AnnaMae ElizaDiehlMD

PubMed

• A humanized mouse model for adeno-associated viral gene therapy.
  Mercedes Barzi, Tong Chen, Trevor J Gonzalez, Francis P Pankowicz, Seh Hoon Oh, Helen L Streff, Alan Rosales, Yunhan Ma, Sabrina Collias, Sarah E Woodfield, Anna Mae D...> ;Nature Communications. 2024 Mar 4
• Alterations in zonal distribution and plasma membrane localization of hepatocyte bile acid transporters in patients with NAFLD.
  William A Murphy, Anna Mae Diehl, Matthew Shane Loop, Dong Fu, Cynthia D Guy, Manal F Abdelmalek, Georgia Sofia Karachaliou, Noora Sjöstedt, Sibylle Neuhoff, Paavo Hon...> ;Hepatology Communications. 2024 Mar 1
• Hepatic NLRP3-Derived Hsp70 Binding to TLR4 Mediates MASLD to MASH Progression upon Inhibition of PP2A by Harmful Algal Bloom Toxin Microcystin, a Second Hit.
  Subhajit Roy, Punnag Saha, Dipro Bose, Ayushi Trivedi, Madhura More, Shuo Xiao, Anna Mae Diehl, Saurabh Chatterjee> ;International Journal of Molecular Sciences. 2023 Nov 15
• Serum Metabolites Are Associated With HFpEF in Biopsy-Proven Nonalcoholic Fatty Liver Disease.
  Kara Wegermann, Marat Fudim, Ricardo Henao, Catherine F Howe, Robert McGarrah, Cynthia Guy, Manal F Abdelmalek, Anna Mae Diehl, Cynthia A Moylan> ;Journal of the American Heart Association. 2023 Jul 18
• 1 citations
  Longer Breastfeeding Duration Is Associated With Decreased Risk of Hepatic Fibrosis Among Young Women With Nonalcoholic Fatty Liver Disease.
  Georgia Sofia Karachaliou, Ayako Suzuki, Vaishali A Patel, Lori A Bastian, Anna Mae Diehl, Manal F Abdelmalek> ;Clinical Gastroenterology and Hepatology. 2024 Feb 1
• 6 citations
  Antagonizing the irreversible thrombomodulin-initiated proteolytic signaling alleviates age-related liver fibrosis via senescent cell killing.
  Christopher C Pan, Raquel Maeso-Díaz, Tylor R Lewis, Kun Xiang, Lianmei Tan, Yaosi Liang, Liuyang Wang, Fengrui Yang, Tao Yin, Calvin Wang, Kuo Du, De Huang, Seh Hoon ...> ;Cell Research. 2023 Jul 1
• 24 citations
  Fibrosis Progression Rate in Biopsy-Proven Nonalcoholic Fatty Liver Disease Among People With Diabetes Versus People Without Diabetes: A Multicenter Study.
  Daniel Q Huang, Laura A Wilson, Cynthia Behling, David E Kleiner, Kris V Kowdley, Srinivasan Dasarathy, Maral Amangurbanova, Norah A Terrault, Anna Mae Diehl, Naga Cha...> ;Gastroenterology. 2023 Aug 1
• 3 citations
  Rescue of glutaric aciduria type I in mice by liver-directed therapies.
  Mercedes Barzi, Collin G Johnson, Tong Chen, Ramona M Rodriguiz, Madeline Hemmingsen, Trevor J Gonzalez, Alan Rosales, James Beasley, Cheryl K Peck, Yunhan Ma, Ashlee ...> ;Science Translational Medicine. 2023 Apr 19
• 2 citations
  Targeting senescent hepatocytes using the thrombomodulin-PAR1 inhibitor vorapaxar ameliorates NAFLD progression.
