AnnThorMD

PubMed

• Thyroid hormone enhances estrogen-mediated proliferation and cell cycle regulatory pathways in steroid receptor-positive breast Cancer.
  Reema S Wahdan-Alaswad, Susan M Edgerton, Hyun Min Kim, Aik Choon Tan, Bryan R Haugen, Bolin Liu, Ann D Thor> ;Cell Cycle. 2023 Sep 18
• HER3 functions as an effective therapeutic target in triple negative breast cancer to potentiate the antitumor activity of gefitinib and paclitaxel.
  Hui Lyu, Fei Shen, Sanbao Ruan, Congcong Tan, Jundong Zhou, Ann D Thor, Bolin Liu> ;Cancer Cell International. 2023 Sep 16
• 1 citations
  Gender differences in appointments to pathology department interim chair positions and subsequent advancement to permanent chair positions.
  Mary F Lipscomb, Nancy E Joste, Madeleine Markwood, David N Bailey, Donna E Hansel, Merce Jorda, Debra G B Leonard, Deborah Powell, Amyn M Rojiani, Sandra J Shin, Ann ...> ;Academic Pathology. 2023 Apr 24
• 5 citations
  Preventing ovariectomy-induced weight gain decreases tumor burden in rodent models of obesity and postmenopausal breast cancer.
  Elizabeth A Wellberg, Karen A Corleto, L Allyson Checkley, Sonali Jindal, Ginger Johnson, Janine A Higgins, Sarina Obeid, Steven M Anderson, Ann D Thor, Pepper J Sched...> ;Breast Cancer Research. 2022 Jun 20
• 8 citations
  Upregulation of endogenous TRAIL-elicited apoptosis is essential for metformin-mediated antitumor activity against TNBC and NSCLC.
  Shuang Liu, Erik V. Polsdofer, Lukun Zhou, Sanbao Ruan, Hui Lyu, Defu Hou, Hao Liu, Ann D. Thor, Zhimin He, Bolin Liu> ;Molecular Therapy Oncolytics. 2021 Apr 29
• 6 citations
  Exogenous Thyroid Hormone Is Associated with Shortened Survival and Upregulation of High-Risk Gene Expression Profiles in Steroid Receptor-Positive Breast Cancers.
  Reema Wahdan-Alaswad, Susan M. Edgerton, Hiba Salem, Hyunmin Kim, Aik Choon Tan, Jessica Finlay-Schultz, Elizabeth A. Wellberg, Carol A. Sartorius, Britta M. Jacobsen,...> ;Clinical Cancer Research. 2021 Jan 15
• 4 citations
  AIDS-related Cryptococcus neoformans choroiditis.
  Gregory S Canfield, Sarah Reingold, Andrea P. Ho, Ann D. Thor, Paula E. Pecen, Kristen DeSanto, Daniel B Chastain, Carlos Franco-Paredes, Jose R Castillo-Mancilla, And...> ;Idcases. 2020 Aug 8
• 6 citations
  ETS transcription factor ESE-1/Elf3 is an independent prognostic factor of survival in HR + HER2 + breast cancer patients
  Adwitiya Kar, Karen Koto, Darius M. Walker, Tammy Trudeau, Susan M. Edgerton, Ann D. Thor, Arthur Gutierrez-Hartmann> ;Breast Cancer Research and Treatment. 2020 Jun 19
• 9 citations
  Targeted lapatinib anti-HER2/ErbB2 therapy resistance in breast cancer: opportunities to overcome a difficult problem.
  Reema Wahdan-Alaswad, Bolin Liu, Ann D Thor> ;Cancer Drug Resistance. 2020 Jan 1
• 30 citations
  FGFR1 underlies obesity-associated progression of estrogen receptor–positive breast cancer after estrogen deprivation
  Elias, A., , , , , , , , , , , , , , , , , , > ;JCI Insight. 2018 Jul 25
• 34 citations
  Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer
  Erin D. Giles, Sonali Jindal, Elizabeth A. Wellberg, Troy Schedin, Steven M. Anderson, Ann D. Thor, Dean P. Edwards, Paul S. MacLean, Pepper Schedin> ;Breast Cancer Research. 2018 Jun 14
• 16 citations
  Ganetespib targets multiple levels of the receptor tyrosine kinase signaling cascade and preferentially inhibits ErbB2-overexpressing breast cancer cells.
  Harry Lee, Nipun Saini, Erin W. Howard, Amanda B. Parris, Zhikun Ma, Qingxia Zhao, Ming Zhao, Bolin Liu, Susan M. Edgerton, Ann D. Thor, Xiaohe Yang> ;Scientific Reports. 2018 May 1
• 38 citations
  Metformin Targets Glucose Metabolism in Triple Negative Breast Cancer.
  Reema Wahdan-Alaswad, Susan M. Edgerton, HS Salem, Ann D. Thor> ;Journal of Oncology Translational Research. 2018 Mar 21
• 22 citations
  Development of Novel Patient-Derived Xenografts from Breast Cancer Brain Metastases.
