AlirezaFaridarMD

Neurology • Houston, TX

Assistant Professor of Neurology, Houston Methodist Hospital

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Office
6560 Fannin Street
Suite 750
Houston, TX 77030
Phone+1 713-441-1150

Fax+1 713-791-5125
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Education & Training

Methodist Hospital (Houston)Fellowship, Dementia Translational Fellowship, 2017 - 2018
Methodist Hospital (Houston)Residency, Neurology, 2013 - 2017
University of California San Francisco School of MedicinePost-Doctoral Fellowship, Neuroscience, 2011 - 2013
Tehran University of Medical Sciences School of MedicineClass of 2008

Certifications & Licensure

TX State Medical License 2017 - 2024
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

BrightFocus Alzheimer Disease Research Fellowship Award 2019
American Neurology Association (ANA) travel award 2013

Clinical Trials

Phase II Clinical Trial of Interleukin-2 in AD Start of enrollment: 2023 Mar 17
Recruiting
Phase 2
Roles: Contact, Principal Investigator
Systemic and Central Inflammation in AD Start of enrollment: 2023 Mar 17
Recruiting
Phase 2
Roles: Contact

Publications & Presentations

PubMed

A phase 1 open-label pilot study of low-dose interleukine-2 immunotherapy in patients with Alzheimer's disease.
Alireza Faridar, Abdulmunaim M Eid, Aaron D Thome, Weihua Zhao, David R Beers, Maria B Pascual, Mohammad O Nakawah, Gustavo C Roman, Charles S Davis, Michael Grundman,...> ;Translational Neurodegeneration. 2023 Nov 16
14 citations
Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimer's disease.
Alireza Faridar, Matthew Vasquez, Aaron D Thome, Zheng Yin, Hui Xuan, Shixiang Wen, Xuping Li, Jason R Thonhoff, Weihua Zhao, Hong Zhao, David R Beers, Stephen T C Won...> ;Acta Neuropathologica Communications. 2022 Sep 30
10 citations
Tregs Attenuate Peripheral Oxidative Stress and Acute Phase Proteins in ALS.
David R Beers, Jason R Thonhoff, Alireza Faridar, Aaron D Thome, Weihua Zhao, Shixiang Wen, Stanley H Appel> ;Annals of Neurology. 2022 Aug 1
11 citations
Extracellular Vesicles Derived FromExpanded Regulatory T Cells ModulateandInflammation.
Aaron D Thome, Jason R Thonhoff, Weihua Zhao, Alireza Faridar, Jinghong Wang, David R Beers, Stanley H Appel> ;Frontiers in Immunology. 2022 Jan 1
25 citations
Ex vivo expansion of dysfunctional regulatory T lymphocytes restores suppressive function in Parkinson's disease.
Aaron D. Thome, Farah Atassi, Jinghong Wang, Alireza Faridar, Weihua Zhao, Jason R. Thonhoff, David R. Beers, Eugene C. Lai, Stanley H. Appel> ;NPJ Parkinson's Disease. 2021 May 13
22 citations
Neuroinflammation is highest in areas of disease progression in semantic dementia
Belen Pascual, Quentin Funk, Paolo Zanotti-Fregonara, Matthew D. Cykowski, Mattia Veronese, Elijah Rockers, Kathleen Bradbury, Meixiang Yu, Mohammad Obadah Nakawah, Gu...> ;Brain. 2021 Jun 22
4 citations
Serum programmed cell death proteins in amyotrophic lateral sclerosis.
David R. Beers, Weihua Zhao, Jason R. Thonhoff, Alireza Faridar, Aaron D. Thome, Shixiang Wen, Jinghong Wang, Stanley H. Appel> ;Brain, Behavior, & Immunity - Health. 2021 Jan 26
Early detection of metabolic changes using microdialysis during and after experimental kidney transplantation in a porcine model.
Fonouni H, Esmaeilzadeh M, Jarahian P, Rad MT, Golriz M, Faridar A, Hafezi M, Jafarieh S, Kashfi A, Yazdi SH, Soleimani M, Longerich T, Shevchenko M, Sakowitz O, Schmi...> ;Surgical innovation.
Plasma homocysteine level in patients with Behcet's disease with or without thrombosis.
Shahram F, Faridar A, Hamedani MG, Nadji A, Naderi N, Mojarad Shafiee N, Rasker JJ, Davatchi F> ;Archives of Iranian medicine.
Validation of the International Criteria for Behçet's disease (ICBD) in Iran.
Davatchi F, Sadeghi Abdollahi B, Shahram F, Nadji A, Chams-Davatchi C, Shams H, Naderi N, Akhlaghi M, Faezi T, Faridar A> ;International journal of rheumatic diseases.
Generation of immunogenic and tolerogenic clinical-grade dendritic cells.
Kalantari T, Kamali-Sarvestani E, Ciric B, Karimi MH, Kalantari M, Faridar A, Xu H, Rostami A> ;Immunologic research.
8 citations
Long-Term Follow-Up of Kidney Transplant Recipients With Polycystic Kidney Disease.
