AlanGRosmarinMD

Oncology • Worcester, MA

Hematologic Oncology

Professor, Medicine, University Massachusetts Medical School

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Office
55 Lake Ave N
Worcester, MA 01655
Phone+1 508-856-3550
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Summary

Dr. Alan Rosmarin, MD is an oncologist in Worcester, Massachusetts. He is currently licensed to practice medicine in Massachusetts and Rhode Island. He is affiliated with UMass Memorial Medical Center, MetroWest Medical Center, and Baystate Wing Hospital.

Education & Training

Beth Israel Deaconess Medical CenterFellowship, Hematology and Medical Oncology, 1984 - 1988
Beth Israel Deaconess Medical CenterResidency, Internal Medicine, 1981 - 1984
Rutgers Robert Wood Johnson Medical SchoolClass of 1981

Certifications & Licensure

MA State Medical License 1984 - 2021
RI State Medical License 1989 - 2012

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
Meaningful Use Stage 1 Certification Centers for Medicare & Medicaid Services, 2011

Clinical Trials

Safety of Zileuton (Zyflo) in Combination With Imatinib Mesylate (Gleevec) in CML. Start of enrollment: 2010 Jan 01
Terminated
Phase 1
Collection of Blood and/or Bone Marrow for Investigation and Characterization of Normal and Abnormal Cell Growth Start of enrollment: 2009 Sep 01
Recruiting
Rituximab and Combination Chemotherapy With or Without Lenalidomide in Treating Patients With Newly Diagnosed Stage II-IV Diffuse Large B Cell Lymphoma Start of enrollment: 2013 Aug 27
Active, not recruiting
Phase 2

