AlanP.VenookMD

Oncology • San Francisco, CA

Gastrointestinal Cancer, Hematologic Oncology

Professor of Medicine, UCSF

Join to view full profile

Dr. Venook is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Venook's full profile

Already have an account?

Office
1825 4th St
San Francisco, CA 94143
Phone+1 415-353-9888

Fax+1 415-353-9931
Is this information wrong?

Summary

Dr. Alan Venook is a nationally renowned expert in colorectal and liver cancers at the UCSF Helen Diller Family Comprehensive Cancer Center where he leads the Gastrointestinal Oncology program. In his research, he focuses on treating liver tumors with directed approaches, including infusional chemotherapy and biological agents.

Venook earned a medical degree at UCSF in 1980. He spent two years in the Public Health Service following an internship in internal medicine at UCSF. He completed a residence in internal medicine at the University of California, Davis and a fellowship in hematology and oncology at UCSF. Venook, who has been on the medical staff at UCSF since 1988, is a professor of medicine in hematology and oncology.

Education & Training

University of California (San Francisco)Fellowship, Hematology and Medical Oncology, 1985 - 1988
University of California Davis HealthResidency, Internal Medicine, 1983 - 1985
University of California San Francisco School of MedicineClass of 1980

Certifications & Licensure

CA State Medical License 1981 - 2024
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Hematology
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2009-2014
America's Top Doctors for Cancer Castle Connolly, 2005-2013
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
Super Doctor SuperDoctors.com
Join now to see all

Clinical Trials

Irinotecan in Treating Patients With Solid Tumors or Lymphoma Who Have Abnormal Liver or Kidney Function or Who Have Received Radiation Therapy to the Pelvis Start of enrollment: 1998 Jun 01
Completed
Phase 1
FOLFIRI or FOLFOX With or Without Cetuximab in Patients With Metastatic Adenocarcinoma of the Colon or Rectum Start of enrollment: 2003 Dec 01
Terminated
Phase 3
Cetuximab and/or Bevacizumab Combined With Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer Start of enrollment: 2005 Nov 01
Completed
Phase 3
Celecoxib and Erlotinib in Treating Patients With Liver Cancer Start of enrollment: 2005 Jan 01
Withdrawn
Phase 1, Phase 2
Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery Start of enrollment: 2009 Oct 28
Completed
Phase 3
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma Start of enrollment: 2009 Nov 17
Completed
Phase 1
Sorafenib Tosylate With or Without Doxorubicin Hydrochloride in Treating Patients With Locally Advanced or Metastatic Liver Cancer Start of enrollment: 2010 Feb 15
Completed
Phase 3
Relationship Between Vitamin D Biomarkers and Survival in Blood Samples From Patients With Advanced Pancreatic Cancer Start of enrollment: 2011 Jun 01
Completed
PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery Start of enrollment: 2012 Jun 12
Active, not recruiting
Phase 2, Phase 3
Study of (1) Everolimus, (2) Estrogen Deprivation Therapy (EDT) With Leuprolide + Letrozole and (3) Everolimus + EDT in Patients With Unresectable Fibrolamellar Hepatocellular Carcinoma (FLL-HCC) Start of enrollment: 2012 Jul 12
Completed
Phase 2
Phase II Combination of Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma Start of enrollment: 2012 Oct 05
Completed
Phase 2
Join now to see all

