AmitRMajithiaMD

PubMed

• 2 citations
  Human gain-of-function variants in HNF1A confer protection from diabetes but independently increase hepatic secretion of atherogenic lipoproteins.
  Natalie DeForest, Babu Kavitha, Siqi Hu, Roi Isaac, Lynne Krohn, Minxian Wang, Xiaomi Du, Camila De Arruda Saldanha, Jenny Gylys, Edoardo Merli, Ruben Abagyan, Laeya N...> ;Cell Genomics. 2023 Jul 12
• Glycocalyx engineering with heparan sulfate mimetics attenuates Wnt activity during adipogenesis to promote glucose uptake and metabolism.
  Greg W Trieger, Ariane R Pessentheiner, Sean C Purcell, Courtney R Green, Natalie DeForest, Karl Willert, Amit R Majithia, Christian M Metallo, Kamil Godula, Philip L ...> ;The Journal of Biological Chemistry. 2023 May 1
• 1 citations
  A seven-transmembrane protein-TM7SF3, resides in nuclear speckles and regulates alternative splicing.
  Roi Isaac, Yaron Vinik, Martin Mikl, Shani Nadav-Eliyahu, Hadas Shatz-Azoulay, Adi Yaakobi, Natalie DeForest, Amit R Majithia, Nicholas J G Webster, Yaron Shav-Tal, Ey...> ;Iscience. 2022 Nov 18
• 7 citations
  Accuracy and Glycemic Efficacy of Continuous Glucose Monitors in Critically Ill COVID-19 Patients: A Retrospective Study.
  Schafer Boeder, Emily Kobayashi, Gautam Ramesh, Brittany Serences, Kristen Kulasa, Amit R Majithia> ;Journal of Diabetes Science and Technology. 2023 May 1
• 19 citations
  Genetics of Type 2 Diabetes: Implications from Large-Scale Studies.
  Natalie DeForest, Amit R Majithia> ;Current Diabetes Reports. 2022 May 1
• 1 citations
  Medication Optimization Among People With Type 2 Diabetes Participating in a Continuous Glucose Monitoring-Driven Virtual Care Program: Prospective Study.
  Amit R Majithia, David M Erani, Coco M Kusiak, Jennifer E Layne, Amy Armento Lee, Francis R Colangelo, Robert J Romanelli, Scott Robertson, Shayla M Brown, Ronald F Di...> ;JMIR Formative Research. 2022 Apr 5
• 9 citations
  Human Genetics to Identify Therapeutic Targets for NAFLD: Challenges and Opportunities.
  Xiaomi Du, Natalie DeForest, Amit R Majithia> ;Frontiers in Endocrinology. 2021 Jan 1
• 53 citations
  Remote Application and Use of Real-Time Continuous Glucose Monitoring by Adults with Type 2 Diabetes in a Virtual Diabetes Clinic.
  Richard M. Bergenstal, Jennifer E. Layne, Howard Zisser, Robert A. Gabbay, Nathan A. Barleen, Amy Armento Lee, Amit R. Majithia, Christopher G. Parkin, Ronald F. Dixon> ;Diabetes Technology & Therapeutics. 2021 Jan 28
• 34 citations
  Glycemic Outcomes in Adults With Type 2 Diabetes Participating in a Continuous Glucose Monitor–Driven Virtual Diabetes Clinic: Prospective Trial
  Amit R. Majithia, Coco Kusiak, Amy Armento Lee, Francis R. Colangelo, Robert J. Romanelli, Scott Robertson, David P. Miller, David M Erani, Jennifer E. Layne, Ronald F...> ;Journal of Medical Internet Research. 2020 Aug 28
• 13 citations
  Thousands of missing variants in the UK Biobank are recoverable by genome realignment.
  Tongqiu Jia, Brenton Munson, Hana Lango Allen, Trey Ideker, Amit R. Majithia> ;Annals of Human Genetics. 2020 May 1
• 28 citations
  Gene family information facilitates variant interpretation and identification of disease-associated genes in neurodevelopmental disorders.
  Dennis Lal, Patrick May, Eduardo Pérez-Palma, Kaitlin E. Samocha, Jack A. Kosmicki, Elise B. Robinson, Rikke S. Møller, Roland Krause, Peter Nürnberg, Sarah Weckhuysen...> ;Genome Medicine. 2020 Mar 17
• 9 citations
  Integrated actions of mTOR complexes 1 and 2 for growth and development of Dictyostelium.
