AnilKChandrakerMD

Nephrology • Boston, MA

Kidney & Pancreas Transplantation

Associate Professor, Medicine, Harvard Medical School

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Office
75 Francis Street
Brigham And Women's Hospital Renal Division
Boston, MA 02115
Phone+1 617-732-7412
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Education & Training

Brigham and Women's Hospital/Massachusetts General HospitalFellowship, Nephrology, 1995 - 1999
University of Glasgow Faculty of MedicineClass of 1987

Certifications & Licensure

MA State Medical License 1999 - 2024

Awards, Honors, & Recognition

President American Society of Transplantation, 2016-2017
Fellow (ASNF) American Society of Nephrology

Clinical Trials

Rituximab in Renal Allograft Recipients Who Develop Early De Novo Anti-HLA Alloantibodies Start of enrollment: 2006 Mar 01
Completed
Phase 2
BK Treatment Study Start of enrollment: 2009 Feb 01
Completed
Phase 4
Prevention of Cardiac Allograft Vasculopathy Using Rituximab (Rituxan) Therapy in Cardiac Transplantation Start of enrollment: 2011 Sep 01
Terminated
Phase 2
Effect of Short Term Aliskiren Treatment in Kidney Transplant Patients Start of enrollment: 2010 Apr 01
Terminated
Phase 4
APOL1 Gene Variants in African American Kidney Transplant Recipients Start of enrollment: 2014 Apr 01
Terminated
Associating Renal Transplantation With the ITN Signature of Tolerance Start of enrollment: 2010 Sep 01
Completed
Immune Monitoring and CNI Withdrawal in Low Risk Recipients of Kidney Transplantation Start of enrollment: 2010 Nov 01
Terminated
Phase 2
Efficacy and Safety of Eculizumab for Treatment of Antibody-mediated Rejection Following Renal Transplantation Start of enrollment: 2013 Nov 01
Terminated
Phase 2
Retrospective Multicenter Study to Determine 4-Year Clinical Outcomes in Subjects Previously Enrolled in the CTOT-05 Study Start of enrollment: 2014 Oct 01
Completed
Ultra-low Dose Subcutaneous IL-2 in Renal Transplantation Start of enrollment: 2015 Sep 01
Terminated
Phase 1, Phase 2
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Publications & Presentations

