AmandaCatherineWintersMD

PubMed

• 1 citations
  Multi-gene measurable residual disease assessed by digital polymerase chain reaction has clinical and biological utility in acute myeloid leukemia patients receiving v...
  Minhajuddin, M., Stevens, B., Bosma, G., Abbott, D., Miltgen, N., Yuan, J., Treece, A., Jordan, C., Winters, A., Major, A., Siegele, B., Ewalt, M., Gutman, J., Pollyea...> ;Haematologica. 2023 Dec 14
• Targeting Acute Myeloid Leukemia Stem Cells Through Perturbation of Mitochondrial Calcium.
  Anagha Inguva Sheth, Krysta Engel, Hunter Tolison, Mark J Althoff, Maria L Amaya, Anna Krug, Tracy Young, Shanshan Pei, Sweta B Patel, Mohammad Minhajuddin, Amanda Win...> ;Biorxiv. 2023 Oct 3
• 2 citations
  Digital polymerase chain reaction strategies for accurate and precise detection of vector copy number in chimeric antigen receptor T-cell products.
  Lindsey A Murphy, Russell C Marians, Kristen Miller, Matthew D Brenton, Rebecca L V Mallo, M Eric Kohler, Terry J Fry, Amanda C Winters> ;Cytotherapy. 2023 Jan 1
• Time to transplantation and pediatric acute myeloid leukemia outcomes.
  Lindsey A Murphy, Kristen Miller, Amanda C Winters, Anna R K Franklin, Michael R Verneris, Amy K Keating> ;Bone Marrow Transplantation. 2023 Mar 1
• 20 citations
  Outcomes Are Similar After Allogeneic Hematopoietic Stem Cell Transplant for Newly Diagnosed Acute Myeloid Leukemia Patients who Received Venetoclax + Azacitidine Vers...
  Amanda C Winters, Grace Bosma, Diana Abbott, Mohd Minhajuddin, Craig Jordan, Daniel A Pollyea, Jonathan A Gutman> ;Transplantation and Cellular Therapy. 2022 Oct 1
• 4 citations
  N-terminus DUX4-immunohistochemistry is a reliable methodology for the diagnosis of DUX4-fused B-lymphoblastic leukemia/lymphoma (N-terminus DUX4 IHC for DUX4-fused B-...
  Bradford J Siegele, Anat O Stemmer-Rachamimov, Henrik Lilljebjorn, Thoas Fioretos, Amanda C Winters, Paola Dal Cin, Amy Treece, Alisa Gaskell, Valentina Nardi> ;Genes, Chromosomes & Cancer. 2022 Aug 1
• 36 citations
  Venetoclax and azacitidine followed by allogeneic transplant results in excellent outcomes and may improve outcomes versus maintenance therapy among newly diagnosed AM...
  Daniel A. Pollyea, Amanda Winters, Christine McMahon, Marc Schwartz, Craig T. Jordan, Rachel Rabinovitch, Diana Abbott, Clayton A. Smith, Jonathan A. Gutman> ;Bone Marrow Transplantation. 2021 Oct 13
• 73 citations
  Venetoclax and Azacitidine Compared to Induction Chemotherapy for Newly Diagnosed Patients with Acute Myeloid Leukemia.
  Evan Cherry, Diana Abbott, Maria L. Amaya, Christine McMahon, Marc Schwartz, Julie Rosser, Audrey Sato, Jeffrey Schowinsky, Anagha Inguva, Mohd Minhajuddin, Shanshan P...> ;Blood Advances. 2021 Oct 5
• 46 citations
  The STAT3-MYC Axis Promotes Survival of Leukemia Stem Cells by Regulating SLC1A5 and Oxidative Phosphorylation.
  Maria L. Amaya, Anagha Inguva, Shanshan Pei, Courtney L. Jones, Anna Krug, Haobin Ye, Mohammad Minhajuddin, Amanda Winters, Steffanie L. Furtek, Fabia Gamboni, Brett M...> ;Blood. 2021 Sep 15
• 6 citations
  The propriety of upgrading responses to venetoclax + azacitidine in newly diagnosed patients with acute myeloid leukemia
