AnnetteFOkaiMD

Neurology • Plano, TX

Neuroimmunology/Multiple Sclerosis

Director, Neuroimmunology and Multiple Sclerosis Research North Texas Institute of Neurology and Headache

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Office
6201 Dallas Parkway
ste 100
Plano, TX 75024
Phone+1 972-403-4148
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Summary

Dr. Annette Okai is a neurologist fellowship trained in Multiple Sclerosis in Dallas, TX. She received her medical degree from Drexel University College of Medicine/Hahnemann University and has been in practice 13 years. She is experienced in multiple sclerosis, neurology, and clinical trials. She has more than 10 publications and over 50 citings.

Education & Training

Sidney Kimmel Medical College at Thomas Jefferson University/TJUHFellowship, Neuroimmunology & Multiple Sclerosis, 2006 - 2008
Sidney Kimmel Medical College at Thomas Jefferson University/TJUHResidency, Neurology, 2003 - 2006
Pennsylvania Hospital of the University of Pennsylvania Health SystemInternship, Internal Medicine, 2002 - 2003
Drexel University College of MedicineClass of 2002

Certifications & Licensure

DE State Medical License 2007 - 2025
PA State Medical License 2002 - 2024
TX State Medical License 2008 - 2024
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

Most Compassionate Doctor American Registry

Clinical Trials

Study to Assess the Efficacy and Safety of Ublituximab in Participants With Relapsing Forms of Multiple Sclerosis (RMS) ( ULTIMATE 1 ) Start of enrollment: 2017 Sep 19
Completed
Phase 3
Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial Start of enrollment: 2018 May 02
Recruiting
Not Applicable
An Extension Study of Ublituximab in Participants With Relapsing Multiple Sclerosis Start of enrollment: 2019 Nov 18
Active, not recruiting
Phase 3
Cladribine Tablets After Treatment With Natalizumab (CLADRINA) Start of enrollment: 2020 Feb 19
Active, not recruiting
Phase 4
Prospective Study to Assess Disease Activity and Biomarkers in Minority Participants With Relapsing Multiple Sclerosis (RMS) After Initiation and During Treatment With Ocrelizumab. Start of enrollment: 2020 Jul 30
Active, not recruiting
Phase 4
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Publications & Presentations

