AliKeshavarzianMD

Gastroenterology • Chicago, IL

Inflammatory Bowel Disease

Professor of Medicine, Rush Medical College

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Office
1725 W Harrison St
Suite 207
Chicago, IL 60612
Phone+1 312-942-5861
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Education & Training

University of MarylandFellowship, Gastroenterology, 1984 - 1986
Tehran University of Medical Sciences School of MedicineClass of 1976

Certifications & Licensure

IL State Medical License 1986 - 2026
MD State Medical License 1985 - 1986
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Gastroenterology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
Fellow (AGAF) American Gastroenterological Association, 2006
Super Doctor SuperDoctors.com
Fellow (FACG) American College of Gastroenterology
Top MD Consumers Checkbook
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Clinical Trials

Dietary Treatment of Crohn's Disease Start of enrollment: 2006 Sep 01
Completed
Phase 1, Phase 2
Mind/Body Medicine and IBD Flare-Up Start of enrollment: 2007 Nov 01
Completed
Phase 1
Mind-Body Medicine and Ulcerative Colitis Start of enrollment: 2011 Aug 01
Completed
Not Applicable
Targeting Diet-Microbiome Interactions in the Pathogenesis of Parkinson's Disease Start of enrollment: 2018 May 05
Completed
Fecal Microbiota Transplantation (FMT) in Multiple Sclerosis Start of enrollment: 2018 Sep 25
Completed
Data-driven Identification for Substance Misuse Start of enrollment: 2023 Feb 01
Recruiting
Not Applicable
Roles: Contact
Chronotherapy of 5-Aminosalicylic Acid in Ulcerative Colitis Start of enrollment: 2021 Jul 09
Recruiting
Not Applicable
Roles: Contact, Principal Investigator
Gut Microbiota-Mediated Inflammatory Interactions Between AUD and HIV Infection Start of enrollment: 2024 Mar 06
Recruiting
Not Applicable
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

