AndrewAWilsonMD

PubMed

• 1 citations
  Identification of a distal enhancer regulating hedgehog interacting protein gene in human lung epithelial cells.
  Feng Guo, Li Zhang, Yuzhen Yu, Lu Gong, Shiyue Tao, Rhiannon B Werder, Shreya Mishra, Yihan Zhou, Wardatul Jannat Anamika, Taotao Lao, Hiroyuki Inuzuka, Yihan Zhang, B...> ;Ebiomedicine. 2024 Mar 1
• Pulmonary Cellular Toxicity in Alpha-1 Antitrypsin Deficiency.
  Merritt, C., Basil, M., Lin, S., Morley, M., Bawa, P., Gallagher, M., Byers, D., Morrisey, E., Abo, K., Cantu, E., Wilson, A.> ;Chest. 2024 Feb 14
• The COPD GWAS gene ADGRG6 instructs function and injury response in human iPSC-derived type II alveolar epithelial cells.
  Rhiannon B Werder, Kayleigh A Berthiaume, Carly Merritt, Marissa Gallagher, Carlos Villacorta-Martin, Feiya Wang, Pushpinder Bawa, Vidhi Malik, Shawn M Lyons, Maria C ...> ;American Journal of Human Genetics. 2023 Oct 5
• 2 citations
  Human iPSC-hepatocyte modeling of alpha-1 antitrypsin heterozygosity reveals metabolic dysregulation and cellular heterogeneity.
  Joseph E Kaserman, Rhiannon B Werder, Feiya Wang, Taylor Matte, Michelle I Higgins, Mark Dodge, Jonathan Lindstrom-Vautrin, Pushpinder Bawa, Anne Hinds, Esther Bullitt...> ;Cell Reports. 2022 Dec 6
• 3 citations
  Ebola virus infection induces a delayed type I IFN response in bystander cells and the shutdown of key liver genes in human iPSC-derived hepatocytes.
  Whitney A Scoon, Liliana Mancio-Silva, Ellen L Suder, Carlos Villacorta-Martin, Jonathan Lindstrom-Vautrin, John G Bernbaum, Steve Mazur, Reed F Johnson, Judith Olejni...> ;Stem Cell Reports. 2022 Oct 11
• 3 citations
  Generating 3D Spheres and 2D Air-Liquid Interface Cultures of Human Induced Pluripotent Stem Cell-Derived Type 2 Alveolar Epithelial Cells.
  Rhiannon B Werder, Jessie Huang, Kristine M Abo, Olivia T Hix, Kasey Minakin, Konstantinos-Dionysios Alysandratos, Carly Merritt, Kayleigh Berthiaume, Andrea B Alber, ...> ;Journal of Visualized Experiments. 2022 Apr 15
• 10 citations
  Thyroid hormone signaling promotes hepatic lipogenesis through the transcription factor ChREBP.
  Arturo Mendoza, Catherine J. Tang, Jinyoung Choi, Mariana Acuña, Maya Logan, Adriana G. Martin, Lujain Al-Sowaimel, Bhavna N. Desai, Danielle Tenen, Christopher Jacobs...> ;Science Signaling. 2021 Nov 16
• 7 citations
  Adenine base editing reduces misfolded protein accumulation and toxicity in alpha-1 antitrypsin deficient patient iPSC-hepatocytes.
  Rhiannon B Werder, Joseph E. Kaserman, Packer Michael, Jonathan Lindstrom-Vautrin, Carlos Villacorta-Martin, Lauren Young, Yvonne Aratyn-Schaus, Gregoire Francine, And...> ;Molecular Therapy. 2021 Jul 1
• 7 citations
  Aberrant epithelial polarity cues drive the development of precancerous airway lesions.
  Andrew Tilston-Lunel, Sarah A. Mazzilli, Nathan M Kingston, Aleksander D. Szymaniak, Julia Hicks-Berthet, Joseph G. Kern, Kristine M. Abo, Mary E. Reid, Catalina Perdo...> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 May 4
• 16 citations
  Erratum: Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2 (Molecular Cell (2020) 80(6) (1104–1122.e9), (S1097276520308285), (10.10...
  Ryan M. Hekman, Adam J. Hume, Raghuveera Kumar Goel, Kristine M. Abo, Jessie Huang, Benjamin C. Blum, Rhiannon B. Werder, Ellen L Suder, Indranil Paul, Sadhna Phanse, ...> ;Molecular Cell. 2021 Jan 7
• 49 citations
  Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2.
  Ryan M Hekman, Adam J Hume, Raghuveera Kumar Goel, Kristine M Abo, Jessie Huang, Benjamin C Blum, Rhiannon B Werder, Ellen L Suder, Indranil Paul, Sadhna Phanse, Ahmed...> ;Molecular Cell. 2020 Dec 17
• 185 citations
  SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response
  Jessie Huang, Adam J. Hume, Kristine M. Abo, Rhiannon B. Werder, Carlos Villacorta-Martin, Konstantinos-Dionysios Alysandratos, Mary Lou Beermann, Chantelle Simone-Roa...> ;Cell Stem Cell. 2020 Dec 3
• 7 citations
  Expression of Amyloidogenic Transthyretin Drives Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease.
