AndreaLRichardsonMD

PubMed

• 4 citations
  Standardized Definitions for Efficacy End Points in Neoadjuvant Breast Cancer Clinical Trials: NeoSTEEP.
  Jennifer K Litton, Meredith M Regan, Lajos Pusztai, Hope S Rugo, Sara M Tolaney, Elizabeth Garrett-Mayer, Laleh Amiri-Kordestani, Reva K Basho, Ana F Best, Jean-Franco...> ;Journal of Clinical Oncology. 2023 Sep 20
• 42 citations
  Spatial genomics maps the structure, nature and evolution of cancer clones.
  Artem Lomakin, Jessica Svedlund, Carina Strell, Milana Gataric, Artem Shmatko, Gleb Rukhovich, Jun Sung Park, Young Seok Ju, Stefan Dentro, Vitalii Kleshchevnikov, Vas...> ;Nature. 2022 Nov 1
• 10 citations
  Prognostic Utility of Breast Cancer Index to Stratify Distant Recurrence Risk in Invasive Lobular Carcinoma
  Raquel Nunes, Tal Sella, Kai Treuner, Jennifer M. Atkinson, Jenna Wong, Yi Zhang, Pedro Exman, David J. Dabbs, Andrea L. Richardson, Catherine A. Schnabel, Dennis C. S...> ;Clinical Cancer Research. 2021 Oct 15
• 55 citations
  Homologous recombination deficiency (HRD) score in germline BRCA2- versus ATM-altered prostate cancer.
  Tamara L. Lotan, Daniela C. Salles, Sanjana Murali, Edward M. Schaeffer, Jerry S. Lanchbury, William B. Isaacs, Robert S. Brown, Andrea L. Richardson, Olivier Cussenot...> ;Modern Pathology. 2021 Jan 18
• 41 citations
  TBCRC 030: a phase II study of preoperative cisplatin versus paclitaxel in triple-negative breast cancer: evaluating the homologous recombination deficiency (HRD) biom...
  Erica L. Mayer, Vandana G. Abramson, Rachel C. Jankowitz, Carla I. Falkson, Paul K. Marcom, Tiffany A. Traina, Lisa A. Carey, Mothaffar F. Rimawi, Jennifer M. Specht, ...> ;Annals of Oncology. 2020 Nov 1
• 18 citations
  Association of Tumor-Infiltrating Lymphocytes with Homologous Recombination Deficiency and BRCA1/2 Status in Patients with Early Triple-Negative Breast Cancer: A Poole...
  Melinda L. Telli, Charles Chu, Sunil Badve, Shaveta Vinayak, Daniel P. Silver, Steven J. Isakoff, Virginia G. Kaklamani, William J. Gradishar, Vered Stearns, Roisin M....> ;Clinical Cancer Research. 2020 Jun 1
• 100 citations
  Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages
  Jennifer M. Rosenbluth, Ron C. J. Schackmann, G. Kenneth Gray, Laura M. Selfors, Carman Man-Chung Li, Mackenzie Boedicker, Hendrik J. Kuiken, Andrea L. Richardson, Jan...> ;Nature Communications. 2020 Apr 6
• 70 citations
  Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents
  Ádám Póti, Hella Gyergyák, Eszter Németh, Orsolya Rusz, Szilárd Tóth, Csenger Kovácsházi, Dan Chen, Bernadett Szikriszt, Sándor Spisák, Shunichi Takeda, Gergely Szakác...> ;Genome Biology. 2019 Nov 14
• 34 citations
  Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ.
  Lina Ding, Ying Su, Anne Fassl, Kunihiko Hinohara, Xintao Qiu, Nicholas W. Harper, Sung Jin Huh, Noga Bloushtain-Qimron, Bojana Jovanovic, Muhammad B. Ekram, Xiaoyuan ...> ;Nature Communications. 2019 Sep 13
• 33 citations
  Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation
  Arie B. Brinkman, Serena Nik-Zainal, Femke Simmer, F. Germán Rodríguez-González, Marcel Smid, Ludmil B. Alexandrov, Adam Butler, Sancha Martin, Helen Davies, Dominik G...> ;Nature Communications. 2019 Apr 15
• 76 citations
  The circular RNome of primary breast cancer
  Marcel Smid, Saskia M. Wilting, Katharina Uhr, F. Germán Rodríguez-González, Vanja de Weerd, Wendy J. C. Prager-van der Smissen, Michelle van der Vlugt-Daane, Anne van...> ;Genome Research. 2019 Mar 1
• 11 citations
  Exploring Biomarkers of Phosphoinositide 3-Kinase Pathway Activation in the Treatment of Hormone Receptor Positive, Human Epidermal Growth Receptor 2 Negative Advanced...
