AnujGaggarMD

PubMed

• Safety, pharmacodynamics, and antiviral activity of selgantolimod in viremic patients with chronic hepatitis B virus infection.
  Janssen, H., Lim, Y., Kim, H., Sowah, L., Tseng, C., Coffin, C., Elkhashab, M., Ahn, S., Nguyen, A., Chen, D., Wallin, J., Fletcher, S., McDonald, C., Yang, J., Gaggar...> ;JHEP Reports. 2024 Feb 1
• 3 citations
  Intrahepatic quantification of HBV antigens in chronic hepatitis B reveals heterogeneity and treatment-mediated reductions in HBV core-positive cells.
  Abhishek Aggarwal, Pamela M Odorizzi, Jens Brodbeck, Nicholas van Buuren, Christina Moon, Silvia Chang, MaryVic Adona, Silpa Suthram, Vithika Suri, Torsten Trowe, Scot...> ;JHEP Reports. 2023 Apr 1
• 8 citations
  Safety and efficacy of the oral TLR8 agonist selgantolimod in individuals with chronic hepatitis B under viral suppression.
  Gane, E., Dunbar, P., Brooks, A., Zhang, F., Chen, D., Wallin, J., van Buuren, N., Arora, P., Fletcher, S., Tan, S., Yang, J., Tang, L., Gaggar, A., Kottilil, S.> ;Journal of Hepatology. 2023 Mar 1
• 6 citations
  Phenotypic CD8 T cell profiling in chronic hepatitis B to predict HBV-specific CD8 T cell susceptibility to functional restoration in vitro.
  Marzia Rossi, Andrea Vecchi, Camilla Tiezzi, Valeria Barili, Paola Fisicaro, Amalia Penna, Ilaria Montali, Stephane Daffis, Simon P Fletcher, Anuj Gaggar, Jonathan Med...> ;Gut. 2023 Nov 1
• 25 citations
  COVID-19 bacteremic co-infection is a major risk factor for mortality, ICU admission, and mechanical ventilation.
  Michael John Patton, Carlos J Orihuela, Kevin S Harrod, Mohammad A N Bhuiyan, Paari Dominic, Christopher G Kevil, Daniel Fort, Vincent X Liu, Maha Farhat, Jonathan L K...> ;Critical Care. 2023 Jan 23
• 21 citations
  Longitudinal liver sampling in patients with chronic hepatitis B starting antiviral therapy reveals hepatotoxic CD8+ T cells.
  Shirin Nkongolo, Deeqa Mahamed, Adrian Kuipery, Juan D Sanchez Vasquez, Samuel C Kim, Aman Mehrotra, Anjali Patel, Christine Hu, Ian McGilvray, Jordan J Feld, Scott Fu...> ;The Journal of Clinical Investigation. 2023 Jan 3
• 19 citations
  Nomenclature of HBV core protein-targeting antivirals.
  Wang, S. H., Fabien Zoulim, Adam Zlotnick, Stephanie Buchholz, Eric Donaldson, John Fry, Anuj Gaggar, Jianming Hu, Michael Kann, Oliver Lenz, Kai Lin, Nagraj Mani, Mic...> ;Nature Reviews. Gastroenterology & Hepatology. 2022 Dec 1
• 1 citations
  Hepatitis B virus haplotype number at baseline is a predictive marker of functional cure during antiviral therapy for patients with genotypes A and D HBeAg-positive ch...
  Josef Wagner, Lilly Yuen, Margaret Littlejohn, Vitina Sozzi, Kathy Jackson, Ross Martin, Thomas Aeschbacher, Vithika Suri, Susanna K Tan, Becket Feierbach, Anuj Gaggar...> ;Alimentary Pharmacology & Therapeutics. 2023 Mar 1
• 4 citations
  Secreted hepatitis B virus splice variants differ by HBV genotype and across phases of chronic hepatitis B infection.
