ArthurWeissMD

PubMed

• Cbl-b mitigates the responsiveness of naive CD8T cells that experience extensive tonic T cell receptor signaling.
  Joel Eggert, Wendy M Zinzow-Kramer, Yuesong Hu, Elizabeth M Kolawole, Yuan-Li Tsai, Arthur Weiss, Brian D Evavold, Khalid Salaita, Christopher D Scharer, Byron B Au-Yeung> ;Science Signaling. 2024 Feb 6
• 1 citations
  TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments.
  Yuan-Li Tsai, Marcel Arias-Badia, Theresa A Kadlecek, Yee May Lwin, Aahir Srinath, Neel H Shah, Zhi-En Wang, Diane Barber, John Kuriyan, Lawrence Fong, Arthur Weiss> ;Immunity. 2023 Dec 12
• Peeking Into the Black Box of T Cell Receptor Signaling.
  Arthur Weiss> ;Annual Review of Immunology. 2023 Oct 3
• Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells.
  Trang T T Nguyen, Wen Lu, Wandi S Zhu, K Mark Ansel, Hong-Erh Liang, Arthur Weiss> ;Proceedings of the National Academy of Sciences of the United States of America. 2023 Jun 20
• 6 citations
  A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function.
  Wan-Lin Lo, Miriam Kuhlmann, Gabrielle Rizzuto, H Atakan Ekiz, Elizabeth M Kolawole, Monica P Revelo, Rakieb Andargachew, Zhongmei Li, Yuan-Li Tsai, Alexander Marson, ...> ;Nature Immunology. 2023 Apr 1
• Cold Spring Harbor Laboratory 2022: emerging insights and viewpoints in immunology.
  Jonathan C Kagan, Ellen V Rothenberg, Arthur Weiss, Alexander Y Rudensky, Stephen T Smale> ;Trends in Immunology. 2023 Apr 1
• Accumulation of TCR signaling from self-antigens in naive CD8 T cells mitigates early responsiveness.
  Joel Eggert, Wendy M Zinzow-Kramer, Yuesong Hu, Yuan-Li Tsai, Arthur Weiss, Khalid Salaita, Christopher D Scharer, Byron B Au-Yeung> ;Biorxiv. 2023 Jan 28
• 5 citations
  The phosphatidylinositol-transfer protein Nir3 promotes PI(4,5)Preplenishment in response to TCR signaling during T cell development and survival.
  Wen Lu, Ynes A Helou, Krishna Shrinivas, Jen Liou, Byron B Au-Yeung, Arthur Weiss> ;Nature Immunology. 2023 Jan 1
• 9 citations
  Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells.
  Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Januso...> ;Nature Immunology. 2023 Jan 1
• 15 citations
  ZAP70, too little, too much can lead to autoimmunity.
  Judith F Ashouri, Wan-Lin Lo, Trang T T Nguyen, Lin Shen, Arthur Weiss> ;Immunological Reviews. 2022 May 1
• 10 citations
  Reversible phosphorylation of cyclin T1 promotes assembly and stability of P-TEFb
  Fang Huang, Trang Nguyen, Ignacia Echeverria, Rakesh Ramachandran, Daniele C. Cary, Hana Paculova, Andrej Sali, Arthur Weiss, Boris Matija Peterlin, Koh Fujinaga> ;Elife. 2021 Nov 25
• 5 citations
  Acute Csk inhibition hinders B cell activation by constraining the PI3 kinase pathway
  Wen Lu, Katarzyna M. Skrzypczynska, Arthur Weiss> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Oct 26
• 10 citations
  Cbl-b deficiency prevents functional but not phenotypic T cell anergy.
  Trang Nguyen, Zhi-En Wang, Lin Shen, Andrew Schroeder, Walter L. Eckalbar, Arthur Weiss> ;The Journal of Experimental Medicine. 2021 Jul 5
• 6 citations
  Itk Promotes the Integration of TCR and CD28 Costimulation through Its Direct Substrates SLP-76 and Gads.
  Enas Hallumi, Rose Shalah, Wan-Lin Lo, Jasmin Corso, Ilana Oz, Dvora Beach, Samuel Wittman, Amy Isenberg, Meirav Sela, Henning Urlaub, Arthur Weiss, Deborah Yablonski> ;Journal of Immunology. 2021 Apr 30
• 12 citations
  Adapting T Cell Receptor Ligand Discrimination Capability via LAT.
  Wan-Lin Lo, Arthur Weiss> ;Frontiers in Immunology. 2021 Apr 16
• 7 citations
  A disease-associated mutation that weakens ZAP70 autoinhibition enhances responses to weak and self-ligands
  Lin Shen, Mehrdad Matloubian, Theresa A. Kadlecek, Arthur Weiss> ;Science Signaling. 2021 Feb 2
• 26 citations
  How the T cell signaling network processes information to discriminate between self and agonist ligands.
  Raman Ganti, Wan-Lin Lo, Darren McAffee, Jay T. Groves, Arthur Weiss, Arup K. Chakraborty> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Oct 20
• 69 citations
  CD45 functions as a signaling gatekeeper in T cells
  Adam H. Courtney, Alexey A. Shvets, Wen Lu, Gloria Griffante, Marianne Mollenauer, Veronika Horkova, Wan-Lin Lo, Steven Yu, Ondrej Stepanek, Arup K. Chakraborty, Arthu...> ;Science Signaling. 2019 Oct 22
• 50 citations
  Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination.
  Wan-Lin Lo, Neel H. Shah, Sara A. Rubin, Weiguo Zhang, Veronika Horkova, Ian R Fallahee, Ondrej Stepanek, Leonard I. Zon, John Kuriyan, Arthur Weiss> ;Nature Immunology. 2019 Oct 14
• 19 citations
  Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis.
  Judith F. Ashouri, Lih-Yun Hsu, Steven Yu, Dmitry Rychkov, Yiling Chen, Debra A. Cheng, Marina Sirota, Eric Hansen, Lisa L. Lattanza, Julie Zikherman, Arthur Weiss> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Sep 10
• 37 citations
  Adaptation by naïve CD4+ T cells to self-antigen–dependent TCR signaling induces functional heterogeneity and tolerance
  Wendy M. Zinzow-Kramer, Arthur Weiss, Byron B. Au-Yeung> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Jul 23
• 32 citations
  Switch-like activation of Bruton's tyrosine kinase by membrane-mediated dimerization.
  Jean K. Chung, Laura M. Nocka, Aubrianna Decker, Qi Wang, Theresa A. Kadlecek, Arthur Weiss, John Kuriyan, Jay T. Groves> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 May 28
• 34 citations
  CRACR2a is a calcium-activated dynein adaptor protein that regulates endocytic traffic.
  Yuxiao Wang, Walter Huynh, Taylor D. Skokan, Wen Lu, Arthur Weiss, Ronald D. Vale> ;The Journal of Cell Biology. 2019 May 6
• 34 citations
  The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions
  Zoltan Nagy, Timo Vögtle, Mitchell J. Geer, Jun Mori, Silke Heising, Giada Di Nunzio, Ralph Gareus, Alexander Tarakhovsky, Arthur Weiss, Benjamin G. Neel, Guillaume E....> ;Blood. 2019 Jan 24
• 97 citations
  Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT.
  Wan-Lin Lo, Neel H. Shah, Nagib Ahsan, Veronika Horkova, Ondrej Stepanek, Arthur R. Salomon, John Kuriyan, Arthur Weiss> ;Nature Immunology. 2018 Jun 18
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