AndrejSpecMD, MSCI

PubMed

• Incidence and Mortality of COVID-19-Associated Invasive Fungal Infections Among Critically Ill Intubated Patients: A Multicenter Retrospective Cohort Analysis.
  Julio C Zuniga-Moya, Benjamin Papadopoulos, Armaghan-E-Rehman Mansoor, Patrick B Mazi, Adriana M Rauseo, Andrej Spec> ;Open Forum Infectious Diseases. 2024 Apr 1
• MSG-15: Super-Bioavailability Itraconazole Versus Conventional Itraconazole in the Treatment of Endemic Mycoses-A Multicenter, Open-Label, Randomized Comparative Trial.
  Andrej Spec, George R Thompson, Marisa H Miceli, Justin Hayes, Laurie Proia, David McKinsey, Ana Belen Arauz, Kathleen Mullane, Gerald McGwin, Rachel McMullen, Tyler P...> ;Open Forum Infectious Diseases. 2024 Mar 1
• 1 citations
  Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM.
  Christina C Chang, Thomas S Harrison, Tihana A Bicanic, Methee Chayakulkeeree, Tania C Sorrell, Adilia Warris, Ferry Hagen, Andrej Spec, Rita Oladele, Nelesh P Govende...> ;The Lancet. Infectious Diseases. 2024 Feb 9
• 4 citations
  Description of Cryptococcosis Following SARS-CoV-2 Infection: A Disease Survey Through the Mycosis Study Group Education and Research Consortium (MSG-19).
  Jeremey Walker, Todd McCarty, Gerald McGwin, Eloy E Ordaya, Paschalis Vergidis, Luis Ostrosky-Zeichner, Mehriban Mammadova, Andrej Spec, Adriana M Rauseo, Gabriel Vilc...> ;Clinical Infectious Diseases. 2024 Feb 17
• Reply to Collis et al.
  Adriana M Rauseo, Andrej Spec> ;Open Forum Infectious Diseases. 2023 Jul 1
• 6 citations
  Single High Dose of Liposomal Amphotericin B in Human Immunodeficiency Virus/AIDS-Related Disseminated Histoplasmosis: A Randomized Trial.
  Alessandro C Pasqualotto, Daiane Dalla Lana, Cassia S M Godoy, Terezinha do Menino Jesus Silva Leitão, Monica B Bay, Lisandra Serra Damasceno, Renata B A Soares, Roger...> ;Clinical Infectious Diseases. 2023 Oct 13
• 5 citations
  Corticosteroids Increase the Risk of Invasive Fungal Infections More Than Tumor Necrosis Factor-Alpha Inhibitors in Patients With Inflammatory Bowel Disease.
  Martin H Gregory, Andrej Spec, Dustin Stwalley, Anas Gremida, Carlos Mejia-Chew, Katelin B Nickel, Matthew A Ciorba, Richard P Rood, Margaret A Olsen, Parakkal Deepak> ;Crohn's & Colitis 360. 2023 Apr 1
• 2 citations
  Prevalence of Ocular Complications in Candidemia: Defining the "Battlefield".
  Adriana M Rauseo, Andrej Spec> ;Clinical Infectious Diseases. 2023 May 24
• 28 citations
  The Geographic Distribution of Dimorphic Mycoses in the United States for the Modern Era.
  Patrick B Mazi, John M Sahrmann, Margaret A Olsen, Ariella Coler-Reilly, Adriana M Rauseo, Matthew Pullen, Julio C Zuniga-Moya, William G Powderly, Andrej Spec> ;Clinical Infectious Diseases. 2023 Apr 3
• 4 citations
  Creation and Internal Validation of a Clinical Predictive Model for Fluconazole Resistance in Patients WithBloodstream Infection.
  Adriana M Rauseo, Margaret A Olsen, Dustin Stwalley, Patrick B Mazi, Lindsey Larson, William G Powderly, Andrej Spec> ;Open Forum Infectious Diseases. 2022 Sep 1
• 1 citations
  Metabolic syndrome in people with HIV from Guatemala: analysis of components and risk factors.
  Dean W Ortíz, Hugo E Marroquin, Lindsey Larson, Katherine B Franco, Andrej Spec, Johanna R Melendez, Rodolfo Pinzón, Ana J Samayoa, Carlos Mejia-Chew, Jane A O Halloran> ;International Journal of STD & AIDS. 2022 Oct 1
• 2 citations
  Management of Histoplasmosis by Infectious Disease Physicians.
  Patrick B Mazi, Sandra R Arnold, John W Baddley, Nathan C Bahr, Susan E Beekmann, Todd P McCarty, Philip M Polgreen, Adriana M Rauseo, Andrej Spec> ;Open Forum Infectious Diseases. 2022 Jul 1
• 21 citations
