AlexanderNStarodubMD

PubMed

• 3 citations
  Phase Ib Study of the BET Inhibitor GS-5829 as Monotherapy and Combined with Enzalutamide in Patients with Metastatic Castration-Resistant Prostate Cancer.
  Rahul Aggarwal, Alexander N Starodub, Brian D Koh, Guan Xing, Andrew J Armstrong, Michael A Carducci> ;Clinical Cancer Research. 2022 Sep 15
• 20 citations
  Safety, tolerability and efficacy of agonist anti-CD27 antibody (varlilumab) administered in combination with anti-PD-1 (nivolumab) in advanced solid tumors.
  Rachel E Sanborn, Michael J Pishvaian, Margaret K Callahan, Amy Weise, Branimir I Sikic, Osama Rahma, Daniel C Cho, Naiyer A Rizvi, Mario Sznol, Jose Lutzky, Julie E B...> ;Journal for Immunotherapy of Cancer. 2022 Aug 1
• 26 citations
  Phase III Study to Evaluate Efficacy and Safety of Andecaliximab With mFOLFOX6 as First-Line Treatment in Patients With Advanced Gastric or GEJ Adenocarcinoma (GAMMA-1)
  Manish A. Shah, György Bodoky, Alexander Starodub, David Cunningham, Desmond Yip, Zev A. Wainberg, Johanna C. Bendell, Dung Thai, Joyce He, Pankaj Bhargava, Jaffer A. ...> ;Journal of Clinical Oncology. 2021 Feb 12
• 2 citations
  Effects of Rovalpituzumab Tesirine on Ventricular Repolarization in Patients With Small-Cell Lung Cancer
  Jonathan W. Goldman, Minal A. Barve, Jyoti D. Patel, Antoinette J. Wozniak, Afshin Dowlati, Alexander Starodub, Taofeek K. Owonikoko, William Jeffery Edenfield, Scott ...> ;Clinical and Translational Science. 2021 Mar 1
• 17 citations
  Safety and Efficacy of Andecaliximab (GS-5745) Plus Gemcitabine and Nab-Paclitaxel in Patients with Advanced Pancreatic Adenocarcinoma: Results from a Phase I Study.
  Johanna C. Bendell, Sunil Sharma, Manish R. Patel, Kevin S Windsor, Zev A. Wainberg, Michael S. Gordon, Jordan Berlin, Carrie Baker Brachmann, Marianna Zavodovskaya, J...> ;The Oncologist. 2020 Nov 1
• 29 citations
  Phase 1 dose-escalation study of momelotinib, a Janus kinase 1/2 inhibitor, combined with gemcitabine and nab-paclitaxel in patients with previously untreated metastat...
  Kimmie Ng, Andrew Eugene Hendifar, Alexander Starodub, Jorge Chaves, Yingsi Yang, Brian Koh, David A. Barbie, William C. Hahn, Charles S. Fuchs> ;Investigational New Drugs. 2019 Feb 1
• 62 citations
  Andecaliximab/GS-5745 Alone and Combined with mFOLFOX6 in Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Results from a Phase I Study
  Manish A. Shah, Alexander Starodub, Sunil Sharma, Jordan Berlin, Manish R. Patel, Zev A. Wainberg, Jorge Chaves, Michael S. Gordon, Kevin S Windsor, Carrie Baker Brach...> ;Clinical Cancer Research. 2018 Aug 15
• 89 citations
  Phase 2 Trial of Gemcitabine, Cisplatin, plus Ipilimumab in Patients with Metastatic Urothelial Cancer and Impact of DNA Damage Response Gene Mutations on Outcomes
  Matthew D. Galsky, Huan Wang, Noah M. Hahn, Przemyslaw Twardowski, Sumanta K. Pal, Costantine Albany, Mark D. Fleming, Alexander Starodub, Ralph J. Hauke, Menggang Yu,...> ;European Urology. 2017 Dec 13
• 95 citations
  Therapy of Small Cell Lung Cancer (SCLC) with a Topoisomerase-I-inhibiting Antibody-Drug Conjugate (ADC) Targeting Trop-2, Sacituzumab Govitecan.
  Jhanelle E. Gray, Rebecca S. Heist, Alexander Starodub, D. Ross Camidge, Ebenezer A. Kio, Gregory A. Masters, W. Thomas Purcell, Michael J. Guarino, Jamal Misleh, Char...> ;Clinical Cancer Research. 2017 Oct 1
• 55 citations
  Phase I/II Trial of Labetuzumab Govitecan (Anti-CEACAM5/SN-38 Antibody-Drug Conjugate) in Patients With Refractory or Relapsing Metastatic Colorectal Cancer
  Efrat Dotan, Steven J. Cohen, Alexander Starodub, Christopher H. Lieu, Wells A. Messersmith, Pamela S. Simpson, Michael J. Guarino, John L. Marshall, Richard M Goldber...> ;Journal of Clinical Oncology. 2017 Aug 17
• LBA-003Phase 1b/II study of cancer stemness inhibitor napabucasin in combination with FOLFIRI +/- bevacizumab (bev) in metastatic colorectal cancer (mCRC) patients (pts).