Publications & Presentations

PubMed

q-Diffusion leverages the full dimensionality of gene coexpression in single-cell transcriptomics.
Myrl G Marmarelis, Russell Littman, Francesca Battaglin, Donna Niedzwiecki, Jose-Luis Ambite, Aram Galstyan, Greg Ver Steeg, Alan Venook, Heinz-Josef Lenz> ;Communications Biology. 2024 Apr 2
Gene expression biomarkers differentiate overall survival of colorectal cancer upon targeted therapies.
Akram Yazdani, Azam Yazdani, Raul Mendez-Giraldez, Gianluigi Pillonetto, Esmat Samiei, Reza Hadi, Ahmad Samiei, Andrew Nixon, Monica Bertagnolli, Charles Perou, Federi...> ;Research Square. 2024 Mar 11
Gene Expression Levels Are Predictive and Prognostic in Patients With Metastatic Colorectal Cancer Enrolled in CALGB/SWOG 80405.
Battaglin, F., Ou, F., Qu, X., Niedzwiecki, D., Zemla, T., Blanke, C., Kabbarah, O., Innocenti, F., Hochster, H., Goldberg, R., Mayer, R., Ashouri, K., Venook, A., Len...> ;Journal of Clinical Oncology. 2024 Mar 8
Evaluation of Culture Conducive to Academic Success by Gender at a Comprehensive Cancer Center.
Keenan, B., Sibley, A., Zhang, L., Westring, A., Velazquez, A., Bank, E., Bergsland, E., Boreta, L., Conroy, P., Daras, M., Hermiston, M., Hsu, G., Paris, P., Piawah, ...> ;The Oncologist. 2024 Mar 4
CALGB 80802 (Alliance): Impact of Sorafenib with and without Doxorubicin on Hepatitis C Infection in Patients with Advanced Hepatocellular Carcinoma.
Abou-Alfa, G., Geyer, S., Nixon, A., Innocenti, F., Shi, Q., Kumthekar, P., Jacobson, S., El Dika, I., Yaqubie, A., Lopez, J., Huang, B., Tang, Y., Wen, Y., Schwartz, ...> ;Cancer Research Communications. 2024 Mar 7
Predictive value of CDC37 gene expression for targeted therapy in metastatic colorectal cancer.
Hiroyuki Arai, Yan Yang, Yasmine Baca, Joshua Millstein, Tadamichi Denda, Fang-Shu Ou, Federico Innocenti, Hiroyuki Takeda, Yohei Kubota, Ayako Doi, Yoshiki Horie, Kum...> ;European Journal of Cancer. 2024 Apr 1
andgene expression in colorectal cancer: comprehensive profiling and clinical value.
Francesca Battaglin, Yasmine Baca, Joshua Millstein, Yan Yang, Joanne Xiu, Hiroyuki Arai, Jingyuan Wang, Fang-Shu Ou, Federico Innocenti, Shannon M Mumenthaler, Priya ...> ;Journal for Immunotherapy of Cancer. 2024 Jan 11
Common variation in a long non-coding RNA gene modulates variation of circulating TGF-2 levels in metastatic colorectal cancer patients (Alliance).
Quintanilha, J., Sibley, A., Liu, Y., Niedzwiecki, D., Halabi, S., Rogers, L., O'Neil, B., McLeod, H., Nixon, A., Innocenti, F., Owzar, K., Kindler, H., Kelly, W., Ven...> ;Medrxiv. 2023 Dec 4
DNA Mutational Profiling in Patients With Colorectal Cancer Treated With Standard of Care Reveals Differences in Outcome and Racial Distribution of Mutations.
Federico Innocenti, Wancen Mu, Xueping Qu, Fang-Shu Ou, Omar Kabbarah, Charles David Blanke, Alan P Venook, Heinz-Josef Lenz, Naim U Rashid> ;Journal of Clinical Oncology. 2024 Feb 1
Associations between the Gut Microbiota, Race, and Ethnicity of Patients with Colorectal Cancer: A Pilot and Feasibility Study.
Sorbarikor Piawah, Than S Kyaw, Kai Trepka, Anita L Stewart, Rosa V Mora, Dalila Stanfield, Kendall Levine, Erin L Van Blarigan, Alan Venook, Peter J Turnbaugh, Tung N...> ;Cancers. 2023 Sep 13
Physical activity in recurrent colon cancer: Cancer and Leukemia Group B/SWOG 80702 (Alliance).
Justin C Brown, Chao Ma, Qian Shi, Tyler Zemla, Felix Couture, Philip Kuebler, Pankaj Kumar, Benjamin Tan, Smitha Krishnamurthi, Victor Chang, Richard M Goldberg, Alan...> ;Cancer. 2023 Dec 1
Evaluation of Intratumoral Response Heterogeneity in Metastatic Colorectal Cancer and Its Impact on Patient Overall Survival: Findings from 10,551 Patients in the ARCA...
Fang-Shu Ou, Daniel H Ahn, Jesse G Dixon, Axel Grothey, Yiyue Lou, Pashtoon M Kasi, Joleen M Hubbard, Eric Van Cutsem, Leonard B Saltz, Hans-Joachim Schmoll, Richard M...> ;Cancers. 2023 Aug 15
1 citations
Variety of Fruit and Vegetables and Alcohol Intake are Associated with Gut Microbial Species and Gene Abundance in Colorectal Cancer Survivors.
