AlpaMNickMDMS(She/Her)

Obstetrics & Gynecology • Katy, TX

General Gynecology, Gynecologic Oncology

Physician

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Office
Texas Oncology-Katy
1331 W. Grand Pkwy. N., Suite 340
Katy, TX 77493
Phone+1 281-392-2757

Fax+1 281-392-4794
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Summary

I am a board certified gynecologic oncologist dedicated to diagnosing, treating and preventing every type of gynecologic cancer. I offer the most advanced treatment options for gynecologic cancers including robotic and laparoscopic surgery, lymphatic mapping, novel chemotherapy treatment options, clinical research trials, genetic counseling and testing for women with a family history of gynecologic cancer, ovarian cancer screening for women at high risk, colposcopy evaluation of the cervix, vulva and vagina, and surgical management of complex gynecological disorders. Care for my patient's extends beyond active treatment. I help patients move on to the next phase of life by providing guideline-based care designed specifically for cancer survivors.

Types of cancers I specialize in treating:
Uterine (endometrial) cancer
Ovarian cancer
Fallopian tube cancer
Peritoneal cancer
Cervical cancer
Vaginal cancer
Vulvar cancer
Gynecologic sarcomas
Gestational trophoblastic disease
Pre-invasive diseases of the genital tract

Education & Training

University of Texas M D Anderson Cancer CenterFellowship, Gynecologic Oncology, 2007 - 2011
Vanderbilt University Medical CenterResidency, Obstetrics and Gynecology, 2003 - 2007
LSU School of Medicine in ShreveportClass of 2003

Certifications & Licensure

TX State Medical License 2009 - 2026
KY State Medical License 2016 - 2025
TN State Medical License 2016 - 2025
American Board of Obstetrics and Gynecology Obstetrics & Gynecology
American Board of Obstetrics and Gynecology Gynecologic Oncology

Awards, Honors, & Recognition

Fellow (FACOG) American College of Obstetricians and Gynecologists

Clinical Trials

Laparoscopic Approach to Cervical Cancer Start of enrollment: 2008 Jan 01
Completed
Not Applicable
Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer Start of enrollment: 2014 Feb 27
Active, not recruiting
Phase 2, Phase 3

