ArthurR.ThompsonMD

Hematology • Seattle, WA

Physician

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Office
921 Terry Ave
Seattle, WA 98104
Phone+1 206-292-6570

Fax+1 206-292-8030
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Education & Training

New York Presbyterian Hospital (Cornell Campus)Internship, Internal Medicine, 1966 - 1967
University of Washington School of MedicineClass of 1966

Certifications & Licensure

WA State Medical License 1974 - 2025
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Hematology

Awards, Honors, & Recognition

Elected Member The American Society for Clinical Investigation, 1980
Investigator Alumnus Howard Hughes Medical Institute, 1973

Publications & Presentations

PubMed

17 citations
FVIII proteins with a modified immunodominant T-cell epitope exhibit reduced immunogenicity and normal FVIII activity
Ruth A. Ettinger, Joseph A. Liberman, Devi Gunasekera, Komal Puranik, Eddie A. James, Arthur R. Thompson, Kathleen P. Pratt> ;Blood Advances. 2018 Feb 27
19 citations
T cells from hemophilia A subjects recognize the same HLA-restricted FVIII epitope with a narrow TCR repertoire.
Ruth A. Ettinger, Pedro Paz, Eddie A. James, Devi Gunasekera, Fred Aswad, Arthur R. Thompson, Dana C. Matthews, Kathleen P. Pratt> ;Blood. 2016 Oct 20
15 citations
A Comparison of the ATP Generating Pathways Used by S. Typhimurium to Fuel Replication within Human and Murine Macrophage and Epithelial Cell Lines.
Enriqueta Garcia-Gutierrez, Amanda C. Chidlaw, Gwénaëlle Le Gall, Steven D. Bowden, Karsten Tedin, David J. Kelly, Arthur Thompson> ;Plos One. 2016 Mar 1
17 citations
Six amino acid residues in a 1200 Å2 interface mediate binding of factor VIII to an IgG4κ inhibitory antibody.
Jasper C. Lin, Ruth A. Ettinger, Jason T. Schuman, Ai-Hong Zhang, Muhammad Wamiq-Adhami, Phuong-Cac T. Nguyen, Shelley M. Nakaya-Fletcher, Komal Puranik, Arthur R. Tho...> ;Plos One. 2015 Jan 23
22 citations
Factor VIII mutation and desmopressin‐responsiveness in 62 patients with mild haemophilia A
D. Nance, Shelley N Fletcher, Douglas Bolgiano, Arthur R. Thompson, Neil C. Josephson, Barbara A. Konkle> ;Haemophilia. 2013 Sep 1
259 citations
F8 gene mutation type and inhibitor development in patients with severe hemophilia A: systematic review and meta-analysis
Samantha C. Gouw, H. Marijke van den Berg, Johannes Oldenburg, Jan Astermark, Philip G. de Groot, Maurizio Margaglione, Arthur R. Thompson, Waander L. van Heerde, Jori...> ;Blood. 2012 Mar 22
131 citations
Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients.
Amy D. Shapiro, Margaret V. Ragni, Leonard A. Valentino, Nigel S. Key, Neil C. Josephson, Jerry S. Powell, Gregory Cheng, Arthur R. Thompson, Jaya Goyal, Karen L. Tubr...> ;Blood. 2012 Jan 19
77 citations
The Mycotoxin Deoxynivalenol Potentiates Intestinal Inflammation by Salmonella Typhimurium in Porcine Ileal Loops
Virginie Vandenbroucke, Siska Croubels, An Martel, Elin Verbrugghe, Joline Goossens, Kim Van Deun, Filip Boyen, Arthur Thompson, Neil Shearer, Patrick De Backer, Fredd...> ;Plos One. 2011 Aug 31
49 citations
In non‐severe hemophilia A the risk of inhibitor after intensive factor treatment is greater in older patients: a case–control study
Christine L. Kempton, J. M. Soucie, Connie H. Miller, Craig Hooper, Miguel A. Escobar, A. J. Cohen, Nigel S. Key, Arthur R. Thompson, Thomas C. Abshire> ;Journal of Thrombosis and Haemostasis. 2010 Oct 1
42 citations
HLA-DR-restricted T-cell responses to factor VIII epitopes in a mild haemophilia A family with missense substitution A2201P
Ruth A. Ettinger, Eddie A. James, William W. Kwok, Arthur R. Thompson, Kathleen P. Pratt> ;Haemophilia. 2010 May 1
52 citations
CD4 + FOXP3 + regulatory T cells confer long-term regulation of factor VIII–specific immune responses in plasmid-mediated gene therapy–treated hemophilia mice
Carol H. Miao, Benjamin R. Harmeling, Steven F. Ziegler, Benjamin C. Yen, Troy R. Torgerson, Liping Chen, Roger J. Yau, Baowei Peng, Arthur R. Thompson, Hans D. Ochs, ...> ;Blood. 2009 Nov 5
57 citations