  Virginia G. Kaklamani, Andrea L. Richardson, Carlos L. Arteaga> ;The Oncologist. 2019 Mar 1
• 9 citations
  Interpretation of Optical Coherence Tomography Images for Breast Tissue Assessment
  Kiran S. Yemul, Adam M. Zysk, Andrea L. Richardson, Krishnarao V. Tangella, Lisa K. Jacobs> ;Surgical Innovation. 2019 Feb 1
• 9 citations
  Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences.
  Serena Nik-Zainal, Helen Davies, Johan Staaf, Manasa Ramakrishna, Dominik Glodzik, Xueqing Zou, Inigo Martincorena, Ludmil B. Alexandrov, Sancha Martin, David C. Wedge...> ;Nature. 2019 Feb 7
• 39 citations
  Overexpression of BLM promotes DNA damage and increased sensitivity to platinum salts in triple negative breast and serous ovarian cancers
  Nicolai Juul Birkbak, Yi Li, Shailja Pathania, April Greene-Colozzi, Matija Dreze, Christian Bowman-Colin, Zsofia Sztupinszki, Marcin Krzystanek, Miklos Diossy, Nadine...> ;Annals of Oncology. 2018 Apr 1
• 40 citations
  Protein acyltransferase DHHC3 regulates breast tumor growth, oxidative stress, and senescence
  Chandan Sharma, Hong-Xing Wang, Qinglin Li, Konstantin Knoblich, Emily S. Reisenbichler, Andrea L. Richardson, Martin E. Hemler> ;Cancer Research. 2017 Dec 15
• 1 citations
  Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers.
  Dominik Glodzik, Sandro Morganella, Helen Davies, Peter T Simpson, Yilong Li, Xueqing Zou, Javier Diez-Perez, Johan Staaf, Ludmil B Alexandrov, Marcel Smid, Arie B Bri...> ;Nature Genetics. 2017 Oct 27
• 219 citations
  Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.
  Roger L. Milne, Karoline Kuchenbaecker, Kyriaki Michailidou, Jonathan Beesley, Siddhartha Kar, Sara Lindström, Shirley Hui, Audrey Lemaçon, Penny Soucy, Joe Dennis, Xi...> ;Nature Genetics. 2017 Oct 23
• 146 citations
  Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition.
  Carlos R. Gil Del Alcazar, Sung Jin Huh, Muhammad B. Ekram, Anne Trinh, Lin Liu, Francisco Beca, Xiaoyuan Zi, Minsuk Kwak, Helga Bergholtz, Ying Su, Lina Ding, Hege G....> ;Cancer Discovery. 2017 Oct 1
• 64 citations
  Whole-Genome Sequencing Reveals Breast Cancers with Mismatch Repair Deficiency.
  Helen Davies, Sandro Morganella, Colin A. Purdie, Se Jin Jang, Elin Borgen, Hege G. Russnes, Dominik Glodzik, Xueqing Zou, Alain Viari, Andrea L. Richardson, Anne Lise...> ;Cancer Research. 2017 Sep 15
• 15 citations
  Identifying DNase I hypersensitive sites as driver distal regulatory elements in breast cancer.
  Matteo Dâ²Antonio, Donate Weghorn, Agnieszka Dâ²Antonio-Chronowska, Florence Coulet, Katrina M. Olson, Christopher DeBoever, Frauke Drees, Angelo Arias, Hakan Alakus, ...> ;Nature Communications. 2017 Sep 5
• 35 citations
  Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions.
  J Zámborszky, B Szikriszt, J Z Gervai, O Pipek, Á Póti, M Krzystanek, D Ribli, J M Szalai-Gindl, I Csabai, Z Szallasi, C Swanton, A L Richardson, D Szüts> ;Oncogene. 2017 Aug 31
• 407 citations
  Genomic Evolution of Breast Cancer Metastasis and Relapse
  Lucy R. Yates, Stian Knappskog, David C. Wedge, James H.R. Farmery, Santiago Gonzalez, Inigo Martincorena, Ludmil B. Alexandrov, Peter Van Loo, Hans Kristian Haugland,...> ;Cancer Cell. 2017 Aug 14
• 214 citations
  Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
  Catherine M. Phelan, Karoline Kuchenbaecker, Jonathan Tyrer, Siddhartha Kar, Kate Lawrenson, Stacey J. Winham, Joe Dennis, Ailith Pirie, Marjorie J. Riggan, Ganna Chor...> ;Nature Genetics. 2017 May 1
• 611 citations
  HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures
  Helen Davies, Dominik Glodzik, Sandro Morganella, Lucy R. Yates, Johan Staaf, Xueqing Zou, Manasa Ramakrishna, Sancha Martin, Sandrine Boyault, Anieta M. Sieuwerts, Pe...> ;Nature Medicine. 2017 Apr 1
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