AnanthaKrishnanHarijithMD

PubMed

• Sphingosine kinase 1-specific inhibitor PF543 reduces goblet cell metaplasia of bronchial epithelium in an acute asthma model.
  Sudhadevi, T., Ackerman, S., Jafri, A., Basa, P., Ha, A., Natarajan, V., Harijith, A.> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2024 Mar 1
• 6 citations
  The Role of Sphingolipid Signaling in Oxidative Lung Injury and Pathogenesis of Bronchopulmonary Dysplasia.
  Jaya M Thomas, Tara Sudhadevi, Prathima Basa, Alison W Ha, Viswanathan Natarajan, Anantha Harijith> ;International Journal of Molecular Sciences. 2022 Jan 23
• 3 citations
  NOX4 Mediates Epithelial Cell Death in Hyperoxic Acute Lung Injury Through Mitochondrial Reactive Oxygen Species.
  Anantha Harijith, Prathima Basa, Alison Ha, Jaya Thomas, Anjum Jafri, Panfeng Fu, Peter M MacFarlane, Thomas M Raffay, Viswanathan Natarajan, Tara Sudhadevi> ;Frontiers in Pharmacology. 2022 Jan 1
• A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease.
  Tara Sudhadevi, Alison W. Ha, Anantha Harijith> ;Journal of Visualized Experiments. 2021 Aug 4
• 6 citations
  Hyperoxia-induced S1P1 signaling reduced angiogenesis by suppression of TIE-2 leading to experimental bronchopulmonary dysplasia
  Tara Sudhadevi, Anjum Jafri, Alison W. Ha, Prathima Basa, Jaya M Thomas, Panfeng Fu, Kishore K. Wary, Dolly Mehta, Viswanathan Natarajan, Anantha Harijith> ;Cell Biochemistry and Biophysics. 2021 Jun 27
• 7 citations
  Sphingosine kinase 1 regulates lysyl oxidase through STAT3 in hyperoxia-mediated neonatal lung injury.
  Alison W. Ha, Tao Bai, David L. Ebenezer, Tanvi Sethi, Tara Sudhadevi, Lizar A. Mangio, Steven Garzon, Gloria S. Pryhuber, Viswanathan Natarajan, Anantha Harijith> ;Thorax. 2021 Apr 21
• 1 citations
  The twofold NICU challenge: avoiding hypoxia and hyperoxia.
  Richard J. Martin, Anantha Harijith> ;Pediatric Research. 2021 Apr 13
• 11 citations
  NOX4 Mediates Pseudomonas aeruginosa-Induced Nuclear Reactive Oxygen Species Generation and Chromatin Remodeling in Lung Epithelium
  Panfeng Fu, Ramaswamy Ramchandran, Tara Sudhadevi, Prasanth P K Kumar, Yashaswin Krishnan, Yuru Liu, Yutong Zhao, Narasimham L. Parinandi, Anantha Harijith, Junichi Sa...> ;Antioxidants. 2021 Mar 17
• 15 citations
  The Sphingosine Kinase 1 Inhibitor, PF543, Mitigates Pulmonary Fibrosis by Reducing Lung Epithelial Cell mtDNA Damage and Recruitment of Fibrogenic Monocytes.
  Paul Cheresh, Seok Jo Kim, Long Shuang Huang, Satoshi Watanabe, Nikita Joshi, Kinola J.N. Williams, Monica Chi, Ziyan Lu, Anantha Harijith, Anjana V. Yeldandi, Anna P....> ;International Journal of Molecular Sciences. 2020 Aug 5
• 11 citations
  Lysocardiolipin acyltransferase regulates NSCLC cell proliferation and migration by modulating mitochondrial dynamics
  Long Shuang Huang, Sainath R. Kotha, Sreedevi Avasarala, Michelle VanScoyk, Robert A. Winn, Arjun Pennathur, Puttaraju S. Yashaswini, Mounica Bandela, Ravi Salgia, Yul...> ;The Journal of Biological Chemistry. 2020 Jul 30
• 18 citations
  Neonatal therapy with PF543, a sphingosine kinase 1 inhibitor, ameliorates hyperoxia-induced airway remodeling in a murine model of bronchopulmonary dysplasia.
  Alison W. Ha, Tara Sudhadevi, David L. Ebenezer, Panfeng Fu, Evgeny Berdyshev, Steven J. Ackerman, Viswanathan Natarajan, Anantha Harijith> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2020 Sep 1
• 7 citations
  Advancements in understanding the role of lysophospholipids and their receptors in lung disorders including bronchopulmonary dysplasia.