  Diana Abbott, Evan Cherry, Maria L. Amaya, Christine McMahon, Marc Schwartz, Amanda Winters, Jeffrey Schowinsky, Craig T. Jordan, Clayton A. Smith, Jonathan A. Gutman,...> ;Leukemia & Lymphoma. 2021 May 12
• 123 citations
  Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells
  Brett M. Stevens, Courtney L. Jones, Daniel A. Pollyea, Rachel Culp-Hill, Angelo D'Alessandro, Amanda Winters, Anna Krug, Diana Abbott, Madeline Goosman, Shanshan Pei,...> ;Nature Cancer. 2020 Oct 26
• Sequential azacitidine and lenalidomide for patients with relapsed and refractory acute myeloid leukemia: Clinical results and predictive modeling using computational ...
  Stevens, B.,Winters, A.,Gutman, J. A.,Fullerton, A.,Hemenway, G.,Schatz, D.,Miltgen, N.,Wei, Q.,Abbasi, T.,Vali, S.,Singh, N. K.,Drusbosky, L.,Cogle, C. R.,Hammes, A.,...> ;Leuk. Res.. 2019 Apr 23
• Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells.
  Ye, H.,Adane, B.,Khan, N.,Alexeev, E.,Nusbacher, N.,Minhajuddin, M.,Stevens, B. M.,Winters, A. C.,Lin, X.,Ashton, J. M.,Purev, E.,Xing, L.,Pollyea, D. A.,Lozupone, C. ...> ;Cancer Cell. 1900 Jan 01
• Metastatic angiosarcoma arising in malignant peripheral nerve sheath tumor in a young patient with neurofibromatosis type 1.
  Winters AC, Black JO, Cost CR> ;Pediatr Blood Cancer. 2017 Dec
• MLL-Rearranged Leukemias-An Update on Science and Clinical Approaches.
  Winters AC, Bernt KM> ;Front Pediatr. 2017
• Vitamin K Deficiency Presenting in an Infant with an Anterior Mediastinal Mass: A Case Report and Review of the Literature.
  Palau MA, Winters A, Liang X, Nuss R, Niermeyer S, Gossling M, Wright C> ;Case Rep Pediatr. 2017
• A postmenopausal woman with gross cystic disease fluid protein-15 and estrogen receptor-positive recurrence of papillary thyroid cancer.
  Winters, A.,Friedlander, P.,Jaffe, B. M.,Khalek, M. A.,Moroz, K.,Kandil, E.> ;Thyroid. 2010 Nov 09
• 7 citations
  Molecular targeting of MLL-rearranged leukemia cell lines with the synthetic peptide PFWT synergistically enhances the cytotoxic effect of established chemotherapeutic...
  Amanda Winters, Nisha N. Barretto, Charles S. Hemenway> ;Leukemia Research. 2009 Jul 1
• 19 citations
  The AF4-mimetic peptide, PFWT, induces necrotic cell death in MV4-11 leukemia cells
  Christine M. Palermo, Amanda Winters, Charles S. Hemenway> ;Leukemia Research. 2008 Apr 1
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Abstracts/Posters

• Outcomes Following Allogeneic Stem Cell Transplantation for AML in First Completion Remission Are Comparable between MRD Negative Patients and MRD Positive Patients Re...
  Amanda Winters, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019

Lectures

• Tracking of AML-Associated Mutations Via Droplet Digital PCR Is Predictive of Outcomes Post-Transplant 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• WT1 and BCORL1 Identified By Computational Biology Modeling Analysis of Patient Genomics Are Novel Predictors of Response to Azacitidine (AZA) and Lenalidomide (LEN) T... 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018