Publications & Presentations

PubMed

5 citations
Identifying monoclonal gammopathy of undetermined significance in electronic health data
Mara M. Epstein, Cassandra Saphirak, Yanhua Zhou, Candace LeBlanc, Alan G. Rosmarin, Arlene S. Ash, Sonal Singh, Kimberly A. Fisher, Brenda M. Birmann, Jerry H. Gurwitz> ;Pharmacoepidemiology and Drug Safety. 2020 Jan 1
2 citations
Hypercalcemia due to Primary Hepatic Lymphoma.
Andrew R. Hsu, Michael Gagnier, Elizabeth Ryer, Mohammed Salhab, Alan G. Rosmarin> ;Case Reports in Hematology. 2016 Dec 25
8 citations
Cooperative Activity of GABP with PU.1 or C/EBPε Regulates Lamin B Receptor Gene Expression, Implicating Their Roles in Granulocyte Nuclear Maturation
Krishnakumar Malu, Rahul Garhwal, Margery G.H. Pelletier, Deepali Gotur, Stephanie Halene, Monika Zwerger, Zhong-Fa Yang, Alan G. Rosmarin, Peter Gaines> ;Journal of Immunology. 2016 Jun 24
31 citations
Factors influencing survival among Kenyan children diagnosed with endemic Burkitt lymphoma between 2003 and 2011: A historical cohort study
Geoffrey Buckle, Louise Maranda, Jodi L. Skiles, John M. Ong’echa, Joslyn Foley, Mara M. Epstein, Terry A. Vik, Andrew Schroeder, Jennifer Lemberger, Alan G. Rosmarin,...> ;International Journal of Cancer. 2016 Sep 15
7 citations
Epigenetic Landscape of Acute Myelogenous Leukemia—Moving Toward Personalized Medicine
Gurpreet Lamba, Sayyed K. Zaidi, Kimberly P. Luebbers, Claire F. Verschraegen, Gary S. Stein, Alan G. Rosmarin> ;Journal of Cellular Biochemistry. 2014 Oct 1
60 citations
GABP Transcription Factor (Nuclear Respiratory Factor 2) Is Required for Mitochondrial Biogenesis
Zhong-Fa Yang, Karen Drumea, Stephanie Mott, Junling Wang, Alan G. Rosmarin> ;Molecular and Cellular Biology. 2014 Sep 1
20 citations
GABP transcription factor is required for development of chronic myelogenous leukemia via its control of PRKD2
Zhong-Fa Yang, Haojian Zhang, Leyuan Ma, Cong Peng, Yaoyu Chen, Junling Wang, Michael R. Green, Shaoguang Li, Alan G. Rosmarin> ;Proceedings of the National Academy of Sciences of the United States of America. 2013 Feb 5
15 citations
PU.1 Is Essential for CD11c Expression in CD8+/CD8− Lymphoid and Monocyte-Derived Dendritic Cells during GM-CSF or FLT3L-Induced Differentiation
Xuejun Zhu, Zhong-Fa Yang, Yaoyu Chen, Junling Wang, Alan G. Rosmarin> ;Plos One. 2012 Dec 20
40 citations
Expression of CD25 independently predicts early treatment failure of acute myeloid leukaemia (AML)
Jan Cerny, Hongbo Yu, Muthalagu Ramanathan, Glen D. Raffel, William V. Walsh, Natasha Fortier, Lindsey Shanahan, Elizabeth O'Rourke, Jayde Bednarik, Bruce A. Barton, A...> ;British Journal of Haematology. 2013 Jan 1
17 citations
Why does my patient have leukocytosis
Jan Cerny, Alan G. Rosmarin> ;Hematology/oncology Clinics of North America. 2012 Apr 1
1 citations
Phase I trial examining addition of gemcitabine to CHOP in intermediate grade NHL
John L. Reagan, Alan G. Rosmarin, James N. Butera, Ahmed Nadeem, Fred J. Schiffman, William M. Sikov, Eric P. Winer, Anthony Mega> ;Cancer Chemotherapy and Pharmacology. 2011 Jul 15
25 citations
GABP transcription factor is required for myeloid differentiation, in part, through its control of Gfi-1 expression.
Zhong Fa Yang, Karen Drumea, James Cormier, Junling Wang, Xuejun Zhu, Alan G. Rosmarin> ;Blood. 2010 Nov 19
12 citations
Retrospective analysis of the efficacy of gemcitabine for previously treated AIDS-associated Kaposi's sarcoma in western Kenya.
R. Matthew Strother, Kelly M. Gregory, Sonak D. Pastakia, Pamela A. Were, Constance Tenge, Naftali Busakhala, Beatrice Jakait, Ellen M. Schellhase, Alan G. Rosmarin, P...> ;Oncology. 2010 Mar 6
98 citations
PTEN is a tumor suppressor in CML stem cells and BCR-ABL-induced leukemias in mice.
Cong Peng, Yaoyu Chen, Zhong-Fa Yang, Haojian Zhang, Lori Osterby, Alan G. Rosmarin, Shaoguang Li> ;Blood. 2010 Jan 21
Tumor registry versus physician medical record review: A head-to-head comparison of malignant pancreatic neuroendocrine tumor (mPNET) cases.
Manasanch EE, McDade TP, Bodnari A, McKinney J, Sullivan ME, Whalen GF, Piperdi B, Rosmarin AG, Tseng JF> ;J. Clin. Oncol.. 2009-05-20
Gemcitabine for previously treated AIDS-related Kaposi's sarcoma: The Western Kenya experience.
Gregory KM, Strother RM, Pastakia S, Were P, Tenge C, Busakhala N, Jakait B, Schellhase EM, Rosmarin AG, Loehrer PJ> ;J. Clin. Oncol.. 2008-05-20
17 citations
Retinoic acid signaling in myelopoiesis.
Karen Drumea, Zhong-Fa Yang, Alan G. Rosmarin> ;Current Opinion in Hematology. 2008 Jan 1
85 citations
The Ets transcription factor GABP is required for cell-cycle progression.
Zhong-Fa Yang, Stephanie Mott, Alan G. Rosmarin> ;Nature Cell Biology. 2007 Feb 4
23 citations
GA-binding protein and p300 are essential components of a retinoic acid-induced enhanceosome in myeloid cells.
Karen K. Resendes, Alan G. Rosmarin> ;Molecular and Cellular Biology. 2006 Apr 15
106 citations
Transcriptional regulation in myelopoiesis: Hematopoietic fate choice, myeloid differentiation, and leukemogenesis
Alan G. Rosmarin, Zhong-Fa Yang, Karen K. Resendes> ;Experimental Hematology. 2005 Feb 1
Expression of key signaling molecules in resected pancreatic cancer.
Resnick M, Cohen-Uram M, Smith B, Iannitti D, Reinert S, Rosmarin A, Safran H> ;J. Clin. Oncol.. 2004-07-15
28 citations
Sp1 control of gene expression in myeloid cells.
Karen K. Resendes, Alan G. Rosmarin> ;Critical Reviews in Eukaryotic Gene Expression. 2004 Jan 1
160 citations
GA-binding protein transcription factor: a review of GABP as an integrator of intracellular signaling and protein-protein interactions.
Alan G. Rosmarin, Karen K. Resendes, Zhong-Fa Yang, John N McMillan, Shawna L Fleming> ;Blood Cells, Molecules & Diseases. 2004 Jan 1
41 citations
GA-binding protein (GABP) and Sp1 are required, along with retinoid receptors, to mediate retinoic acid responsiveness of CD18 (beta 2 leukocyte integrin): a novel mec...
Thomas S. Bush, Michele St. Coeur, Karen K. Resendes, Alan G. Rosmarin> ;Blood. 2003 Jan 1
21 citations
Sp1 and the ets-related transcription factor complex GABPα/β functionally cooperate to activate the utrophin promoter
Mads Gyrd-Hansen, Thomas O.B. Krag, Alan G. Rosmarin, Tejvir S. Khurana> ;Journal of the Neurological Sciences. 2002 May 15
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Press Mentions

NCI Releases 2020 Annual Plan and Budget ProposalDecember 1st, 2018

Professional Memberships

American Society of Clinical Oncology - ASCO
Member

Hospital Affiliations

UMass Memorial Medical CenterWorcester, Massachusetts
Baystate Wing HospitalPalmer, Massachusetts
MetroWest Medical CenterFramingham, Massachusetts