AlexanderDimitriosColevasMD

Oncology • Stanford, CA

Head & Neck Cancer, Hematologic Oncology

Professor, Medicine - Oncology, Stanford University Medical Center

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Office
875 blake wilbur drive
Stanford, CA 94305
Phone+1 650-724-9707
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Education & Training

Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 1993 - 1996
Johns Hopkins UniversityResidency, Internal Medicine, 1989 - 1992
Johns Hopkins University School of MedicineClass of 1989

Certifications & Licensure

CA State Medical License 2007 - 2024
MD State Medical License 1991 - 2008
MA State Medical License 1993 - 2001
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011-2013

Clinical Trials

Phase 2 Sequential and Concurrent Chemoradiation for Advanced Nasopharyngeal Carcinoma (NPC) Start of enrollment: 2008 Dec 10
Completed
Phase 2
Capecitabine in Treating Patients With Advanced or Recurrent Squamous Cell Carcinoma of the Skin Start of enrollment: 2013 Mar 01
Terminated
Phase 2
Dabrafenib and Trametinib in Treating Patients With BRAF Mutated Ameloblastoma Start of enrollment: 2017 Jul 17
Completed
Phase 2
Docetaxel, Cisplatin, and Cetuximab (TPC) in Palliative Treatment of Patients With Squamous Cell Carcinoma of the Head and Neck (SCCHN) Start of enrollment: 2011 Oct 01
Completed
Phase 2
Clinical Trial of a Novel Small Molecule EBNA1 Inhibitor, VK 2019, in Patients With Epstein Barr Virus (EBV)-Positive Nasopharyngeal Cancer (NPC) and Other Epstein-Barr Virus (EBV)-Associated Cancers, With Pharmacokinetic and Pharmacodynamic Correlative Studies Start of enrollment: 2022 Jan 25
Recruiting
Phase 2
Safety and Efficacy of Repeat Administration of Ad/PNP and Fludarabine Phosphate in Patients With Local Head/Neck Cancer Start of enrollment: 2019 Feb 11
Recruiting
Phase 1, Phase 2
Roles: Contact, Principal Investigator
Phase 1/2a Study of VK-2019 in Patients With Epstein-Barr Virus (EBV)-Positive Nasopharyngeal Carcinoma (NPC) Start of enrollment: 2019 Apr 04
Terminated
Phase 1, Phase 2
Study to Evaluate Immunological Response to PD-1 Inhibition in Squamous Cell Carcinoma of the Head and Neck (SCCHN) Start of enrollment: 2017 May 01
Completed
Phase 1
Combination Chemotherapy in Treating Patients With Stage IIB, Stage III, or Stage IV Cancer of the Nasopharynx Start of enrollment: 1999 Aug 01
Unknown status
Phase 2
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Publications & Presentations