  Raquel Maeso-Díaz, Kuo Du, Christopher Pan, Cynthia D Guy, Seh Hoon Oh, Tianyi Chen, Liuyang Wang, Dennis C Ko, Linda Tang, Rajesh K Dutta, Ji Hye Jun, Ayako Suzuki, M...> ;Hepatology. 2023 Oct 1
• 4 citations
  Hepatocyte Smoothened Activity Controls Susceptibility to Insulin Resistance and Nonalcoholic Fatty Liver Disease.
  Tianyi Chen, George Dalton, Seh-Hoon Oh, Raquel Maeso-Diaz, Kuo Du, Rachel A Meyers, Cynthia Guy, Manal F Abdelmalek, Ricardo Henao, Paolo Guarnieri, Steven S Pullen, ...> ;Cellular and Molecular Gastroenterology and Hepatology. 2023 Jan 1
• 9 citations
  Defining the serum proteomic signature of hepatic steatosis, inflammation, ballooning and fibrosis in non-alcoholic fatty liver disease.
  Arun J Sanyal, Stephen A Williams, Joel E Lavine, Brent A Neuschwander-Tetri, Leigh Alexander, Rachel Ostroff, Hannah Biegel, Kris V Kowdley, Naga Chalasani, Srinivasa...> ;Journal of Hepatology. 2023 Apr 1
• 7 citations
  Deep learning-based quantification of NAFLD/NASH progression in human liver biopsies.
  Fabian Heinemann, Peter Gross, Svetlana Zeveleva, Hu Sheng Qian, Jon Hill, Anne Höfer, Danny Jonigk, Anna Mae Diehl, Manal Abdelmalek, Martin C Lenter, Steven S Pullen...> ;Scientific Reports. 2022 Nov 10
• 3 citations
  Alterations in DNA methylation associate with fatty liver and metabolic abnormalities in a multi-ethnic cohort of pre-teenage children.
  Cynthia A Moylan, Alisha M Mavis, Dereje Jima, Rachel Maguire, Mustafa Bashir, Jeongeun Hyun, Melanie N Cabezas, Alice Parish, Donna Niedzwiecki, Anna Mae Diehl, Susan...> ;Epigenetics. 2022 Nov 1
• 4 citations
  Dynamics of hepatocyte-cholangiocyte cell-fate decisions during liver development and regeneration.
  Sarthak Sahoo, Ashutosh Mishra, Anna Mae Diehl, Mohit Kumar Jolly> ;Iscience. 2022 Sep 16
• 22 citations
  Spermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression.
  Jin Zhou, Jeremy Pang, Madhulika Tripathi, Jia Pei Ho, Anissa Anindya Widjaja, Shamini Guna Shekeran, Stuart Alexander Cook, Ayako Suzuki, Anna Mae Diehl, Enrico Petre...> ;Nature Communications. 2022 Sep 3
• 1 citations
  Determinants of the severity of fatty liver diseases: Need all the pieces to solve the puzzle.
  Hélène Pailhoriès, Jerome Boursier, Anna Mae Diehl> ;Hepatology. 2022 Apr 1
• 7 citations
  Aging reduces liver resiliency by dysregulating Hedgehog signaling.
  Raquel Maeso-Díaz, George D Dalton, Sehhoon Oh, Kuo Du, Linda Tang, Tianyi Chen, Rajesh K Dutta, Jessica H Hartman, Joel N Meyer, Anna Mae Diehl> ;Aging Cell. 2022 Feb 1
• 5 citations
  Zac1 and the Imprinted Gene Network program juvenile NAFLD in response to maternal metabolic syndrome.
  Marine Baptissart, Christine M Bradish, Brie S Jones, Evan Walsh, Jesse Tehrani, Vicmarie Marrero-Colon, Sanya Mehta, Dereje D Jima, Seh Hoon Oh, Anna Mae Diehl, Tiffa...> ;Hepatology. 2022 Oct 1
• 11 citations
  Probing gut-brain links in Alzheimer's disease with rifaximin.