Publications & Presentations

PubMed

1 citations
Immune environment and antigen specificity of the T cell receptor repertoire of malignant ascites in ovarian cancer.
Kyoko Yoshida-Court, Tatiana V Karpinets, Aparna Mitra, Travis N Solley, Stephanie Dorta-Estremera, Travis T Sims, Andrea Y Delgado Medrano, Molly B El Alam, Mustapha ...> ;Plos One. 2023 Jan 1
3 citations
Clinical analysis of pathologic complete responders in advanced-stage ovarian cancer.
Christopher J LaFargue, Katelyn F Handley, Nicole D Fleming, Alpa M Nick, Anca Chelariu-Raicu, Bryan Fellman, Tara Castellano, Aiko Ogasawara, Marianne Hom-Tedla, Erin...> ;Gynecologic Oncology. 2022 Apr 1
3 citations
Endothelial p130cas confers resistance to anti-angiogenesis therapy.
Yunfei Wen, Anca Chelariu-Raicu, Sujanitha Umamaheswaran, Alpa M Nick, Elaine Stur, Pahul Hanjra, Dahai Jiang, Nicholas B Jennings, Xiuhui Chen, Deanna Glassman, Gabri...> ;Cell Reports. 2022 Jan 25
Editor's Note: Functional Roles of Src and Fgr in Ovarian Carcinoma
Hye-Sun Kim, Hee Dong Han, Guillermo N. Armaiz-Pena, Rebecca L. Stone, Eun Ji Nam, Jeong-Won Lee, Mian M.K. Shahzad, Alpa M. Nick, Sun Joo Lee, Ju Won Roh, Masato Nish...> ;Clinical Cancer Research. 2021 Aug 1
Editor's Note: Therapeutic Targeting of ATP7B in Ovarian Carcinoma.
Lingegowda S. Mangala, Vesna Zuzel, Rosemarie Schmandt, Erik S. Leshane, Jyotsna B. Halder, Guillermo N. Armaiz-Pena, Whitney A. Spannuth, Takemi Tanaka, Mian M.K. Sha...> ;Clinical Cancer Research. 2021 Aug 1
Editor's Note: Targeted Gene Silencing Using RGD-Labeled Chitosan Nanoparticles.
Hee Dong Han, Lingegowda S. Mangala, Jeong-Won Lee, Mian M.K. Shahzad, Hye Sun Kim, Deyu Shen, Eun Ji Nam, Edna M. Mora, Rebecca L. Stone, Chunhua Lu, Sun Joo Lee, Ju ...> ;Clinical Cancer Research. 2021 Aug 1
18 citations
Extracellular vesicles derived from ascitic fluid enhance growth and migration of ovarian cancer cells.
Aparna Mitra, Kyoko Yoshida-Court, Travis Solley, Megan Mikkelson, Chi Lam Au Yeung, Alpa M. Nick, Karen H. Lu, Ann H. Klopp> ;Scientific Reports. 2021 Apr 28
5 citations
A multicenter open-label randomized phase II trial of paclitaxel plus EP-100, a novel LHRH receptor-targeted, membrane-disrupting peptide, versus paclitaxel alone for ...
Anca Chelariu-Raicu, Alpa Nick, Renata R. Urban, Mary E. Gordinier, Carola Leuschner, Linda M Bavisotto, Graziela Zibetti Dal Molin, John K. Whisnant, Robert L. Coleman> ;Gynecologic Oncology. 2021 Feb 1
Pathologic distribution at the time of interval tumor reductive surgery informs personalized surgery for high-grade ovarian cancer
Courtney D Bailey, Rebecca A. Previs, Bryan Fellman, Tarrik M. Zaid, Marilyn Huang, Alaina J. Brown, Ahmed Enbaya, Nyla Balakrishnan, Russell Broaddus, Diane C. Bodurk...> ;International Journal of Gynecological Cancer. 2021 Feb 1
42 citations
Prospective phase II trial of levonorgestrel intrauterine device: nonsurgical approach for complex atypical hyperplasia and early-stage endometrial cancer.
Shannon N. Westin, Bryan Fellman, Charlotte C. Sun, Russell Broaddus, Misty L. Woodall, Navdeep Pal, Diana L. Urbauer, Lois M. Ramondetta, Kathleen M. Schmeler, Pamela...> ;American Journal of Obstetrics and Gynecology. 2021 Feb 1
27 citations
The role of neoadjuvant chemotherapy in the management of low-grade serous carcinoma of the ovary and peritoneum: Further evidence of relative chemoresistance.
Lauren P. Cobb, Charlotte C. Sun, Revathy B. Iyer, Alpa M. Nick, Nicole D. Fleming, Shannon N. Westin, Anil K. Sood, Kwong Kwok Wong, Elvio G. Silva, David M. Gershenson> ;Gynecologic Oncology. 2019 Jun 1
22 citations
Prospective pilot trial with combination of propranolol with chemotherapy in patients with epithelial ovarian cancer and evaluation on circulating immune cell gene exp...
Lois M. Ramondetta, Wei Hu, Premal H. Thaker, Diana L. Urbauer, Gary B. Chisholm, Shannon N. Westin, Yunjie Sun, Nicole D. Fleming, Sunil K. Sahai, Alpa M. Nick, Jesus...> ;Gynecologic Oncology. 2019 Sep 1
36 citations
Prospective Validation of an Ex Vivo, Patient-Derived 3D Spheroid Model for Response Predictions in Newly Diagnosed Ovarian Cancer.
Stephen Shuford, Christine Wilhelm, Melissa Rayner, Ashley Elrod, Melissa Millard, Christina Mattingly, Alina Lotstein, Ashley M. Smith, Qi Jin Guo, Lauren O’Donnell, ...> ;Scientific Reports. 2019 Aug 1
12 citations
Comparison of patient reported symptom burden on an enhanced recovery after surgery (ERAS) care pathway in patients with ovarian cancer undergoing primary vs. interval...