PubMed

7 citations
Generating in silico CODEX from a small set of immunofluorescence markers.
Eric Wu, Alexandro E Trevino, Zhenqin Wu, Kyle Swanson, Honesty J Kim, H Blaize D'Angio, Ryan Preska, Aaron E Chiou, Gregory W Charville, Piero Dalerba, Umamaheswar Du...> ;PNAS Nexus. 2023 Jun 1
2 citations
Immunotherapy for keratinocyte cancers. Part I: Immune-related epidemiology, risk factors, pathogenesis, and immunotherapy management of keratinocyte cancers.
Romy A Neuner, Jinwoo Lee, Kerri E Rieger, Caroline Park, Alexander D Colevas, Anne Lynn S Chang> ;Journal of the American Academy of Dermatology. 2023 Jun 1
1 citations
In search for optimal induction chemotherapy for advanced nasopharyngeal cancer: Standard dosing of Docetaxel, Platinum, and 5-Fluorouracil (TPF) followed by chemoradi...
Michelle Jun, Harlan Pinto, Quynh-Thu Le, Andrew Quon, Wendy Hara, Jessie Coty, Alex McMillan, Rong Lu, Elzbieta Winters, Ruth Lira, A Dimitrios Colevas> ;Plos One. 2023 Jan 1
3 citations
Safety of Nivolumab Added to Chemoradiation Therapy Platforms for Intermediate and High-Risk Locoregionally Advanced Head and Neck Squamous Cell Carcinoma: RTOG Founda...
Maura L Gillison, Robert L Ferris, Jonathan Harris, A Dimitrios Colevas, Loren K Mell, Christina Kong, Richard C Jordan, Kevin L Moore, Minh-Tam Truong, Claudia Kirsch...> ;International Journal of Radiation Oncology, Biology, Physics. 2023 Mar 15
2 citations
89Zr-panitumumab Combined With 18F-FDG PET Improves Detection and Staging of Head and Neck Squamous Cell Carcinoma.
Yu-Jin Lee, Nynke S van den Berg, Heying Duan, E Carmen Azevedo, Valentina Ferri, Marisa Hom, Roan C Raymundo, Alex Valencia, Jessa Castillo, Bin Shen, Quan Zhou, Laur...> ;Clinical Cancer Research. 2022 Oct 14
5 citations
Posttreatment FDG-PET/CT Hopkins criteria predict locoregional recurrence after definitive radiotherapy for oropharyngeal squamous cell carcinoma.
Jacob A Miller, Farshad Moradi, Vandana Sundaram, Rachel Liang, Carrie Zhang, Ngan Kim Nguyen, Faisal Akhtar, Yuhan Liu, Yulan Ren, Nima Harandi, Yingjie Weng, Erqi L ...> ;Head & Neck. 2022 Nov 1
4 citations
A phase II study of tarloxotinib (a hypoxia activated prodrug of a pan-erb tyrosine kinase inhibitor) in patients with recurrent or metastatic squamous cell carcinoma ...
Luke S McLean, Tessa A Morris, Ann Gramza, Stephen Liu, Saad A Khan, A Dimitrios Colevas, Tillman Pearce, Danny Rischin> ;Investigational New Drugs. 2022 Aug 1
2 citations
HPV DNA as a Biomarker in Oropharyngeal Cancer: A Step in the Right Direction.
A Dimitrios Colevas> ;Clinical Cancer Research. 2022 Oct 3
17 citations
Long-term Outcomes with Nivolumab as First-line Treatment in Recurrent or Metastatic Head and Neck Cancer: Subgroup Analysis of CheckMate 141.
Maura L Gillison, George Blumenschein, Jerome Fayette, Joel Guigay, A Dimitrios Colevas, Lisa Licitra, Kevin J Harrington, Stefan Kasper, Everett E Vokes, Caroline Eve...> ;The Oncologist. 2022 Mar 4
234 citations
NCCN Guidelines® Insights: Head and Neck Cancers, Version 1.2022.
Jimmy J Caudell, Maura L Gillison, Ellie Maghami, Sharon Spencer, David G Pfister, Douglas Adkins, Andrew C Birkeland, David M Brizel, Paul M Busse, Anthony J Cmelak, ...> ;Journal of the National Comprehensive Cancer Network. 2022 Mar 1
2 citations
Skull base osteomyelitis in patients with head and neck cancer: Diagnosis, management, and outcomes in a case series of 23 patients.
Mary M Czech, Peter H Hwang, Alexander Dimitrios Colevas, Nancy Fischbein, Dora Y Ho> ;Laryngoscope Investigative Otolaryngology. 2022 Feb 1
2 citations
Metastatic Parotid Gland Carcinoma With ERBB2 Amplification With Complete Response to Fam-Trastuzumab Deruxtecan.
Navika D Shukla, Ryan S Chiang, Alexander D Colevas> ;Journal of the National Comprehensive Cancer Network. 2022 Feb 1
1 citations
Genome Sequencing and Apoptotic Markers to Assess Treatment Response of Lacrimal Gland Adenoid Cystic Carcinoma to Intra-Arterial Cytoreductive Chemotherapy.