Lineages of human T-cell clones, including T helper 17/T helper 1 cells, isolated at different stages of anti-factor VIII immune responses.
Ruth A. Ettinger, Eddie A. James, William W. Kwok, Arthur R. Thompson, Kathleen P. Pratt> ;Blood. 2009 Aug 13
21 citations
Bleeding symptoms and laboratory correlation in patients with severe von Willebrand disease.
Ara Metjian, C. Wang, Suman L. Sood, Adam Cuker, S. M. Peterson, J. M. Soucie, Barbara A. Konkle, Marjorie A. Boyd, Glen Roy, Edwin N. Forman, Jean Marandola, Alan C. ...> ;Haemophilia. 2009 Jul 10
4 citations
Factor VIII mutations in 42 Moldovan haemophilia A families, including 12 that are novel.
N. Sirocova, V. Tsourea, M. Vicol, N. Barbacar, S. M. Nakaya, Arthur R. Thompson, Kathleen P. Pratt> ;Haemophilia. 2009 Jul 1
139 citations
Inhibitors of Factor VIII in Black Patients with Hemophilia
Kevin R. Viel, Afshin Ameri, Thomas C. Abshire, Rathi V. Iyer, Raymond G. Watts, Charles L. Lutcher, Cynthia Channell, Shelley A. Cole, Karl Fernstrom, Shelley Nakaya,...> ;The New England Journal of Medicine. 2009 Apr 16
26 citations
B-Cell and T-Cell Epitopes in Anti-factor VIII Immune Responses
Kathleen P. Pratt, Arthur R. Thompson> ;Clinical Reviews in Allergy & Immunology. 2009 Jan 30
1 citations
A family with combined mutations of the hemophilia A and X-linked adrenoleukodystrophy genes
Brent L. Fogel, Pari Young, Arthur R. Thompson, Susan Perlman> ;Neurogenetics. 2008 Jul 1
28 citations
The factor VIII C1 domain contributes to platelet binding
Ting-Chang Hsu, Kathleen P. Pratt, Arthur R. Thompson> ;Blood. 2008 Jan 1
67 citations
T-cell responses over time in a mild hemophilia A inhibitor subject: epitope identification and transient immunogenicity of the corresponding self-peptide.
Eddie A. James, William W. Kwok, Ruth A. Ettinger, Arthur R. Thompson, Kathleen P. Pratt> ;Journal of Thrombosis and Haemostasis. 2007 Dec 1
41 citations
ELISA system for detection of immune responses to FVIII: a study of 246 samples and correlation with the Bethesda assay
Mervyn A. Sahud, Kathleen P. Pratt, Olga Zhukov, K. Qu, Arthur R. Thompson> ;Haemophilia. 2007 May 1
6 citations
Severe haemophilia B due to a 6 kb factor IX gene deletion including exon 4: non-homologous recombination associated with a shortened transcript from whole blood.
Ting-Chang Hsu, Shelley Nakaya, Arthur R. Thompson> ;Thrombosis and Haemostasis. 2007 Feb 1
13 citations
Ethical issues in haemophilia.
Donna DiMichele, Ampaiwan Chuansumrit, Alex John London, Arthur R. Thompson, C. G. Cooper, R. M. Killian, Lainie Friedman Ross, David Lillicrap, Jonathan Kimmelman> ;Haemophilia. 2006 Jul 1
26 citations
Von Willebrand's disease: clinical management.
Augusto B. Federici, Giancarlo Castaman, Arthur R. Thompson, Erik Berntorp> ;Haemophilia. 2006 Jul 1
89 citations
Genetic diagnosis of haemophilia and other inherited bleeding disorders.
Flora Peyvandi, Giridhara R. Jayandharan, Mammen Chandy, Arun Srivastava, S. M. Nakaya, M. J. Johnson, Arthur R. Thompson, Anne Goodeve, Isabella Garagiola, Silvia Lav...> ;Haemophilia. 2006 Apr 27
48 citations
Immunomodulation of transgene responses following naked DNA transfer of human factor VIII into hemophilia A mice
Carol H. Miao, Peiqing Ye, Arthur R. Thompson, David J. Rawlings, Hans D. Ochs> ;Blood. 2005 Nov 16
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Grant Support

B-Cell Responses To Clotting Factor VIIINational Heart, Lung, And Blood Institute2004–2007
Small Instrumentation GrantNational Heart, Lung, And Blood Institute1993
Intrinsic System Clotting: Structure And FunctionNational Heart, Lung, And Blood Institute1989–1993
Pathobiology Of Human Factor IX: Structure And FunctionNational Heart, Lung, And Blood Institute1987
Pathobiology Of Human Factor IX: Structure And FunctionNational Heart, Lung, And Blood Institute1985–1986

ArthurR.ThompsonMD

Dr. Thompson is on Doximity

Education & Training

Certifications & Licensure

Awards, Honors, & Recognition

Publications & Presentations

Grant Support

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