  Noninvasive Testing and Surrogate Markers in Invasive Fungal Diseases.
  George R Thompson 3rd, David R Boulware, Nathan C Bahr, Cornelius J Clancy, Thomas S Harrison, Carol A Kauffman, Thuy Le, Marisa H Miceli, Eleftherios Mylonakis, M Hon...> ;Open Forum Infectious Diseases. 2022 Jun 1
• 1 citations
  Digital Strategy and Social Media for Infectious Diseases.
  Jasmine R Marcelin, Carlos Del Rio, Andrej Spec, Talia H Swartz> ;Clinical Infectious Diseases. 2022 May 15
• 5 citations
  Systemic antifungal therapy with isavuconazonium sulfate or other agents in adults with invasive mucormycosis or invasive aspergillosis (non-fumigatus): A multicentre,...
  George R Thompson 3rd, Julia Garcia-Diaz, Marisa H Miceli, M Hong Nguyen, Luis Ostrosky-Zeichner, Jo-Anne H Young, Cynthia E Fisher, Nina M Clark, Richard N Greenberg,...> ;Mycoses. 2022 Feb 1
• Reply to Ito and Ogawa.
  Patrick Mazi, Andrej Spec> ;Clinical Infectious Diseases. 2022 Aug 31
• 13 citations
  Attributable Mortality of Candida Bloodstream Infections in the Modern Era: A Propensity Score Analysis.
  Patrick B Mazi, Margaret A Olsen, Dustin Stwalley, Adriana M Rauseo, Chapelle Ayres, William G Powderly, Andrej Spec> ;Clinical Infectious Diseases. 2022 Sep 29
• 1 citations
  Disseminated Infection Due toin a Patient with Acute Myelogenous Leukemia.
  Ra'ed Jabr, Rachael M Liesman, Venkata Rakesh Sethapati, D Matthew Shoemaker, Andrej Spec, Wissam El Atrouni> ;Kansas Journal of Medicine. 2022 Jan 1
• 62 citations
  COVID-19-associated Invasive Fungal Infection
  John W Baddley, George Richard Thompson, Sharon C.-A. Chen, P. Lewis White, Melissa D. Johnson, M. Hong Nguyen, Ilan S. Schwartz, Andrej Spec, Luis Ostrosky-Zeichner, ...> ;Open Forum Infectious Diseases. 2021 Nov 16
• 3 citations
  Risk factors for mortality and multidrug resistance in pulmonary tuberculosis in Guatemala: A retrospective analysis of mandatory reporting.
  Kevin Montes, Himachandana Atluri, Hibeb Silvestre Tuch, Lucrecia Ramirez, Juan Paiz, Ana Hesse Lopez, Thomas C. Bailey, Andrej Spec, Carlos Mejia-Chew> ;Journal of Clinical Tuberculosis and Other Mycobacterial Diseases. 2021 Nov 15
• 1 citations
  Clinical predictive models of invasive Candida infection: A systematic literature review.
  Adriana M Rauseo, Abdullah Aljorayid, Margaret A. Olsen, Lindsey Larson, Kim Lipsey, William G. Powderly, Andrej Spec> ;Medical Mycology. 2021 Nov 3
• 4 citations
  Factors associated with viremia in people living with HIV on antiretroviral therapy in Guatemala
  Dean W. Ortíz, Olivia Roberts-Sano, Hugo E. Marroquin, Lindsey Larson, Katherine B. Franco, Andrej Spec, Johanna Meléndez, Rodolfo Pinzon, Ana J. Samayoa, Carlos Mejia...> ;AIDS Research and Therapy. 2021 Oct 27
• 147 citations
  The Antifungal Pipeline: Fosmanogepix, Ibrexafungerp, Olorofim, Opelconazole, and Rezafungin.
  Martin Hoenigl, Rosanne Sprute, Matthias Egger, Amir Arastehfar, Oliver A. Cornely, Robert Krause, Cornelia Lass-Flörl, Juergen Prattes, Andrej Spec, George Richard Th...> ;Drugs. 2021 Oct 9
• 10 citations
  Harnessing the Potential of Multiomics Studies for Precision Medicine in Infectious Disease.
  Rebecca A Ward, Nima Aghaeepour, Roby P. Bhattacharyya, Clary B. Clish, Brice Gaudilliere, Nir Hacohen, Michael K. Mansour, Philip A. Mudd, Shravani Pasupneti, Rachel ...> ;Open Forum Infectious Diseases. 2021 Sep 25
• 73 citations
  Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM
  Sharon C.-A. Chen, John R. Perfect, Arnaldo Lopes Colombo, Oliver A. Cornely, Andreas H. Groll, Danila Seidel, Kerstin Albus, Joao N de Almedia, Guillermo Garcia-Effro...> ;The Lancet. Infectious Diseases. 2021 Aug 19
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Journal Articles