  Richard M. Giadone, Derek C. Liberti, Taylor Matte, Jessica D. Rosarda, Celia Torres-Arancivia, Sabrina Ghosh, Jolene K. Diedrich, Sandra Pankow, Nicholas Skvir, J. C....> ;Stem Cell Reports. 2020 Jul 30
• 11 citations
  A Highly Phenotyped Open Access Repository of Alpha-1 Antitrypsin Deficiency Pluripotent Stem Cells.
  Joseph E. Kaserman, Killian Hurley, Mark Dodge, Carlos Villacorta-Martin, Marall Vedaie, Jyh-Chang Jean, Derek C. Liberti, Marianne F. James, Michelle I. Higgins, Nora...> ;Stem Cell Reports. 2020 Jul 14
• 47 citations
  SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response.
  Jessie Huang, Adam J. Hume, Kristine M. Abo, Rhiannon B. Werder, Carlos Villacorta-Martin, Konstantinos-Dionysios Alysandratos, Mary Lou Beermann, Chantelle Simone-Roa...> ;Biorxiv. 2020 Jun 30
• 34 citations
  Human iPSC-derived alveolar and airway epithelial cells can be cultured at air-liquid interface and express SARS-CoV-2 host factors
  Kristine M. Abo, Liang Ma, Taylor Matte, Jessie Huang, Konstantinos D. Alysandratos, Rhiannon B. Werder, Aditya Mithal, Mary Lou Beermann, Jonathan Lindstrom-Vautrin, ...> ;Biorxiv. 2020 Jun 4
• 81 citations
  Reconstructed Single-Cell Fate Trajectories Define Lineage Plasticity Windows during Differentiation of Human PSC-Derived Distal Lung Progenitors
  Killian Hurley, Jun Ding, Carlos Villacorta-Martin, Michael J. Herriges, Anjali Jacob, Marall Vedaie, Konstantinos D. Alysandratos, Yuliang L. Sun, Chieh Lin, Rhiannon...> ;Cell Stem Cell. 2020 Apr 2
• 33 citations
  hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α1-antitrypsin deficiency
  Charis Patricia Segeritz, Sheikh Tamir Rashid, Miguel Cardoso de Brito, Maria Paola Serra, Adriana Ordóñez, Carola M. Morell, Joseph E. Kaserman, Pedro Madrigal, Nicho...> ;Journal of Hepatology. 2018 Jun 5
• 2 citations
  Patient-Derived Induced Pluripotent Stem Cells for Alpha-1 Antitrypsin Deficiency Disease Modeling and Therapeutic Discovery.
  Joseph E. Kaserman, Andrew A. Wilson> ;Chronic Obstructive Pulmonary Diseases. 2018 Sep 15
• 10 citations
  A library of ATTR amyloidosis patient-specific induced pluripotent stem cells for disease modelling and in vitro testing of novel therapeutics.
  Richard M. Giadone, Jessica D. Rosarda, Batbold Boldbaatar, Marianne F. James, Andrew A. Wilson, Vaishali Sanchorawala, Lawreen H. Connors, John L. Berk, R. Luke Wisem...> ;Amyloid. 2018 Jul 21
• 8 citations
  Ataluren, a New Therapeutic for Alpha-1 Antitrypsin-Deficient Individuals with Nonsense Mutations.
  Emer P. Reeves, Ciara A. O’Dwyer, Danielle M Dunlea, Mark R. Wormald, Padraig Hawkins, Mohammad Alfares, Darrell N. Kotton, Steven M. Rowe, Andrew A. Wilson, Noel G. M...> ;American Journal of Respiratory and Critical Care Medicine. 2018 Oct 15
• 15 citations
  Capacity of Pneumococci to Activate Macrophage Nuclear Factor κB: Influence on Necroptosis and Pneumonia Severity.
  Fadie T. Coleman, Matthew T. Blahna, Hirofumi Kamata, Kazuko Yamamoto, Mary C Zabinski, Igor Kramnik, Andrew A. Wilson, Darrell N. Kotton, Lee J. Quinton, Matthew R. J...> ;The Journal of Infectious Diseases. 2017 Aug 15
• 18 citations
  Activation of the c-Jun N-terminal kinase pathway aggravates proteotoxicity of hepatic mutant Z alpha1-antitrypsin.
  Nunzia Pastore, Sergio Attanasio, Barbara Granese, Raffaele Castello, Jeffrey Teckman, Andrew A. Wilson, Andrea Ballabio, Nicola Brunetti-Pierri> ;Hepatology. 2017 Jun 1
• 7 citations
  Protocol for Directed Differentiation of Human Induced Pluripotent Stem Cells (iPSCs) to a Hepatic Lineage
  Joseph E. Kaserman, Andrew A. Wilson> ;Methods in Molecular Biology. 2017 Jan 1
• 23 citations
  Glucose >200 mg/dL during Continuous Glucose Monitoring Identifies Adult Patients at Risk for Development of Cystic Fibrosis Related Diabetes
  Jennifer L. Taylor-Cousar, Jennifer S. Janssen, Alexandra Wilson, C. St. Clair, K. M. Pickard, Marion C. Jones, Sara J. Brayshaw, Cathy S. Chacon, Christine M. Barboa,...> ;Journal of Diabetes Research. 2016 Nov 24
• Join now to see all

Journal Articles

• Circulating Truncated Alpha-1 Antitrypsin Glycoprotein in Patient Plasma Retains Anti-Inflammatory Capacity  
  Andrew Wilson, MD, The Journal of Immunology