  Pundrik Jaiswal, Amit R. Majithia, Daniel Rösel, Xin-Hua Liao, Taruna Khurana, Alan R. Kimmel> ;The International Journal of Developmental Biology. 2019 Jan 1
• 44 citations
  A Virtual Type 2 Diabetes Clinic Using Continuous Glucose Monitoring and Endocrinology Visits
  Ronald F. Dixon, Howard Zisser, Jennifer E. Layne, Nathan A. Barleen, David P. Miller, Daniel P Moloney, Amit R. Majithia, Robert A. Gabbay, Josh Riff> ;Journal of Diabetes Science and Technology. 2020 Sep 1
• 10 citations
  Discovering metabolic disease gene interactions by correlated effects on cellular morphology.
  Yang Jiao, Umer Ahmed, M.F. Michelle Sim, Andrea Bejar, Xiaolan Zhang, Mesbah Uddin Talukder, Robert H. Rice, Jason Flannick, Anna I. Podgornaia, Dermot F. Reilly, Jes...> ;Molecular Metabolism. 2019 Jun 1
• 10 citations
  Natural helix 9 mutants of PPARγ differently affect its transcriptional activity
  Marjoleine F. Broekema, Maarten P.G. Massink, Cinzia Donato, Joep de Ligt, Joerg Schaarschmidt, Anouska Borgman, Marieke G. Schooneman, Diana Melchers, Martin N. Gerdi...> ;Molecular Metabolism. 2019 Feb 1
• 25 citations
  A Pharmacogenetic Approach to the Treatment of Patients With PPARG Mutations.
  Maura Agostini, Erik Schoenmakers, Junaid Beig, Louise Fairall, Istvan Szatmari, Odelia Rajanayagam, Frederick W. Muskett, Claire Adams, A. David Marais, Stephen O'Rah...> ;Diabetes. 2018 Jun 1
• 5 citations
  Rate of Change of Premeal Glucose Measured by Continuous Glucose Monitoring Predicts Postmeal Glycemic Excursions in Patients With Type 1 Diabetes: Implications for Th...
  Amit R. Majithia, Alexander B. Wiltschko, Hui Zheng, Geoffrey A. Walford, David M. Nathan> ;Journal of Diabetes Science and Technology. 2018 Jan 1
• 148 citations
  Prospective functional classification of all possible missense variants in PPARG
  Amit R. Majithia, Ben Tsuda, Maura Agostini, Keerthana Gnanapradeepan, Robert H. Rice, Gina M. Peloso, Kashyap A. Patel, Xiaolan Zhang, Marjoleine F. Broekema, Nick Pa...> ;Nature Genetics. 2016 Oct 17
• 118 citations
  IGF2BP2/IMP2 Deficient Mice Resist Obesity through enhanced translation of Ucp1 mRNA and other mRNAs encoding Mitochondrial Proteins
  Ning Dai, Liping Zhao, Diedra M. Wrighting, Dana Kramer, Amit R. Majithia, Yanqun Wang, Valentin Cracan, Diego Borges-Rivera, Vamsi K. Mootha, Matthias Nahrendorf, Dav...> ;Cell Metabolism. 2015 Apr 7
• 126 citations
  Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes
  Amit R. Majithia, Jason Flannick, P Shahinian, Michael H. Guo, Bray M-A., Pierre Fontanillas, S. Gabriel, Nhgri Jhs, Evan D. Rosen, David Altshuler> ;Proceedings of the National Academy of Sciences of the United States of America. 2014 Sep 9
• 29 citations
  TOR complex 2 (TORC2) in Dictyostelium suppresses phagocytic nutrient capture independently of TORC1-mediated nutrient sensing
  Daniel Rösel, Taruna Khurana, Amit R. Majithia, Xiuli Huang, Ramanath Bhandari, Alan R. Kimmel> ;Journal of Cell Science. 2012 Jan 1
• 17 citations
  Association of the SLC30A8 missense polymorphism R325W with proinsulin levels at baseline and after lifestyle, metformin or troglitazone intervention in the Diabetes P...
  Amit R. Majithia, Kathleen A. Jablonski, Jarred B. McAteer, Kieren J. Mather, Ronald B. Goldberg, Steven E. Kahn, Jose C. Florez> ;Diabetologia. 2011 Jul 21
• 15 citations
  Combinatorial cell-specific regulation of GSK3 directs cell differentiation and polarity in Dictyostelium.
  Leung Kim, Joseph Brzostowski, Amit R. Majithia, Nam-Sihk Lee, Vanessa C. McMains, Alan R. Kimmel> ;Development. 2011 Feb 1
• 11 citations
  Clinical translation of genetic predictors for type 2 diabetes.
  Amit R. Majithia, Jose C. Florez> ;Current Opinion in Endocrinology, Diabetes, and Obesity. 2009 Apr 1
• 80 citations
  Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism.
  Xin-Hua Liao, Amit R. Majithia, Xiuli Huang, Alan R. Kimmel> ;Amino Acids. 2008 Jul 24
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