AnaM.IbradoMD

PubMed

• 10 citations
  Phase I and pharmacologic study of a 3-hour infusion of paclitaxel followed by cisplatinum and 5-fluorouracil in patients with advanced solid tumors.
  Kapil N. Bhalla, G. N. Kumar, U. Kristina Walle, Ana Maria Ibrado, Tahir Javed, Robert K. Stuart, Carolyn E. Reed, Susan G. Arbuck, Thomas Walle> ;Clinical Cancer Research. 1999 Jul 1
• 55 citations
  Temporal relationship of CDK1 activation and mitotic arrest to cytosolic accumulation of cytochrome C and caspase-3 activity during Taxol-induced apoptosis of human AM...
  Ana Maria Ibrado, Caryn Naekyung Kim, Kapil N. Bhalla> ;Leukemia. 1998 Jan 1
• 222 citations
  Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis.
  Caryn Naekyung Kim, Xiaodong Wang, Yue Huang, Ana Maria Ibrado, Linda Liu, Guofu Fang, Kapil N. Bhalla> ;Cancer Research. 1997 Aug 1
• 98 citations
  Bcl-xL overexpression inhibits progression of molecular events leading to paclitaxel-induced apoptosis of human acute myeloid leukemia HL-60 cells.
  Ana Maria Ibrado, Linda Liu, Kapil N. Bhalla> ;Cancer Research. 1997 Mar 15
• 4089 citations
  Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked
  Jie Yang, Xuesong Liu, Kapil N. Bhalla, Caryn Naekyung Kim, Ana Maria Ibrado, Jiyang Cai, Tsung I. Peng, Dean P. Jones, Xiaodong Wang> ;Science. 1997 Feb 21
• 129 citations
  Estrogen increases intracellular p26Bcl-2 to p21Bax ratios and inhibits taxol-induced apoptosis of human breast cancer MCF-7 cells
  Yue Huang, Swapan Ray, John C. Reed, Ana Maria Ibrado, Caroline Tang, Amir Nawabi, Kapil N. Bhalla> ;Breast Cancer Research and Treatment. 1997 Feb 11
• 93 citations
  Co-expression of several molecular mechanisms of multidrug resistance and their significance for paclitaxel cytotoxicity in human AML HL-60 cells.
  Yue Huang, Ana Maria Ibrado, John C. Reed, G. Bullock, S. Ray, Caroline Tang, Kapil N. Bhalla> ;Leukemia. 1997 Jan 1
• 51 citations
  Enforced expression of Bcl-x(S) induces differentiation and sensitizes chronic myelogenous leukemia-blast crisis K562 cells to 1-β-D- arabinofuranosylcytosine-mediated...
  Swapan Ray, Gloria Bullock, Gabriel Núñez, Caroline Tang, Ana Maria Ibrado, Yue Huang, Kapil N. Bhalla> ;Cell Growth & Differentiation. 1996 Dec 1
• 137 citations
  Overexpression of Bcl-2 or Bcl-xL Inhibits Ara-C-induced CPP32/Yama Protease Activity and Apoptosis of Human Acute Myelogenous Leukemia HL-60 Cells
  Ana Maria Ibrado, Yue Huang, Guofu Fang, Linda Liu, Kapil N. Bhalla> ;Cancer Research. 1996 Oct 15
• 74 citations
  Bcl-xL overexpression inhibits taxol-induced Yama protease activity and apoptosis.
  Ana Maria Ibrado, Yue Huang, Guofu Fang, Kapil N. Bhalla> ;Cell Growth & Differentiation. 1996 Aug 1
• 23 citations
  Intracellular metabolism of Ara-C and resulting DNA fragmentation and apoptosis of human AML HL-60 cells possessing disparate levels of Bcl-2 protein
  G. Bullock, Swapan K. Ray, John C. Reed, S. Krajewski, Ana Maria Ibrado, Yue Huang, Kapil N. Bhalla> ;Leukemia. 1996 Jan 1
• 20 citations
  Effects of modulators of protein kinases on taxol-induced apoptosis of human leukemic cells possessing disparate levels of p26BCL-2 protein.
  Vidya Ponnathpur, Ana Maria Ibrado, John C. Reed, Swapan K. Ray, Yue Huang, Sally E. Self, Gloria Bullock, Amir Nawabi, Kapil N. Bhalla> ;Clinical Cancer Research. 1995 Nov 1
• 14 citations
  Evidence against a direct role for the induction of c-jun expression in the mediation of drug-induced apoptosis in human acute leukemia cells.
  Gloria Bullock, Swapan K. Ray, John C. Reed, Toshiyuki Miyashita, Ana Maria Ibrado, Yue Huang, Kapil N. Bhalla> ;Clinical Cancer Research. 1995 May 1
• 7 citations
  pIXY321 protects against Ara-C or taxol-induced apoptosis and loss of clonogenic survival of normal human bone marrow progenitor cells.
