AlexanderGrinbergMD

PubMed

• 33 citations
  Two RNase H2 Mutants with Differential rNMP Processing Activity Reveal a Threshold of Ribonucleotide Tolerance for Embryonic Development.
  Ryo Uehara, Susana M. Cerritelli, Naushaba Hasin, Kiran Sakhuja, Mariya London, Jaime Iranzo, Hyongi Chon, Alexander Grinberg, Robert J. Crouch> ;Cell Reports. 2018 Oct 30
• 89 citations
  Genetic ablation of Pannexin1 protects retinal neurons from ischemic injury.
  Galina Dvoriantchikova, Dmitry Ivanov, David J. Barakat, Alexander Grinberg, Rong-Kun Wen, Vladlen Z. Slepak, Valery I. Shestopalov> ;Plos One. 2012 Feb 23
• 183 citations
  CCR6 is required for IL-23–induced psoriasis-like inflammation in mice
  Michael N. Hedrick, Anke S. Lonsdorf, Aiko Konno Shirakawa, Chyi-Chia Richard Lee, Fang Liao, Satya P. Singh, Hongwei H. Zhang, Alexander Grinberg, Paul E. Love, Samue...> ;The Journal of Clinical Investigation. 2009 Aug 3
• 50 citations
  Development and characterization of a hypomorphic Smith–Lemli–Opitz syndrome mouse model and efficacy of simvastatin therapy
  Lina S. Correa-Cerro, Christopher A. Wassif, Lisa E. Kratz, Georgina F. Miller, Jeeva Munasinghe, Alexander Grinberg, Steven J. Fliesler, Forbes D. Porter> ;Human Molecular Genetics. 2006 Mar 15
• 118 citations
  A Functional Floxed Allele of Pkd1 that Can Be Conditionally Inactivated In Vivo
  Klaus Piontek, David L. Huso, Alexander Grinberg, Lijuan Liu, Djahida Bedja, Haidan Zhao, Kathleen L. Gabrielson, Feng Qian, Changlin Mei, Heiner Westphal, Gregory G. ...> ;Journal of the American Society of Nephrology. 2004 Dec 1
• 40 citations
  Targeted point mutagenesis of mouse Kcnq1: phenotypic analysis of mice with point mutations that cause Romano-Ward syndrome in humans
  Mathew C. Casimiro, Bjoern C. Knollmann, Ebenezer N. Yamoah, Liping Nie, Jay C. Vary, Syevda G. Sirenko, Anne E. Greene, Alexander Grinberg, Sing Ping Huang, Steven N....> ;Genomics. 2004 Sep 1
• 118 citations
  Lathosterolosis: an inborn error of human and murine cholesterol synthesis due to lathosterol 5-desaturase deficiency
  Patrycja A. Krakowiak, Christopher A. Wassif, Lisa E. Kratz, Diana Cozma, Martina Kovářová, Ginny Harris, Alexander Grinberg, Yinzi Yang, Alasdair G. W. Hunter, Maria ...> ;Human Molecular Genetics. 2003 Jul 1
• 128 citations
  Biochemical, phenotypic and neurophysiological characterization of a genetic mouse model of RSH/Smith–Lemli–Opitz syndrome
  Christopher A. Wassif, Pinjun Zhu, Lisa E. Kratz, Patrycja A. Krakowiak, Kevin P. Battaile, Forrest F. Weight, Alexander Grinberg, Robert D. Steiner, Ngozi A. Nwokoro,...> ;Human Molecular Genetics. 2001 Mar 15
• 77 citations
  Generation and phenotype of mice harboring a nonsense mutation in the V2 vasopressin receptor gene.
  June Yun, Torsten Schöneberg, Jie Liu, Angela Schulz, Carolyn A. Ecelbarger, Dominique Promeneur, Søren Nielsen, Hui Sheng, Alexander Grinberg, Chu-Xia Deng, Jürgen Wess> ;The Journal of Clinical Investigation. 2000 Dec 1
• 86 citations
  Glial cell line-derived neurotrophic factor receptor α1 availability regulates glial cell line-derived neurotrophic factor signaling: evidence from mice carrying one o...
  Andreas Tomac, Alexander Grinberg, Sing-Ping Huang, Christopher A. Nosrat, Yumei Wang, Cesario V. Borlongan, Shinn Zong Lin, Yung-Hsiao Chiang, Lars Olson, Heiner West...> ;Neuroscience. 1999 Dec 1
• 24 citations
  Increased blood–brain barrier permeability in LP-BM5 infected mice is mediated by neuroexcitatory mechanisms
  Yelena Kustova, Alexander Grinberg, Anthony S. Basile> ;Brain Research. 1999 Aug 21
• 136 citations
  Functional overlap between murine Inpp5b and Ocrl1 may explain why deficiency of the murine ortholog for OCRL1 does not cause Lowe syndrome in mice.
  Pasi A. Jänne, Sharon F. Suchy, David J. Bernard, Michael MacDonald, Jacqueline N. Crawley, Alexander Grinberg, Anthony Wynshaw-Boris, Heiner Westphal, Robert L. Nussbaum> ;The Journal of Clinical Investigation. 1998 May 15
• 74 citations
  Mouse model of GM2 activator deficiency manifests cerebellar pathology and motor impairment
  Yujing Liu, Alexander Hoffmann, Alexander Grinberg, Heiner Westphal, Michael P. McDonald, Katherine M. Miller, Jacqueline N. Crawley, Konrad Sandhoff, Kinuko Suzuki, R...> ;Proceedings of the National Academy of Sciences of the United States of America. 1997 Jul 22
• 343 citations
  Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism
  Kazunori Sango, Shoji Yamanaka, Alexander Hoffmann, Yasuharu Okuda, Alexander Grinberg, Heiner Westphal, Michael P. McDonald, Jacqueline N. Crawley, Konrad Sandhoff, K...> ;Nature Genetics. 1995 Oct 1
• 814 citations
  Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.
  Xiqing Cao, Elizabeth W. Shores, Jane Hu-Li, Miriam R. Anver, Brian L. Kelsail, Sarah M. Russell, John Drago, Masayuki Noguchi, Alexander Grinberg, Eda T. Bloom, Willi...> ;Immunity. 1995 Mar 1
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