AliJavaheriMDPhD

Cardiology • Saint Louis, MO

Heart Failure & Transplantation

Physician

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Office
Washington University School of Medicine
4940 Parkview
Saint Louis, MO 63110
Phone+1 314-362-1984
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Education & Training

University of Pennsylvania Health SystemFellowship, Cardiovascular Disease, 2010 - 2013
University of Chicago Division of the Biological Sciences The Pritzker School of MedicineClass of 2008

Certifications & Licensure

MO State Medical License 2016 - 2025
PA State Medical License 2010 - 2016

Awards, Honors, & Recognition

David L Williams Award Kern Lipid Conference, 2022

Clinical Trials

Novel Experimental COVID-19 Therapies Affecting Host Response Start of enrollment: 2021 Jul 15
Completed
Phase 2, Phase 3
Roles: Contact

Publications & Presentations

PubMed

Risks and benefits of intermittent fasting for the aging cardiovascular system.
Mualla Ozcan, Mahmoud Abdellatif, Ali Javaheri, Simon Sedej> ;The Canadian Journal of Cardiology. 2024 Feb 12
1 citations
Cardiac radiation improves ventricular function in mice and humans with cardiomyopathy.
Lauren N Pedersen, Carla Valenzuela Ripoll, Mualla Ozcan, Zhen Guo, Aynaz Lotfinaghsh, Shiyang Zhang, Sherwin Ng, Carla Weinheimer, Jessica Nigro, Attila Kovacs, Ahmed...> ;Med. 2023 Dec 8
12 citations
Sustained alternate-day fasting potentiates doxorubicin cardiotoxicity.
Mualla Ozcan, Zhen Guo, Carla Valenzuela Ripoll, Ahmed Diab, Antonino Picataggi, David Rawnsley, Aynaz Lotfinaghsh, Carmen Bergom, Jeff Szymanski, Daniel Hwang, Aarti ...> ;Cell Metabolism. 2023 Jun 6
Troponin elevation in the community: can you sleep on it?
Ali Javaheri, Julio A Chirinos> ;Sleep. 2023 Apr 12
18 citations
Proteasomal Degradation of TRAF2 Mediates Mitochondrial Dysfunction in Doxorubicin-Cardiomyopathy.
Rimpy Dhingra, Inna Rabinovich-Nikitin, Sonny Rothman, Matthew Guberman, Hongying Gang, Victoria Margulets, Davinder S Jassal, Keshav Narayan Alagarsamy, Sanjiv Dhingr...> ;Circulation. 2022 Sep 20
5 citations
Proteomic Analysis of Effects of Spironolactone in Heart Failure With Preserved Ejection Fraction.
Ali Javaheri, Ahmed Diab, Lei Zhao, Chenao Qian, Jordana B Cohen, Payman Zamani, Anupam Kumar, Zhaoqing Wang, Christina Ebert, Joseph Maranville, Erika Kvikstad, Micha...> ;Circulation. Heart Failure. 2022 Sep 1
29 citations
Metabolomic Profiling of the Effects of Dapagliflozin in Heart Failure With Reduced Ejection Fraction: DEFINE-HF.
Senthil Selvaraj, Zhuxuan Fu, Philip Jones, Lydia C Kwee, Sheryl L Windsor, Olga Ilkayeva, Christopher B Newgard, Kenneth B Margulies, Mansoor Husain, Silvio E Inzucch...> ;Circulation. 2022 Sep 13
8 citations
Dapagliflozin and Kidney Outcomes in Hospitalized Patients with COVID-19 Infection: An Analysis of the DARE-19 Randomized Controlled Trial.
Hiddo J L Heerspink, Remo H M Furtado, Otavio Berwanger, Gary G Koch, Felipe Martinez, Omar Mukhtar, Subodh Verma, Samvel B Gasparyan, Fengming Tang, Sheryl L Windsor,...> ;Clinical Journal of the American Society of Nephrology. 2022 May 1
5 citations
SARS-CoV-2-Associated Myocarditis: A Case of Direct Myocardial Injury.
Amanda K Verma, Olakanmi Olagoke, Jonathan D Moreno, Pan Ma, Jing Liu, Ali Javaheri, Kory Lavine, Muhammad F Masood, Chieh-Yu Lin, Rezaee, N.> ;Circulation. Heart Failure. 2022 Mar 1
12 citations
TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis.
Xiucui Ma, David R Rawnsley, Attila Kovacs, Moydul Islam, John T Murphy, Chen Zhao, Minu Kumari, Layla Foroughi, Haiyan Liu, Kevin Qi, Aaradhya Diwan, Krzysztof Hyrc, ...> ;JACC. Basic to Translational Science. 2022 Mar 1
7 citations
HDL Composition, Heart Failure, and Its Comorbidities.
Ahmed Diab, Carla Valenzuela Ripoll, Zhen Guo, Ali Javaheri> ;Frontiers in Cardiovascular Medicine. 2022 Jan 1
106 citations
Dapagliflozin in patients with cardiometabolic risk factors hospitalised with COVID-19 (DARE-19): a randomised, double-blind, placebo-controlled, phase 3 trial.