  Kapil N. Bhalla, Ana Maria Ibrado, J. E. Brandt, Swapan K. Ray, Yue Huang, Caroline Tang, A. Nawabi, R. Hoffman> ;Leukemia. 1995 Jan 1
• 48 citations
  1-β-d-arabinofuranosylcytosine-, mitoxantrone-, and paclitaxel-induced apoptosis in HL-60 cells: improved method for detection of internucleosomal DNA fragmentation
  Swapan K. Ray, Vidya Ponnathpur, Yue Huang, Caroline Tang, Mary Ella Mahoney, Ana Maria Ibrado, Gloria Bullock, Kapil N. Bhalla> ;Cancer Chemotherapy and Pharmacology. 1994 Sep 1
• 71 citations
  Characterization of a human myeloid leukemia cell line highly resistant to taxol
  Kapil N. Bhalla, Vue Huang, Caroline Tang, Sally E. Self, Swapan K. Ray, Mary Ella Mahoney, Vidyashankar Ponnathpur, Elena Tourkina, Ana Maria Ibrado, Gloria Bullock, ...> ;Leukemia. 1994 Mar 1
• 3 citations
  Combined antileukemic activity of pIXY 321 and Ara-C against human acute myeloid leukemia cells.
  Caroline Tang, Yue Huang, Vidya Ponnathpur, Swapan K. Ray, Mary Ella Mahoney, Gloria Bullock, Ana Maria Ibrado, Kapil N. Bhalla> ;Leukemia & Lymphoma. 1994 Jan 1
• 25 citations
  Effect of combined treatment with interleukin-3 and interleukin-6 on 4-hydroperoxycyclophosphamide-induced programmed cell death or apoptosis in human myeloid leukemia...
  Gloria Bullock, Caroline Tang, Elena Tourkina, Ana Maria Ibrado, Jose Lutzky, Yue Huang, Mary Ella Mahoney, Kapil N. Bhalla> ;Experimental Hematology. 1993 Dec 1
• 63 citations
  High-dose mitoxantrone induces programmed cell death or apoptosis in human myeloid leukemia cells.
  Kapil N. Bhalla, Ana Maria Ibrado, Elena Tourkina, Caroline Tang, Steven Grant, Gloria Bullock, Yue Huang, Vidya Ponnathpur, Mary Ella Mahoney> ;Blood. 1993 Nov 15
• 12 citations
  Effect of Hemopoietic Growth Factors G-CSF and pIXY 321 on the Activity of High Dose ARA-C in Human Myeloid Leukemia Cells
  Kapil N. Bhalla, Elena Tourkina, Yue Huang, Caroline Tang, Mary Ella Mahoney, Ana Maria Ibrado> ;Leukemia & Lymphoma. 1993 Jan 1
• 251 citations
  Taxol induces internucleosomal DNA fragmentation associated with programmed cell death in human myeloid leukemia cells.
  Kapil N. Bhalla, Ana Maria Ibrado, Elena Tourkina, Caroline Tang, Mary Ella Mahoney, Yue Huang> ;Leukemia. 1993 Apr 1
• 42 citations
  Granulocyte-macrophage colony-stimulating factor/interleukin-3 fusion protein (pIXY 321) enhances high-dose Ara-C-induced programmed cell death or apoptosis in human m...
  Kapil N. Bhalla, Caroline Tang, Ana Maria Ibrado, Steven Grant, Elena Tourkina, Charles Holladay, Monty Hughes, Mary Ella Mahoney, Yue Huang> ;Blood. 1992 Dec 1
• 12 citations
  Deoxycytidine protects normal bone marrow progenitors against Ara-C and gemcitabine cytotoxicity without compromising their activity against cisplatin-resistant human ...
  Kapil N. Bhalla, Charles Holladay, Jose Lutzky, Ana Maria Ibrado, Gloria Bullock, Michelle Jasiok, Shivendra V. Singh> ;Gynecologic Oncology. 1992 Apr 1
• 5 citations
  Effect of combined treatment with interleukin-3 and interleukin-6 on 4-hydroperoxycyclophosphamide-mediated reduction of glutathione levels and cytotoxicity in normal ...
  Kapil N. Bhalla, Gloria Bullock, Jose Lutzky, Charles Holladay, Ana Maria Ibrado, Michelle Jasiok, Shivendra V. Singh> ;Leukemia. 1992 Jan 1
• 52 citations
  Treatment with interleukin-3 plus granulocyte-macrophage colony-stimulating factors improves the selectivity of Ara-C in vitro against acute myeloid leukemia blasts
  Kapil N. Bhalla, Charles Holladay, Z. Arlin, Steven Grant, Ana Maria Ibrado, Michelle Jasiok> ;Blood. 1991 Nov 15
• Join now to see all