PubMed

Adoptive Immune Effector Cell Therapies in Cancer and Solid Organ Transplantation: A Review.
Sudipta Tripathi, Brittany Schreiber, Sarah Nikiforow, Anil Chandraker> ;Seminars in Nephrology. 2024 Mar 29
1 citations
Cemiplimab for Kidney Transplant Recipients With Advanced Cutaneous Squamous Cell Carcinoma.
Glenn J Hanna, Harita Dharanesswaran, Anita Giobbie-Hurder, John J Harran, Zixi Liao, Lori Pai, Vatche Tchekmedyian, Emily S Ruiz, Abigail H Waldman, Chrysalyne D Schm...> ;Journal of Clinical Oncology. 2024 Mar 20
1 citations
Comparative Effectiveness of PET and SPECT MPI for Predicting Cardiovascular Events After Kidney Transplant.
Daniel M Huck, Brittany Weber, Brittany Schreiber, Jay Pandav, Sean Parks, Jon Hainer, Jenifer M Brown, Sanjay Divakaran, Ron Blankstein, Sharmila Dorbala, Ludovic Tri...> ;Circulation. Cardiovascular Imaging. 2024 Jan 1
Post-transplant recurrence of focal segmental glomerular sclerosis: consensus statements.
Raina, R., Jothi, S., Haffner, D., Somers, M., Filler, G., Vasistha, P., Chakraborty, R., Shapiro, R., Randhawa, P., Parekh, R., Licht, C., Bunchman, T., Sethi, S., Ma...> ;Kidney International. 2024 Mar 1
1 citations
Targeting pharmacotherapies for inflammatory and cardiorenal endpoints in kidney disease.
Daniel M Huck, Leo F Buckley, Anil Chandraker, Ron Blankstein, Brittany Weber> ;Journal of Cardiovascular Pharmacology. 2023 Sep 5
Cytokine modulation in abdominal septic shockthe crucial role of IL-6 signaling in endothelial dysfunction.
Takuya Ueno, Toshiaki Ikeda, Masaaki Okihara, Isao Akashi, Takayoshi Yokoyama, Yu Kihara, Osamu Konno, Yuki Nakamura, Hitoshi Iwamoto, Yu Ueno, Anil Chandraker> ;Frontiers in Medicine. 2023 Jan 1
1 citations
Lack of Efficacy and Safety of Eculizumab for Treatment of Antibody-Mediated Rejection Following Renal Transplantation.
Sujung Heo, Youngchan Park, Nagyeom Lee, Yanghyeon Kim, Ye Na Kim, Ho Sik Shin, Yeonsoon Jung, Hark Rim, Helmut G Rennke, Anil Chandraker> ;Transplantation Proceedings. 2022 Oct 1
9 citations
Inpatient Kidney Palliative Care for Kidney Transplant Recipients With Failing Allografts.
Naoka Murakami, Samantha L Gelfand, Kate R Sciacca, Kelsey Killeen, Richard E Leiter, Joel T Adler, Anil K Chandraker, Joshua R Lakin> ;Kidney Medicine. 2022 Feb 1
Introduction: Moving Toward a More Personalized Approach to Kidney Transplantation.
Anil Chandraker> ;Seminars in Nephrology. 2022 Jan 1
5 citations
Impact of Post-Transplantation Hypomagnesemia on Long-Term Graft and Patient Survival after Transplantation.
Ofer Isakov, Bhanu K Patibandla, Anil Chandraker, Tammy Hod, Kenneth B Christopher> ;Kidney & Blood Pressure Research. 2022 Jan 1
2 citations
Adenosinergic Pathway and Linked Suppression: Two Critical Suppressive Mechanisms of Human Donor Antigen Specific Regulatory T Cell Lines Expanded Post Transplant.
Sudipta Tripathi, Paloma L Martin-Moreno, George Kavalam, Brittany L Schreiber, Ana Maria Waaga-Gasser, Anil Chandraker> ;Frontiers in Immunology. 2022 Jan 1
8 citations
The clinical value of donor-derived cell-free DNA measurements in kidney transplantation.
Neetika Garg, Didier A. Mandelbrot, Sandesh Parajuli, Fahad Aziz, Brad C. Astor, Anil Chandraker, Arjang Djamali> ;Transplantation Reviews. 2021 Dec 1
77 citations
Discovery of Autoantibodies Targeting Nephrin in Minimal Change Disease Supports a Novel Autoimmune Etiology
Andrew J. R. Watts, Keith Keller, Gabriel Lerner, Ivy A. Rosales, A. B. Collins, Miroslav Sekulic, Sushrut S. Waikar, Anil Chandraker, Leonardo V. Riella, Mariam P. Al...> ;Journal of the American Society of Nephrology. 2021 Nov 3
2 citations
Human leukocyte antigen antibody sensitization, lung transplantation, and health equity.
Andrew M. Courtwright, Namrata Patel, Anil Chandraker, Hilary J. Goldberg> ;American Journal of Transplantation. 2021 Aug 23
8 citations
Obesity and Post-Transplant Diabetes Mellitus in Kidney Transplantation