  Olivia Maslac, Josef Wagner, Vitina Sozzi, Hugh Mason, Jenny Svarovskaia, Susanna Tan, Anuj Gaggar, Stephen Locarnini, Lilly Yuen, Margaret Littlejohn, Peter A Revill> ;Journal of Viral Hepatitis. 2022 Aug 1
• 6 citations
  Ledipasvir-sofosbuvir in Adolescents With Chronic Hepatitis C and Hematological Malignancies Undergoing Chemotherapy.
  Manal Hamdy El-Sayed, Fatma S Elsayed Ebeid, Abdel-Rahman Zekri, Benedetta Massetto, Kathryn Kersey, Fangqiu Zhang, Anuj Gaggar, Walaa Elsayed, Alaa El-Haddad> ;Journal of Pediatric Gastroenterology and Nutrition. 2022 May 1
• 6 citations
  Sofosbuvir and risk of estimated glomerular filtration rate decline or end-stage renal disease in patients with renal impairment.
  Mark Sulkowski, Laura E Telep, Massimo Colombo, Francois Durand, K Rajender Reddy, Eric Lawitz, Marc Bourlière, Nelson Cheinquer, Stacey Scherbakovsky, Liyun Ni, Linds...> ;Alimentary Pharmacology & Therapeutics. 2022 May 1
• 27 citations
  Inhibition of Viral Replication Reduces Transcriptionally Active Distinct Hepatitis B Virus Integrations With Implications on Host Gene Dysregulation.
  Yao-Chun Hsu, Vithika Suri, Mindie H Nguyen, Yen-Tsung Huang, Chi-Yi Chen, I-Wei Chang, Cheng-Hao Tseng, Chun-Ying Wu, Jaw-Town Lin, David Z Pan, Anuj Gaggar, Ondrej P...> ;Gastroenterology. 2022 Apr 1
• 9 citations
  Risk of hepatocellular carcinoma in treatment-naïve chronic hepatitis B patients receiving tenofovir disoproxil fumarate versus entecavir in the United States.
  W Ray Kim, Laura E Telep, Belinda Jump, Mei Lu, Heribert Ramroth, John Flaherty, Anuj Gaggar, Anand P Chokkalingam, Stuart C Gordon> ;Alimentary Pharmacology & Therapeutics. 2022 Apr 1
• 16 citations
  Targeted long-read sequencing reveals clonally expanded HBV-associated chromosomal translocations in patients with chronic hepatitis B.
  Nicholas van Buuren, Ricardo Ramirez, Cameron Soulette, Vithika Suri, Dong Han, Lindsey May, Scott Turner, P C Parvangada, Ross Martin, Henry L Y Chan, Patrick Marcell...> ;JHEP Reports. 2022 Apr 1
• 3 citations
  Ledipasvir/Sofosbuvir for Patients Coinfected With Chronic Hepatitis C and Hepatitis B in Taiwan: Follow-up at 108 Weeks Posttreatment.
  Chun Jen Liu, I Shyan Sheen, Chi Yi Chen, Wan Long Chuang, Horng Yuan Wang, Kuo Chih Tseng, Ting Tsung Chang, Jenny Yang, Benedetta Massetto, Vithika Suri, Gregory Cam...> ;Clinical Infectious Diseases. 2022 Aug 31
• 15 citations
  Characterization of the liver immune microenvironment in liver biopsies from patients with chronic HBV infection
  Nicholas van Buuren, Ricardo Ramirez, Scott Turner, Diana Chen, Vithika Suri, Abhishek Aggarwal, Christina Moon, Samuel Kim, Dmytro Kornyeyev, Nam Bui, Neeru Bhardwaj,...> ;JHEP Reports. 2021 Oct 23
• 26 citations
  Safety, pharmacokinetics, and pharmacodynamics of the oral TLR8 agonist selgantolimod in chronic hepatitis B
  Edward Gane, Hyung Joon Kim, Kumar Visvanathan, Yoon Jun Kim, Anh Hoa Nguyen, Jeffrey J. Wallin, Diana Y. Chen, Circe McDonald, Priyanka Arora, Susanna K. Tan, Anuj Ga...> ;Hepatology. 2021 Oct 1
• 6 citations
  Ledipasvir/Sofosbuvir for 8, 12, or 24 Weeks in Hepatitis C Patients Undergoing Dialysis for End-Stage Renal Disease.