• AST to ALT Ratio is Elevated in Disseminated Histoplasmosis as Compared to Localized Pulmonary Disease and Other Endemic Mycoses  
  Spec A, Barrios CR, Ahmad U, Proia LA, Medical Mycology, 1/1/2016
• Community-associated methicillin-resistant Staphylococcus aureus colonization burden in HIV-infected patients  
  Popovich KJ, Hota B, Aroutcheva A, Kurien L, Patel J, Lyles-Banks R, Grasso AE, Spec A, Beavis KG, Hayden MK, Weinstein RA, Clinical Infectious Disease, 1/1/2013

Books/Book Chapters

• The Washington Manuel Infectious Disease Subspecialty Consult. 
  Chapter: Dimorphic Fungal Infections 
  Raval K, Spec AEditors: Liang S, Kirmani N.Lippincott Williams and Wilkins2018

Abstracts/Posters

• Risk factors and mortality associated with fluconazole resistant candida bloodstream infections.
  Spec A, Hsueh K, Kronen R, Lin C, Powderly W, 8th Trends in Medical Mycology, Belgrade, Serbia, 1/1/2017
• Retrospective analysis of cryptococcal Presentation and Outcomes in HIV, Transplant and Non-HIV/Non-Transplant cohort
  Raval K, Powderly W, Spec A, Infectious Disease Society of America, San Diego, CA, 1/1/2017
• Risk factors predicting Candida glabrata fungemia.
  O’Halloran J, Hsueh K, Kronen R, Lin C, Powderly W, Spec A., Infectious Disease Society of America, San Diego, CA, 1/1/2017
• Risk Predictive Model for 90-Day Mortality in Candida Bloodstream Infection
  Lin C, Hsueh K, Kronen R, Powderly W, Spec A, Infectious Disease Society of America, San Diego, CA, 1/1/2017
• Creation and Assessment of a Clinical Predictive Calculator and Mortality Associated with Candida krusei Bloodstream Infections.
  Kronen R, Hsueh K, Lin C, Powderly W, Spec A., Infectious Disease Society of America, San Diego, CA, 1/1/2017
• Infectious Disease Consult Is a Strong Predictor of Reduced Mortality in Cryptococcosis
  Spec A, Raval, K, Powderly, W, Infectious Disease Society of America, New Orleans, LA, 1/1/2016
• AIDS-defining Illnesses at Initial Diagnosis of HIV in a Large Guatemalan Cohort
  Reinhardt S, Spec A, Melendez J, Alonzo A, Ross I, Powderly WG, Mejia C, fectious Disease Society of America, New Orleans, LA, 1/1/2016
• Early HIV diagnosis in Guatemala; an elusive opportunity
  Melendez J, Spec A, Alonzo A, Powderly WG, Mejia C, Infectious Disease Society of America, New Orleans, LA, 1/1/2016
• Infectious Disease Consult Is a Strong Predictor of Reduced Mortality in Cryptococcosis.
  Spec A, Raval, K, Powderly, W, Infectious Disease Society of America, New Orleans, LA, 1/1/2016
• AIDS-defining Illnesses at Initial Diagnosis of HIV in a Large Guatemalan Cohort.
  Reinhardt S, Spec A, Melendez J, Alonzo A, Ross I, Powderly WG, Mejia C., Infectious Disease Society of America, New Orleans, LA, 1/1/2016
• Early HIV diagnosis in Guatemala; an elusive opportunity.
  Meléndez J, Spec A, Alonzo A, Powderly WG, Mejia C, Infectious Disease Society of America, New Orleans, LA, 1/1/2016
• The Changing Epidemiology of Cryptococcal Disease – a Retrospective Population-Based Study
  George, I., Spec A., Powderly, WG., Santos, C, Infectious Disease Society of America, San Diego, CA, 1/1/2015
• Predicting Candida Species with Decreased Fluconazole Susceptibility in Candida Blood Stream Infections
  Spec A., Hsueh, K, Powderly, WG, Infectious Disease Society of America, San Diego, CA, 1/1/2015
• T-Cell Exhaustion in Candida Blood Stream Infections
  Spec A., Shindo, Y.,Chang, K., Vazquez-Guillamet, C., Beiter, E., Green, J., Powderly, W., Hotchkiss, R, Infectious Disease Society of America, Philadephia, PA, 1/1/2014
• T-Cell Exhaustion in Candida Blood Stream Infections.
  Spec A., Shindo, Y.,Chang, K., Vazquez-Guillamet, C., Beiter, E., Green, J., Powderly, W., Hotchkiss, R., Infectious Disease Society of America, Philadephia, PA, 1/1/2014
• Community-Associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA) Extra-Nasal Colonization in HIV-Infected Patient
  Popovich, K., Hota, B., Kurien, L., Patel, J., Lyles, R, Aroutcheva, A., Grasso, A., Spec A, Lough, J., Beavis, K., Hayden, M., Weinstein, R, Conference on Retroviruses and Opportunistic Infections, Seattle, WA, 1/1/2012
• Community-Associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA) Extra-Nasal Colonization in HIV-Infected Patient.
  Popovich, K., Hota, B., Kurien, L., Patel, J., Lyles, R, Aroutcheva, A., Grasso, A., Spec A, Lough, J., Beavis, K., Hayden, M., Weinstein, R, Conference on Retroviruses and Opportunistic Infections, Seattle, WA, 1/1/2012
• Thoracic Actinomycosis with Chylothorax in a Diabetic Patient with Poor Dentition
  Srivastava, P., Spec A, Caskey, R, Mizock, B., American College of Physicians (ACP) Regional Meeting, Chicago, IL, 1/1/2010
• Eph/Ephrin Expression in the Developing Gustatory System
  Spec A, Huang R., Rochlin MW, Association for Chemoreception Sciences, Sarasota, FL, 1/1/2005
• Eph/Ephrin Expression in the Developing Gustatory System
  Spec A, Huang R., Rochlin MW, Association for Chemoreception Sciences (AChemS), Sarasota, FL, 1/1/2005
• Differences in Trophic Factor Receptor and EPH Expression May Contribute to Geniculate Nerve Divergence
  Spec A, Kashyap M., Yamout A., Rochlin MW, Association for Chemoreception Sciences, Sarasota, FL, 1/1/2004
• Differences in Trophic Factor Receptor and EPH Expression May Contribute to Geniculate Nerve Divergence.
  Spec A, Kashyap M., Yamout A., Rochlin MW., Association for Chemoreception Sciences (AChemS), Sarasota, FL, 1/1/2004
• Differential Response to Neurotrophic Factors and Neuropilins May Contribute to Sensory Nerve Divergence
  Yamout A, Kashyap M, Spec A, Rochlin MW, Society for Neuroscience, Washington, DC, 1/1/2003
• Differential Response to Neurotrophic Factors and Neuropilins May Contribute to Sensory Nerve Divergence.
  Yamout A, Kashyap M, Spec A, Rochlin MW, Society for Neuroscience, Washington, DC, 1/1/2003
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Lectures

