AlixAshareMD

PubMed

• 1 citations
  Comparative effects of CFTR modulators on phagocytic, metabolic and inflammatory profiles of CF and nonCF macrophages.
  Daniel S Aridgides, Diane L Mellinger, Lorraine L Gwilt, Thomas H Hampton, Dallas L Mould, Deborah A Hogan, Alix Ashare> ;Scientific Reports. 2023 Jul 25
• The Impact of Chronic Electronic Cigarette Use on Alveolar Macrophage Lipid Content: Case Report.
  Molly Ruttenberg, David Armstrong, Diane Mellinger, James Carroll, Alix Ashare> ;Archives of Clinical and Medical Case Reports. 2022 Jan 1
• 16 citations
  Model Systems to Study the Chronic, Polymicrobial Infections in Cystic Fibrosis: Current Approaches and Exploring Future Directions.
  George A. O'Toole, Aurélie Crabbé, Rolf Kümmerli, John J. LiPuma, Jennifer M. Bomberger, Jane C. Davies, Dominique H. Limoli, Vanessa V. Phelan, James B. Bliska, Willi...> ;Mbio. 2021 Sep 21
• Aspergillus fumigatus In-Host HOG Pathway Mutation for Cystic Fibrosis Lung Microenvironment Persistence.
  Brandon S. Ross, Lotus A. Lofgren, Alix Ashare, Jason E. Stajich, Robert A. Cramer> ;Mbio. 2021 Aug 31
• 15 citations
  Healthy versus inflamed lung environments differentially effect MSCs
  Sara Rolandsson Enes, Thomas H. Hampton, Jayita Barua, David H. McKenna, Claudia C. dos Santos, Eyal Amiel, Alix Ashare, Kathleen D. Liu, Anna Krasnodembskaya, Karen E...> ;The European Respiratory Journal. 2021 Apr 1
• 5 citations
  Balancing Positive and Negative Selection: In Vivo Evolution of Candida lusitaniae MRR1.
  Elora G. Demers, Jason E. Stajich, Alix Ashare, Patricia Occhipinti, Deborah A. Hogan> ;Mbio. 2021 Mar 30
• 3 citations
  Safety of research bronchoscopy with BAL in stable adult patients with cystic fibrosis.
  Daniel S. Aridgides, John A. Dessaint, Graham T. Atkins, James Carroll, Alix Ashare> ;Plos One. 2021 Jan 22
• 6 citations
  CF monocyte-derived macrophages have an attenuated response to extracellular vesicles secreted by airway epithelial cells.
  Katja Koeppen, Amanda B. Nymon, Roxanna Barnaby, Zhongyou Li, Thomas H. Hampton, Alix Ashare, Bruce A Stanton> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2021 Jan 20
• 7 citations
  Exposure to extracellular vesicles from Pseudomonas aeruginosa result in loss of DNA methylation at enhancer and DNase hypersensitive site regions in lung macrophages.
  Min Kyung Lee, David A. Armstrong, Haley F. Hazlett, John A. Dessaint, Diane L. Mellinger, Daniel S. Aridgides, Brock C. Christensen, Alix Ashare> ;Epigenetics. 2021 Nov 2
• 18 citations
  Differential effects of the cystic fibrosis lung inflammatory environment on mesenchymal stromal cells.
  Soraia C. Abreu, Thomas H. Hampton, Evan T Hoffman, Jacob Dearborn, Alix Ashare, Karatatiwant Singh Sidhu, Dwight E. Matthews, David H. McKenna, Eyal Amiel, Jayita Bar...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2020 Sep 9
• 34 citations
  SARS-CoV-2 (COVID-19) and cystic fibrosis.
  Bruce A Stanton, Thomas H. Hampton, Alix Ashare> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2020 Sep 1
• 18 citations
  Extracellular Vesicles from Pseudomonas aeruginosa Suppress MHC-Related Molecules in Human Lung Macrophages.
  David A. Armstrong, Min Kyung Lee, Haley F. Hazlett, John A. Dessaint, Diane L. Mellinger, Daniel S. Aridgides, Gregory M. Hendricks, Moemen Abdalla, Brock C. Christen...> ;Immunohorizons. 2020 Aug 1
• 20 citations
  Altered iron metabolism in cystic fibrosis macrophages: the impact of CFTR modulators and implications for Pseudomonas aeruginosa survival.
  Haley F. Hazlett, Thomas H. Hampton, Daniel S. Aridgides, David A. Armstrong, John A. Dessaint, Diane L. Mellinger, Amanda B. Nymon, Alix Ashare> ;Scientific Reports. 2020 Jul 2
• 113 citations
  Lung function and microbiota diversity in cystic fibrosis
