AlexandraMaritzaOrtizMD

Obstetrics & Gynecology • Ponce, PR

Physician

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Office
Torre Medica San Lucas Ave. Tito Castro 909
Suite #704
Ponce, PR 00716
Phone+1 787-812-7527

Fax+1 787-290-1133
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Summary

Dr. Alexandra Ortiz, MD is an obstetrician/gynecologist in Ponce, Puerto Rico. She is currently licensed to practice medicine in Puerto Rico. She is affiliated with Hospital De Damas and St. Luke's Episcopal Hospital.

Education & Training

Hospital Episcopal San Lucas/Ponce School of MedicineResidency, Obstetrics and Gynecology, 1997 - 2001
Ponce Health Sciences University School of MedicineClass of 1997

Certifications & Licensure

PR State Medical License 2000 - 2025
American Board of Obstetrics and Gynecology Obstetrics & Gynecology

Awards, Honors, & Recognition

Fellow (FACOG) American Congress of Obstetricians and Gynecologists

Publications & Presentations

PubMed

3 citations
Simian Immunodeficiency Virus Infects Functionally Polarized Memory CD4 T Cells Equivalently In Vivo.
Stephen H. Lai, Carly E. Starke, Jacob K. Flynn, Carol L. Vinton, Alexandra M. Ortiz, Joseph C. Mudd, Jason M. Brenchley> ;Journal of Virology. 2019 Apr 17
30 citations
Experimental microbial dysbiosis does not promote disease progression in SIV-infected macaques
Alexandra M. Ortiz, Jacob K. Flynn, Sarah R. DiNapoli, Ivan Vujkovic-Cvijin, Carly E. Starke, Stephen H. Lai, MacKenzie K.E. Long, Ornella Sortino, Carol L. Vinton, Jo...> ;Nature Medicine. 2018 Jul 30
12 citations
Microbial translocation: translating simian immunodeficiency virus to HIV.
Alexandra M. Ortiz, Jason M. Brenchley> ;Current Opinion in HIV and AIDS. 2018 Jan 1
2 citations
Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in Chronically SIV-Infected Sooty Mangabeys
Alexandra M. Ortiz, Diane G. Carnathan, Joana Yu, Katherine M. Sheehan, Peter S. Kim, Arnold Reynaldi, Thomas H. Vanderford, Nichole R. Klatt, Jason M. Brenchley, Mile...> ;Plos One. 2016 May 26
65 citations
IL-21 and Probiotic Therapy Improve TH17 Frequencies, Microbial Translocation, and Microbiome in ARV-Treated, SIV-Infected Macaques
Alexandra M. Ortiz, Zachary Klase, Sarah R. DiNapoli, Ivan Vujkovic-Cvijin, Kirby Carmack, Molly R. Perkins, Nina Calantone, Carol L. Vinton, Nadeene E. Riddick, John ...> ;Mucosal Immunology. 2016 Mar 1
68 citations
Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques
Ivan Vujkovic-Cvijin, Louise A. Swainson, Simon Chu, Alexandra M. Ortiz, Clark A. Santee, Annalise Petriello, Richard M. Dunham, Douglas Fadrosh, Din L. Lin, Ali A. Fa...> ;Cell Reports. 2015 Nov 24
19 citations
Macrophages Are Phenotypically and Functionally Diverse across Tissues in Simian Immunodeficiency Virus-Infected and Uninfected Asian Macaques
Alexandra M. Ortiz, Sarah R. DiNapoli, Jason M. Brenchley> ;Journal of Virology. 2015 Jun 1
100 citations
Dysbiotic Bacteria Translocate in Progressive SIV Infection
Zachary Klase, Alexandra M. Ortiz, Claire Deleage, Joseph C. Mudd, Mariam Quinones, Elias Schwartzman, Nichole R. Klatt, Lauren A. Canary, Jacob D. Estes, Jason M. Bre...> ;Mucosal Immunology. 2015 Sep 19
95 citations
CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells.
Luca Micci, Xavier Alvarez, Robin I. Iriele, Alexandra M. Ortiz, Emily S. Ryan, Colleen S. McGary, Claire Deleage, Brigitte B. McAtee, Tianyu He, Cristian Apetrei, Kir...> ;Plos Pathogens. 2014 Oct 30
90 citations
Tissue Myeloid Cells in SIV-Infected Primates Acquire Viral DNA through Phagocytosis of Infected T Cells
