AndrewMichaelSternMDPhD

PubMed

• 1 citations
  Soluble oligomers or insoluble fibrils? Scientific commentary on "Tau seeding and spreading in vivo is supported by both AD-derived fibrillar and oligomeric tau".
  Andrew M Stern, Dennis J Selkoe> ;Acta Neuropathologica. 2023 Dec 1
• Plasma NT1-tau and Aβcorrelate with age and cognitive function in two large Down syndrome cohorts.
  Andrew M Stern, Kathryn L Van Pelt, Lei Liu, Amirah K Anderson, Beth Ostaszewski, Mark Mapstone, Sid O'Bryant, Melissa E Petersen, Bradley T Christian, Benjamin L Hand...> ;Alzheimer's & Dementia. 2023 Dec 1
• Anti-dementia bias and Medicare regulation of Alzheimer's disease care.
  Andrew M Stern> ;Alzheimer's & Dementia. 2023 Aug 1
• 18 citations
  Abundant Aβ fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer's disease brains.
  Andrew M Stern, Yang Yang, Shanxue Jin, Keitaro Yamashita, Angela L Meunier, Wen Liu, Yuqi Cai, Maria Ericsson, Lei Liu, Michel Goedert, Sjors H W Scheres, Dennis J Se...> ;Neuron. 2023 Jul 5
• 5 citations
  Unfairness to Patients With Alzheimer Disease in Medicare's Coverage of Antiamyloid Immunotherapy.
  Andrew M Stern, Dennis J Selkoe> ;JAMA Neurology. 2022 Oct 1
• 11 citations
  Bioactive human Alzheimer brain soluble Aβ: pathophysiology and therapeutic opportunities.
  Shaomin Li, Andrew M Stern> ;Molecular Psychiatry. 2022 Aug 1
• 6 citations
  A calcium-sensitive antibody isolates soluble amyloid-β aggregates and fibrils from Alzheimer's disease brain.
  Andrew M Stern, Lei Liu, Shanxue Jin, Wen Liu, Angela L Meunier, Maria Ericsson, Michael B Miller, Megan Batson, Tingwan Sun, Sagar Kathuria, David Reczek, Laurent Pra...> ;Brain. 2022 Jul 29
• 1 citations
  Case Study 1: A 55-Year-Old Woman With Progressive Cognitive, Perceptual, and Motor Impairments
  Scott M. McGinnis, Andrew M Stern, Jared K Woods, Matthew Torre, Mel B. Feany, Michael B Miller, David Silbersweig, Seth A. Gale, Kirk R. Daffner> ;The Journal of Neuropsychiatry and Clinical Neurosciences. 2021 Nov 12
• 3 citations
  In situ functional cell phenotyping reveals microdomain networks in colorectal cancer recurrence
  Samantha A. Furman, Andrew M. Stern, Shikhar Uttam, D. Lansing Taylor, Filippo Pullara, Chakra Chennubhotla> ;Cell Reports Methods. 2021 Sep 27
• 17 citations
  An ultra-sensitive immunoassay detects and quantifies soluble Aβ oligomers in human plasma.
  Lei Liu, Hyunchang Kwak, Trebor L. Lawton, Shan-Xue Jin, Angela L. Meunier, Yifan Dang, Beth L. Ostaszewski, Alison C. Pietras, Andrew M. Stern, Dennis J. Selkoe> ;Alzheimer's & Dementia. 2021 Sep 22
• 16 citations
  A systems-level study reveals host-targeted repurposable drugs against SARS-CoV-2 infection.
  Fangyuan Chen, Qingya Shi, Fen Pei, Andreas Vogt, Rebecca A. Porritt, Gustavo Garcia, Angela C. Gomez, Mary Hongying Cheng, Mark E. Schurdak, Bing Liu, Stephen Y. Chan...> ;Molecular Systems Biology. 2021 Aug 1
• 5 citations
  Quantifying the progression of non-alcoholic fatty liver disease in human biomimetic liver microphysiology systems with fluorescent protein biosensors.
  Manush Saydmohammed, Anupma Jha, Vineet Mahajan, Dillon C. Gavlock, Tong Ying Shun, Richard DeBiasio, Daniel E. Lefever, Xiang Li, Celeste E. Reese, Erin E. Kershaw, V...> ;Experimental Biology and Medicine. 2021 May 6
• 44 citations
  Human biomimetic liver microphysiology systems in drug development and precision medicine
  Albert Gough, Alejandro Soto-Gutierrez, Lawrence Vernetti, Mo R. Ebrahimkhani, Andrew M. Stern, D. Lansing Taylor> ;Nature Reviews. Gastroenterology & Hepatology. 2021 Apr 1
• 14 citations
  Spatial domain analysis predicts risk of colorectal cancer recurrence and infers associated tumor microenvironment networks
  Shikhar Uttam, Andrew M. Stern, Christopher J. Sevinsky, Samantha A. Furman, Filippo Pullara, Daniel Spagnolo, Luong Nguyen, Albert Gough, Fiona Ginty, D. Lansing Tayl...> ;Nature Communications. 2020 Jul 14
• 9 citations
  Targeting NAD+ Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance.
