
Aneesh Bhim Singhal MD
Vascular Neurology
Director, Massachusetts General Hospital Comprehensive Stroke Center; Lee H. Schwamm MD Board-Designated Endowed Chair in Innovation, Technology and Stroke Research; PI, New England Regional Coordinating Center for NIH StrokeNet; Associate Professor of Neurology, Harvard Medical School
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15 Parkman StWang 835Boston, MA 02114
Phone+1 617-726-8459
Fax+1 617-726-5043
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Summary
- Dr. Aneesh B. Singhal is Director of the Comprehensive Stroke Center, and the Lee H. Schwamm, MD Board-Designated Endowed Chair in Innovation, Technology and Stroke Research at Massachusetts General Hospital (MGH), Boston, USA. He is Principal Investigator of the New England Regional Coordinating Center (NERCC) for the NIH-funded stroke clinical trials network StrokeNet. He is an elected Fellow to the American Neurological Association, the American Academy of Neurology, and the American Heart Association. He is Past President of the Association of Indian Neurologists in USA. He is on the Board of Neurology Foundation India and Medical Advisor to OpenEvidence.Com. Dr. Singhal co-directs the Clinical Trials module of the Harvard Medical School Master of Medical Sciences in Clinical Investigation (MMSCI) program and teaches in several other HMS courses. His areas of research include stroke clinical trials, stroke in young adults, cerebral arteriopathies, advanced brain imaging for acute ischemic stroke, and stroke neuroprotection. He is internationally recognized for his work on the role of normobaric oxygen therapy in acute stroke, and for characterizing stroke syndromes such as the reversible cerebral vasoconstriction syndrome (RCVS), primary angiitis of the central nervous system (PACNS), and post-stroke recrudescence (PSR). He has developed numerous innovative clinical care pathways and guidelines, for which he received the 2023 Quality Innovation Award from the American Academy of Neurology. Dr. Singhal has hosted observers from nearly 50 countries, many of whom are now stroke leaders in their home countries. He has served as the Principal Investigator of several NIH and Industry funded stroke clinical trials. Dr. Singhal has authored or co-authored over 300 articles and book chapters.
Education & Training
- Mass General Brigham/Massachusetts General Hospital/Brigham and Women's Hospital/Harvard Medical SchoolFellowship, Vascular Neurology, 1999 - 2001
- Mass General Brigham/Brigham and Women's Hospital/Massachusetts General Hospital/Harvard Medical SchoolResidency, Neurology, 1995 - 1999
- BYL Nair Charitable HospitalMD, Internal Medicine, 1992 - 1995
- Seth G.S. Medical CollegeClass of 1992
Certifications & Licensure
- MA State Medical License 1998 - 2027
- ME State Medical License 2011 - 2026
- MO State Medical License 2022 - 2026
- NY State Medical License 2023 - 2026
- KS State Medical License 2022 - 2025
- NH State Medical License 2011 - 2025
- FL State Medical License 1999 - 2005
- American Board of Psychiatry and Neurology Neurology
- American Board of Psychiatry and Neurology Vascular Neurology
Clinical Trials
- Normobaric Oxygen Therapy in Acute Ischemic Stroke Trial Start of enrollment: 2007 Jan 01
- Normobaric Oxygen (NBO) Therapy in Acute Migraine Start of enrollment: 2012 Jul 01
- Searching for Explanations for Cryptogenic Stroke in the Young: Revealing the Etiology, Triggers, and Outcome
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Publications & Presentations
PubMed
- Endovascular management of tandem occlusions: current evidence and future directions.Neeharika Krothapalli, Jeremy J Heit, Adam de Havenon, Aneesh B Singhal, Eric Sussman
Journal of Neurointerventional Surgery. 2025-08-07 - Correction Rate Matters in Severe Hyponatremia.Harish Seethapathy, Aneesh B Singhal, Sagar U Nigwekar
JAMA Internal Medicine. 2025-08-01 - Evaluation of Door-to-Needle Times Between Alteplase and Tenecteplase for Acute Ischemic Stroke at Two Academic Medical Centers.Nicholas J Monkemeyer, Kaylee K Marino, Melanie Z Goodberlet, Christopher Anderson, Linda Bresette
The Annals of Pharmacotherapy. 2025-06-01
Journal Articles
- Case 26-2020: A 60-Year-Old Woman with Altered Mental Status and Weakness on the Left SideAneesh B Singhal, Bart K Chwalisz, Shibani S Mukerji, The New England Journal of Medicine
Lectures
- Nonatherosclerotic Vasculopathies Have Distinct CharacteristicsAmerican Stroke Association, International Stroke Conference 2014, San Diego, California, USA
- Nonatherosclerotic Vasculopathies Have Distinct CharacteristicsInternational Stroke Conference 2014, San Diego, California, USA
- Reversible Vasoconstriction Syndromes and CNS VasculitisBoston, MA - 2/12/2014
Authored Content
- Case 26-2020: A 60-Year-Old Woman with Altered Mental Status and Weakness on the Left SideAugust 2020
- Case 26-2020: A 60-Year-Old Woman with Altered Mental Status and Weakness on the Left SideAugust 2020
- Case 26-2020: A 60-Year-Old Woman with Altered Mental Status and Weakness on the Left SideAugust 2020
- Case 26-2020: A 60-Year-Old Woman with Altered Mental Status and Weakness on the Left SideAugust 2020
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Press Mentions
- ISC 2021 Session: Prognostication and Early Withdrawal of Care in Ischemic Stroke and ICHMarch 17th, 2021
- Association Between Reduced Myocardial Contraction Fraction and Cardiovascular Disease Outcomes: The Multi-Ethnic Study of AtherosclerosisApril 1st, 2020
- Clinical Features, Triggers, and Risk Factors Identified for Post-Stroke RecrudescenceSeptember 18th, 2017
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Grant Support
- New England Regional Coordinating Center for the NINDS Stroke Trials Network (StrokeNet)MASSACHUSETTS GENERAL HOSPITAL2024–2028
- NIH StrokeNet (Deputy PI, New England Regional Coordinating Center)NIH-NINDS2013–2018
- Indo-Us Collaborative Stroke Registry And Infrastructure DevelopmentNational Institute Of Neurological Disorders And Stroke2011
- Normobaric Hyperoxia In Acute Ischemic StrokeNational Institute Of Neurological Disorders And Stroke2006–2010
- Normobaric O2 In Ischemic StrokeNational Institute Of Neurological Disorders And Stroke2006–2009
Professional Memberships
- Fellow
- Fellow
- American Neurological AssociationFellow
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