AlyssaTReddyMD

Pediatrics • San Francisco, CA

Child Neurology

Professor, Pediatrics, University of Alabama School of Medicine

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Office
1825 4th St
San Francisco, CA 94143
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Summary

I am a board certified Child Neurologist with expertise in Pediatric Neuro-Oncology

Education & Training

University of Alabama Medical CenterFellowship, Child Neurology, 1995 - 1998
University of Alabama Medical CenterResidency, Pediatrics, 1993 - 1995
University of Alabama School of MedicineClass of 1993

Certifications & Licensure

CA State Medical License 2018 - 2025
AL State Medical License Active through 2018
American Board of Psychiatry and Neurology Neurology with Special Qualification in Child Neurology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014

Clinical Trials

Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma Start of enrollment: 2001 Oct 18
Active, not recruiting
Phase 3
Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors Start of enrollment: 2004 Mar 25
Recruiting
Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer Start of enrollment: 2007 May 01
Completed
Phase 3
Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET Start of enrollment: 2007 Mar 26
Active, not recruiting
Phase 3
Combination Chemotherapy, Autologous Stem Cell Transplant, and/or Radiation Therapy in Treating Young Patients With Extraocular Retinoblastoma Start of enrollment: 2008 Feb 04
Active, not recruiting
Phase 3
Combination Chemotherapy, Radiation Therapy, and an Autologous Peripheral Blood Stem Cell Transplant in Treating Young Patients With Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System Start of enrollment: 2008 Dec 08
Active, not recruiting
Phase 3
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies Start of enrollment: 2008 Jul 17
Recruiting
Neuropsychological and Behavioral Testing in Younger Patients With Cancer Start of enrollment: 2009 Feb 27
Recruiting
Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer Start of enrollment: 2003 Oct 13
Completed
Study of Kidney Tumors in Younger Patients Start of enrollment: 2006 Feb 27
Recruiting
Collecting and Storing Biological Samples From Patients With Ewing Sarcoma Start of enrollment: 2008 Feb 04
Completed
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma Start of enrollment: 2000 Nov 06
Recruiting
Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma Start of enrollment: 1999 Mar 15
Completed
Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors Start of enrollment: 2004 Feb 16
Completed
Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor Start of enrollment: 2009 Jul 13
Active, not recruiting
Phase 3
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 14
Active, not recruiting
Phase 3
Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma Start of enrollment: 2010 May 07
Active, not recruiting
Phase 3
Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Start of enrollment: 2010 Aug 09
Completed
Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin Start of enrollment: 2010 Oct 04
Active, not recruiting
Phase 1
Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma Start of enrollment: 2010 Aug 09
Active, not recruiting
Phase 3
Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors Start of enrollment: 2010 Nov 22
Completed
Phase 2
Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Start of enrollment: 2010 Nov 22
Active, not recruiting
Phase 3
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia Start of enrollment: 2011 Apr 04
Completed
Phase 3
Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Start of enrollment: 2011 Jun 20
Active, not recruiting
Phase 3
Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor Start of enrollment: 2011 Aug 01
Completed
Phase 2
A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum Start of enrollment: 2012 Feb 01
Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission Start of enrollment: 2012 Feb 21
Active, not recruiting
Phase 3
Intergroup Trial for Children or Adolescents With B-Cell NHL or B-AL: Evaluation of Rituximab Efficacy and Safety in High Risk Patients Start of enrollment: 2012 Jun 01
Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors Start of enrollment: 2012 Jun 27
Active, not recruiting
Phase 2
Brentuximab Vedotin and Gemcitabine Hydrochloride in Treating Younger Patients With Relapsed or Refractory Hodgkin Lymphoma Start of enrollment: 2013 Jan 31
Completed
Phase 1, Phase 2
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment Start of enrollment: 2014 Mar 05
Recruiting
Busulfan, Cyclophosphamide, and Melphalan or Busulfan and Fludarabine Phosphate Before Donor Hematopoietic Cell Transplant in Treating Younger Patients With Juvenile Myelomonocytic Leukemia Start of enrollment: 2013 Jun 24
Completed
Phase 2
Open Label, Phase II Study to Evaluate Efficacy and Safety of Oral Nilotinib in Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia (CML) Pediatric Patients. Start of enrollment: 2013 Aug 20
Completed
Phase 2
Brentuximab Vedotin or Crizotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II-IV Anaplastic Large Cell Lymphoma Start of enrollment: 2013 Nov 13
Active, not recruiting
Phase 2
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 01
A Study of Ramucirumab (LY3009806) in Children With Refractory Solid Tumors Start of enrollment: 2015 Dec 11
Completed
Phase 1
Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers Start of enrollment: 2020 Aug 14
Recruiting
Phase 2
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

