Alvaro Pascual-Leone MD PhD

Neurophysiology, Dementia & Geriatrics

Medical Director, Deanna and Sidney Wolk Center for Memory Health - Hebrew SeniorLife Professor of Neurology, Harvard Medical School

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Hebrew SeniorLife1200 Centre StBoston, MA 02131
Phone+1 617-383-8600
Fax+1 289-271-4398

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Education & Training

University of MinnesotaResidency, Neurology, 1986 - 1990
Albert Ludwigs University Faculty of MedicineClass of 1985

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Certifications & Licensure

MA State Medical License 1997 - 2027
MN State Medical License 1988 - 1997
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 2 Certification Quality Data Center (QDC), Massachusetts eHealth Collaborative (MAeHC), 2012, 2014, 2016
CMS Meaningful Use Stage 1 Certification Online Medical Record, Beth Israel Deaconess Medical Center, 2012, 2014, 2016
CMS Meaningful Use Stage 2 Certification Online Medical Record, Beth Israel Deaconess Medical Center, 2012, 2014, 2016

Clinical Trials

tDCS and Physical Therapy in Stroke
COMPLETED
NA
Transcranial Magnetic Stimulation to Improve Speech in Aphasia
COMPLETED
PHASE1
rTMS for Motor and Mood Symptoms of Parkinson's Disease
COMPLETED
NA

Publications & Presentations

PubMed

Input-output curves demonstrate motor cortex hyperexcitability associated with cognitive impairment in Alzheimer's disease.
Julia H Cho, Brice Passera, Giacomo Bertazzoli, Recep A Ozdemir, Basma Gomaa
Neurobiology of Aging. 2026-12-01
Dissociating mechanisms of spatial suppression and summation in human visual cortical regions MT/V5: a transcranial Direct Current Stimulation (tDCS) study and clinica...
Federica Contò, Sara Agosta, Duje Tadin, Alvaro Pascual-Leone, Lorella Battelli
International Review of Psychiatry. 2026-09-01
Assessing the efficacy and reproducibility of four common repetitive transcranial magnetic stimulation protocols: A sham-controled study.
Brice Passera, Peter J Fried, Justine Magnuson, Stephanie S Buss, Alvaro Pascual-Leone
Imaging Neuroscience. 2026-07-16

Journal Articles

Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis
Brian J Wainger, Nicholas J Maragakis, Richard Bedlack, Namita A Goyal, Seward B Rutkove, Michael H Rivner, Stephen A Goutman, Shafeeq S Ladha, Elizabeth A Mauricio, R..., JAMA Neurology

Lectures

An Introduction to the Clinical Practice of Transcranial Magnetic Stimulation
Harvard Medical School ,Department Of Continuing Education, Boston, Massachusetts - 6/24/2013
Intensive Course in Transcranial Magnetic Stimulation
Harvard Medical School ,Department Of Continuing Education, Boston, Massachusetts - 6/24/2013
Introduction to Transcranial Direct Current Stimulation in Neuropsychiatric Research
Harvard Medical School, Boston, Massachusetts - 11/3/2012

Press Mentions

Anywhere for Health Systems™ Delivers Clinical-Grade Cognitive Assessments RemotelyMarch 18th, 2025
Linus Health Achieves Landmark Research Recognition Across Peer-Reviewed Medical and Scientific JournalsMarch 5th, 2025
Rapidly Progressive Dementia: Reasons for a Sudden Worsening of Dementia SymptomsJanuary 30th, 2025

Grant Support

Multifocal transcranial current stimulation for cognitive and motor dysfunction in dementiaHEBREW REHABILITATION CENTER FOR AGED2022–2027
Multifocal transcranial current stimulation for cognitive and motor dysfunction in dementiaHEBREW REHABILITATION CENTER FOR AGED2022–2027

Professional Memberships

American Academy of Neurology - AAN
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