Paloma L Martin-Moreno, Ho-Sik Shin, Anil Chandraker> ;Journal of Clinical Medicine. 2021 Jun 5
20 citations
Full Facial Retransplantation in a Female Patient – Technical, Immunologic and Clinical Considerations
Adriana C. Panayi, Ali-Farid Safi, Valentin Haug, Bridget Perry, Branislav Kollar, Marie-Christine Nizzi, Justin M. Broyles, Donald J. Annino, Francisco M. Marty, Indr...> ;American Journal of Transplantation. 2021 May 25
9 citations
Immunoregulatory and lipid presentation pathways are upregulated in human face transplant rejection.
William J Crisler, Beatrice Dyring-Andersen, Jessica E. Teague, Qian Zhan, Victor Barrera, Shannan J. Ho Sui, Sotirios Tasigiorgos, Naoka Murakami, Anil Chandraker, St...> ;The Journal of Clinical Investigation. 2021 Apr 15
35 citations
Discovery and Validation of a Urinary Exosome mRNA Signature for the Diagnosis of Human Kidney Transplant Rejection
Rania El Fekih, James Hurley, Vasisht Tadigotla, Areej Alghamdi, Anand Srivastava, Christine M. Coticchia, John Choi, Hazim Allos, Karim M. Yatim, Juliano B. Alhaddad,...> ;Journal of the American Society of Nephrology. 2021 Mar 3
12 citations
Combined Immunotherapy With Belatacept and BTLA Overexpression Attenuates Acute Rejection Following Kidney Transplantation.
Hengcheng Zhang, Zijie Wang, Jiayi Zhang, Zeping Gui, Zhijian Han, Jun Tao, Hao Chen, Li Sun, Shuang Fei, Haiwei Yang, Ruoyun Tan, Anil Chandraker, Min Gu> ;Frontiers in Immunology. 2021 Feb 24
25 citations
Follicular T cells Mediate Donor Specific Antibody and Rejection after Solid Organ Transplantation
Mostafa T. Mohammed, Songjie Cai, Benjamin L. Hanson, Hengcheng Zhang, Rachel L. Clement, Joe Daccache, Cecilia B Cavazzoni, Bruce R. Blazar, Alessandro Alessandrini, ...> ;American Journal of Transplantation. 2021 Jan 9
5 citations
Posttransplantation Hypomagnesemia as a Predictor of Better Graft Function after Transplantation.
Tammy Hod, Ofer Isakov, Bhanu K. Patibandla, Kenneth B. Christopher, Rami Hershkoviz, Idit F. Schwartz, Anil Chandraker> ;Kidney & Blood Pressure Research. 2020 Nov 5
25 citations
Donor myeloid derived suppressor cells (MDSCs) prolong allogeneic cardiac graft survival through programming of recipient myeloid cells in vivo
Songjie Cai, John Choi, Thiago J. Borges, Hengcheng Zhang, Ji Miao, Takaharu Ichimura, Xiaofei Li, Simiao Xu, Philip Chu, Siawosh K. Eskandari, Hazim Allos, Juliano B....> ;Scientific Reports. 2020 Aug 28
17 citations
The association of calcium oxalate deposition in kidney allografts with graft and patient survival
Ragnar Palsson, Anil Chandraker, Gary C. Curhan, Helmut G. Rennke, Gearoid M. McMahon, Sushrut S. Waikar> ;Nephrology, Dialysis, Transplantation. 2020 May 1
10 citations
High-mobility group box 1 protein antagonizes the immunosuppressive capacity and therapeutic effect of mesenchymal stem cells in acute kidney injury
Shuo Wang, Songjie Cai, Weitao Zhang, Xigao Liu, Yan Li, Chao Zhang, Yigang Zeng, Ming Xu, Ruiming Rong, Tianshu Yang, Benkang Shi, Anil Chandraker, Cheng Yang, Tongyu...> ;Journal of Translational Medicine. 2020 Apr 20
3 citations
Immunologic Risk Assessment and Approach to Immunosuppression Regimen in Kidney Transplantation
John Choi, Anil Chandraker> ;Clinics in Laboratory Medicine. 2019 Dec 1
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Lectures

The Brigham Renal Board Review Course
Harvard Medical School, Boston, Massachusetts - 8/6/2012

Press Mentions

AlloVir Reports Full-Year 2022 Financial Results and 2023 OutlookFebruary 17th, 2023
AlloVir Reports Blinded, Preliminary, Phase 2 Data Supporting the Ongoing Study of Posoleucel, a Multi-Virus-Specific T Cell Therapy, for the Treatment of BK Viremia in Kidney Transplant RecipientsJune 7th, 2022
Two Brigham Scientists Honored for Their Work on Gene and Cell TherapiesMay 9th, 2022
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