Arianeb Mehrabi, Mohammad Golriz, Julia Maier, Hamidreza Fonouni, Camelia Garoussi, Mohammadreza Hafezi, Nassim Fard, Alireza Faridar, Nahid Rezaei, Manfred Wiesel, Ma...> ;Experimental and Clinical Transplantation. 2015 Oct 1
26 citations
Elevated acute phase proteins reflect peripheral inflammation and disease severity in patients with amyotrophic lateral sclerosis.
David R. Beers, Weihua Zhao, Daniel Neal, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Shixiang Wen, Jinghong Wang, Stanley H. Appel> ;Scientific Reports. 2020 Sep 17
39 citations
Restoring regulatory T-cell dysfunction in Alzheimer's disease through ex vivo expansion.
Alireza Faridar, Aaron D. Thome, Weihua Zhao, Jason R. Thonhoff, David R. Beers, Belen Pascual, Joseph C. Masdeu, Stanley H. Appel> ;Brain Communications. 2020 Jul 1
22 citations
Immunosuppressive Functions of M2 Macrophages Derived from iPSCs of Patients with ALS and Healthy Controls.
Weihua Zhao, David R. Beers, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Jinghong Wang, Shixiang Wen, Loren Ornelas, Dhruv Sareen, Helen S. Goodridge, Clive N....> ;Iscience. 2020 Jun 26
44 citations
Functional alterations of myeloid cells during the course of Alzheimer’s disease
Aaron D. Thome, Alireza Faridar, David R. Beers, Jason R. Thonhoff, Weihua Zhao, Shixiang Wen, Belen Pascual, Joseph C. Masdeu, Stanley H. Appel> ;Molecular Neurodegeneration. 2018 Nov 13
3 citations
Brain CT and MRI: differential diagnosis of imaging findings.
Joseph C. Masdeu, Rajan R Gadhia, Alireza Faridar> ;Handbook of Clinical Neurology. 2016 Jan 1
Is microdialysis useful for early detection of acute rejection after kidney transplantation?
Fonouni H, Golriz M, Majlesara A, Faridar A, Esmaeilzadeh M, Jarahian P, Rad MT, Hafezi M, Garoussi C, Macher-Goeppinger S, Longerich T, Orakcioglu B, Sakowitz OW, Meh...> ;International journal of surgery (London, England). 2015-04-09
18 citations
Comparison of serum vitamin D level in multiple sclerosis patients, their siblings, and healthy controls.
Ghazaleh Eskandari, Mahsa Ghajarzadeh, Mir Saeed Yekaninejad, Mohammad Ali Sahraian, Razieh Gorji, Faezeh Rajaei, Abbas Norouzi-Javidan, Alireza Faridar, Amirreza Azimi> ;Iranian Journal of Neurology. 2015 Apr 4
42 citations
Mapk/Erk activation in an animal model of social deficits shows a possible link to autism.
Alireza Faridar, Dorothy M. Jones-Davis, Eric Rider, Jiang Li, Ilan Gobius, Laura Morcom, Linda J. Richards, Saunak Sen, Elliott H. Sherr> ;Molecular Autism. 2014 Dec 22
Brain metastasis from gastrointestinal cancers: a systematic review.
Esmaeilzadeh M, Majlesara A, Faridar A, Hafezi M, Hong B, Esmaeilnia-Shirvani H, Neyazi B, Mehrabi A, Nakamura M> ;International journal of clinical practice. 2014-03-25
The relationship between plasma homocysteine level and HLA-B51 in patients with Behcet's disease: a case-control study.
Shadmanfar S, Shahram F, Nadji A, Akhlaghi M, Faezi ST, Sadeghi-Abdollahi B, Faridar A, Madanchi N, Davatchi F> ;International journal of rheumatic diseases. 2014-01-16
19 citations
Vitamin D and multiple sclerosis: a critical review and recommendations on treatment
Alireza Faridar, Ghazaleh Eskandari, Mohammad Ali Sahraian, Alireza Minagar, Amirreza Azimi> ;Acta Neurologica Belgica. 2012 Jul 6
45 citations
Therapeutic Hypothermia in Stroke and Traumatic Brain Injury
Alireza Faridar, Eric M. Bershad, Tenbit Emiru, Paul A. Iaizzo, Jose I. Suarez, Afshin A. Divani> ;Frontiers in Neurology. 2011 Dec 27
Intracranial aneurysms: review of current treatment options and outcomes.
Seibert B, Tummala RP, Chow R, Faridar A, Mousavi SA, Divani AA> ;Frontiers in neurology. 2011-07-08
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Press Mentions

Coya Therapeutics Reports Data from Alzheimer’s Disease Therapy TrialApril 3rd, 2023
Coya Therapeutics Presents Biomarker Data on Neuroinflammatory Pathways in Frontotemporal Dementia (FTD) at the AD/PD 2024 ConferenceMarch 7th, 2024
Coya Therapeutics to Present Data on Immune System and Regulatory T Cell (Treg) Contributions in Frontotemporal Dementia (FTD) Patients at AD/PD 2024 ConferenceMarch 1st, 2024
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