• The Three Guianas, Time Capsules for Understanding the Role of Development in Global Health 
  Rush University Medical Center, Chicago, IL - 1/1/2018
• New Updates and New Horizons in Medical Mycology 
  Washington University of School of Medicine, St Louis, MO - 1/1/2018
• Creation and Assessment of a Clinical Predictive Calculator and Mortality Associated with Candida krusei Bloodstream Infections. 
  San Diego, CA - 1/1/2017
• Cryptococcus Infection Network in non-HIV Cohort (CINCH) study: Initial Report of Treatment and Outcomes 
  New Orleans, LA - 1/1/2016
• Cryptococcus Infection Network in non-HIV Cohort (CINCH) study: Initial Report of Treatment and Outcomes. 
  New Orleans, LA - 1/1/2016
• The Public Health Crisis of Histoplasmosis in Latin America 
  Indianapolis, IN - 1/1/2015
• Diffuse Bilateral Upper Extremity Ulceronecrotic Plaques Due to Alternaria 
  San Francisco, CA - 1/1/2015
• End Stage Liver Disease is a Strong Predictor of Mortality in Cryptococcosis 
  Melbourne, Australia - 1/1/2015
• Building Clinical Care Capacity for Histoplasmosis Through Randomized Controlled Trials 
  Paramaribo, Suriname - 1/1/2015
• End Stage Liver Disease is a Strong Predictor of Mortality in Cryptococcosis. 
  Melbourne, Australia - 1/1/2015
• Paecillomyces spp. Pulmonary Infection in a Bone Marrow Transplant Patient 
  St Louis, MO - 1/1/2014
• Elevation of AST to ALT Ratio in Disseminated Histoplasmosis as Compared to Localized Disease and Other Endemic Fungi 
  San Francisco, CA - 1/1/2013
• Elevation of AST to ALT Ratio in Disseminated Histoplasmosis as Compared to Localized Disease and Other Endemic Fungi. 
  San Francisco, CA - 1/1/2013
• Building Clinical Care Capacity for Histoplasmosis Through Randomized Controlled Trials, Paramaribo, Suriname 
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