  Maria J. Contreras-Zarate, D. Ryan Ormond, Austin E. Gillen, Colton Hanna, Nicole L. Day, Natalie J. Serkova, Britta M. Jacobsen, Susan M. Edgerton, Ann D. Thor, Virgi...> ;Frontiers in Oncology. 2017 Nov 2
• 11 citations
  The Androgen Receptor Supports Tumor Progression After the Loss of Ovarian Function in a Preclinical Model of Obesity and Breast Cancer.
  Elizabeth A. Wellberg, L. Allyson Checkley, Erin D. Giles, Stevi J. Johnson, Robera Oljira, Reema Wahdan-Alaswad, Rebecca M. Foright, Greg Dooley, Susan M. Edgerton, S...> ;Hormones & Cancer. 2017 Jul 24
• 11 citations
  Activation of cancerous inhibitor of PP2A (CIP2A) contributes to lapatinib resistance through induction of CIP2A-Akt feedback loop in ErbB2-positive breast cancer cells
  Ming Zhao, Erin W. Howard, Amanda B. Parris, Zhiying Guo, Qingxia Zhao, Zhikun Ma, Ying Xing, Bolin Liu, Susan M. Edgerton, Ann D. Thor, Xiaohe Yang> ;Oncotarget. 2017 Jul 19
• 33 citations
  Metformin Accumulation Correlates with Organic Cation Transporter 2 Protein Expression and Predicts Mammary Tumor Regression In Vivo.
  L. Allyson Checkley, Michael C. Rudolph, Elizabeth A. Wellberg, Erin D. Giles, Reema Wahdan-Alaswad, Julie A. Houck, Susan M. Edgerton, Ann D. Thor, Pepper Schedin, St...> ;Cancer Prevention Research. 2017 Feb 2
• 58 citations
  Metformin attenuates transforming growth factor beta (TGF-β) mediated oncogenesis in mesenchymal stem-like/claudin-low triple negative breast cancer.
  Reema Wahdan-Alaswad, Harrell Jc, Zeying Fan, Susan M. Edgerton, Bolin Liu, Ann D. Thor> ;Cell Cycle. 2016 Feb 26
• 9 citations
  Genome-wide functional genetic screen with the anticancer agent AMPI-109 identifies PRL-3 as an oncogenic driver in triple-negative breast cancers
  Hamid H. Gari, Christy M. Gearheart, Susan Fosmire, Gregory D. Degala, Zeying Fan, Kathleen C. Torkko, Susan M. Edgerton, M. Scott Lucia, Rahul Ray, Ann D. Thor, Chris...> ;Oncotarget. 2016 Feb 17
• 21 citations
  The erbB3- and IGF-1 receptor-initiated signaling pathways exhibit distinct effects on lapatinib sensitivity against trastuzumab-resistant breast cancer cells
  Hui Lyu, Xiao He Yang, Susan M. Edgerton, Ann D. Thor, Xiaoying Wu, Zhimin He, Bolin Liu> ;Oncotarget. 2016 Jan 19
• 29 citations
  Pilot trial of paclitaxel-trastuzumab adjuvant therapy for early stage breast cancer: a trial of the ECOG-ACRIN cancer research group (E2198)
  Bryan P. Schneider, Anne O'Neill, Fei Shen, George W. Sledge, Ann D. Thor, Stephen P. Kahanic, Paul J. Zander, Nancy E. Davidson> ;British Journal of Cancer. 2015 Dec 22
• 10 citations
  Sex Differences in Workplace Satisfaction and Engagement of Academic Pathologists: Opportunities to Enhance Faculty Diversity.
  Lydia P. Howell, Mary Lipscomb Lyons, Ann D. Thor, Valerie Dandar> ;Archives of Pathology & Laboratory Medicine. 2015 Dec 15
• 10 citations
  Increased erbB3 promotes erbB2/neu-driven mammary tumor proliferation and co-targeting of erbB2/erbB3 receptors exhibits potent inhibitory effects on breast cancer cells
  Hui Lyu, Jingcao Huang, Susan M. Edgerton, Ann D. Thor, Zhimin He, Bolin Liu> ;International Journal of Clinical and Experimental Pathology. 2015 Jun 1
• 76 citations
  Metformin-Induced Killing of Triple Negative Breast Cancer Cells is Mediated by Reduction in Fatty Acid Synthase via miRNA-193b
  Reema Wahdan-Alaswad, Dawn R. Cochrane, Nicole S. Spoelstra, Erin N. Howe, Susan M. Edgerton, Steven M. Anderson, Ann D. Thor, Jennifer K. Richer> ;Hormones & Cancer. 2014 Sep 12
• 60 citations
  Postpartum breast involution reveals regression of secretory lobules mediated by tissue-remodeling.
  Sonali Jindal, Dexiang Gao, Pat Bell, Grethe Albrektsen, Susan M. Edgerton, Christine B. Ambrosone, Ann D. Thor, Virginia F. Borges, Pepper Schedin> ;Breast Cancer Research. 2014 Mar 28
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