  Esther P. Jane, Daniel R. Premkumar, Swetha Thambireddy, Brian Golbourn, Sameer Agnihotri, Kelsey C. Bertrand, Stephen C. Mack, Max I. Myers, Ansuman Chattopadhyay, D....> ;Molecular Cancer Research. 2020 Jan 1
• 13 citations
  Modeling the Effect of the Metastatic Microenvironment on Phenotypes Conferred by Estrogen Receptor Mutations Using a Human Liver Microphysiological System.
  Mark T. Miedel, Dillon C. Gavlock, Shanhang Jia, Albert Gough, D. Lansing Taylor, Andrew M. Stern> ;Scientific Reports. 2019 Jun 6
• 16 citations
  Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology.
  D. Lansing Taylor, Albert Gough, Mark E. Schurdak, Lawrence Vernetti, Chakra Chennubhotla, Daniel E. Lefever, Fen Pei, James R. Faeder, Timothy R. Lezon, Andrew M. Ste...> ;Handbook of Experimental Pharmacology. 2019 Jan 1
• 4 citations
  Retraction Note: Selective killing of cancer cells by a small molecule targeting the stress response to ROS
  Lakshmi Raj, Takao Ide, Aditi U. Gurkar, Michael Foley, Monica Schenone, Xiaoyu Li, Nicola Tolliday, Todd R. Golub, Steven A. Carr, Alykhan F. Shamji, Andrew M. Stern,...> ;Nature. 2018 Sep 1
• 2 citations
  A Quantitative Systems Pharmacology Approach to Infer Pathways Involved in Complex Disease Phenotypes.
  Mark E. Schurdak, Fen Pei, Timothy R. Lezon, Diane L. Carlisle, Robert M. Friedlander, D. Lansing Taylor, Andrew M. Stern> ;Methods in Molecular Biology. 2018 Jan 1
• 14 citations
  Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes.
  Shanhang Jia, Mark T. Miedel, Marilyn Ngo, Ryan Hessenius, Ning Chen, Peilu Wang, Amir Bahreini, Zheqi Li, Zhijie Ding, Tong Ying Shun, Daniel M. Zuckerman, D. Lansing...> ;Oncology. 2018 Jan 1
• 14 citations
  Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington's Disease Model through the Application of Quantitative Systems Pharmacology.
  Fen Pei, Hongchun Li, Mark J. Henderson, Steve Titus, Ajit Jadhav, Anton Simeonov, Murat Can Cobanoglu, Seyed H Mousavi, Tongying Shun, Lee Apostle Mcdermott, Prema Iy...> ;Scientific Reports. 2017 Dec 19
• 12 citations
  Platform for Quantitative Evaluation of Spatial Intratumoral Heterogeneity in Multiplexed Fluorescence Images
  Daniel Spagnolo, Yousef Al-Kofahi, Peihong Zhu, Timothy R. Lezon, Albert Gough, Andrew M. Stern, Adrian V. Lee, Fiona Ginty, Brion Daryl Sarachan, D. Lansing Taylor, C...> ;Cancer Research. 2017 Nov 1
• 94 citations
  Mutation site and context dependent effects of ESR1 mutation in genome-edited breast cancer cell models
  Amir Bahreini, Zheqi Li, Peilu Wang, Kevin M. Levine, Nilgun Tasdemir, Lan Cao, Hazel M. Weir, Shannon Puhalla, Nancy E. Davidson, Andrew M. Stern, David Chu, Ben Ho P...> ;Breast Cancer Research. 2017 May 23
• 35 citations
  Biologically Relevant Heterogeneity: Metrics and Practical Insights.
  Albert Gough, Andrew M. Stern, John Maier, Timothy R. Lezon, Tongying Shun, Chakra Chennubhotla, Mark E. Schurdak, Steven Haney, D. Lansing Taylor> ;SLAS Discovery. 2017 Mar 1
• 15 citations
  Discovery of 8-Membered Ring Sulfonamides as Inhibitors of Oncogenic Mutant Isocitrate Dehydrogenase 1
  Jason M. Law, Sebastian C. Stark, Ke Liu, Norah E. Liang, Mahmud M. Hussain, Matthias Leiendecker, Daisuke Ito, Oscar Verho, Andrew M. Stern, Stephen Johnston, Yan-Lin...> ;ACS Medicinal Chemistry Letters. 2016 Aug 31
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