AndrewPaulSomlyoJr.MD

Nephrology • Seattle, WA

Physician

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Office
1145 Broadway
Seattle, WA 98122
Phone+1 206-329-1760
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Education & Training

Kaiser Permanente Southern California (Los Angeles)Fellowship, Nephrology, 2006 - 2008
Case Western Reserve University/University Hospitals Cleveland Medical CenterResidency, Internal Medicine, 1997 - 2000
Case Western Reserve University School of MedicineClass of 1997

Certifications & Licensure

CA State Medical License 2000 - Present
WA State Medical License 2008 - 2025
OH State Medical License 2000 - 2000
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Nephrology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011-2012

Publications & Presentations

PubMed

2 citations
Automated electron tomography with scanning transmission electron microscopy.
Jianglin Feng, Andrew P. Somlyo, Avril V. Somlyo, Zhifeng Shao> ;Journal of Microscopy. 2007 Dec 1
Crossbridge cycle in smooth muscle: kinetics assessed with flash photolysis and fluorescent probes
Avril V. Somlyo, Alexander S. Khromov, Martin R. Webb, John E. T. Corrie, Michael A. Ferenczi, David R. Trentham, Andrew P. Somlyo> ;Journal of Muscle Research and Cell Motility. 2004 Jan 1
44 citations
Signal transduction through the RhoA/Rho-kinase pathway in smooth muscle.
Andrew P. Somlyo, Avril V. Somlyo> ;Journal of Muscle Research and Cell Motility. 2004 Jan 1
41 citations
Smooth muscle myosin: regulation and properties.
Avril V. Somlyo, Alexander S. Khromov, Martin R. Webb, Michael A. Ferenczi, David R. Trentham, Zhen-He He, Sitong Sheng, Zhifeng Shao, Andrew P. Somlyo> ;Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 2004 Dec 29
21 citations
Uncoupling of GPCR and RhoA-induced Ca2+-sensitization of chicken amnion smooth muscle lacking CPI-17.
Andra S. Stevenson, John D. Matthew, Masumi Eto, Shizhen Luo, Andrew P. Somlyo, Avril V. Somlyo> ;FEBS Letters. 2004 Dec 3
69 citations
The Crystal Structure of RhoA in Complex with the DH/PH Fragment of PDZRhoGEF, an Activator of the Ca2+ Sensitization Pathway in Smooth Muscle
Urszula Derewenda, Arkadiusz Oleksy, Andra S. Stevenson, Justyna Korczynska, Zbigniew Dauter, Andrew P. Somlyo, Jacek Otlewski, Avril V. Somlyo, Zygmunt S. Derewenda> ;Structure. 2004 Nov 1
12 citations
Myosin Regulatory Light Chain Phosphorylation and Strain Modulate Adenosine Diphosphate Release from Smooth Muscle Myosin
Alexander S. Khromov, Martin R. Webb, Michael A. Ferenczi, David R. Trentham, Andrew P. Somlyo, Avril V. Somlyo> ;Biophysical Journal. 2004 Apr 1
31 citations
Modulation of Ca2+ sensitivity by cyclic nucleotides in smooth muscle from protein kinase G-deficient mice.
Johan Bonnevier, Reinhard Fässler, Andrew P. Somlyo, Avril V. Somlyo, Anders Arner> ;The Journal of Biological Chemistry. 2004 Feb 13
31 citations
Telokin mediates Ca2+-desensitization through activation of myosin phosphatase in phasic and tonic smooth muscle.
Nandini Choudhury, Alexander S. Khromov, Andrew P. Somlyo, Avril V. Somlyo> ;Journal of Muscle Research and Cell Motility. 2004 Jan 1
20 citations
Cryo-atomic force microscopy of unphosphorylated and thiophosphorylated single smooth muscle myosin molecules.
Sitong Sheng, Yan Gao, Alexander S. Khromov, Avril V. Somlyo, Andrew P. Somlyo, Zhifeng Shao> ;The Journal of Biological Chemistry. 2003 Oct 10
1593 citations
Ca2+ Sensitivity of Smooth Muscle and Nonmuscle Myosin II: Modulated by G Proteins, Kinases, and Myosin Phosphatase
Andrew P. Somlyo, Avril V. Somlyo> ;Physiological Reviews. 2003 Oct 1
Structure of a constitutively activated RhoA mutant (Q63L) at 1.55 A resolution.
Longenecker, K., Read, P., Lin, S., Somlyo, A. P., Nakamoto, R. K., Derewenda, Z. S.> ;Acta crystallographica. Section D, Biological crystallography. 2003 Jun 5
36 citations
LPP, a LIM protein highly expressed in smooth muscle
Isabelle Gorenne, Robert K. Nakamoto, Clayton P. Phelps, Mary C. Beckerle, Avril V. Somlyo, Andrew P. Somlyo> ;American Journal of Physiology. Cell Physiology. 2003 May 21
30 citations
Intracellular Chloride Accumulation and Subcellular Elemental Distribution During Atrial Fibrillation
Joseph G. Akar, Thomas H. Everett, Ruoya Ho, Joseph Craft, David E. Haines, Andrew P. Somlyo, Avril V. Somlyo> ;Circulation. 2003 Apr 8
5 citations
Calcium content of peripheral and central mitochondria in the guinea pig myocardium: electron probe analysis
Ruoya Ho, Dongsheng Fan, Avril V. Somlyo, Andrew P. Somlyo> ;Cell Calcium. 2003 Apr 1
78 citations
Rho kinase and matrix metalloproteinase inhibitors cooperate to inhibit angiogenesis and growth of human prostate cancer xenotransplants
Avril V. Somlyo, Clayton P. Phelps, Charles G. diPierro, Masumi Eto, Paul W. Read, Matthew Barrett, Jennifer J. Gibson, M. Christine Burnitz, Charles E. Myers, Andrew ...> ;FASEB Journal. 2003 Feb 1
122 citations
RhoA-mediated Ca2+ Sensitization in Erectile Function
Hua Wang, Masumi Eto, Williams D. Steers, Andrew P. Somlyo, Avril V. Somlyo> ;The Journal of Biological Chemistry. 2002 Aug 23
81 citations
Cooperativity between the Ras-ERK and Rho-Rho kinase pathways in urokinase-type plasminogen activator-stimulated cell migration.
Minji Jo, Keena S. Thomas, Avril V. Somlyo, Andrew P. Somlyo, Steven L. Gonias> ;The Journal of Biological Chemistry. 2002 Apr 5
11 citations
The Sarcoplasmic Reticulum: Then and Now
Andrew P. Somlyo, Avril V. Somlyo> ;Novartis Foundation Symposium. 2002 Jan 1
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Grant Support

Three Dimensional Distribution Of Ion Transporting Membrane Channels/OrganellesNational Heart, Lung, And Blood Institute1995
Three Dimensional Distribution Of Ion Transporting Membrane Channel And OrganelleNational Heart, Lung, And Blood Institute1992–1994
Regulation Of Calcium Ion And ContractionNational Heart, Lung, And Blood Institute1990–1992

Hospital Affiliations

Seattle VA Medical CenterSeattle, Washington
Swedish Cherry Hill CampusSeattle, Washington
UW Medicine/Northwest Hospital & Medical CenterSeattle, Washington
MultiCare Tacoma General HospitalTacoma, Washington
Swedish First Hill CampusSeattle, Washington
Swedish IssaquahIssaquah, Washington

AndrewPaulSomlyoJr.MD

Dr. Somlyo is on Doximity

Education & Training

Certifications & Licensure

Awards, Honors, & Recognition

Publications & Presentations

Grant Support

Hospital Affiliations

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