AriLZaimanMD

Pulmonology • Baltimore, MD

Critical Care Medicine, Pleural Disease

Assistant Professor, Medicine, Johns Hopkins University School of Medicine

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Office
6565 N Charles St
Baltimore, MD 21204
Phone+1 443-849-2000
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Education & Training

Johns Hopkins UniversityFellowship, Pulmonary Disease and Critical Care Medicine, 2000 - 2005
University of MarylandResidency, Internal Medicine, 1997 - 1999
Albert Einstein College of MedicineClass of 1997

Certifications & Licensure

MD State Medical License 2000 - 2025
American Board of Internal Medicine Critical Care Medicine
American Board of Internal Medicine Pulmonary Disease

Clinical Trials

Effects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH) Start of enrollment: 2006 May 01
Completed
Phase 4

Publications & Presentations

PubMed

21 citations
Severity of systemic sclerosis-associated pulmonary arterial hypertension in African Americans.
Isabel Blanco, Stephen C. Mathai, Majid Shafiq, Danielle Boyce, Todd M. Kolb, Hala El Chami, Laura K. Hummers, Traci Housten, Neal F. Chaisson, Ari L. Zaiman, Fredrick...> ;Medicine. 2014 Jul 1
67 citations
Pulmonary arterial hypertension: MR imaging-derived first-pass bolus kinetic parameters are biomarkers for pulmonary hemodynamics, cardiac function, and ventricular re...
Jan Skrok, Monda L. Shehata, Stephen C. Mathai, Reda E. Girgis, Ari L. Zaiman, James O. Mudd, Danielle Boyce, Noah Lechtzin, Joao A.C. Lima, David A. Bluemke, Paul M. ...> ;Radiology. 2012 Jun 1
50 citations
Erythroid-Specific Transcriptional Changes in PBMCs from Pulmonary Hypertension Patients
Chris Cheadle, Alan E. Berger, Stephen C. Mathai, Dmitry N. Grigoryev, Tonya Watkins, Yumiko Sugawara, Sangjucta Barkataki, Jinshui Fan, Meher Preethi Boorgula, Laura ...> ;Plos One. 2012 Apr 24
73 citations
Digoxin inhibits development of hypoxic pulmonary hypertension in mice
Edsel M. Abud, Julie Maylor, Clark Undem, Arjun Punjabi, Ari L. Zaiman, Allen C. Myers, J. T. Sylvester, Gregg L. Semenza, Larissa A. Shimoda> ;Proceedings of the National Academy of Sciences of the United States of America. 2012 Jan 24
33 citations
A Critical Role for the Protein Apoptosis Repressor With Caspase Recruitment Domain in Hypoxia-Induced Pulmonary Hypertension
Ari L. Zaiman, Rachel L. Damico, Alan Thoms-Chesley, D. Clark Files, Priya Kesari, Laura Johnston, Mara Swaim, Shehzin Mozammel, Alan C. Myers, Marc K. Halushka, Hazim...> ;Circulation. 2011 Dec 6
87 citations
MicroRNA profiling of diverse endothelial cell types
Matthew N. McCall, Oliver A. Kent, Jianshi Yu, Karen Fox-Talbot, Ari L. Zaiman, Marc K. Halushka> ;BMC Medical Genomics. 2011 Nov 2
92 citations
Tricuspid Annular Plane Systolic Excursion Is a Robust Outcome Measure in Systemic Sclerosis-associated Pulmonary Arterial Hypertension
Stephen C. Mathai, Christopher T. Sibley, Paul R. Forfia, James O. Mudd, Micah R. Fisher, Ryan J. Tedford, Noah Lechtzin, Danielle Boyce, Laura K. Hummers, Traci Houst...> ;The Journal of Rheumatology. 2011 Nov 1
264 citations
Pivotal role of cardiomyocyte TGF-β signaling in the murine pathological response to sustained pressure overload
Norimichi Koitabashi, Thomas Danner, Ari L. Zaiman, Yigal M. Pinto, Janelle Rowell, Joseph L. Mankowski, Dou Zhang, Taishi Nakamura, Eiki Takimoto, David A. Kass> ;The Journal of Clinical Investigation. 2011 Jun 1
96 citations
Systemic sclerosis–related pulmonary hypertension associated with interstitial lung disease: Impact of pulmonary arterial hypertension therapies
Jérôme Le Pavec, Reda E. Girgis, Noah Lechtzin, Stephen C. Mathai, David Launay, Laura K. Hummers, Ari L. Zaiman, Olivier Sitbon, Gérald Simonneau, Marc Humbert, Paul ...> ;Arthritis and Rheumatism. 2011 Aug 1
22 citations
Phosphodiesterase-5A (PDE5A) is localized to the endothelial caveolae and modulates NOS3 activity
Milena A. Gebska, Blake K. Stevenson, Anna R. Hemnes, Trinity J. Bivalacqua, Azeb Haile, Geoffrey G. Hesketh, Christopher I. Murray, Ari L. Zaiman, Marc K. Halushka, N...> ;Cardiovascular Research. 2011 May 1
133 citations
Outcomes of hospitalisation for right heart failure in pulmonary arterial hypertension
Arantza Campo, S.C. Mathai, J. Le Pavec, Ari L. Zaiman, Laura K. Hummers, Danielle Boyce, Traci Housten, Noah Lechtzin, Hala El Chami, Reda E. Girgis, Paul M. Hassoun> ;The European Respiratory Journal. 2011 Jan 1