  Wan-Long Chuang, Tsung Hui Hu, Peter Buggisch, Christophe Moreno, Wei Wen Su, Luigi Biancone, Marianne Camargo, Robert H. Hyland, Sophia Lu, Brian J. Kirby, Hadas Dvor...> ;The American Journal of Gastroenterology. 2021 Sep 1
• 13 citations
  DNA Methylation and Immune Cell Markers Demonstrate Evidence of Accelerated Aging in Patients with Chronic Hepatitis B Virus or Hepatitis C Virus, with or without Huma...
  Yevgeniy Gindin, Anuj Gaggar, Anna S. Lok, Harry L.A. Janssen, Carlo Ferrari, G. Mani Subramanian, Zhaoshi Jiang, Henry Masur, Benjamin Emmanuel, Bhawna Poonia, Shyam ...> ;Clinical Infectious Diseases. 2021 Jul 1
• Hepatitis B Virus Genome Diversity in Adolescents: Tenofovir Disoproxil Fumarate Treatment Effect and HBeAg Seroconversion
  Christophe Combet, Neeru Bhardwaj, Charlotte Hedskog, Ondrej Podlaha, Anuj Gaggar, Karen F. Murray, Hongmei Mo, Evguenia S. Svarovskaia, Fabien Zoulim> ;Journal of Viral Hepatitis. 2021 May 18
• 5 citations
  Antiviral kinetics of tenofovir alafenamide and tenofovir disoproxil fumarate over 24 weeks in women of childbearing potential with chronic HBV.
  Calvin Q. Pan, Ting-Tsung Chang, Si Hyun Bae, Maurizia Rossana Brunetto, Wai-Kay Seto, Carla S. Coffin, Susanna K. Tan, Shuyuan Mo, John F. Flaherty, Anuj Gaggar, Mind...> ;Plos One. 2021 May 13
• 8 citations
  Analysis of Hepatitis B Virus Haplotype Diversity Detects Striking Sequence Conservation Across Genotypes and Chronic Disease Phase
  Josef Wagner, Lilly Yuen, Margaret Littlejohn, Vitina Sozzi, Kathy Jackson, Vithika Suri, Susanna K. Tan, Becket Feierbach, Anuj Gaggar, Patrick Marcellin, Maria Buti ...> ;Hepatology. 2021 May 1
• 17 citations
  3-year Treatment of Tenofovir Alafenamide vs. Tenofovir Disoproxil Fumarate for Chronic HBV Infection in China.
  Jinlin Hou, Qin Ning, Zhongping Duan, You Chen, Qing Xie, Fu-Sheng Wang, Lunli Zhang, Shanming Wu, Hong Tang, Jun Li, Feng Lin, Yongfeng Yang, Guozhong Gong, John F. F...> ;Journal of Clinical and Translational Hepatology. 2021 Apr 28
• 8 citations
  Long-Term Patient Centered Outcomes in Cirrhotic Patients with Chronic Hepatitis C After Achieving Sustained Virologic Response.
  Zobair M. Younossi, Andrei Racila, Andrew J. Muir, Marc Bourlière, Alessandra Mangia, Rafael Esteban, Stefan Zeuzem, Massimo Colombo, Michael Manns, George V. Papatheo...> ;Clinical Gastroenterology and Hepatology. 2021 Jan 22
• PNPLA3 polymorphisms are associated with raised alanine aminotransferase levels in hepatitis C virus genotype 3.
  Tanvi Agrawal, Anuj Gaggar, Mani Subramanian, Shyam Kottilil, Abhijit Choudhary, Padaki Nagaraja Rao, Sameer Shah, Nirupma Trehanpati> ;Arab Journal of Gastroenterology. 2020 Dec 1
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Journal Articles

• Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients with Moderate COVID-19  
  Robert L Gottlieb, Gerard J Criner, Onyema Ogbuagu, Kathleen M Mullane, Anuj Gaggar, Diana M Brainard, Gregory Huhn, JAMA