9 citations
Multiplatform molecular analyses refine classification of gliomas arising in patients with neurofibromatosis type 1.
Calixto-Hope G Lucas, Emily A Sloan, Rohit Gupta, Jasper Wu, Drew Pratt, Harish N Vasudevan, Ajay Ravindranathan, Jairo Barreto, Erik A Williams, Anny Shai, Nicholas S...> ;Acta Neuropathologica. 2022 Oct 1
10 citations
Clinical phenotypes and prognostic features of embryonal tumours with multi-layered rosettes: a Rare Brain Tumor Registry study
Sara Khan, Palma Solano-Paez, Tannu Suwal, Mei Lu, Salma Al-Karmi, Ben Ho, Iqra Mumal, Mary Shago, Lindsey Hoffman, Andrew Dodgshun, Sumihito Nobusawa, Uri Tabori, Ute...> ;The Lancet. Child & Adolescent Health. 2021 Sep 29
11 citations
Diffuse hemispheric glioma, H3 G34-mutant: Genomic landscape of a new tumor entity and prospects for targeted therapy
Calixto-Hope G Lucas, Alyssa Reddy, Jennie Taylor, Nancy Ann Oberheim Bush, Jennifer Clarke, Susan M. Chang, Nalin Gupta, Mitchel S. Berger, Arie Perry, Joanna J. Phil...> ;Neuro-Oncology. 2021 Nov 2
Multiple Tumor-Associated Intracranial Aneurysms Adjacent to a Suprasellar Germ Cell Tumor: Case Report and Review of Literature.
John K. Yue, Taemin Oh, Ethan A. Winkler, Alex Y. Lu, Steven W. Hetts, Elizabeth P Young, Alyssa Reddy, Christine K. Fox, Adib A. Abla, Jarod L. Roland> ;Pediatric Neurosurgery. 2021 Jan 1
25 citations
Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance.
Carol Durno, Ayse Bahar Ercan, Vanessa Bianchi, Melissa Edwards, Melyssa Aronson, Melissa Galati, Eshetu G. Atenafu, Gadi Abebe-Campino, Abeer Al-Battashi, Musa Alharb...> ;Journal of Clinical Oncology. 2021 May 4
35 citations
DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells.
Jiil Chung, Yosef E. Maruvka, Sumedha Sudhaman, Jacalyn Kelly, Nicholas J. Haradhvala, Vanessa Bianchi, Melissa Edwards, Victoria J. Forster, Nuno Miguel Nunes, Meliss...> ;Cancer Discovery. 2021 May 1
43 citations
Intracranial mesenchymal tumor with FET-CREB fusion - a unifying diagnosis for the spectrum of intracranial myxoid mesenchymal tumors and angiomatoid fibrous histiocyt...
Emily A. Sloan, Jason Chiang, Javier Villanueva-Meyer, Sanda Alexandrescu, Jennifer M. Eschbacher, Wesley Wang, Manuela Mafra, Nasir Ud Din, Emily Carr-Boyd, Michael W...> ;Brain Pathology. 2021 Jan 28
38 citations
A phase II study of continuous oral mTOR inhibitor everolimus for recurrent, radiographic-progressive neurofibromatosis type 1-associated pediatric low-grade glioma: a...
Nicole J. Ullrich, Sanjay P. Prabhu, Alyssa Reddy, Michael Fisher, Roger J. Packer, Stewart Goldman, Nathan Robison, David H. Gutmann, David Viskochil, Jeffrey C. Alle...> ;Neuro-Oncology. 2020 Oct 14
30 citations
Comprehensive analysis of diverse low-grade neuroepithelial tumors with FGFR1 alterations reveals a distinct molecular signature of rosette-forming glioneuronal tumor
Calixto-Hope G Lucas, Rohit Gupta, Pamela Doo, Julieann C. Lee, Cathryn R. Cadwell, Biswarathan Ramani, Jeffrey W. Hofmann, Emily A. Sloan, Bette K. Kleinschmidt-DeMas...> ;Acta Neuropathologica Communications. 2020 Aug 28
2 citations
Reply to S.A. Upadhyaya
Alyssa Reddy, Mark Krailo, Allen Buxton, Douglas Strother, Annie Huang, Tianni Zhou, Alexander R. Judkins, Peter C. Burger, Ian F. Pollack, Chris Williams-Hughes, Mary...> ;Journal of Clinical Oncology. 2020 Jul 30
19 citations
Advancing biology-based therapeutic approaches for atypical teratoid rhabdoid tumors.
Lindsey Hoffman, Elizabeth Anne Richardson, Ben Ho, Ashley Margol, Alyssa Reddy, Lucie Lafay-Cousin, Susan N. Chi, Irene Slavc, Alexander R. Judkins, Martin Hasselblat...> ;Neuro-Oncology. 2020 Jul 7
41 citations
Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition.
Gourish Mondal, Julieann C. Lee, Ajay Ravindranathan, Javier Villanueva-Meyer, Quynh T. Tran, Sariah Allen, Jairo Barreto, Rohit Gupta, Pamela Doo, Jessica Van Ziffle,...> ;Acta Neuropathologica. 2020 Apr 17
13 citations
Gliomas arising in the setting of Li-Fraumeni syndrome stratify into two molecular subgroups with divergent clinicopathologic features.