Michael D Yu, Clara J. Men, Huy M. Do, A Dimitrios Colevas, Jonathan H. Lin, Peter R. Egbert, David T. Tse, Andrea L. Kossler> ;Ophthalmic Plastic and Reconstructive Surgery. 2021 Nov 16
10 citations
Do Steroids Matter? A Retrospective Review of Premedication for Taxane Chemotherapy and Hypersensitivity Reactions.
Olivia M Lansinger, Savanna Biedermann, Zihuai He, A. Dimitrios Colevas> ;Journal of Clinical Oncology. 2021 Aug 6
2 citations
Association Between Immunosuppression and Outcomes in Oral Cavity Squamous Cell Carcinoma.
Julia Chang, John B. Sunwoo, J.L. Shah, Wendy Hara, Jison Hong, A. Dimitrios Colevas, Vasu Divi> ;Otolaryngology--Head and Neck Surgery. 2021 May 1
11 citations
Prolongation of definitive head and neck cancer radiotherapy: Survival impact and predisposing factors.
Michael Xiang, Michael F. Gensheimer, Erqi L. Pollom, Floyd Christopher Holsinger, A.D. Colevas, Quynh-Thu Le, Beth M. Beadle> ;Radiotherapy and Oncology. 2021 Mar 1
51 citations
Myocarditis Surveillance with High-Sensitivity Troponin I During Cancer Treatment with Immune Checkpoint Inhibitors.
Sarah Waliany, Joel W. Neal, Sunil Reddy, Heather A. Wakelee, Sumit A. Shah, Sandy Srinivas, Sukhmani K. Padda, Alice C. Fan, A. Dimitrios Colevas, Sean M. Wu, Ronald ...> ;JACC. Cardiooncology. 2021 Mar 1
18 citations
Intraoperative Fluorescence-Guided Surgery in Head and Neck Squamous Cell Carcinoma
Yu-Jin Lee, Giri Krishnan, Naoki Nishio, Nynke S. van den Berg, Guolan Lu, Brock A. Martin, Stan van Keulen, A.D. Colevas, Shrey Kapoor, Jonathan T. C. Liu, Eben L. Ro...> ;The Laryngoscope. 2021 Mar 1
4 citations
Safety and Stability of Antibody-Dye Conjugate in Optical Molecular Imaging.
Jacqueline Pei, Georgina Juniper, Nynke S. van den Berg, Naoki Nisho, Trevor Broadt, Anthony R. Welch, Grace Yi, Roan C Raymundo, Stefania U. Chirita, Guolan Lu, Giri ...> ;Molecular Imaging and Biology. 2021 Feb 1
28 citations
Unambiguous advanced radiologic extranodal extension determined by MRI predicts worse outcomes in nasopharyngeal carcinoma: Potential improvement for future editions o...
Yan Ping Mao, Shunxin Wang, William Lydiatt, Jatin P. Shah, A. Dimitrios Colevas, Anne W.M. Lee, Brian O'Sullivan, Rui Guo, Wei-Jie Luo, Yu Pei Chen, Li Tian, Ling-Lon...> ;Radiotherapy and Oncology. 2021 Jan 28
134 citations
Chemotherapy in Combination With Radiotherapy for Definitive-Intent Treatment of Stage II-IVA Nasopharyngeal Carcinoma: CSCO and ASCO Guideline
Yu Pei Chen, Nofisat Ismaila, Melvin L.K. Chua, A. Dimitrios Colevas, Robert I. Haddad, Shao Hui Huang, Joseph Wee, Alexander C Whitley, Jun-Lin Yi, Sue S. Yom, Anthon...> ;Journal of Clinical Oncology. 2021 Jan 6
3 citations
Postoperative Observation Versus Radiotherapy for Pathologic N1 Oral Cavity Squamous Cell Carcinoma
Michael Xiang, Floyd Christopher Holsinger, Michael F. Gensheimer, Vasu Divi, Erqi L. Pollom, A.D. Colevas, Quynh-Thu Le, Beth M. Beadle> ;American Journal of Clinical Oncology. 2021 Jan 6
19 citations
Metastatic and sentinel lymph node mapping using intravenously delivered Panitumumab-IRDye800CW.
Giri Krishnan, Nynke S. van den Berg, Naoki Nishio, Georgina Juniper, Jaqueline Pei, Quan Zhou, Guolan Lu, Yu-Jin Lee, Kimberly Ramos, Andrei Iagaru, Fred M. Baik, A.D...> ;Theranostics. 2021 Jan 1
47 citations
Co-administered antibody improves penetration of antibody-dye conjugate into human cancers with implications for antibody-drug conjugates.
Guolan Lu, Naoki Nishio, Nynke S. van den Berg, Brock A. Martin, Shayan Fakurnejad, Stan van Keulen, A.D. Colevas, Greg M. Thurber, Eben L. Rosenthal> ;Nature Communications. 2020 Nov 9
2 citations
Metastatic cutaneous squamous cell carcinoma responsive to cemiplimab in a patient with multiple myeloma
Nareh Valerie Marukian, John Q. Lin, A. Dimitrios Colevas, Steven Coutre, Anne Lynn S. Chang> ;JAAD Case Reports. 2020 Jul 8
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Journal Articles

Identification and Validation of Novel Microenvironment-Based Immune Molecular Subgroups of Head and Neck Squamous Cell Carcinoma: Implications for Immunotherapy
J Ma, D N Hayes, A Dimitrios Colevas, N Lee, Annals of Oncology