  Leah Cuthbertson, Alan W. Walker, Anna Oliver, Geraint B. Rogers, Damian W. Rivett, Thomas H. Hampton, Alix Ashare, J. Stuart Elborn, Anthony De Soyza, Mary P. Carroll...> ;Microbiome. 2020 Apr 2
• 16 citations
  Dissociation of systemic and mucosal autoimmunity in cystic fibrosis
  Jomkuan Theprungsirikul, Sladjana Skopelja-Gardner, R.E. Meagher, John P. Clancy, Edith T. Zemanick, Alix Ashare, William F. C. Rigby> ;Journal of Cystic Fibrosis. 2020 Mar 1
• 12 citations
  DNA Methylation Changes in Regional Lung Macrophages Are Associated with Metabolic Differences.
  David A. Armstrong, Youdinghuan Chen, John A. Dessaint, Daniel S. Aridgides, Jacqueline Y. Channon, Diane L. Mellinger, Brock C. Christensen, Alix Ashare> ;Immunohorizons. 2019 Jul 1
• 29 citations
  Functional and metabolic impairment in cigarette smoke-exposed macrophages is tied to oxidative stress.
  Daniel S. Aridgides, Diane L. Mellinger, David A. Armstrong, Haley F. Hazlett, John A. Dessaint, Thomas H. Hampton, Graham T. Atkins, James Carroll, Alix Ashare> ;Scientific Reports. 2019 Jul 3
• 32 citations
  Identifying aerosolized cyanobacteria in the human respiratory tract: A proposed mechanism for cyanotoxin-associated diseases.
  Matthew W. Bough, Darius Seidler, James Carroll, Alix Ashare, Angeline S. Andrew, Gregory J. Tsongalis, Louis J. Vaickus, Patricia L. Henegan, Tanya Butt, Elijah W. St...> ;The Science of the Total Environment. 2018 Dec 15
• 20 citations
  Genome-wide DNA methylation profiling shows a distinct epigenetic signature associated with lung macrophages in cystic fibrosis
  Youdinghuan Chen, David A. Armstrong, Lucas A. Salas, Haley F. Hazlett, Amanda B. Nymon, John A. Dessaint, Daniel S. Aridgides, Diane L. Mellinger, Xiaoying Liu, Brock...> ;Clinical Epigenetics. 2018 Dec 10
• 37 citations
  Evolution of drug resistance in an antifungal-naive chronic Candida lusitaniae infection.
  Elora G. Demers, Amy R. Biermann, Sawyer Masonjones, Alex W. Crocker, Alix Ashare, Jason E. Stajich, Deborah A. Hogan> ;Proceedings of the National Academy of Sciences of the United States of America. 2018 Nov 20
• 16 citations
  Pre-Analytical Handling Conditions and Small RNA Recovery from Urine for miRNA Profiling.
  David A. Armstrong, John A. Dessaint, Carol S. Ringelberg, Haley F. Hazlett, Louisa Howard, Moemen Abdalla, Roxanna Barnaby, Bruce A. Stanton, Mark A. Cervinski, Alix ...> ;The Journal of Molecular Diagnostics. 2018 Sep 1
• 15 citations
  Profiling of Bacterial and Fungal Microbial Communities in Cystic Fibrosis Sputum Using RNA
  Nora Grahl, Emily L. Dolben, Laura M. Filkins, Alex W. Crocker, Sven D. Willger, Hilary G. Morrison, Mitchell L. Sogin, Alix Ashare, Alex H. Gifford, Nicholas J. Jacob...> ;Msphere. 2018 Aug 29
• 29 citations
  VISTA deficiency attenuates antibody-induced arthritis and alters macrophage gene expression in response to simulated immune complexes.
  Sabrina Ceeraz, Susan K. Eszterhas, Petra A. Sergent, David A. Armstrong, Alix Ashare, Thomas Broughton, Li Wang, Dov A. Pechenick, Christopher M. Burns, Randolph J. N...> ;Arthritis Research & Therapy. 2017 Dec 8
• 52 citations
  Lumacaftor (VX-809) restores the ability of CF macrophages to phagocytose and kill Pseudomonas aeruginosa
  Roxanna Barnaby, Katja Koeppen, Amanda B. Nymon, Thomas H. Hampton, Brent Berwin, Alix Ashare, Bruce A. Stanton> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2018 Mar 1
• 30 citations
  Pulmonary microRNA profiling: implications in upper lobe predominant lung disease.
  David A. Armstrong, Amanda B. Nymon, Carol S. Ringelberg, Corina Lesseur, Haley F. Hazlett, Louisa Howard, Carmen J. Marsit, Alix Ashare> ;Clinical Epigenetics. 2017 May 30
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Journal Articles

• Evolution of Drug Resistance in an Antifungal-Naive Chronic Candida Lusitaniae Infection  
  Alix Ashare, MD, Proceedings of the National Academy of Sciences