  Paul V Suhocki, James S Ronald, Anna Mae E Diehl, David M Murdoch, P Murali Doraiswamy> ;Alzheimer's & Dementia. 2022 Jan 1
• 29 citations
  Nonalcoholic Fatty Liver Disease and Risk of Heart Failure Among Medicare Beneficiaries.
  Marat Fudim, Lin Zhong, Kershaw V. Patel, Rohan Khera, Manal F. Abdelmalek, Anna Mae Diehl, Robert W. McGarrah, Jeroen Molinger, Cynthia A. Moylan, Vishal N. Rao, Kara...> ;Journal of the American Heart Association. 2021 Nov 16
• 37 citations
  Relationship of Nonalcoholic Fatty Liver Disease and Heart Failure With Preserved Ejection Fraction
  Husam M. Salah, Ambarish Pandey, A. Soloveva, Manal F. Abdelmalek, Anna Mae Diehl, Cynthia A. Moylan, Kara Wegermann, Vishal N. Rao, Adrian F. Hernandez, Ryan J. Tedfo...> ;JACC. Basic to Translational Science. 2021 Nov 1
• 12 citations
  Perceptions of Exercise and Its Challenges in Patients With Nonalcoholic Fatty Liver Disease: A Survey-Based Study.
  Oliver Glass, Daniel Liu, Elizabeth Bechard, Cynthia D. Guy, Jane F. Pendergast, Anna Mae Diehl, Manal F. Abdelmalek> ;Hepatology Communications. 2021 Oct 26
• 297 citations
  Prospective Study of Outcomes in Adults with Nonalcoholic Fatty Liver Disease.
  Arun J. Sanyal, Mark L. Van Natta, Jeanne M. Clark, Brent A. Neuschwander-Tetri, Anna Mae Diehl, Srinivasan Dasarathy, Rohit Loomba, Naga Chalasani, Kris V. Kowdley, B...> ;The New England Journal of Medicine. 2021 Oct 21
• 3 citations
  Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice.
  George D. Dalton, Seh-Hoon Oh, Linda Tang, Stephanie Zhang, Amanda L. Brown, Venkateshwari Varadharajan, Camelia Baleanu-Gogonea, Valentin Gogonea, Preeti Pathak, J. M...> ;Iscience. 2021 Sep 24
• Inflammation Writes the Fibrogenic Code.
  Matthew B Friedersdorf, Anna Mae Diehl> ;Cellular and Molecular Gastroenterology and Hepatology. 2021 Jul 2
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Journal Articles

• Reply to HEP-12-0274R1  
  Diehl AM, Hepatology, 3/20/2012
• Correlation of Vitamin E, Uric Acid, and Diet Composition with Histologic Features of Pediatric NAFLD  
  Vos MB, Colvin R, Belt P, Molleston JP, Murray KF, Rosenthal P, Schwimmer JB, Tonascia J, Unalp A, Lavine JE, NASH CRN Research Group, Pediatr Gastroenterol Nutr, 1/1/2012
• Effect of Vitamin E or Metformin for Treatment of Nonalcoholic Fatty Liver Disease in Children and Adolescents: the TONIC Randomized Controlled Trial  
  Lavine JE, Schwimmer JB, Van Natta ML, Mosseston JP et al Nonalcoholic Steatohepatitis Clinical Research Networ, JAMA, 4/27/2011
• Nonalcoholic Fatty Liver Disease (NAFLD) Activity Score and the Histopathologic Diagnosis in NAFLD: Distinct Clinicopathologic Meanings  
  Brunt EM, Kleiner DE, Wilson LA, Belt P, Neuschwander-Tetri BA, NASH Clinical Research Network (CRN), Hepatology, 3/1/2011
• Non-alcoholic steatohepatitis pathogenesis: Role of repair in regulating disease progression  
  Jung Y, Diehl AM, Dig Dis, 1/1/2010
• Epithelial-mesenchymal tranisitions and hepatocarcinogenesis  
  Jou J, Diehl AM, J Clin Invest, 1/1/2010
• For the Nonalcoholic Steatohepatitis Clinical Research Network Increased fructose consumption is associated with fibrosis severity in patients with nonalcholoic fatty...  
