AngelaEmmettaRiversMD

PubMed

• 12 citations
  An Analysis of Racial and Ethnic Backgrounds Within the CASiRe International Cohort of Sickle Cell Disease Patients: Implications for Disease Phenotype and Clinical Re...
  Andrew D. Campbell, Raffaella Colombatti, Biree Andemariam, Crawford John Strunk, Immacolata Tartaglione, Connie M. Piccone, Deepa Manwani, Eugenia Vicky Asare, Donna ...> ;Journal of Racial and Ethnic Health Disparities. 2021 Feb 1
• 2 citations
  T‐cell large granular lymphocytic leukemia successfully treated with oral cyclosporine in a child: Case report and review of literature
  Nupur Mittal, Thomas P. Loughran, Angela Rivers> ;Pediatric Blood & Cancer. 2020 Jun 26
• 14 citations
  A study of the geographic distribution and associated risk factors of leg ulcers within an international cohort of sickle cell disease patients: the CASiRe group analy...
  Charles Antwi-Boasiako, Biree Andemariam, Raffaella Colombatti, Eugenia Vicky Asare, Crawford John Strunk, Connie M. Piccone, Deepa Manwani, Donna Boruchov, Fatimah Fa...> ;Annals of Hematology. 2020 May 6
• Cognition affected in young children with serum ferritin <17 μg/L.
  Angela Rivers> ;The Journal of Pediatrics. 2020 May 1
• 6 citations
  A new target for fetal hemoglobin reactivation.
  Angela Rivers, Robert E. Molokie, Donald Lavelle> ;Haematologica. 2019 Dec 1
• 13 citations
  Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboons
  Angela Rivers, Kestis Vaitkus, Ramasamy Jagadeeswaran, Maria Armila Ruiz, Vinzon Ibanez, Filippo Ciceri, Fernando Cavalcanti, Robert E. Molokie, Yogen Saunthararajah, ...> ;Experimental Hematology. 2018 Nov 1
• 3 citations
  Potential role of LSD1 inhibitors in the treatment of sickle cell disease: a review of preclinical animal model data.
  Angela Rivers, Ramasamy Jagadeeswaran, Donald Lavelle> ;American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 2018 Oct 1
• 18 citations
  Evolving treatment paradigms in sickle cell disease.
  Ramasamy Jagadeeswaran, Angela Rivers> ;Hematology. American Society of Hematology. Education Program. 2017 Dec 8
• 45 citations
  Pharmacological inhibition of LSD1 and mTOR reduces mitochondrial retention and associated ROS levels in the red blood cells of sickle cell disease
  Ramasamy Jagadeeswaran, Benjamin Vazquez, Muthusamy Thiruppathi, Balaji B. Ganesh, Vinzon Ibanez, Shuaiying Cui, James Douglas Engel, Alan M. Diamond, Robert E. Moloki...> ;Experimental Hematology. 2017 Jun 1
• 17 citations
  Efficacy and Safety of Long-term RN-1 Treatment to Increase HbF in Baboons
  Vinzon Ibanez, Kestis Vaitkus, Angela Rivers, Robert E. Molokie, Shuaiying Cui, James Douglas Engel, Joseph DeSimone, Donald Lavelle> ;Blood. 2017 Jan 12
• 43 citations
  The LSD1 inhibitor RN-1 recapitulates the fetal pattern of hemoglobin synthesis in baboons (P. anubis).
  Angela Rivers, Kestis Vaitkus, Vinzon Ibanez, Maria Armila Ruiz, Ramasamy Jagadeeswaran, Yogen Saunthararajah, Shuaiying Cui, James Douglas Engel, Joseph DeSimone, Don...> ;Haematologica. 2016 Jun 1
• 66 citations
  The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice
  Shuaiying Cui, Kim Chew Lim, Lihong Shi, Mary P. Lee, Natee Jearawiriyapaisarn, Greggory Myers, Andrew D. Campbell, David Harro, Shigeki Iwase, Raymond C. Trievel, Ang...> ;Blood. 2015 Jul 16
• 3 citations
  Adverse Reactions to Pneumococcal Vaccine in Pediatric and Adolescent Patients with Sickle Cell Disease.
  Jin Han, Opeyemi Kemiki, Lewis L. Hsu, Angela Rivers> ;Pharmacotherapy. 2015 Jul 1
• 37 citations
  RN-1, a potent and selective lysine-specific demethylase 1 inhibitor, increases γ-globin expression, F reticulocytes, and F cells in a sickle cell disease mouse model