73 citations
Schistosomiasis-Induced Experimental Pulmonary Hypertension : Role of Interleukin-13 Signaling
Brian B. Graham, Margaret M. Mentink-Kane, Hazim El-Haddad, Shawn M. Purnell, Li Zhang, Ari L. Zaiman, Elizabeth F. Redente, David W. H. Riches, Paul M. Hassoun, Angel...> ;The American Journal of Pathology. 2010 Sep 1
172 citations
Hemodynamic predictors of survival in scleroderma-related pulmonary arterial hypertension.
Aranzazu Campo, Stephen C. Mathai, Jérôme Le Pavec, Ari L. Zaiman, Laura K. Hummers, Danielle Boyce, Traci Housten, Hunter C. Champion, Noah Lechtzin, Fredrick M. Wigl...> ;American Journal of Respiratory and Critical Care Medicine. 2010 Jul 15
95 citations
Disproportionate elevation of N-terminal pro-brain natriuretic peptide in scleroderma-related pulmonary hypertension
Stephen C. Mathai, Monica Bueso, Laura K. Hummers, Danielle Boyce, Noah Lechtzin, J. Le Pavec, Arantza Campo, Hunter C. Champion, Traci Housten, Paul R. Forfia, Ari L....> ;The European Respiratory Journal. 2010 Jan 1
163 citations
Avoidance of Transient Cardiomyopathy in Cardiomyocyte-Targeted Tamoxifen-Induced MerCreMer Gene Deletion Models
Norimichi Koitabashi, Djahida Bedja, Ari L. Zaiman, Yigal M. Pinto, Manling Zhang, Kathleen L. Gabrielson, Eiki Takimoto, David A. Kass> ;Circulation Research. 2009 Jul 2
105 citations
Treatment of sarcoidosis-associated pulmonary hypertension. A two-center experience.
Christopher Barnett, Eric J. Bonura, Steven D. Nathan, Shahzad Ahmad, Oksana A. Shlobin, Kwabena Osei, Ari L. Zaiman, Paul M. Hassoun, David R. Moller, Scott D. Barnet...> ;Chest. 2009 Jun 1
181 citations
Survival in pulmonary hypertension associated with the scleroderma spectrum of diseases: impact of interstitial lung disease.
Stephen C. Mathai, Laura K. Hummers, Hunter C. Champion, Fredrick M. Wigley, Ari L. Zaiman, Paul M. Hassoun, Reda E. Girgis> ;Arthritis and Rheumatism. 2009 Feb 1
133 citations
PDE5A Inhibitor Treatment of Persistent Pulmonary Hypertension After Mechanical Circulatory Support
Ryan J. Tedford, Anna R. Hemnes, Stuart D. Russell, Ilan S. Wittstein, Mobusher Mahmud, Ari L. Zaiman, Stephen C. Mathai, David R. Thiemann, Paul M. Hassoun, Reda E. G...> ;Circulation. Heart Failure. 2008 Nov 1
107 citations
Role of the TGF-β/Alk5 Signaling Pathway in Monocrotaline-induced Pulmonary Hypertension
Ari L. Zaiman, Megan Podowski, Satya Medicherla, Kimberley Gordy, Fang Xu, Lijie Zhen, Larissa A. Shimoda, Enid Neptune, Linda S. Higgins, Alison Murphy, Sarvajit Chak...> ;American Journal of Respiratory and Critical Care Medicine. 2008 Apr 15
66 citations
Identification of candidate genes in scleroderma-related pulmonary arterial hypertension.
Dmitry N. Grigoryev, Stephen C. Mathai, Micah R. Fisher, Reda E. Girgis, Ari L. Zaiman, Traci Housten-Harris, Christopher Cheadle, Li Gao, Laura K. Hummers, Hunter C. ...> ;Translational Research. 2008 Apr 1
121 citations
PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation.
Anna R. Hemnes, Ari L. Zaiman, Hunter C. Champion> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2008 Jan 1
118 citations
Addition of sildenafil to bosentan monotherapy in pulmonary arterial hypertension.
Stephen C. Mathai, Reda E. Girgis, Micah R. Fisher, Hunter C. Champion, Traci Housten-Harris, Ari L. Zaiman, Paul M. Hassoun> ;The European Respiratory Journal. 2007 Mar 1
57 citations
One hundred years of research in the pathogenesis of pulmonary hypertension.
Ari L. Zaiman, Iwona Fijalkowska, Paul M. Hassoun, Rubin M. Tuder> ;American Journal of Respiratory Cell and Molecular Biology. 2005 Nov 1
25 citations
Intracellular interaction of myosin light chain kinase with macrophage migration inhibition factor (MIF) in endothelium.
Raj Wadgaonkar, Steven M. Dudek, Ari L. Zaiman, Laura Linz-McGillem, Alexander D. Verin, Saule Nurmukhambetova, Lewis H. Romer, Joe G.N. Garcia> ;Journal of Cellular Biochemistry. 2005 Jul 1
102 citations
Impaired transforming growth factor-β signaling in idiopathic pulmonary arterial hypertension
Amy Richter, Michael E. Yeager, Ari L. Zaiman, Carlyne D. Cool, Norbert F. Voelkel, Rubin M. Tuder> ;American Journal of Respiratory and Critical Care Medicine. 2004 Dec 15
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Hospital Affiliations

Anne Arundel Medical CenterAnnapolis, Maryland
Greater Baltimore Medical CenterTowson, Maryland