Larissa A. Meyer, Qiuling Shi, Javier Lasala, Maria D. Iniesta, Huei Kai Lin, Alpa M. Nick, Loretta A. Williams, Charlotte C. Sun, Xin Shelley Wang, Karen H. Lu> ;Gynecologic Oncology. 2019 Mar 1
91 citations
Effect of an Enhanced Recovery After Surgery Program on Opioid Use and Patient-Reported Outcomes
Larissa A. Meyer, Javier Lasala, Maria D. Iniesta, Alpa M. Nick, Mark F. Munsell, Qiuling Shi, Xin Shelley Wang, Katherine E. Cain, Karen H. Lu> ;Obstetrics and Gynecology. 2018 Aug 1
9 citations
The influence of surgeon volume on outcomes after pelvic exenteration for a gynecologic cancer
Randa J. Jalloul, Alpa M. Nick, Mark F. Munsell, Shannon N. Westin, Michael Frumovitz, Pamela T. Soliman> ;Journal of Gynecologic Oncology. 2018 Apr 13
40 citations
Laparoscopic Surgical Algorithm to Triage the Timing of Tumor Reductive Surgery in Advanced Ovarian Cancer.
Nicole D. Fleming, Alpa M. Nick, Robert L. Coleman, Shannon N. Westin, Pamela T. Soliman, Bryan Fellman, Larissa A. Meyer, Kathleen M. Schmeler, Karen H. Lu, Anil K. Sood> ;Obstetrics and Gynecology. 2018 Jan 1
4 citations
Dual progestin therapy for fertility-sparing treatment of grade 2 endometrial adenocarcinoma.
Andreea M. Newtson, J.B. Pakish, Alpa M. Nick, Shannon N. Westin> ;Gynecologic Oncology Reports. 2017 Aug 8
4 citations
Vascular-Associated Muc4/Vwf Co-Localization in Human Conjunctival Malignant Melanoma Specimens-Tumor Metastasis by Migration?
Vinodh Kakkassery, Sibylle Winterhalter, Ann-Christin Nick, Stephanie C. Joachim, Antonia M. Joussen, Norbert Kociok> ;Current Eye Research. 2017 Jun 16
A comprehensive evaluation of different risk-assessment models to predict 30-day postoperative complications in gynaecologic patients undergoing surgery under an Enhan...
Iniesta, M. D., Salvo, G., Meyer, L. A., Lasala, J., Cain, K. E., Nick, A. M., Earles, T., Munsell, M. F., Ramirez, P. T.> ;Clinical nutrition ESPEN. 2017 May 23
Impact of an Enhanced Surgical Recovery Programme (ESRP) on postoperative renal function: Is euvolemia ideal for all or only a select few?
Lasala, J. D., Heir, J. S., Mena, G. E., Nick, A. M., Meyer, L. A., Iniesta, M. D., Munsell, M. F., Salvo, G., Cata, J. P., Ifeanyi, I., Gottumukkala, V., Cain, K. E.,...> ;Clinical nutrition ESPEN. 2017 May 23
Implementation of an Enhanced Surgical Recovery Programme (ESRP) in gynaecologic oncology: Has the development of a preoperative order set improved compliance for prev...
Lasala, J. D., Heir, J. S., Mena, G. E., Nick, A. M., Meyer, L. A., Iniesta, M. D., Munsell, M. F., Salvo, G., Cata, J. P., Ifeanyi, I., Gottumukkala, V., Cain, K. E.,...> ;Clinical nutrition ESPEN. 2017 May 23
Implementation of an Enhanced Surgical Recovery Programme (ESRP) in gynaecologic oncology: an approach for all ages or just for the young at heart?
Lasala, J. D., Heir, J. S., Mena, G. E., Nick, A. M., Meyer, L. A., Iniesta, M. D., Munsell, M. F., Salvo, G., Cata, J. P., Ramirez, P. T.> ;Clinical nutrition ESPEN. 2017 May 23
Bowel surgery in an Enhanced Surgical Recovery Programme (ESRP) for gynaecologic surgery: Is recovery still enhanced or do we need to take a step back?
Salvo, G., Iniesta, M. D., Lasala, J., Larissa, M. A., Nick, A. M., Cain, K. E., Mena, G. E., Munsell, M. F., Earles, T., Ramirez, P. T.> ;Clinical nutrition ESPEN. 2017 May 23
Correlation of Body Mass Index (BMI) and perioperative outcomes in patients on an Enhanced Surgical Recovery Programme (ESRP): Are obese patients at a disadvantage or ...
Salvo, G., Iniesta, M. D., Lasala, J., Meyer, L. A., Nick, A. M., Cain, K. E., Mena, G. E., Munsell, M. F., Earles, T., Ramirez, P. T.> ;Clinical nutrition ESPEN. 2017 May 23
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Journal Articles

Prospective Phase II Trial of Levonorgestrel Intrauterine Device: Non-Surgical Approach for Complex Atypical Hyperplasia and Early Endometrial Cancer
Shannon N Westin, Lois M Ramondetta, Kathleen M Schmeler, Pamela T Soliman, Nicole D Fleming, Jennifer K Burzawa, Alpa M Nick, Andrea M Milbourne, Diane C Bodurka, Rob..., American Journal of Obstetrics and Gynecology

Authored Content

Prospective Phase II Trial of Levonorgestrel Intrauterine Device: Non-Surgical Approach for Complex Atypical Hyperplasia and Early Endometrial CancerAugust 2020
Prospective Phase II Trial of Levonorgestrel Intrauterine Device: Non-Surgical Approach for Complex Atypical Hyperplasia and Early Endometrial CancerAugust 2020