AndyJMinnMD

PubMed

• p53 promotes revival stem cells in the regenerating intestine after severe radiation injury.
  Clara Morral, Arshad Ayyaz, Hsuan-Cheng Kuo, Mardi Fink, Ioannis I Verginadis, Andrea R Daniel, Danielle N Burner, Lucy M Driver, Sloane Satow, Stephanie Hasapis, Reem...> ;Nature Communications. 2024 Apr 8
• 3 citations
  Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer.
  Danish Memon, Adam J Schoenfeld, Darwin Ye, George Fromm, Hira Rizvi, Xiang Zhang, Mohamed Reda Keddar, Divij Mathew, Kyung Jin Yoo, Jingya Qiu, Jayon Lihm, Jayalaksmi...> ;Cancer Cell. 2024 Feb 12
• Signal recovery in single cell batch integration.
  Zhaojun Zhang, Divij Mathew, Tristan Lim, Kaishu Mason, Clara Morral Martinez, Sijia Huang, E John Wherry, Katalin Susztak, Andy J Minn, Zongming Ma, Nancy R Zhang> ;Biorxiv. 2023 Sep 23
• 1 citations
  Isolation of Epithelial and Stromal Cells from Colon Tissues in Homeostasis and Under Inflammatory Conditions.
  Clara Morral, Reem Ghinnagow, Tatiana Karakasheva, Yusen Zhou, Anusha Thadi, Ning Li, Benjamin Yoshor, Gloria E Soto, Chia-Hui Chen, Daniel Aleynick, Sarah Weinbrom, M...> ;Bio-Protocol. 2023 Sep 20
• 2 citations
  RUNX1 is required in granulocyte-monocyte progenitors to attenuate inflammatory cytokine production by neutrophils.
  Alexandra U Zezulin, Daniel Yen, Darwin Ye, Elizabeth D Howell, Erica Bresciani, Jamie Diemer, Jian-Gang Ren, Mohd Hafiz Ahmad, Lucio H Castilla, Ivo P Touw, Andy J Mi...> ;Genes & Development. 2023 Jul 1
• TLR priming licenses NAIP inflammasome activation by immunoevasive ligands.
  James P Grayczyk, Marisa S Egan, Luying Liu, Emily Aunins, Meghan A Wynosky-Dolfi, Scott Canna, Andy J Minn, Sunny Shin, Igor E Brodsky> ;Biorxiv. 2023 May 4
• 28 citations
  Cancer cells resistant to immune checkpoint blockade acquire interferon-associated epigenetic memory to sustain T cell dysfunction.
  Jingya Qiu, Bihui Xu, Darwin Ye, Diqiu Ren, Shangshang Wang, Joseph L Benci, Yuanming Xu, Hemant Ishwaran, Jean-Christophe Beltra, E John Wherry, Junwei Shi, Andy J Minn> ;Nature Cancer. 2023 Jan 1
• 21 citations
  Targeting PARP11 to avert immunosuppression and improve CAR T therapy in solid tumors.
  Hongru Zhang, Pengfei Yu, Vivek S Tomar, Xiangjie Chen, Matthew J Atherton, Zhen Lu, Hong-Guang Zhang, Shifeng Li, Angelica Ortiz, Jun Gui, N Adrian Leu, Fangxue Yan, ...> ;Nature Cancer. 2022 Jul 1
• 28 citations
  The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade.
  Lisa Cucolo, Qingzhou Chen, Jingya Qiu, Yongjun Yu, Max Klapholz, Krista A Budinich, Zhaojun Zhang, Yue Shao, Igor E Brodsky, Martha S Jordan, D Gary Gilliland, Nancy ...> ;Immunity. 2022 Apr 12
• 75 citations
  The immunostimulatory RNA RN7SL1 enables CAR-T cells to enhance autonomous and endogenous immune function.
  Lexus R. Johnson, Daniel Y. Lee, Jacqueline S. Eacret, Darwin Ye, Carl H. June, Andy J. Minn> ;Cell. 2021 Sep 16
• 32 citations
  Thymic stromal lymphopoietin induces adipose loss through sebum hypersecretion.
  Ruth Choa, Junichiro Tohyama, Shogo Wada, Hu Meng, Jian Hu, Mariko Okumura, Rebecca M. May, Tanner F. Robertson, Ruth-Anne Langan Pai, Arben Nace, Christian Hopkins, E...> ;Science. 2021 Jul 30
• 51 citations
  FLASH Proton Radiotherapy Spares Normal Epithelial and Mesenchymal Tissues While Preserving Sarcoma Response.