Than S Kyaw, Vaibhav Upadhyay, Irina Tolstykh, Katherine Van Loon, Angela Laffan, Dalila Stanfield, Daryll Gempis, Stacey A Kenfield, June M Chan, Sorbarikor Piawah, C...> ;The American Journal of Clinical Nutrition. 2023 Sep 1
Barriers and confidence among colorectal and prostate cancer survivors participating in two behavioral intervention studies.
Vivian N Liu, Kyle B Zuniga, Alan Paciorek, Li Zhang, June M Chan, Peter R Carroll, Katherine Van Loon, Angela Laffan, Alan Venook, Erin L Van Blarigan, Stacey A Kenfield> ;Supportive Care in Cancer. 2023 Jul 10
17 citations
NCCN Guidelines® Insights: Biliary Tract Cancers, Version 2.2023.
Al B Benson, Michael I D'Angelica, Thomas Abrams, Daniel E Abbott, Aijaz Ahmed, Daniel A Anaya, Robert Anders, Chandrakanth Are, Melinda Bachini, David Binder, Mitesh ...> ;Journal of the National Comprehensive Cancer Network. 2023 Jul 1
1 citations
Flashback Foreword: IFL/FOLFOX/IROX in Advanced Colorectal Cancer and FOLFIRI and FOLFOX6 in Colorectal Cancer.
Alan P Venook> ;Journal of Clinical Oncology. 2023 Jul 1
Plasma 25-Hydroxyvitamin D Levels and Survival in Stage III Colon Cancer: Findings from CALGB/SWOG 80702 (Alliance).
Qiao-Li Wang, Chao Ma, Chen Yuan, Qian Shi, Brian M Wolpin, Yin Zhang, Charles S Fuchs, Jeffrey Meyer, Tyler Zemla, En Cheng, Priya Kumthekar, Katherine A Guthrie, Fel...> ;Clinical Cancer Research. 2023 Jul 14
17 citations
Patient-Reported Outcomes During and After Treatment for Locally Advanced Rectal Cancer in the PROSPECT Trial (Alliance N1048).
Ethan Basch, Amylou C Dueck, Sandra A Mitchell, Harvey Mamon, Martin Weiser, Leonard Saltz, Marc Gollub, Lauren Rogak, Brenda Ginos, Gina L Mazza, Brian Colgrove, Geor...> ;Journal of Clinical Oncology. 2023 Jul 20
4 citations
Anal Carcinoma, Version 2.2023, NCCN Clinical Practice Guidelines in Oncology.
Al B Benson, Alan P Venook, Mahmoud M Al-Hawary, Nilofer Azad, Yi-Jen Chen, Kristen K Ciombor, Stacey Cohen, Harry S Cooper, Dustin Deming, Ignacio Garrido-Laguna, Jea...> ;Journal of the National Comprehensive Cancer Network. 2023 Jun 1
Plasma 25-hydroxyvitamin D levels and survival in stage III colon cancer: Findings from CALGB/SWOG 80702 (Alliance).
Qiao-Li Wang, Chao Ma, Chen Yuan, Qian Shi, Brian M Wolpin, Yin Zhang, Charles S Fuchs, Jeffrey Meyer, Tyler Zemla, En Cheng, Priya Kumthekar, Katherine A Guthrie, Fel...> ;Clinical Cancer Research. 2023 May 11
Neoadjuvant Immunotherapy for Colorectal Cancer: Too Good to Be True?
Alan P Venook> ;JCO Oncology Practice. 2023 May 1
3 citations
Defining incidence and complications of fibrolamellar liver cancer through tiered computational analysis of clinical data.
Travis Zack, Kurt P Losert, Samantha M Maisel, Jennifer Wild, Amin Yaqubie, Michael Herman, Jennifer J Knox, Robert J Mayer, Alan P Venook, Atul Butte, Allison F O'Nei...> ;NPJ Precision Oncology. 2023 Mar 23
1 citations
Sexual function remains persistently low in women after treatment for colorectal cancer and anal squamous cell carcinoma.
Marissa B Savoie, Alan Paciorek, Katherine Van Loon, Mekhail Anwar, Chloe E Atreya, P Connor Johnson, Stacey A Kenfield, Angela Laffan, Anna O Levin, James F Smith, Da...> ;The Journal of Sexual Medicine. 2023 Mar 31
Quality of life among colorectal cancer survivors participating in a pilot randomized controlled trial of a web-based dietary intervention with text messages.
Lufan Wang, Crystal Langlais, Stacey A Kenfield, Katherine Van Loon, Angela Laffan, Chloe E Atreya, June M Chan, Li Zhang, Isabel E Allen, Christine Miaskowski, Yoshim...> ;Supportive Care in Cancer. 2023 Feb 10
3 citations
Dietary fat in relation to all-cause mortality and cancer progression and death among people with metastatic colorectal cancer: Data from CALGB 80405 (Alliance)/SWOG 8...
Van Blarigan, E., Ma, C., Ou, F., Bainter, T., Venook, A., Ng, K., Niedzwiecki, D., Giovannucci, E., Lenz, H., Polite, B., Hochster, H., Goldberg, R., Mayer, R., Blank...> ;International Journal of Cancer. 2023 Jan 15
Join now to see all

