AriBenjaminMolofskyMD

Pathology • San Francisco, CA

Hematopathology, Anatomic Pathology, Clinical Pathology

Instructor, Laboratory Medicine, UCSF School of Medicine

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Office
505 Parnassus Ave
M524, Box 100
San Francisco, CA 94143
Phone+1 415-443-0048
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Education & Training

University of California (San Francisco)Residency, Pathology-Anatomic and Clinical, 2007 - 2011
University of California (San Francisco)Fellowship, Hematopathology, 2009 - 2010
University of Michigan Medical SchoolClass of 2007

Certifications & Licensure

CA State Medical License 2009 - 2025
American Board of Pathology Pathology - Clinical
American Board of Pathology Hematopathology

Publications & Presentations

PubMed

9 citations
The ins and outs of innate and adaptive type 2 immunity.
Ari B Molofsky, Richard M Locksley> ;Immunity. 2023 Apr 11
32 citations
Early-life inflammation primes a T helper 2 cell–fibroblast niche in skin
Ian C. Boothby, Maxime J. Kinet, Devi P. Boda, Elaine Y. Kwan, Sean Clancy, Jarish N. Cohen, Ireneusz Habrylo, Margaret M. Lowe, Mariela L. Pauli, Ashley E. Yates, Jam...> ;Nature. 2021 Oct 27
27 citations
Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice.
Julia Kuhn, Ilia D. Vainchtein, Joao M. Braz, Katherine A. Hamel, Mollie Bernstein, Veronica B. Craik, Madelene W. Dahlgren, Jorge F. Ortiz-Carpena, Ari B. Molofsky, A...> ;Elife. 2021 Oct 15
12 citations
Perivascular stromal cells: Directors of tissue immune niches
Julia Sbierski-Kind, Nicholas M. Mroz, Ari B. Molofsky> ;Immunological Reviews. 2021 Jun 1
48 citations
Gli1 + mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung.
Monica Cassandras, Chaoqun Wang, Jaymin J. Kathiriya, Tatsuya Tsukui, Peri Matatia, Michael A. Matthay, Paul J. Wolters, Ari B. Molofsky, Dean Sheppard, H.A. Chapman, ...> ;Nature Cell Biology. 2020 Oct 12
277 citations
Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity.
Phi T. Nguyen, Leah C. Dorman, Simon Pan, Ilia D. Vainchtein, Rafael T. Han, Hiromi Nakao-Inoue, Sunrae E. Taloma, Jerika J. Barron, Ari B. Molofsky, Mazen A. Kheirbek...> ;Cell. 2020 Jul 23
3 citations
Immune outposts in the adventitia: One foot in sea and one on shore.
Kelly M. Cautivo, Catherine A. Steer, Ari B. Molofsky> ;Current Opinion in Immunology. 2020 Apr 24
4 citations
Tissue immunity broadcasts near and far.
Ari B. Molofsky, Richard M. Locksley> ;Nature Reviews. Immunology. 2020 Feb 1
3 citations
Universal Principled Review: A Community-Driven Method to Improve Peer Review
Matthew F. Krummel, Catherine A. Blish, Michael S. Kuhns, Ken Cadwell, Andrew Oberst, Ananda W. Goldrath, K. Mark Ansel, Hongbo Chi, Ryan M. O'Connell, E. John Wherry,...> ;Cell. 2019 Dec 12
24 citations
Adventitial Cuffs: Regional Hubs for Tissue Immunity.
Madelene W. Dahlgren, Ari B. Molofsky> ;Trends in Immunology. 2019 Oct 1
21 citations
Nur77 Links Chronic Antigen Stimulation to B Cell Tolerance by Restricting the Survival of Self-Reactive B Cells in the Periphery.
Corey Tan, James L. Mueller, Mark Noviski, John Huizar, Denise Lau, Alexandra Dubinin, Ari B. Molofsky, Patrick C. Wilson, Julie Zikherman> ;Journal of Immunology. 2019 May 15
22 citations
Group 2 Innate Lymphoid Cells Are Redundant in Experimental Renal Ischemia-Reperfusion Injury.
Guy J. M. Cameron, Kelly M. Cautivo, Svenja Loering, Simon H Jiang, Aniruddh V. Deshpande, Paul S. Foster, Andrew N. J. McKenzie, Ari B. Molofsky, Philip M. Hansbro, M...> ;Frontiers in Immunology. 2019 Apr 16
185 citations
Adventitial Stromal Cells Define Group 2 Innate Lymphoid Cell Tissue Niches