Emily A. Sloan, Stephanie Hilz, Rohit Gupta, Cathryn R. Cadwell, Biswarathan Ramani, Jeffrey W. Hofmann, Cassie Kline, Anu Banerjee, Alyssa Reddy, Nancy Ann Oberheim B...> ;Acta Neuropathologica. 2020 Mar 10
3 citations
Treatment of pediatric high-grade central nervous system tumors with high-dose methotrexate in combination with multiagent chemotherapy: A single-institution experience.
Joshua D. Bernstock, Elizabeth Alva, Joshua L. Cohen, Mina Lobbous, Gustavo Chagoya, Galal A. Elsayed, Brent A. Orr, Curtis J. Rozzelle, Brandon G. Rocque, Jeffrey P. ...> ;Pediatric Blood & Cancer. 2020 Mar 1
77 citations
Efficacy of High-Dose Chemotherapy and Three-Dimensional Conformal Radiation for Atypical Teratoid/Rhabdoid Tumor: A Report From the Children's Oncology Group Trial AC...
Alyssa Reddy, Douglas Strother, Alexander R. Judkins, Peter C. Burger, Ian F. Pollack, Mark Krailo, Allen Buxton, Chris Williams-Hughes, Maryam Fouladi, Anita Mahajan,...> ;Journal of Clinical Oncology. 2020 Feb 27
16 citations
Recurrent non-canonical histone H3 mutations in spinal cord diffuse gliomas
Emily A. Sloan, Tabitha Cooney, Nancy Ann Oberheim Bush, Robin A. Buerki, Jennie Taylor, Jennifer Clarke, Joseph Torkildson, Cassie Kline, Alyssa Reddy, Sabine Mueller...> ;Acta Neuropathologica. 2019 Sep 12
58 citations
A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor
Patrick Sin-Chan, Iqra Mumal, Tannu Suwal, Ben Ho, Xiaolian Fan, Irtisha Singh, Yuchen Du, Mei Lu, Neilket Patel, Jonathon Torchia, Dean Popovski, Maryam Fouladi, Paul...> ;Cancer Cell. 2019 Jul 8
2 citations
Complete durable response of a pediatric anaplastic oligodendroglioma to temozolomide alone: Case report and review of literature
Caryn E. Sorge, Rong Li, Sumit Singh, Alyssa Reddy, David A. Solomon, Arie Perry, Gregory K. Friedman> ;Pediatric Blood & Cancer. 2017 Jul 11
Rationale and Design of a Phase I Clinical Trial to Evaluate HSV G207 Alone or with a Single Radiation Dose in Children with Progressive or Recurrent Malignant Suprate...
Waters, A. M., Johnston, J. M., Reddy, A. T., Fiveash, J., Madan-Swain, A., Kachurak, K., Bag, A. K., Gillespie, G. Y., Markert, J. M., Friedman, G. K.> ;Human gene therapy. Clinical development. 2017 Mar 4
40 citations
Rationale and Design of a Phase 1 Clinical Trial to Evaluate HSV G207 Alone or with a Single Radiation Dose in Children with Progressive or Recurrent Malignant Suprate...
Alicia M. Waters, James M. Johnston, Alyssa Reddy, John B. Fiveash, Avi Madan-Swain, Kara Kachurak, Asim K. Bag, G. Yancey Gillespie, James M. Markert, Gregory K. Frie...> ;Human Gene Therapy. Clinical Development. 2017 Mar 1
166 citations
Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors
Jonathon Torchia, Brian Golbourn, Shengrui Feng, King Ching Ho, Patrick Sin-Chan, Alexandre Vasiljevic, Joseph D. Norman, Paul Guilhamon, Livia Garzia, Natalia R. Agam...> ;Cancer Cell. 2016 Dec 12
573 citations
Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency
Eric Bouffet, Valérie Larouche, Brittany Campbell, Daniele Merico, Richard de Borja, Melyssa Aronson, Carol Durno, Joerg Krueger, Vanja Cabric, Vijay Ramaswamy, Natali...> ;Journal of Clinical Oncology. 2016 Sep 27
Molecular Pathology: SC18-1 INTERESTING CASE - ACTIONABLE MUTATION IN A CASE WITH A RECURRENT PLEOMORPHIC XANTHOASTROCYTOMA WITH ANAPLASTIC FEATURES.
Harada, S.,Fallon, K. B.,Reddy, A.,Nabors, L. B.> ;Pathology. 2014 Sep 05
72 citations
Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neur...
Brigitte C. Widemann, Eva Dombi, Andrea Gillespie, Pamela L. Wolters, Jean B. Belasco, Stewart Goldman, Bruce R. Korf, Jeffrey Solomon, Staci Martin, Wanda L. Salzer, ...> ;Neuro-Oncology. 2014 May 1
Epilepsy surgery in bifrontal injury from prior craniopharyngioma resections
Monisha Goyal, Matthew D. Thompson, Alyssa Reddy, Allan Harrison, Jeffrey P. Blount> ;Epilepsy & Behavior Case Reports. 2014 Jan 1
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Press Mentions

Childhood Cancer Research at UAB Continues with Grants from St. Baldrick’s FoundationJuly 25th, 2017
UAB to Bring Proton Therapy for Advanced Cancer Treatment to BirminghamFebruary 16th, 2017