Journal Articles

Association of Coffee Intake with Survival in Patients with Advanced or Metastatic Colorectal Cancer
I-Wen Chang, Charles D Blanke, Alan P Venook, Richard M Goldberg, Jeffrey A Meyerhardt, Kimmie Ng, JAMA Oncology
Identification of a Genomic Region Between SLC29A1 and HSP90AB1 Associated with Risk of Bevacizumab-Induced Hypertension: CALGB 80405 (Alliance)
Hope S Rugo, Bryan P Schneider, Alan Venook, Clinical Cancer Research

Other

Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma
Alan Venook, MD, The New England Journal of Medicine
https://www.doximity.com/articles/e0e95f3b-5b2a-480c-ab49-4608e3eb9632
UpToDate, Wolters Kluwer Health - 2013-03-12
Nonsurgical local treatment strategies for colorectal cancer liver metastases
Venook AP
http://www.uptodate.com/contents/nonsurgical-local-treatment-strategies-for-colorectal-cancer-liver-
UpToDate, Wolters Kluwer Health - 2012-09-28

Press Mentions

CRC in Middle Age Linked to Morning Sickness Pill from 60s, 70sMarch 19th, 2023
No Survival Benefit with Upfront VEGF Inhibitors in Metastatic CRCFebruary 6th, 2023
UCSF Cancer Specialist Recognized with Luminary Award for Gastrointestinal CancersNovember 14th, 2022
Join now to see all

Grant Support

Data Safety MonitoringNational Cancer Institute2007–2011
C98-118-01: Sch58500 &Chemotherapy In Colorectal Cancer Metastatic To LiverNational Center For Research Resources2000–2002
Core--Clinical Research Support ServicesNational Cancer Institute1999–2002
Cancer And Leukemia Group BNational Cancer Institute1995–2002