Nina Calantone, Fan Wu, Zachary Klase, Claire Deleage, Molly R. Perkins, Kenta Matsuda, Elizabeth A. Thompson, Alexandra M. Ortiz, Carol L. Vinton, Ilnour Ourmanov, Ka...> ;Immunity. 2014 Sep 18
6 citations
Homeostatic Cytokines Induce CD4 Downregulation in African Green Monkeys Independently of Antigen Exposure To Generate Simian Immunodeficiency Virus-Resistant CD8αα T ...
Molly R. Perkins, Judith A. Briant, Nina Calantone, Sonya Whitted, Carol L. Vinton, Nichole R. Klatt, Ilnour Ourmanov, Alexandra M. Ortiz, Vanessa M. Hirsch, Jason M. ...> ;Journal of Virology. 2014 Sep 15
10 citations
Decreased plasticity of coreceptor use by CD4-independent SIV Envs that emerge in vivo
Nicholas Francella, Sarah T. C. Elliott, Yanjie Yi, Sarah E. Gwyn, Alexandra M. Ortiz, Bing Li, Guido Silvestri, Mirko Paiardini, Cynthia A. Derdeyn, Ronald G. Collman> ;Retrovirology. 2013 Nov 12
11 citations
CD4+ T Cells Support Production of Simian Immunodeficiency Virus Env Antibodies That Enforce CD4-Dependent Entry and Shape Tropism In Vivo
Nicholas Francella, Sarah E. Gwyn, Yanjie Yi, Bing Li, Peng Xiao, Sarah T. C. Elliott, Alexandra M. Ortiz, James A. Hoxie, Mirko Paiardini, Guido Silvestri, Cynthia A....> ;Journal of Virology. 2013 Sep 1
24 citations
Multifunctional Double-negative T Cells in Sooty Mangabeys Mediate T-helper Functions Irrespective of SIV Infection
Vasudha Sundaravaradan, Ramsey A. Saleem, Luca Micci, Melanie A. Gasper, Alexandra M. Ortiz, James G. Else, Guido Silvestri, Mirko Paiardini, John D. Aitchison, Donald...> ;Plos Pathogens. 2013 Jun 27
Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection.
Klatt NR, Estes JD, Sun X, Ortiz AM, Barber JS, Harris LD, Cervasi B, Yokomizo LK, Pan L, Vinton CL, Tabb B, Canary LA, Dang Q, Hirsch VM, Alter G, Belkaid Y, Lifson J...> ;Mucosal Immunol. 2012-11-01
96 citations
Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques.
Alexandra M. Ortiz, Nichole R. Klatt, Bing Li, Yanjie Yi, Brian Tabb, Xing Pei Hao, Lawrence R. Sternberg, Benton Lawson, Paul M. Carnathan, Elizabeth M. Cramer, Jessi...> ;The Journal of Clinical Investigation. 2011 Nov 1
150 citations
Low levels of SIV infection in sooty mangabey central memory CD4 + T cells are associated with limited CCR5 expression
Mirko Paiardini, Barbara Cervasi, Elane Reyes-Aviles, Luca Micci, Alexandra M. Ortiz, Ann Chahroudi, Carol L. Vinton, Shari N. Gordon, Steven E. Bosinger, Nicholas Fra...> ;Nature Medicine. 2011 Jun 26
12 citations
Limited CD4+ T cell proliferation leads to preservation of CD4+ T cell counts in SIV-infected sooty mangabeys.
Ming Liang Chan, Janka Petravic, Alexandra M. Ortiz, Jessica C. Engram, Mirko Paiardini, Deborah Cromer, Guido Silvestri, Miles P. Davenport> ;Proceedings. Biological Sciences. 2010 Dec 22
8 citations
Immunopathogenesis of AIDS
Alexandra M. Ortiz, Guido Silvestri> ;Current Infectious Disease Reports. 2009 Apr 18
27 citations
T-cell phenotypic and functional changes associated with social subordination and gene polymorphisms in the serotonin reuptake transporter in female rhesus monkeys.
Mirko Paiardini, Jackie B. Hoffman, Barbara Cervasi, Alexandra M. Ortiz, Fawn C Stroud, Guido Silvestri, Mark E. Wilson> ;Brain, Behavior, and Immunity. 2009 Feb 1
Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels.
Gribkoff VK, Starrett JE, Dworetzky SI, Hewawasam P, Boissard CG, Cook DA, Frantz SW, Heman K, Hibbard JR, Huston K, Johnson G, Krishnan BS, Kinney GG, Lombardo LA, Me...> ;Nat. Med.. 2001-04-01
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Professional Memberships

American College of Obstetricians and Gynecologists
Fellow

Hospital Affiliations

St. Luke's Episcopal HospitalPonce, Puerto Rico
Hospital De DamasPonce, Puerto Rico