PubMed

Disparities by Race in Pregnancy Care and Clinical Outcomes in Women With Multiple Sclerosis: A Diverse Multicenter Cohort
Anne Marie Radzik, Lilyana Amezcua, Annika Anderson, Serena Gilmore, Sophie Ahmad, Rachel Brandstadter, Michelle T Fabian, Edith L Graham, Sophia Hodgkinson, Lindsay H...> ;Neurology. 2024 Feb 27
Cladribine tablets after treatment with natalizumab (CLADRINA) - rationale and design.
Rehana Z Hussain, Mariam Madinawala, Julie Korich, Lori A Lebson, Amber Salter, Navid Manouchehri, Peter V Sguigna, Annette Okai, Kyle M Blackburn, Lauren Tardo, Jeffr...> ;Therapeutic Advances in Neurological Disorders. 2024 Jan 1
Cognitive Symptom Awareness Among Patients With Multiple Sclerosis Using a Mobile Application.
Miller, D., Dena Miller, Annette Okai, Kathleen Scott, Staci S Reynolds> ;Rehabilitation Nursing. 2023 Dec 11
1 citations
Real-World Safety and Effectiveness After 5 Years of Dimethyl Fumarate Treatment in Black and Hispanic Patients with Multiple Sclerosis in ESTEEM.
Mitzi J Williams, Lilyana Amezcua, Angel Chinea, Stanley Cohan, Annette Okai, Darin T Okuda, Wendy Vargas, Nick Belviso, Ivan Božin, Xiaotong Jiang, James B Lewin, Jen...> ;Neurology and Therapy. 2023 Oct 1
1 citations
Demographics and baseline disease characteristics of Black and Hispanic patients with multiple sclerosis in the open-label, single-arm, multicenter, phase IV CHIMES tr...
Mitzi J Williams, Annette F Okai, Anne H Cross, Nancy L Monson, Timothy Vartanian, Ben W Thrower, Anthony T Reder, Jeffrey B English, Gregory F Wu, Evanthia Bernitsas,...> ;Multiple Sclerosis and Related Disorders. 2023 Aug 1
27 citations
Dimethyl Fumarate Delays Multiple Sclerosis in Radiologically Isolated Syndrome.
Darin T Okuda, Orhun Kantarci, Christine Lebrun-Frénay, Maria Pia Sormani, Christina J Azevedo, Francesca Bovis, Le H Hua, Lilyana Amezcua, Ellen M Mowry, Christophe H...> ;Annals of Neurology. 2023 Mar 1
6 citations
Advancing Care and Outcomes for African American Patients With Multiple Sclerosis.
Annette F Okai, Annette M Howard, Mitzi J Williams, Chiayi Chen, Tamela L Stuchiner, Elizabeth Baraban, Grace Jeong, Stanley L Cohan, Brink, J.> ;Neurology. 2022 Jun 14
The sequential natalizumab - alemtuzumab therapy in patients with relapsing forms of multiple sclerosis (SUPPRESS) trial - Part I: Rationale and objectives.
Rehana Z Hussain, Peter V Sguigna, Annette Okai, Crystal Wright, Mariam Madinawala, Ann D Bass, Gary R Cutter, Navid Manouchehri, Olaf Stuve> ;Journal of Central Nervous System Disease. 2022 Jan 1
19 citations
Effects of Menopause in Women With Multiple Sclerosis: An Evidence-Based Review
Riley Bove, Annette Okai, Maria K. Houtchens, Birte Elias-Hamp, Alessandra Lugaresi, Kerstin Hellwig, Eva Havrdova> ;Frontiers in Neurology. 2021 Jan 1
6 citations
Identifying disability level in multiple sclerosis patients in a U.S.-based health plan claims database
Regina Berkovich, Edward Fox, Annette Okai, Yao Ding, Magdaliz Gorritz, Lauren Bartolome, Rolin L Wade, Wendy Su, Kristen Johnson, Patricia A. Russo> ;Journal of Medical Economics. 2021 Jan 1
7 citations
Efficacy and Safety of Alemtuzumab in Patients of African Descent with Relapsing-Remitting Multiple Sclerosis: 8-Year Follow-up of CARE-MS I and II (TOPAZ Study)
Annette Okai, Lilyana Amezcua, Regina Berkovich, Angel Chinea, Keith R. Edwards, Brian Steingo, Aljoeson Walker, Alan Jacobs, Nadia Daizadeh, Mitzi J. Williams> ;Neurology and Therapy. 2019 Oct 25
4 citations
Real-World Observational Evaluation of Hair Thinning in Patients with Multiple Sclerosis Receiving Teriflunomide: Is It an Issue in Clinical Practice?
Lori Hendin Travis, Annette Okai, Steve Cavalier, Darren Stam, Lisa Farnett, Keith R. Edwards> ;Neurology and Therapy. 2018 Aug 6
Ofatumumab versus Teriflunomide in Multiple Sclerosis.
Hauser SL, Bar-Or A, Cohen JA, Comi G, Correale J, Coyle PK, Cross AH, de Seze J, Leppert D, Montalban X, Selmaj K, Wiendl H, Kerloeguen C, Willi R, Li B, Kakarieka A,...> ;The New England journal of medicine.
The effect of tonsillectomy on John Cunningham virus serological status in multiple sclerosis patients: A retrospective case–control study:
Mirla Avila, Annette Okai, Smathorn Thakolwiboon, Collin J. O’Bryan, Murali Mohan Reddy Gopireddy, Sasikanth Gorantla> ;Multiple Sclerosis. 2021 Jul 1
10 citations
Real-World Safety and Effectiveness of Dimethyl Fumarate in Hispanic or Latino Patients with Multiple Sclerosis: 3-Year Results from ESTEEM.
Angel Chinea, Lilyana Amezcua, Wendy Vargas, Annette Okai, Mitzi J. Williams, Ray Su, Becky Parks, Jason P. Mendoza, James B. Lewin, Cynthia C. Jones> ;Neurology and Therapy. 2020 May 29
19 citations
Real-World Safety and Effectiveness of Dimethyl Fumarate in Black or African American Patients with Multiple Sclerosis: 3-Year Results from ESTEEM.
Mitzi J. Williams, Lilyana Amezcua, Annette Okai, Darin T. Okuda, Stanley Cohan, Ray Su, Becky Parks, Jason P. Mendoza, James B. Lewin, Cynthia C. Jones> ;Neurology and Therapy. 2020 May 29
1 citations
Heat exposure and bicycling trigger recurrent aseptic meningitis: a case report
Olaf Stüve, Ellen Marder, Annette Okai, Mark Stettner, Bernd C. Kieseier> ;BMC Neurology. 2014 Dec 31
22 citations
Toward a practical protocol for human optic nerve DTI with EPI geometric distortion correction.
Udomchai Techavipoo, Annette F. Okai, John Lackey, Jianrong Shi, Michael A. Dresner, Thomas Leist, Song Lai> ;Journal of Magnetic Resonance Imaging. 2009 Oct 1
20 citations
Progressive necrotizing myelopathy: part of the spectrum of neuromyelitis optica?
Annette F. Okai, Srikanth Muppidi, Ritu Bagla, Thomas Leist> ;Neurological Research. 2006 Apr 1
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Press Mentions

Virtual AAN Meeting Features Reports on MS Symptoms, COVID-19, Health Disparities, Emerging Therapies, and MoreApril 27th, 2021
MSAA Events Focus on Mind-Body Connection to Mark MS Awareness MonthMarch 11th, 2020
MS Progression Focus of MSAA Events, ‘Ask Experts’ Sessions for Awareness MonthAugust 30th, 2018
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