AlexanderGeorgeBickMDPhD

PubMed

• Atrial Fibrillation and Clonal Hematopoiesis in TET2 and ASXL1.
  Seyedmohammad Saadatagah, Mohammadreza Naderian, Mesbah Uddin, Ozan Dikilitas, Abhishek Niroula, Art Schuermans, Elizabeth Selvin, Ron C Hoogeveen, Kunihiro Matsushita...> ;JAMA Cardiology. 2024 Apr 10
• Neutrophil-mediated innate immune resistance to bacterial pneumonia is dependent on Tet2 function.
  Candice Quin, Erica N DeJong, Elina K Cook, Yi Zhen Luo, Caitlyn Vlasschaert, Sanathan Sadh, Amy Jm McNaughton, Marco M Buttigieg, Jessica A Breznik, Allison E Kennedy...> ;The Journal of Clinical Investigation. 2024 Apr 4
• 1 citations
  Interoperability of phenome-wide multimorbidity patterns: a comparative study of two large-scale EHR systems.
  Nick Strayer, Tess Vessels, Karmel Choi, Siwei Zhang, Yajing Li, Brian Sharber, Ryan S Hsi, Cosmin A Bejan, Alexander G Bick, Justin M Balko, Douglas B Johnson, Lee E ...> ;Medrxiv. 2024 Mar 30
• 1 citations
  Clonal hematopoiesis of indeterminate potential is associated with acute kidney injury.
  Caitlyn Vlasschaert, Cassianne Robinson-Cohen, Jianchun Chen, Elvis Akwo, Alyssa C Parker, Samuel A Silver, Pavan K Bhatraju, Hannah Poisner, Shirong Cao, Ming Jiang, ...> ;Nature Medicine. 2024 Mar 1
• Clonal Hematopoiesis of Indeterminate Potential With Loss ofEnhances Risk for Atrial Fibrillation ThroughInflammasome Activation.
  Lin, A., Bapat, A., Xiao, L., Niroula, A., Ye, J., Wong, W., Agrawal, M., Farady, C., Boettcher, A., Hergott, C., McConkey, M., Flores-Bringas, P., Shkolnik, V., Bick,...> ;Circulation. 2024 Feb 15
• Radon Exposure, Clonal Hematopoiesis, and Stroke Susceptibility in the Women's Health Initiative.
  Huang, D. Y., Kurtis M Anthony, Jason M Collins, Shelly-Ann M Love, James D Stewart, Sophie F Buchheit, Rahul Gondalia, Gary G Schwartz, David Y Huang, Jaymie R Melike...> ;Neurology. 2024 Jan 23
• VEXAS-Defining UBA1 Somatic Variants in 245,368 Diverse Individuals in the NIH All Of Us Cohort.
  Robert W Corty, James Brogan, Kevin Byram, Jason Springer, Peter C Grayson, Alexander G Bick> ;Arthritis & Rheumatology. 2024 Jan 15
• Clonal Hematopoiesis Risk Score and All-Cause and Cardiovascular Mortality in Older Adults.
  Seyedmohammad Saadatagah, Md Mesbah Uddin, Lachelle D Weeks, Abhishek Niroula, Meng Ru, Koichi Takahashi, Lukasz Gondek, Bing Yu, Alexander G Bick, Benjamin L Ebert, E...> ;JAMA Network Open. 2024 Jan 2
• Clonal Hematopoiesis and Incident Heart Failure With Preserved Ejection Fraction.
  Schuermans, A., Raffield, L., Yu, B., Roberts, M., Kooperberg, C., Carson, A., Ballantyne, C., Manson, J., Whitsel, E., Eaton, C., Reiner, A., Honigberg, M., Desai, P....> ;JAMA Network Open. 2024 Jan 2
• Individual and Neighborhood-level Socioeconomic Status and Somatic Mutations Associated With Increased Risk of Cardiovascular Disease and Mortality: A Cross-Sectional ...
  Shelly-Ann M Love, Jason M Collins, Kurtis M Anthony, Sophie F Buchheit, Eboneé N Butler, Ganga S Bey, Rahul Gondalia, Kathleen M Hayden, Anthony S Zannas, Alexander G...> ;Women's Health Issues. 2023 Dec 6
• 2 citations
  Clonal Somatic Mutations in Chronic Lung Diseases Are Associated with Reduced Lung Function.
  Jeong H Yun, M A Wasay Khan, Auyon Ghosh, Brian D Hobbs, Peter J Castaldi, Craig P Hersh, Peter G Miller, Carlyne D Cool, Frank Sciurba, Lucas Barwick, Andrew H Limper...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Dec 1
• 5 citations
  Clonal haematopoiesis of indeterminate potential predicts incident cardiac arrhythmias.
  Art Schuermans, Caitlyn Vlasschaert, Victor Nauffal, So Mi Jemma Cho, Md Mesbah Uddin, Tetsushi Nakao, Abhishek Niroula, Marcus D R Klarqvist, Lachelle D Weeks, Amy E ...> ;European Heart Journal. 2024 Mar 7
• 3 citations
  Genetic Inhibition of APOL1 Pore-Forming Function Prevents APOL1-Mediated Kidney Disease.
  Wheless, L. E., Adriana M Hung, Victoria A Assimon, Hua-Chang Chen, Zhihong Yu, Caitlyn Vlasschaert, Jefferson L Triozzi, Helen Chan, Lee Wheless, Otis Wilson, Shailja...> ;Journal of the American Society of Nephrology. 2023 Nov 1
• 2 citations
  SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation.
  Chun-Wei Chen, Linda Zhang, Ravi Dutta, Abhishek Niroula, Peter G Miller, Christopher J Gibson, Alexander G Bick, Jaime M Reyes, Yi-Tang Lee, Ayala Tovy, Tianpeng Gu, ...> ;Cell Stem Cell. 2023 Nov 2
• 4 citations
  Clonal Hematopoiesis of Indeterminate Potential (CHIP) and Incident Type 2 Diabetes Risk.
  Deirdre K Tobias, Alisa K Manning, Jennifer Wessel, Sridharan Raghavan, Kenneth E Westerman, Alexander G Bick, Daniel Dicorpo, Eric A Whitsel, Jason Collins, Adolfo Co...> ;Diabetes Care. 2023 Nov 1
• 1 citations
  Infection risk associated with clonal hematopoiesis of indeterminate potential is partly mediated by hematologic cancer transformation in the UK Biobank.
  Caitlyn Vlasschaert, Elvis Akwo, Cassianne Robinson-Cohen, Elina K Cook, Matthew B Lanktree, Michael J Rauh, Alexander G Bick> ;Leukemia. 2023 Nov 1
• 1 citations
  Long-term longitudinal analysis of 4,187 participants reveals new insights into determinants of incident clonal hematopoiesis.
  Md Mesbah Uddin, Seyedmohammad Saadatagah, Abhishek Niroula, Bing Yu, Whitney Hornsby, Shriienidhie Ganesh, Kim Lannery, Art Shuermans, Michael C Honigberg, Alexander ...> ;Medrxiv. 2023 Sep 7
• 1 citations
  Genome-Wide Association Study of CKD Progression.
  Robinson-Cohen, C., Triozzi, J., Rowan, B., He, J., Chen, H., Zheng, N., Wei, W., Wilson, O., Hellwege, J., Tsao, P., Gaziano, J., Bick, A., Matheny, M., Chung, C., Li...> ;Journal of the American Society of Nephrology. 2023 Sep 1
• 2 citations
  PheMIME: An Interactive Web App and Knowledge Base for Phenome-Wide, Multi-Institutional Multimorbidity Analysis.
  Siwei Zhang, Nick Strayer, Tess Vessels, Karmel Choi, Geoffrey W Wang, Yajing Li, Cosmin A Bejan, Ryan S Hsi, Alexander G Bick, Digna R Velez Edwards, Michael R Savona...> ;Medrxiv. 2023 Jul 30
• 1 citations
  Age at Menopause, Leukocyte Telomere Length, and Coronary Artery Disease in Postmenopausal Women.
  Art Schuermans, Tetsushi Nakao, Md Mesbah Uddin, Whitney Hornsby, Shriie Ganesh, Aladdin H Shadyab, Simin Liu, Bernhard Haring, Chrisandra L Shufelt, Margaret A Taub, ...> ;Circulation Research. 2023 Aug 18
• 4 citations
  Clonal Hematopoiesis in Young Women Treated for Breast Cancer.
  Christopher J Gibson, Geoffrey Fell, Tal Sella, Adam S Sperling, Craig Snow, Shoshana M Rosenberg, Greg Kirkner, Ashka Patel, Deborah Dillon, Alexander G Bick, Donna N...> ;Clinical Cancer Research. 2023 Jul 5
• 6 citations
  Diversity and Scale: Genetic Architecture of 2,068 Traits in the VA Million Veteran Program.
  Anurag Verma, Jennifer E Huffman, Alex Rodriguez, Mitchell Conery, Molei Liu, Yuk-Lam Ho, Youngdae Kim, David A Heise, Lindsay Guare, Vidul Ayakulangara Panickan, Hele...> ;Medrxiv. 2023 Jun 29
• 2 citations
  Birth Weight Is Associated With Clonal Hematopoiesis of Indeterminate Potential and Cardiovascular Outcomes in Adulthood.
  Art Schuermans, Tetsushi Nakao, Yunfeng Ruan, Satoshi Koyama, Zhi Yu, Md Mesbah Uddin, Sara Haidermota, Whitney Hornsby, Adam J Lewandowski, Alexander G Bick, Abhishek...> ;Journal of the American Heart Association. 2023 Jul 4
• 20 citations
  Clonal hematopoiesis is associated with protection from Alzheimer's disease.
  Hind Bouzid, Julia A Belk, Max Jan, Yanyan Qi, Chloé Sarnowski, Sara Wirth, Lisa Ma, Matthew R Chrostek, Herra Ahmad, Daniel Nachun, Winnie Yao, , Alexa Beiser, Alexan...> ;Nature Medicine. 2023 Jul 1
• 1 citations
  Association of Clonal Hematopoiesis of Indeterminate Potential with Incident Heart Failure with Preserved Ejection Fraction.
  Alex P Reiner, Mary B Roberts, Michael C Honigberg, Charles Kooperberg, Pinkal Desai, Alexander G Bick, Pradeep Natarajan, JoAnn E Manson, Eric A Whitsel, Charles B Eaton> ;Medrxiv. 2023 Jun 10
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Journal Articles

• DNA Sequence Variation in ACVR1C Encoding the Activin-Receptor like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes  
  Derek Klarin, Pradeep Natarajan, Ruth McPherson, Sekar Kathiresan, Krishna Aragam, Alexander Bick, Diabetes Care