Madelene W. Dahlgren, Stephen M. Jones, Kelly M. Cautivo, Alexandra Dubinin, Jorge F. Ortiz-Carpena, Sepideh Farhat, Kevin Shengyang Yu, Katharine Lee, Chaoqun Wang, A...> ;Immunity. 2019 Mar 19
284 citations
Tissue signals imprint ILC2 identity with anticipatory function.
Roberto R. Ricardo-Gonzalez, Steven J. Van Dyken, Christoph Schneider, Jinwoo Lee, Jesse C. Nussbaum, Hong-Erh Liang, Dedeepya Vaka, Walter L. Eckalbar, Ari B. Molofsk...> ;Nature Immunology. 2018 Sep 10
12 citations
All along the watchtower: group 2 innate lymphoid cells in allergic responses.
Madelene W. Dahlgren, Ari B. Molofsky> ;Current Opinion in Immunology. 2018 Jun 1
18 citations
B Lymphoblastic Leukemia/Lymphoma With Burkitt-like Morphology and IGH/MYC Rearrangement: Report of 3 Cases in Adult Patients.
Yiting Li, Gunjan Gupta, Ari B. Molofsky, Yi Xie, Nader Shihabi, Jane McCormick, Elaine S. Jaffe> ;The American Journal of Surgical Pathology. 2018 Feb 1
355 citations
Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development.
Ilia D. Vainchtein, Gregory Chin, Frances S. Cho, Kevin W. Kelley, John G. Miller, Elliott C. Chien, Shane A. Liddelow, Phi T. Nguyen, Hiromi Nakao-Inoue, Leah C. Dorm...> ;Science. 2018 Mar 16
The Skinny: Pancreatic ILC2s Promote Insulin Secretion.
Kelly M. Cautivo, Ari B. Molofsky> ;Immunity. 2017 Nov 21
162 citations
A tissue checkpoint regulates type 2 immunity
Steven J. Van Dyken, Jesse C. Nussbaum, Jinwoo Lee, Ari B. Molofsky, Hong-Erh Liang, Joshua L. Pollack, Rachel E. Gate, Genevieve E. Haliburton, Chun Jimmie Ye, Alexan...> ;Nature Immunology. 2016 Dec 1
33 citations
Regulation of metabolic health and adipose tissue function by group 2 innate lymphoid cells.
Kelly M. Cautivo, Ari B. Molofsky> ;European Journal of Immunology. 2016 Jun 1
325 citations
InterleuKin-33 And Interferon-Γ Counter-Regulate Group 2 Innate Lymphoid Cell Activation During Immune Perturbation
Ari B. Molofsky, Frédéric Van Gool, Hong-Erh Liang, Steven J. Van Dyken, Jesse C. Nussbaum, Jinwoo Lee, Jeffrey A. Bluestone, Richard M. Locksley> ;Immunity. 2015 Jul 21
424 citations
Interleukin-33 in tissue homeostasis, injury and inflammation
Ari B. Molofsky, Adam K. Savage, Richard M. Locksley> ;Immunity. 2015 Jun 16
31 citations
A worm of one's own: how helminths modulate host adipose tissue function and metabolism
Bruno Guigas, Ari B. Molofsky> ;Trends in Parasitology. 2015 Sep 1
516 citations
Activated type 2 innate lymphoid cells regulate beige fat biogenesis
Min Woo Lee, Justin I. Odegaard, Lata Mukundan, Yifu Qiu, Ari B. Molofsky, Jesse C. Nussbaum, Karen Yun, Richard M. Locksley, Ajay Chawla> ;Cell. 2015 Jan 15
82 citations
Interleukin-5-producing group 2 innate lymphoid cells control eosinophilia induced by interleukin-2 therapy.
Frédéric Van Gool, Ari B. Molofsky, Malika M. Morar, Michelle Rosenzwajg, Hong-Erh Liang, David Klatzmann, Richard M. Locksley, Jeffrey A. Bluestone> ;Blood. 2014 Dec 4
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Journal Articles

Tissue Signals Imprint ILC2 Identity with Anticipatory Function
Richard M Locksley, Jinwoo Lee, Jesse C Nussbaum, Ari B Molofsky, David J Erle, Nature

Press Mentions

Discovery of a Subset of T Cells Points to a New Treatment for COPD ExacerbationsFebruary 24th, 2023
Susceptibility to Pathogenic T Cells in Chronic Lung Disease May Have Genetic BasisFebruary 23rd, 2023
Brain’s Immune System May Be Key to Better Treatments for Psychiatric DisordersJanuary 3rd, 2018

Hospital Affiliations

UCSF Medical CenterSan Francisco, California
Kaiser Permanente San Francisco Medical CenterSan Francisco, California