the Light We Cannot See: A Lesson in Humility.
Alan C. Hartford> ;Practical Radiation Oncology. 2021 Mar 12
14 citations
ACR-ASTRO Practice Parameter for the Performance of Stereotactic Body Radiation Therapy.
Samuel T. Chao, Luqman K. Dad, Laura A. Dawson, Neil Desai, Matthew Pacella, Ramesh Rengan, Ying Xiao, Kamil M. Yenice, Seth A. Rosenthal, Alan C. Hartford> ;American Journal of Clinical Oncology. 2020 Aug 1
9 citations
ACR-ASTRO Practice Parameter for Communication: Radiation Oncology
Naomi R. Schechter, Derek Brown, Joseph Bovi, Michael M. Dominello, Arthur K Liu, Malcolm D. Mattes, Jeff M. Michalski, Helen A. Shih, Eric A. Strom, J B Wilkinson, Se...> ;American Journal of Clinical Oncology. 2020 Aug 1
12 citations
ACR-ASTRO Practice Parameter for Image-guided Radiation Therapy (IGRT).
Join Y. Luh, Kevin V. Albuquerque, Cheewai Cheng, Ralph P. Ermoian, Nima Nabavizadeh, Homayon Parsai, John C. Roeske, Stephanie E. Weiss, Raymond B. Wynn, Yan Yu, Seth...> ;American Journal of Clinical Oncology. 2020 Jul 1
ACR-ASTRO Practice Parameter for the Performance of Proton Beam Radiation Therapy.
Helen A. Shih, Ramesh Rengan, Smith Apisarnthanarax, Chee-Wai Cheng, J Daartz, Thomas F. DeLaney, William F. Hartsell, Daniel J. Indelicato, Sameer R. Keole, Seth A. R...> ;American Journal of Clinical Oncology. 2020 Mar 1
18 citations
Experimentally Observed Cherenkov Light Generation in the Eye During Radiation Therapy
Irwin I. Tendler, Alan C. Hartford, Michael Jermyn, Ethan P. M. LaRochelle, Xu Cao, Victor Borza, Daniel A. Alexander, Petr Bruza, Jack Hoopes, Karen L Moodie, Brian P...> ;International Journal of Radiation Oncology, Biology, Physics. 2020 Feb 1
5 citations
Gleason pattern 5 is associated with an increased risk for metastasis following androgen deprivation therapy and radiation: An analysis of RTOG 9202 and 9902.
Daniel A. Hamstra, Stephanie L. Pugh, Herbert Lepor, Seth A. Rosenthal, Kenneth J. Pienta, Leonard G. Gomella, Christopher A. Peters, David D'Souza, Kenneth L. Zeitzer...> ;Radiotherapy and Oncology. 2019 Dec 1
9 citations
Phase 2 Study of Radiation Therapy Plus Low-Dose Temozolomide Followed by Temozolomide and Irinotecan for Glioblastoma: NRG Oncology RTOG Trial 0420.
Frank S. Lieberman, Meihua Wang, H. Ian Robins, Christina I. Tsien, Walter J. Curran, Maria Werner-Wasik, Ryan P. Smith, Christopher J. Schultz, Alan C. Hartford, Peix...> ;International Journal of Radiation Oncology, Biology, Physics. 2019 Mar 15
140 citations
Sequence of hormonal therapy and radiotherapy field size in unfavourable, localised prostate cancer (NRG/RTOG 9413): long-term results of a randomised, phase 3 trial
Mack Roach, Jennifer Moughan, Colleen A. Lawton, Adam P. Dicker, Kenneth L. Zeitzer, Elizabeth Gore, Young Kwok, Michael J. Seider, I-Chow Hsu, Alan C. Hartford, Eric ...> ;The Lancet. Oncology. 2018 Nov 1
24 citations
NRG oncology RTOG 9006: a phase III randomized trial of hyperfractionated radiotherapy (RT) and BCNU versus standard RT and BCNU for malignant glioma patients
Arif Ali, Peixin Zhang, W. K. Alfred Yung, Yuhchyau Chen, Benjamin Movsas, Raul C. Urtasun, Christopher U. Jones, Kwang N. Choi, Jeff M. Michalski, A. Jennifer Fischba...> ;Journal of Neuro-Oncology. 2018 Mar 1
6 citations
American College of Radiology-American Brachytherapy Society practice parameter for electronically generated low-energy radiation sources.
Phillip M. Devlin, Laurie E. Gaspar, Ivan Buzurovic, D. Jeffrey Demanes, Michael Kasper, Subir Nag, Zoubir Ouhib, Joshua Petit, Seth A. Rosenthal, William Small, Paul ...> ;Brachytherapy. 2017 Nov 1
7 citations
Genetic landscape of extreme responders with anaplastic oligodendroglioma.
Matthias Holdhoff, Gregory Cairncross, Thomas M. Kollmeyer, Ming Zhang, Peixin Zhang, Minesh P. Mehta, Maria Werner-Wasik, Luis Souhami, Jean-Paul Bahary, Young Kwok, ...> ;Oncotarget. 2017 Apr 1
19 citations
The American College of Radiology and the American Brachytherapy Society practice parameter for transperineal permanent brachytherapy of prostate cancer.
Nathan Bittner, Peter F. Orio, Gregory S. Merrick, Bradley R. Prestidge, Alan C. Hartford, Seth A. Rosenthal> ;Brachytherapy. 2017 Jan 1
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Authored Content

ACR 2021 in BriefMay 2021
Perspectives from Council of Affiliated Regional Radiation Oncology SocietiesJune 2019
Perspectives from Council of Affiliated Regional Radiation Oncology SocietiesJune 2019

Press Mentions

Dr. Alan Hartford Selected to Be Inducted into IAOTP’s Hall of FameSeptember 6th, 2021
ACR 2021 in BriefMay 24th, 2021
Dartmouth Physician-Scientists Examine Efficacy of Radiation Therapy in 'Good-Risk' DCIS PatientsFebruary 12th, 2016