Mikhail Kosiborod, Russell Esterline, Remo H.M. Furtado, Jan Oscarsson, Samvel B. Gasparyan, Gary G. Koch, Felipe Martinez, Omar Mukhtar, Subodh Verma, Vijay K. Chopra...> ;The Lancet. Diabetes & Endocrinology. 2021 Sep 1
1 citations
A Survey of Aspirin Knowledge Among the General Public.
Joshua Owen, J. Logan Rush, Eric S. Armbrecht, Ali Javaheri, Ramona Behshad> ;Journal of General Internal Medicine. 2021 Jul 8
12 citations
Quantitative Proteomic Analysis of Diabetes Mellitus in Heart Failure With Preserved Ejection Fraction
Thomas C. Hanff, Jordana B. Cohen, Lei Zhao, Ali Javaheri, Payman Zamani, Stuart B. Prenner, Ernst Rietzschel, Yi Jia, Alice M. Walsh, Joseph Maranville, Zhaoqing Wang...> ;JACC. Basic to Translational Science. 2021 Feb 1
29 citations
Effects of dapagliflozin on prevention of major clinical events and recovery in patients with respiratory failure because of COVID-19: Design and rationale for the DAR...
Mikhail Kosiborod, Otavio Berwanger, Gary G. Koch, Felipe Martinez, Omar Mukhtar, Subodh Verma, Vijay K. Chopra, Ali Javaheri, Philip Ambery, Samvel B. Gasparyan, Joan...> ;Diabetes, Obesity & Metabolism. 2021 Apr 1
55 citations
Proteomic Signatures of Heart Failure in Relation to Left Ventricular Ejection Fraction.
Luigi Adamo, Jinsheng Yu, Cibele Rocha-Resende, Ali Javaheri, Richard D. Head, Douglas L. Mann> ;Journal of the American College of Cardiology. 2020 Oct 27
16 citations
Circulating Ceramide 16:0 in Heart Failure With Preserved Ejection Fraction
Ali Javaheri, Jeremy C. Allegood, L. Ashley Cowart, Julio A. Chirinos> ;Journal of the American College of Cardiology. 2020 May 5
32 citations
Reduced Apolipoprotein M and Adverse Outcomes Across the Spectrum of Human Heart Failure.
Julio A. Chirinos, Lei Zhao, Yi Jia, Cecilia Frej, Luigi Adamo, Douglas L. Mann, Swapnil V. Shewale, John S. Millar, Daniel J. Rader, Benjamin French, Jeff Brandimarto...> ;Circulation. 2020 May 5
32 citations
TFEB activation in macrophages attenuates postmyocardial infarction ventricular dysfunction independently of ATG5-mediated autophagy
Ali Javaheri, Geetika Bajpai, Antonino Picataggi, Smrithi Mani, Layla Foroughi, Hosannah Evie, Attila Kovacs, Carla J. Weinheimer, Krzystztof Hyrc, Qingli Xiao, Andrea...> ;JCI Insight. 2019 Nov 1
11 citations
Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival.
John T. Murphy, Haiyan Liu, Xiucui Ma, Alex Shaver, Brian M. Egan, Clara Oh, Alexander Boyko, Travis C Mazer, Samuel Ang, Rohan Khopkar, Ali Javaheri, Sandeep Kumar, X...> ;Plos Biology. 2019 May 14
37 citations
Transcription Factor EB Activation Rescues Advanced αB-Crystallin Mutation-Induced Cardiomyopathy by Normalizing Desmin Localization.
Xiucui Ma, Kartik Mani, Haiyan Liu, Attila Kovacs, John T. Murphy, Layla Foroughi, Brent A. French, Carla J. Weinheimer, Aldi T. Kraja, Ivor J. Benjamin, Joseph A. Hil...> ;Journal of the American Heart Association. 2019 Feb 19
1 citations
NO to Lysosomes: A Signal for Insulin Resistance in Obesity
Ali Javaheri, Abhinav Diwan> ;Cellular and Molecular Gastroenterology and Hepatology. 2019 Jan 1
13 citations
Lysosomes Mediate Benefits of Intermittent Fasting in Cardiometabolic Disease: The Janitor Is the Undercover Boss.
Kartik Mani, Ali Javaheri, Abhinav Diwan> ;Comprehensive Physiology. 2018 Sep 14
3 citations
Cholesterol efflux in the transplant patient.
Ali Javaheri, Sangita Sudharshan> ;Current Opinion in Endocrinology, Diabetes, and Obesity. 2018 Apr 1
110 citations
Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway
Haiyan Liu, Ali Javaheri, Rebecca J. Godar, John T. Murphy, Xiucui Ma, Jana Mahadevan, Krzysztof L. Hyrc, Paul Saftig, Connie A. Marshall, Michael L. McDaniel, Maria S...> ;Autophagy. 2017 Nov 25
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Press Mentions

New Clues Found to Help Protect Heart from Damage After Heart AttackNovember 2nd, 2019
Study: Radiation Therapy Shows Promise in Treating Heart FailureDecember 1st, 2023
Radiation Therapy in Mice and Men Helps Treat Heart Failure, Researchers FindDecember 7th, 2023
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