  Abdelmalek MF, Suzuki A, Guy C, Unalp-Arida A, Colvin R, Johnson RJ, Diehl AM, Hepatology, 1/1/2009
• The adventures of sonic hedgehog in development and repair II Sonic hedgehog and live development, inflammation and cancer  
  Omenetti A, Diehl AM, Physiol Gastrointest Liver Physiol, 3/1/2008
• What does a specialized center for transplantation and heptobiliary disease have on post-graduate resident training of gastroenterologists and surgeons?  
  Tuttle-Newhall JE, Diehl AM, J Hepatol, 1/1/2006
• Abnormal exhaled ethane concentrations in scleroderma  
  Cope KA, Solga SF, Hummers LK, Wigley FM, Diehl AM, Risby TH, Biomarkers, 1/1/2006
• Breath biomarkers and non-alcoholic fatty liver disease: preliminary observations  
  Solga SF, Alkhuraishe A, Cope K, Tabesh A, Clark JM, Torbenson M, Schwartz P, Magnuson T, Diehl AM, Risby TH, Biomarkers, 1/1/2006
• Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis  
  Sicklick JK, Li YX, Jayaraman A, Kannangai R, Qi Y, Vivekanandan P, Ludlow JW, Owzar K, Chen W, Torbenson MS, Diehl AM, Carcinogenesis, 1/1/2006
• Recent Events in Alcoholic Liver Disease V Effects of ethanol on liver regeneration  
  Diehl AM, Am J Physiol Gastrointest Liver, 1/1/2005
• Cytokines and the Pathogenesis of NASH  
  Diehl AM. Li Z, Lin H, Yang S, Gut: Recent Advances in Clinical Practice, 1/1/2005
• Arterial Homeostasis, inflammation, and erythropoietic growth factors  
  Goldschmidt-Clermont PJ, Diehl AM, Rev Cardiovasc Med, 1/1/2005
• Should nonalcoholic fatty liver disease be treated differently in elderly patients?  
  Suzuki A, Diehl AM, Nat Clin Pract Gastroenterol Hepatol, 1/1/2005
• Cytokines and the pathogenesis of non-alcoholic steatohepatitis  
  Diehl AM, Li ZP, Lin HZ, Yang SQ, Gut, 1/1/2005
• Hepatic 31P magnetic resonance spectroscopy: a hepatologist's user guide  
  Solga SF, Horska A, Clark JM, Diehl AM, Liver Int, 1/1/2005
• Insulin resistance and steatosis in hepatitis C virus infection  
  Zekry, A, McHutchison JG, Diehl AM, Gut, 1/1/2005
• Gut flora-based therapy in liver disease?  
  Solga SF, Diehl AM, Hepatology, 1/1/2004
• Fatty liver, hypertension, and the metabolic syndrome  
  Diehl, AM, Gut, 1/1/2004
• Hepatic fibrogenesis requires sympathetic neurotransmitters  
  Oben JA, Roskams T, Yang S, Lin H, Sinelli N, Torbenson M, Smedh U, Moran TH, Li Z, Huang J, Thomas SA, Diehl AM, Gut, 1/1/2004
• Hematopoietic stem cells convert into liver cells within days without fusion  
  Jang YY, Collector MI, Baylin SB, Diehl AM, Sharkis SJ, Nat Cell Biol, 1/1/2004
• Metformin in the treatment of non-alcoholic steatohepatitis: a pilot open laboratory trial  
  Nair S, Diehl AM, Wiseman M, Farr GH Jr, Perrillo RP, Aliment Pharmacol Ther, 1/1/2004
• Non-alcoholic fatty liver disease: lumen-liver interactions and possible role for probiotics  
  Solga SF, Diehl AM, J Hepatol, 1/1/2003
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