AlexAnthonyRoherMD

PubMed

• Bapineuzumab alters a? composition: implications for the amyloid cascade hypothesis and anti-amyloid immunotherapy.
  Roher, A. E.,Cribbs, D. H.,Kim, R. C.,Maarouf, C. L.,Whiteside, C. M.,Kokjohn, T. A.,Daugs, I. D.,Head, E.,Liebsack, C.,Serrano, G.,Belden, C.,Sabbagh, M. N.,Beach, T. G.> ;PLoS ONE. 2013
• Subjects harboring presenilin familial Alzheimer's disease mutations exhibit diverse white matter biochemistry alterations.
  Roher, A. E.,Maarouf, C. L.,Malek-Ahmadi, M.,Wilson, J.,Kokjohn, T. A.,Daugs, I. D.,Whiteside, C. M.,Kalback, W. M.,Macias, M. P.,Jacobson, S. A.,Sabbagh, M. N.,Ghetti...> ;Am J Neurodegener Dis. 2013
• Biochemical assessment of precuneus and posterior cingulate gyrus in the context of brain aging and Alzheimer's disease.
  Maarouf, C. L.,Kokjohn, T. A.,Walker, D. G.,Whiteside, C. M.,Kalback, W. M.,Whetzel, A.,Sue, L. I.,Serrano, G.,Jacobson, S. A.,Sabbagh, M. N.,Reiman, E. M.,Beach, T. G...> ;PLoS ONE. 2014 Aug 29
• Cardiovascular system participation in Alzheimer's disease pathogenesis.
  Roher, A. E.> ;J. Intern. Med.. 2014 Sep 25
• Adipose and leptomeningeal arteriole endothelial dysfunction induced by β-amyloid peptide: A practical human model to study Alzheimer's disease vasculopathy.
  Truran, S.,Franco, D. A.,Roher, A. E.,Beach, T. G.,Burciu, C.,Serrano, G.,Maarouf, C. L.,Schwab, S.,Anderson, J.,Georges, J.,Reaven, P.,Migrino, R. Q.> ;J. Neurosci. Methods. 2014 Jul 09
• Alzheimer disease periventricular white matter lesions exhibit specific proteomic profile alterations.
  Castaño, E. M.,Maarouf, C. L.,Wu, T.,Leal, M. C.,Whiteside, C. M.,Lue, L. F.,Kokjohn, T. A.,Sabbagh, M. N.,Beach, T. G.,Roher, A. E.> ;Neurochem Int. 2013 Jan
• Neurochemical profile of dementia pugilistica.
  Kokjohn, T. A.,Maarouf, C. L.,Daugs, I. D.,Hunter, J. M.,Whiteside, C. M.,Malek-Ahmadi, M.,Rodriguez, E.,Kalback, W.,Jacobson, S. A.,Sabbagh, M. N.,Beach, T. G.,Roher,...> ;J Neurotrauma. 2013 Jun 1
• Chemical characterization of pro-inflammatory amyloid-beta peptides in human atherosclerotic lesions and platelets.
  Kokjohn, T. A., Van Vickle, G. D., Maarouf, C. L., Kalback, W. M., Hunter, J. M., Daugs, I. D., Luehrs, D. C., Lopez, J., Brune, D., Sue, L. I., Beach, T. G., Castaño,...> ;Biochim Biophys Acta. 2011 Nov
• Biochemical and morphological characterization of the AβPP/PS/tau triple transgenic mouse model and its relevance to sporadic Alzheimer's disease.
  Hunter, J. M., Bowers, W. J., Maarouf, C. L., Mastrangelo, M. A., Daugs, I. D., Kokjohn, T. A., Kalback, W. M., Luehrs, D. C., Valla, J., Beach, T. G., Roher, A. E.> ;J Alzheimers Dis. 2011
• Transcranial doppler ultrasound blood flow velocity and pulsatility index as systemic indicators for Alzheimer's disease.
  Roher, A. E., Garami, Z., Tyas, S. L., Maarouf, C. L., Kokjohn, T. A., Belohlavek, M., Vedders, L. J., Connor, D., Sabbagh, M. N., Beach, T. G., Emmerling, M. R.> ;Alzheimers Dement. 2011 Jul
• Intracranial atherosclerosis as a contributing factor to Alzheimer's disease dementia.
  Roher, A. E., Tyas, S. L., Maarouf, C. L., Daugs, I. D., Kokjohn, T. A., Emmerling, M. R., Garami, Z., Belohlavek, M., Sabbagh, M. N., Sue, L. I., Beach, T. G.> ;Alzheimers Dement. 2011 Jul
• Reduced clinical and postmortem measures of cardiac pathology in subjects with advanced Alzheimer's Disease.
