AllenMichaelSpiegelMD

PubMed

• 2 citations
  The stem cell wars: a dispatch from the front.
  Allen M. Spiegel> ;Transactions of the American Clinical and Climatological Association. 2013 Jan 1
• 11 citations
  ‘Personalized Medicine’ To Identify Genetic Risks For Type 2 Diabetes And Focus Prevention: Can It Fulfill Its Promise?
  Allen M. Spiegel, Meredith Hawkins> ;Health Affairs. 2012 Jan 1
• 2 citations
  Future diagnostic and therapeutic trends in endocrine cancers.
  Allen M. Spiegel, Steven K. Libutti> ;Seminars in Oncology. 2010 Dec 1
• 2 citations
  Commentary: new guidelines for NIH peer review: improving the system or undermining it?
  Allen M. Spiegel> ;Academic Medicine. 2010 May 1
• 17 citations
  Pathophysiology of primary hyperparathyroidism.
  Allen M. Spiegel> ;Journal of Bone and Mineral Research. 2009 Dec 3
• 56 citations
  Recapitulation of pancreatic neuroendocrine tumors in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of Men1.
  H.-C. Jennifer Shen, Mei He, Anathea C. Powell, Asha Adem, Dominique Lorang, Charles K. Heller, Amelia C. Grover, Kris Ylaya, Stephen M. Hewitt, Stephen J. Marx, Allen...> ;Cancer Research. 2009 Mar 1
• 63 citations
  The parathyroid/pituitary variant of multiple endocrine neoplasia type 1 usually has causes other than p27Kip1 mutations.
  Atsushi Ozawa, Sunita K. Agarwal, Carmen M. Mateo, A. Lee Burns, Terri S. Rice, Patricia A. Kennedy, Caitlin M. Quigley, William F. Simonds, Lee S. Weinstein, Settara ...> ;The Journal of Clinical Endocrinology and Metabolism. 2007 May 1
• 11 citations
  Functional Effects of Monoclonal Antibodies to the Purified Amino-Terminal Extracellular Domain of the Human Ca2+ Receptor
  Jianxin Hu, Guadalupe Reyes-Cruz, Paul K. Goldsmith, Nicole M. Gantt, Jeffery L. Miller, Allen M. Spiegel> ;Journal of Bone and Mineral Research. 2007 Apr 1
• 72 citations
  Parathyroid-Specific Double Knockout of Gq and G11 α-Subunits Leads to a Phenotype Resembling Germline Knockout of the Extracellular Ca2+-Sensing Receptor
  Nina Wettschureck, Eunah Lee, Steven K. Libutti, Stefan Offermanns, Pamela Gehron Robey, Allen M. Spiegel> ;Molecular Endocrinology. 2007 Jan 1
• 39 citations
  A missense mutation in the seven-transmembrane domain of the human Ca2+ receptor converts a negative allosteric modulator into a positive allosteric modulator.
  Jianxin Hu, Jian-kang Jiang, Stefano Costanzi, Craig J. Thomas, Wu Yang, Jean H.M. Feyen, Kenneth A. Jacobson, Allen M. Spiegel> ;The Journal of Biological Chemistry. 2006 Jul 28
• 8 citations
  NIH research on obesity and type 2 diabetes: providing the scientific evidence base for actions to improve health
  Allen M. Spiegel, Elizabeth G. Nabel> ;Nature Medicine. 2006 Jan 1
• 30 citations
  Executive summary of the Strategic Plan for National Institutes of Health Obesity Research
  Allen M. Spiegel, Barbara M. Alving> ;The American Journal of Clinical Nutrition. 2005 Jul 1
• 58 citations
  A Region in the Seven-transmembrane Domain of the Human Ca2+ Receptor Critical for Response to Ca2+
  Jianxin Hu, Stuart J. McLarnon, Stefano Mora, Jian-kang Jiang, Craig J. Thomas, Kenneth A. Jacobson, Allen M. Spiegel> ;The Journal of Biological Chemistry. 2005 Feb 11
• 164 citations
  Genome-Wide Analysis of Menin Binding Provides Insights into MEN1 Tumorigenesis