Brain derived neurotrophic factor and treatment outcomes among veterans attending an intensive treatment program for posttraumatic stress disorder.
Alyson K Zalta, Robin M Voigt, Sarah K Stevens, Philip Held, Shohreh Raeisi, Randy A Boley, Ali Keshavarzian, Mark H Pollack> ;Journal of Psychiatric Research. 2024 May 1
Distinct intestinal microbial signatures linked to accelerated systemic and intestinal biological aging.
Shalini Singh, Leila B Giron, Maliha W Shaikh, Shivanjali Shankaran, Phillip A Engen, Zlata R Bogin, Simona A Bambi, Aaron R Goldman, Joao L L C Azevedo, Lorena Orgaz,...> ;Microbiome. 2024 Feb 22
Outdoor Nighttime Light Exposure (Light Pollution) is Associated with Alzheimer's Disease.
Voigt, R., Ouyang, B., Keshavarzian, A.> ;Medrxiv. 2024 Feb 15
Increased Intestinal Permeability and Decreased Resiliency of the Intestinal Barrier in Alcoholic Liver Disease.
Swanson, G., Garg, K., Shaikh, M., Keshavarzian, A.> ;Clinical and Translational Gastroenterology. 2024 Feb 9
Evidence that the loss of colonic anti-microbial peptides may promote dysbiotic Gram-negative inflammaging-associated bacteria in aging mice.
Christopher B Forsyth, Phillip A Engen, Fabian Preuss, Ankur Naqib, Breanna A Palmen, Stefan J Green, Lijuan Zhang, Zlata R Bogin, Kristi Lawrence, Deepak Sharma, Gart...> ;Frontiers in Aging. 2024 Jan 1
Distinct Intestinal Microbial Signatures Linked to Accelerated Biological Aging in People with HIV.
Shalini Singh, Leila B Giron, Maliha W Shaikh, Shivanjali Shankaran, Phillip A Engen, Zlata R Bogin, Simona A Bambi, Aaron R Goldman, Joao L L C Azevedo, Lorena Orgaz,...> ;Research Square. 2023 Oct 30
43 citations
Serotonin reduction in post-acute sequelae of viral infection.
Andrea C Wong, Ashwarya S Devason, Iboro C Umana, Timothy O Cox, Lenka Dohnalová, Lev Litichevskiy, Jonathan Perla, Patrick Lundgren, Zienab Etwebi, Luke T Izzo, Jihee...> ;Cell. 2023 Oct 26
1 citations
Overview of the Gut-Brain Axis: From Gut to Brain and Back Again.
Zoë Post, Richard A Manfready, Ali Keshavarzian> ;Seminars in Neurology. 2023 Aug 1
Multi-omics approach to socioeconomic disparity in metabolic syndrome reveals roles of diet and microbiome.
Faraz Bishehsari, Michael Drees, Darbaz Adnan, Deepak Sharma, Stefan Green, Jane Koshy, Leila B Giron, Aaron Goldman, Mohamed Abdel-Mohsen, Heather E Rasmussen, Gregor...> ;Proteomics. 2023 Oct 1
1 citations
Curated and harmonized gut microbiome 16S rRNA amplicon data from dietary fiber intervention studies in humans.
Cynthia I Rodriguez, Ali Keshavarzian, Bruce R Hamaker, Feitong Liu, Genelle R Lunken, Heather Rasmussen, Hongwei Zhou, Julien Tap, Kelly S Swanson, Maria Ukhanova, Ma...> ;Scientific Data. 2023 Jun 2
Binge drinking alcohol and circadian misalignment in night shift nurses is associated with decreased resiliency to COVID-19 infection.
Garth R Swanson, Benjamin A Schwartz, Cara Joyce, Ali Keshavarzian> ;Alcohol, Clinical & Experimental Research. 2023 May 1
11 citations
An open label, non-randomized study assessing a prebiotic fiber intervention in a small cohort of Parkinson's disease participants.
Deborah A Hall, Robin M Voigt, Thaisa M Cantu-Jungles, Bruce Hamaker, Phillip A Engen, Maliha Shaikh, Shohreh Raeisi, Stefan J Green, Ankur Naqib, Christopher B Forsyt...> ;Nature Communications. 2023 Feb 18
4 citations
Siglec-9 Restrains Antibody-Dependent Natural Killer Cell Cytotoxicity against SARS-CoV-2.
Pratima Saini, Opeyemi S Adeniji, Devivasha Bordoloi, Jennifer Kinslow, Jeff Martinson, Danielle M Parent, Kai Ying Hong, Jane Koshy, Abhijeet J Kulkarni, Netanel F Zi...> ;Mbio. 2023 Feb 28
3 citations
Integrated Multi-Cohort Analysis of the Parkinson's Disease Gut Metagenome.
Joseph C Boktor, Gil Sharon, Leo A Verhagen Metman, Deborah A Hall, Phillip A Engen, Zoe Zreloff, Daniel J Hakim, John W Bostick, James Ousey, Danielle Lange, Gregory ...> ;Movement Disorders. 2023 Mar 1
8 citations
Gut microbiota dysbiosis in Parkinson disease: A systematic review and pooled analysis.
Sven Kleine Bardenhorst, Emanuele Cereda, Marco Severgnini, Michela Barichella, Gianni Pezzoli, Ali Keshavarzian, Alessandro Desideri, Daniele Pietrucci, Velma T E Aho...> ;European Journal of Neurology. 2023 Nov 1
2 citations
The Versatility and Diagnostic Potential of VOC Profiling for Noninfectious Diseases.
Micah Oxner, Allyson Trang, Jhalak Mehta, Christopher Forsyth, Barbara Swanson, Ali Keshavarzian, Abhinav Bhushan> ;BME Frontiers. 2023 Jan 1
Colon epithelial cell-specific Bmal1 deletion impairs bone formation in mice.
Frank C Ko, Sarah B Jochum, Brittany M Wilson, Amal Adra, Nikhil Patel, Hoomin Lee, Sherry Wilber, Maliha Shaikh, Christopher Forsyth, Ali Keshavarzian, Garth R Swanso...> ;Bone. 2023 Mar 1
3 citations
Impact of Chronotherapy on 6-Mercaptopurine Metabolites in Inflammatory Bowel Disease: A Pilot Crossover Trial.
Garth R Swanson, Mary Biglin, Vijit Chouhan, Sarah Jochum, Maliha Shaikh, Lauren Francey, Faraz Bishehsari, John Hogenesch, Ali Keshavarzian, Hannah Raff> ;Clinical and Translational Gastroenterology. 2023 Feb 1
3 citations
Alcohol use disorder as a potential risk factor for COVID-19 severity: A narrative review.
Christopher B Forsyth, Robin M Voigt, Garth R Swanson, Faraz Bishehsari, Maliha Shaikh, Lijuan Zhang, Phillip Engen, Ali Keshavarzian> ;Alcoholism, Clinical and Experimental Research. 2022 Nov 1
13 citations
A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice.
Reem Abdel-Haq, Johannes C M Schlachetzki, Joseph C Boktor, Thaisa M Cantu-Jungles, Taren Thron, Mengying Zhang, John W Bostick, Tahmineh Khazaei, Sujatha Chilakala, L...> ;Elife. 2022 Nov 8
5 citations
Direct Action of Non-Digestible Oligosaccharides against a Leaky Gut.
Maria Eleni Mavrogeni, Mostafa Asadpoor, Paul A J Henricks, Ali Keshavarzian, Gert Folkerts, Saskia Braber> ;Nutrients. 2022 Nov 7
2 citations
Colonic Epithelial Circadian Disruption Worsens Dextran Sulfate Sodium-Induced Colitis.
Sarah B Jochum, Phillip A Engen, Maliha Shaikh, Ankur Naqib, Sherry Wilber, Shohreh Raeisi, Lijuan Zhang, Shiwen Song, Gabriella Sanzo, Vijit Chouhan, Frank Ko, Zoe Po...> ;Inflammatory Bowel Diseases. 2023 Mar 1
8 citations
The SARS-CoV-2 S1 Spike Protein Promotes MAPK and NF-kB Activation in Human Lung Cells and Inflammatory Cytokine Production in Human Lung and Intestinal Epithelial Cells.
Christopher B Forsyth, Lijuan Zhang, Abhinav Bhushan, Barbara Swanson, Li Zhang, João I Mamede, Robin M Voigt, Maliha Shaikh, Phillip A Engen, Ali Keshavarzian> ;Microorganisms. 2022 Oct 10
7 citations
Changes in intestinal homeostasis and immunity in a cigarette smoke- and LPS-induced murine model for COPD: the lung-gut axis.
Lei Wang, Charlotte E Pelgrim, Lucía N Peralta Marzal, Stephanie Korver, Ingrid van Ark, Thea Leusink-Muis, Ardy van Helvoort, Ali Keshavarzian, Aletta D Kraneveld, Jo...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2022 Sep 1
23 citations
Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling.
Leila B Giron, Michael J Peluso, Jianyi Ding, Grace Kenny, Netanel F Zilberstein, Jane Koshy, Kai Ying Hong, Heather Rasmussen, Gregory E Miller, Faraz Bishehsari, Rob...> ;JCI Insight. 2022 Aug 8
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Press Mentions

Exploring Link Between Gut and Brain HealthOctober 17th, 2021
Following a Circadian Diet Could Help Keep Foodborne Illnesses at BayJuly 28th, 2021
7 Clear Signs You Might Have an Unhealthy GutNovember 21st, 2019
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