AlexanderR.ShikhmanMDPhD FACR

PubMed

• 44 citations
  Analysis of Autoantibodies to 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase Using Different Technologies
  Lucile Musset, Makoto Miyara, Olivier Benveniste, Jean Luc Charuel, Alexander Shikhman, Olivier Boyer, Richard Fowler, Andrew L. Mammen, Joe Phillips, Michael Mahler> ;Journal of Immunology Research. 2014 Mar 5
• 32 citations
  Differential metabolic effects of glucosamine and N-acetylglucosamine in human articular chondrocytes
  Alexander R. Shikhman, Diana C. Brinson, Jean Valbracht, Martin Lotz> ;Osteoarthritis and Cartilage. 2009 Aug 1
• 67 citations
  Chondroprotective activity of N -acetylglucosamine in rabbits with experimental osteoarthritis
  Alexander R. Shikhman, David Amiel, Darryl D. D'Lima, S-B Hwang, Changyong Hu, A Xu, Sanshiro Hashimoto, Kohei Kobayashi, Takahisa Sasho, Martin Lotz> ;Annals of the Rheumatic Diseases. 2005 Jan 1
• 44 citations
  Synthesis and High-Throughput Screening of N-Acetyl-β-hexosaminidase Inhibitor Libraries Targeting Osteoarthritis
  Junjie Liu, Mehdi M. D. Numa, Haitian Liu, Shi-Jung Huang, Pamela Sears, Alexander R. Shikhman, Chi-Huey Wong> ;The Journal of Organic Chemistry. 2004 Aug 7
• 34 citations
  Distinct pathways regulate facilitated glucose transport in human articular chondrocytes during anabolic and catabolic responses
  Alexander R. Shikhman, Diana C. Brinson, Martin Lotz> ;American Journal of Physiology. Endocrinology and Metabolism. 2004 Jun 1
• 58 citations
  Role of nitric oxide, reactive oxygen species, and p38 MAP kinase in the regulation of human chondrocyte apoptosis.
  Klaus Kühn, Alexander R. Shikhman, Martin Lotz> ;Journal of Cellular Physiology. 2003 Dec 1
• 106 citations
  Cytokine Regulation of Facilitated Glucose Transport in Human Articular Chondrocytes
  Alexander R. Shikhman, Diana C. Brinson, Jean Valbracht, Martin Lotz> ;Journal of Immunology. 2001 Dec 15
• 52 citations
  Hexosaminidase inhibitors as new drug candidates for the therapy of osteoarthritis
  Junjie Liu, Alexander R. Shikhman, Martin Lotz, Chi-Huey Wong> ;Chemistry & Biology. 2001 Jul 1
• 143 citations
  N-Acetylglucosamine Prevents IL-1β-Mediated Activation of Human Chondrocytes
  Alexander R. Shikhman, Klaus Kühn, Nada Alaaeddine, Martin Lotz> ;Journal of Immunology. 2001 Apr 15
• 48 citations
  Profile of glycosaminoglycan-degrading glycosidases and glycoside sulfatases secreted by human articular chondrocytes in homeostasis and inflammation.
  Alexander R. Shikhman, Diana C. Brinson, Martin Lotz> ;Arthritis and Rheumatism. 2000 Jun 1
• 60 citations
  Cytokeratin peptide SFGSGFGGGY mimics N-acetyl-beta-D-glucosamine in reaction with antibodies and lectins, and induces in vivo anti-carbohydrate antibody response.
  Alexander R. Shikhman, Neil S. Greenspan, Madeleine W. Cunningham> ;Journal of Immunology. 1994 Dec 15
• 60 citations
  Immunological mimicry between N-acetyl-beta-D-glucosamine and cytokeratin peptides. Evidence for a microbially driven anti-keratin antibody response.
  Alexander R. Shikhman, M W Cunningham> ;Journal of Immunology. 1994 May 1
• 62 citations
  A subset of mouse monoclonal antibodies cross-reactive with cytoskeletal proteins and group A streptococcal M proteins recognizes N-acetyl-beta-D-glucosamine.
  Alexander R. Shikhman, Neil S. Greenspan, Madeleine W. Cunningham> ;Journal of Immunology. 1993 Oct 1
• The osteoprotegerin/receptor activator of nuclear factor kappaB/receptor activator of nuclear factor kappaB ligand system in cartilage.
  Komuro, H., Olee, T., Kühn, K., Quach, J., Brinson, D. C., Shikhman, A., Valbracht, J., Creighton-Achermann, L., Lotz, M.> ;Arthritis Rheum. 2001 Dec
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