  Tara Sudhadevi, Alison W. Ha, David L. Ebenezer, Panfeng Fu, Vijay Putherickal, Viswanathan Natarajan, Anantha Harijith> ;Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 2020 Jul 1
• 19 citations
  S1P and plasmalogen derived fatty aldehydes in cellular signaling and functions
  David L. Ebenezer, Panfeng Fu, Ramaswamy Ramchandran, Alison W. Ha, Vijay Putherickal, Tara Sudhadevi, Anantha Harijith, Fabian Schumacher, Burkhard Kleuser, Viswanath...> ;Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 2020 Mar 12
• 63 citations
  Sphingosine Kinase 1/S1P Signaling Contributes to Pulmonary Fibrosis by Activating Hippo/YAP Pathway and Mitochondrial Reactive Oxygen Species in Lung Fibroblasts
  Long Shuang Huang, Tara Sudhadevi, Panfeng Fu, Prasanth-Kumar Punathil-Kannan, David L. Ebenezer, Ramaswamy Ramchandran, Vijay Putherickal, Paul Cheresh, Guofei Zhou, ...> ;International Journal of Molecular Sciences. 2020 Mar 17
• 24 citations
  Colony-stimulating factor 1 and its receptor are new potential therapeutic targets for allergic asthma
  Hyung-Geun Moon, Seung Jae Kim, Myoung Kyu Lee, Homan Kang, Hak Soo Choi, Anantha Harijith, Jinhong Ren, Viswanathan Natarajan, John W. Christman, Steven J. Ackerman, ...> ;Allergy. 2020 Feb 1
• 16 citations
  Genetic deletion of Sphk2 confers protection against Pseudomonas aeruginosa mediated differential expression of genes related to virulent infection and inflammation in...
  David L. Ebenezer, Panfeng Fu, Yashaswin Krishnan, Mark Maienschein-Cline, Hong Hu, Segun Jung, Ravi Madduri, Zarema Arbieva, Anantha Harijith, Viswanathan Natarajan> ;BMC Genomics. 2019 Dec 16
• 33 citations
  Pseudomonas aeruginosa stimulates nuclear sphingosine-1-phosphate generation and epigenetic regulation of lung inflammatory injury.
  David L. Ebenezer, Evgeny Berdyshev, Irina Bronova, Yuru Liu, Chinnaswamy Tiruppathi, Yulia Komarova, Elizaveta V. Benevolenskaya, Vidyani Suryadevara, Alison W. Ha, A...> ;Thorax. 2019 Feb 5
• 30 citations
  Nuclear lipid mediators: Role of nuclear sphingolipids and sphingosine-1-phosphate signaling in epigenetic regulation of inflammation and gene expression.
  Panfeng Fu, David L. Ebenezer, Alison W. Ha, Vidyani Suryadevara, Anantha Harijith, Viswanathan Natarajan> ;Journal of Cellular Biochemistry. 2018 Aug 1
• 43 citations
  Novel peptide nanoparticle–biased antagonist of CCR3 blocks eosinophil recruitment and airway hyperresponsiveness
  Milica Grozdanovic, Kimberly G. Laffey, Hazem Abdelkarim, Ben Hitchinson, Anantha Harijith, Hyung Geon Moon, Gye Young Park, Lee K. Rousslang, Joanne C. Masterson, Gle...> ;The Journal of Allergy and Clinical Immunology. 2019 Feb 1
• 13 citations
  Sphingolipids Signaling in Lamellipodia Formation and Enhancement of Endothelial Barrier Function
  Panfeng Fu, Mark Shaaya, Anantha Harijith, Jeffrey R. Jacobson, Andrei V. Karginov, Viswanathan Natarajan> ;Current Topics in Membranes. 2018 Jan 1
• 25 citations
  Sphingolipids in Ventilator Induced Lung Injury: Role of Sphingosine-1-Phosphate Lyase.
  Vidyani Suryadevara, Panfeng Fu, David L. Ebenezer, Evgeny Berdyshev, Irina Bronova, Long Shuang Huang, Anantha Harijith, Viswanathan Natarajan> ;International Journal of Molecular Sciences. 2018 Jan 1
• 22 citations
  The Role of Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Lung Architecture Remodeling
  Anantha Harijith, Viswanathan Natarajan, Panfeng Fu> ;Antioxidants. 2017 Dec 19
• 13 citations
  Expression profiling of genes regulated by sphingosine kinase1 signaling in a murine model of hyperoxia induced neonatal bronchopulmonary dysplasia
  Viswanathan Natarajan, Alison W. Ha, Yangbasai Dong, Narsa M. Reddy, David L. Ebenezer, Prasad Kanteti, Sekhar P. Reddy, J. Usha Raj, Zhengdeng Lei, Mark Maienschein-C...> ;BMC Genomics. 2017 Aug 29
• 27 citations
  Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium
  Panfeng Fu, David L. Ebenezer, Evgeny Berdyshev, Irina Bronova, Mark Shaaya, Anantha Harijith, Viswanathan Natarajan> ;The Journal of Biological Chemistry. 2016 Dec 30
• 27 citations
  Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium
  Anantha Harijith, Srikanth Pendyala, David L. Ebenezer, Alison W. Ha, Panfeng Fu, Yue-Ting Wang, Ke Ma, Peter T. Toth, Evgeny Berdyshev, Prasad Kanteti, Viswanathan Na...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2016 Aug 1
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