  Peter C. Scacheri, Sean Davis, Duncan T. Odom, Gregory E. Crawford, Stacie Perkins, Mohamad J. Halawi, Sunita K. Agarwal, Stephen J. Marx, Allen M. Spiegel, Paul S. Me...> ;Plos Genetics. 2005 Jan 1
• 45 citations
  Homozygous loss of menin is well tolerated in liver, a tissue not affected in MEN1
  Peter C. Scacheri, Judy S. Crabtree, Alyssa L. Kennedy, Gary P. Swain, Jerrold M. Ward, Stephen J. Marx, Allen M. Spiegel, Francis S. Collins> ;Mammalian Genome. 2004 Nov 1
• 22 citations
  Pancreatic insulinomas in multiple endocrine neoplasia, type I knockout mice can develop in the absence of chromosome instability or microsatellite instability.
  Peter C. Scacheri, Alyssa L. Kennedy, Koei Chin, Meghan T. Miller, J. Graeme Hodgson, Joe W. Gray, Stephen J. Marx, Allen M. Spiegel, Francis S. Collins> ;Cancer Research. 2004 Oct 1
• 5 citations
  Focus on hereditary endocrine neoplasia
  Allen M. Spiegel> ;Cancer Cell. 2004 Oct 1
• 20 citations
  Autosomal dominant hypocalcemia in monozygotic twins caused by a de novo germline mutation near the amino-terminus of the human calcium receptor
  Jianxin Hu, Stefano Mora, Giovanna Weber, I. Zamproni, Maria Carla Proverbio, Allen M. Spiegel> ;Journal of Bone and Mineral Research. 2004 Apr 1
• 104 citations
  Molecular Pathology of the MEN1 Gene
  Sunita K. Agarwal, A. Lee Burns, Karen E. Sukhodolets, Patricia A. Kennedy, Victor H. Obungu, Alison B. Hickman, Michael E. Mullendore, Ira Whitten, Monica C. Skarulis...> ;Annals of the New York Academy of Sciences. 2004 Apr 1
• 10 citations
  Gland size is associated with changes in gene expression profiles in sporadic parathyroid adenomas.
  Jennifer E. Rosen, Nick G. Costouros, Dominique Lorang, A. Lee Burns, H. Richard Alexander, Monica C. Skarulis, Craig Cochran, James F. Pingpank, Stephen J. Marx, Alle...> ;Annals of Surgical Oncology. 2004 Feb 1
• 161 citations
  Inherited diseases involving g proteins and g protein-coupled receptors.
  Allen M. Spiegel, Lee S. Weinstein> ;Annual Review of Medicine. 2004 Jan 27
• 79 citations
  Parathyroid gland-specific deletion of the mouse Men1 gene results in parathyroid neoplasia and hypercalcemic hyperparathyroidism.
  Steven K. Libutti, Judy S. Crabtree, Dominique Lorang, A. Lee Burns, C.M. Mazzanti, Stephen M. Hewitt, Sarah O'Connor, Jerrold M. Ward, Michael R. Emmert-Buck, Alan T....> ;Cancer Research. 2003 Nov 15
• 95 citations
  Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter.
  Sunita K. Agarwal, Elizabeth A. Novotny, Judy S. Crabtree, Jonathan B. Weitzman, Moshe Yaniv, A. Lee Burns, Settara C. Chandrasekharappa, Francis S. Collins, Allen M. ...> ;Proceedings of the National Academy of Sciences of the United States of America. 2003 Sep 16
• 185 citations
  Of Mice and MEN1: Insulinomas in a Conditional Mouse Knockout
  Judy S. Crabtree, Peter C. Scacheri, Jerrold M. Ward, Sara McNally, Gary P. Swain, Cristina Montagna, Jeffrey H. Hager, Douglas Hanahan, Helena Edlund, Mark A. Magnuso...> ;Molecular and Cellular Biology. 2003 Sep 1
• 75 citations
  Naturally occurring mutations of the extracellular Ca2+-sensing receptor: implications for its structure and function
  Jianxin Hu, Allen M. Spiegel> ;Trends in Endocrinology and Metabolism. 2003 Aug 1
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Lectures

• 5th Annual Personalized Medicine World Conference 
  American Medical Informatics Association (AMIA), Mountain View, California - 1/28/2013