  Bendell, J.,Hubbard, J.,O'Neil, B. H.,Jonker, D.,Starodub, A.,Peyton, J.,Pitot, H.,Halfdanarson, T.,Nadeau, B.,Zubkus, J.,Adesunloye, B.,Edenfield, J.,Li, Y. Z.,Li, W....> ;Ann. Oncol.. 2018 Jul 28
• 130 citations
  Sacituzumab govitecan (IMMU-132), an anti-Trop-2-SN-38 antibody-drug conjugate for the treatment of diverse epithelial cancers: Safety and pharmacokinetics
  Allyson J. Ocean, Alexander Starodub, Aditya Bardia, Linda T. Vahdat, Steven J. Isakoff, Michael J. Guarino, Wells A. Messersmith, Vincent J. Picozzi, Ingrid A. Mayer,...> ;Cancer. 2017 Oct 1
• 101 citations
  Therapy of Advanced Non-Small-Cell Lung Cancer With an SN-38-Anti-Trop-2 Drug Conjugate, Sacituzumab Govitecan
  Rebecca S. Heist, Michael J. Guarino, Gregory A. Masters, W. Thomas Purcell, Alexander Starodub, Leora Horn, Ronald J. Scheff, Aditya Bardia, Wells A. Messersmith, Jor...> ;Journal of Clinical Oncology. 2017 May 26
• 182 citations
  Efficacy and Safety of Anti-Trop-2 Antibody Drug Conjugate Sacituzumab Govitecan (IMMU-132) in Heavily Pretreated Patients With Metastatic Triple-Negative Breast Cancer.
  Aditya Bardia, Ingrid A. Mayer, Jennifer R. Diamond, Rebecca L. Moroose, Steven J. Isakoff, Alexander Starodub, Nikita C. Shah, Joyce O'Shaughnessy, Kevin Kalinsky, Mi...> ;Journal of Clinical Oncology. 2017 Mar 14
• 19 citations
  90Y-clivatuzumab tetraxetan with or without low-dose gemcitabine: A phase Ib study in patients with metastatic pancreatic cancer after two or more prior therapies
  , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;European Journal of Cancer. 2015 Sep 1
• 23 citations
  A Phase I/II Trial of BNC105P with Everolimus in Metastatic Renal Cell Carcinoma
  Sumanta K. Pal, Arun Azad, Shailender Bhatia, Harry A. Drabkin, Brian A. Costello, John Sarantopoulos, Ravindran Kanesvaran, Richard C. Lauer, Alexander Starodub, Ralp...> ;Clinical Cancer Research. 2015 Aug 1
• 177 citations
  First-in-Human Trial of a Novel Anti-Trop-2 Antibody-SN-38 Conjugate, Sacituzumab Govitecan, for the Treatment of Diverse Metastatic Solid Tumors.
  Alexander Starodub, Allyson J. Ocean, Manish A. Shah, Michael J. Guarino, Vincent J. Picozzi, Linda T. Vahdat, Sajeve Samuel Thomas, Serengulam V. Govindan, Pius Malia...> ;Clinical Cancer Research. 2015 May 5
• 5 citations
  Phase I study of capecitabine, oxaliplatin, bevacizumab, and everolimus in advanced solid tumors
  Fatima A. Rangwala, Johanna C. Bendell, Mark Kozloff, Christy Arrowood, Andrew Dellinger, Jennifer Meadows, Sandra Tourt-Uhlig, Jennifer Murphy, Kellen L. Meadows, Aij...> ;Investigational New Drugs. 2014 Apr 9
• 16 citations
  Phase I study of dasatinib in combination with capecitabine, oxaliplatin and bevacizumab followed by an expanded cohort in previously untreated metastatic colorectal c...
  John H. Strickler, Shannon J. McCall, Andrew B. Nixon, John C. Brady, Herbert Pang, Christel Rushing, Allen Lee Cohn, Alexander Starodub, Christy Arrowood, Sherri Hale...> ;Investigational New Drugs. 2014 Apr 1
• 34 citations
  Phase I study of bevacizumab, everolimus, and panobinostat (LBH-589) in advanced solid tumors.
  John H. Strickler, Alexander Starodub, Jingquan Jia, Kellen L. Meadows, Andrew B. Nixon, Andrew Dellinger, Michael A. Morse, Hope E. Uronis, P. Kelly Marcom, S. Yousuf...> ;Cancer Chemotherapy and Pharmacology. 2012 Jun 29
• 31 citations
  A phase I study of bevacizumab, everolimus and panitumumab in advanced solid tumors
  Gordana Vlahovic, Kellen L. Meadows, Hope E. Uronis, Michael A. Morse, Gerard C. Blobe, Richard F. Riedel, S. Yousuf Zafar, A. Alvarez-Secord, Jon P. Gockerman, Alexan...> ;Cancer Chemotherapy and Pharmacology. 2012 May 26
• 10 citations
  Current Immunotherapeutic Strategies in Colon Cancer
  Michael A. Morse, Lee Langer, Alexander Starodub, Amy Hobeika, Timothy M. Clay, H. Kim Lyerly> ;Surgical Oncology Clinics of North America. 2007 Oct 1
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