  Anastasia Velalopoulou, Ilias V. Karagounis, Gwendolyn M. Cramer, Michele M. Kim, Giorgos Skoufos, Denisa Goia, Sarah Hagan, Ioannis I. Verginadis, Khayrullo Shoniyozo...> ;Cancer Research. 2021 Sep 15
• 10 citations
  A stratified phase I dose escalation trial of hypofractionated radiotherapy followed by ipilimumab in metastatic melanoma: long-term follow-up and final outcomes
  Amit Maity, Rosemarie Mick, Ramesh Rengan, Tara C. Mitchell, Ravi K. Amaravadi, Lynn M. Schuchter, Daniel A. Pryma, Dana Patsch, A. Maity, Andy J. Minn, Robert H. Vond...> ;Oncoimmunology. 2021 Jan 31
• 50 citations
  Cell Cycle Checkpoints Cooperate to Suppress DNA- and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses.
  Jie Chen, Shane M. Harding, Ramakrishnan Natesan, Lei Tian, Joseph L. Benci, Weihua Li, Andy J. Minn, Irfan A. Asangani, Roger A. Greenberg> ;Cell Reports. 2020 Sep 1
• 6 citations
  Combining Radiation with Immunotherapy: The University of Pennsylvania Experience
  Leo Y. Luo, Mark H. O'Hara, Tara C. Mitchell, Robert H. Vonderheide, E. John Wherry, Andy J. Minn, Amit Maity> ;Seminars in Radiation Oncology. 2020 Apr 1
• 186 citations
  Design, Implementation, and in Vivo Validation of a Novel Proton FLASH Radiation Therapy System.
  Eric S. Diffenderfer, Ioannis I. Verginadis, Michele M. Kim, Khayrullo Shoniyozov, Anastasia Velalopoulou, Denisa Goia, Mary E. Putt, Sarah Hagan, Stephen Avery, K. Te...> ;International Journal of Radiation Oncology, Biology, Physics. 2020 Feb 1
• 27 citations
  DENDRO: genetic heterogeneity profiling and subclone detection by single-cell RNA sequencing
  Zilu Zhou, Bihui Xu, Andy J. Minn, Nan Zhang> ;Genome Biology. 2020 Jan 14
• 232 citations
  Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade
  , , , , , , , , , , , , , , , > ;Cell. 2019 Aug 8
• 5 citations
  Correction to: Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop
  Davide Bedognetti, Michele Ceccarelli, Lorenzo Galluzzi, Rongze Lu, Karolina Palucka, Josue Samayoa, Stefani Spranger, Sarah Warren, Kwok-Kin Wong, Elad Ziv, Diego Cho...> ;Journal for Immunotherapy of Cancer. 2019 Jul 4
• 56 citations
  Toward a comprehensive view of cancer immune responsiveness: A synopsis from the SITC workshop
  Davide Bedognetti, Michele Ceccarelli, Lorenzo Galluzzi, Rongze Lu, Karolina Palucka, Josue Samayoa, Stefani Spranger, Sarah Warren, Kwok-Kin Wong, Elad Ziv, Diego Cho...> ;Journal for Immunotherapy of Cancer. 2019 May 22
• 27 citations
  p27 transcriptionally coregulates cJun to drive programs of tumor progression
  Hyunho Yoon, Minsoon Kim, Kibeom Jang, Miyoung Shin, Alexandra H. Besser, Xue Xiao, Dekuang Zhao, Seth A. Wander, Karoline J. Briegel, Lluis Morey, Andy J. Minn, Joyce...> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Apr 2
• 114 citations
  An Interferon-Driven Oxysterol-Based Defense against Tumor-Derived Extracellular Vesicles.
  Angelica Ortiz, Jun Gui, Farima Zahedi, Pengfei Yu, Christina Cho, Sabyasachi Bhattacharya, Christopher J. Carbone, Qiujing Yu, Kanstantsin V. Katlinski, Yuliya V. Kat...> ;Cancer Cell. 2019 Jan 14
• 72 citations
  A phase I trial of pembrolizumab with hypofractionated radiotherapy in patients with metastatic solid tumours.
  Amit Maity, Rosemarie Mick, Alexander C. Huang, Sangeeth M. George, Michael D. Farwell, John N. Lukens, Abigail T. Berman, Tara C. Mitchell, Josh Bauml, Lynn M. Schuch...> ;British Journal of Cancer. 2018 Oct 15
• 69 citations
  Radiotherapy and CD40 activation separately augment immunity to checkpoint blockade in cancer
  Andrew J. Rech, Hannah Dada, Jonathan J. Kotzin, Jorge Henao-Mejia, Andy J. Minn, Christina Twyman-Saint Victor, Robert H. Vonderheide> ;Cancer Research. 2018 Aug 1
• 356 citations
  Combination Cancer Therapy with Immune Checkpoint Blockade: Mechanisms and Strategies.
  Shetal A. Patel, Andy J. Minn> ;Immunity. 2018 Mar 20
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