  Beach, T. G., Maarouf, C. L., Brooks, R. G., Shirohi, S., Daugs, I. D., Sue, L. I., Sabbagh, M. N., Walker, D. G., Lue, L., Roher, A. E.> ;BMC Geriatr. 2011
• Neuropathology and amyloid-β spectrum in a bapineuzumab immunotherapy recipient.
  Roher, A. E., Maarouf, C. L., Daugs, I. D., Kokjohn, T. A., Hunter, J. M., Sabbagh, M. N., Beach, T. G.> ;J Alzheimers Dis. 2011
• Alzheimer's disease and non-demented high pathology control nonagenarians: comparing and contrasting the biochemistry of cognitively successful aging.
  Maarouf, C. L., Daugs, I. D., Kokjohn, T. A., Walker, D. G., Hunter, J. M., Kruchowsky, J. C., Woltjer, R., Kaye, J., Castaño, E. M., Sabbagh, M. N., Beach, T. G., Roh...> ;PLoS One. 2011
• The biochemical aftermath of anti-amyloid immunotherapy.
  Maarouf, C. L., Daugs, I. D., Kokjohn, T. A., Kalback, W. M., Patton, R. L., Luehrs, D. C., Masliah, E., Nicoll, J. A., Sabbagh, M. N., Beach, T. G., Castaño, E. M., R...> ;Mol Neurodegener. 2010
• 122 citations
  Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE ε4 allele, the major late-onset Alzheimer's susceptibility gene.
  Jon Valla, Roy Yaari, Andrew B. Wolf, Yael Kusne, Thomas G. Beach, Alex E. Roher, Jason J. Corneveaux, Matthew J. Huentelman, Richard J. Caselli, Eric M. Reiman> ;Journal of Alzheimer's Disease. 2010 Jan 1
• Patients with Alzheimer disease have altered transmitral flow: echocardiographic analysis of the vortex formation time.
  Belohlavek, M., Jiamsripong, P., Calleja, A. M., McMahon, E. M., Maarouf, C. L., Kokjohn, T. A., Chaffin, T. L., Vedders, L. J., Garami, Z., Beach, T. G., Sabbagh, M. ...> ;J Ultrasound Med. 2009 Nov 01
• Proteomics-derived cerebrospinal fluid markers of autopsy-confirmed Alzheimer''s disease.
  Roher, A. E., Maarouf, C. L., Sue, L. I., Hu, Y., Wilson, J., Beach, T. G.> ;Biomarkers. 2009 Nov 01
• Identifying early markers of Alzheimer's disease using quantitative multiplex proteomic immunoassay panels.
  Soares, H. D., Chen, Y., Sabbagh, M., Roher, A., Rohrer, A., Schrijvers, E., Breteler, M.> ;Ann N Y Acad Sci. 2009 Oct 01
• Commentary on "Alzheimer's disease drug development and the problem of the blood-brain barrier." Alzheimer's disease drugs: more than one barrier to breach.
  Roher, A. E., Kokjohn, T. A.> ;Alzheimers Dement. 2009 Sep 01
• Proteomic analysis of Alzheimer''s disease cerebrospinal fluid from neuropathologically diagnosed subjects.
  Maarouf, C. L., Andacht, T. M., Kokjohn, T. A., Castaño, E. M., Sue, L. I., Beach, T. G., Roher, A. E.> ;Curr Alzheimer Res. 2009 Aug 01
• Amyloid precursor protein transgenic mouse models and Alzheimer's disease: understanding the paradigms, limitations, and contributions.
  Kokjohn, T. A., Roher, A. E.> ;Alzheimers Dement. 2009 Jul 01
• Antibody responses, amyloid-beta peptide remnants and clinical effects of AN-1792 immunization in patients with AD in an interrupted trial.
  Kokjohn, T. A., Roher, A. E.> ;CNS Neurol Disord Drug Targets. 2009 Apr 01
• Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease.
  Roher, A. E., Esh, C. L., Kokjohn, T. A., Castaño, E. M., Van Vickle, G. D., Kalback, W. M., Patton, R. L., Luehrs, D. C., Daugs, I. D., Kuo, Y. M., Emmerling, M. R., ...> ;Alzheimers Dement. 2009 Jan 01
• Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations.
  Maarouf, C. L., Daugs, I. D., Spina, S., Vidal, R., Kokjohn, T. A., Patton, R. L., Kalback, W. M., Luehrs, D. C., Walker, D. G., Castaño, E. M., Beach, T. G., Ghetti, ...> ;Mol Neurodegener. 2008 Nov 22
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