  Angela Rivers, Kestis Vaitkus, Maria Armila Ruiz, Vinzon Ibanez, Ramasamy Jagadeeswaran, Tatiana Kouznetsova, Joseph DeSimone, Donald Lavelle> ;Experimental Hematology. 2015 Jul 1
• 21 citations
  Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation
  Maria Armila Ruiz, Angela Rivers, Vinzon Ibanez, Kestis Vaitkus, Nadim Mahmud, Joseph A. DeSimone, Donald Lavelle> ;Epigenetics. 2015 May 1
• 37 citations
  Rationally designed capsid and transgene cassette of AAV6 vectors for dendritic cell-based cancer immunotherapy
  Jheel Pandya, Luis Ortiz, Chen Ling, Angela Rivers, George Aslanidi> ;Immunology and Cell Biology. 2014 Feb 1
• 15 citations
  Drug-Loaded Sickle Cells Programmed ex vivo for Delayed Hemolysis Target Hypoxic Tumor Microvessels and Augment Tumor Drug Delivery
  Se-woon Choe, David S. Terman, Angela Rivers, José A. Rivera, Richard Lottenberg, Brian S. Sorg> ;Journal of Controlled Release. 2013 Oct 28
• 59 citations
  Optimizing the transduction efficiency of capsid-modified AAV6 serotype vectors in primary human hematopoietic stem cells in vitro and in a xenograft mouse model in vivo
  Liujiang Song, M. Ariel Kauss, Etana Kopin, Manasa Chandra, Taihra Ul-Hasan, Erin A. Miller, Giridhara R. Jayandharan, Angela Rivers, George Aslanidi, Chen Ling, Baozh...> ;Cytotherapy. 2013 Aug 1
• 79 citations
  Optimization of the capsid of recombinant adeno-associated virus 2 (AAV2) vectors: the final threshold?
  George Aslanidi, Angela Rivers, Luis Ortiz, Liujiang Song, Chen Ling, Lakshmanan Govindasamy, Kim Van Vliet, Mengqun Tan, Mavis Agbandje-McKenna, Arun Srivastava> ;Plos One. 2013 Mar 19
• 38 citations
  High-efficiency transduction of human monocyte-derived dendritic cells by capsid-modified recombinant AAV2 vectors
  George Aslanidi, Angela Rivers, Luis Ortiz, Lakshmanan Govindasamy, Chen Ling, Giridhara R. Jayandharan, Sergei Zolotukhin, Mavis Agbandje-McKenna, Arun Srivastava> ;Vaccine. 2012 Jun 6
• 28 citations
  Optimized adeno-associated virus (AAV)-protein phosphatase-5 helper viruses for efficient liver transduction by single-stranded AAV vectors: therapeutic expression of ...
  Giridhara R. Jayandharan, Li Zhong, Brandon K. Sack, Angela Rivers, Mengxin Li, Baozheng Li, Roland W. Herzog, Arun Srivastava> ;Human Gene Therapy. 2010 Jan 21
• 8 citations
  Congenital cytopenias and bone marrow failure syndromes.
  Angela Rivers, William B. Slayton> ;Seminars in Perinatology. 2009 Feb 1
• 7 citations
  Type 2B von Willebrand disease associated with the release of platelet agglutinates from megakaryocytes in the bone marrow.
  William B. Slayton, Milin Patel, Martha Sola-Visner, Neil S. Harris, Angela Rivers, Robert R. Montgomery, Kenneth D. Friedman> ;Journal of Pediatric Hematology/oncology. 2008 Sep 1
• 10 citations
  Optimization of Recombinant Adeno-Associated Viral Vectors for Human β-Globin Gene Transfer and Transgene Expression
  Njeri Maina, Li Zhong, Xiaomiao Li, Weihong Zhao, Zongchao Han, Daniela Bischof, George Aslanidi, Sergei Zolotukhin, Kirsten A. Weigel-Van Aken, Angela Rivers, William...> ;Human Gene Therapy. 2008 Apr 1
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Abstracts/Posters

• An Analysis of Racial and Ethnic Backgrounds within the Casire International Cohort of Sickle Cell Disease Patients: Implications for Disease Phenotype and Clinical Re...
  Angela Rivers, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019

Lectures

• The LSD1 Inhibitor RN-1 Increases I-Globin Expression in Baboons By Targeting an Early Event Responsible for I-Globin Repression 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018