AshleyMcgarryHoughtonMD

PubMed

• 12 citations
  Impact of HPV status on immune responses in head and neck squamous cell carcinoma.
  Hannan A Qureshi, Xiaodong Zhu, Grace H Yang, Melissa Steadele, Robert H Pierce, Neal D Futran, Sylvia M Lee, Eduardo Méndez, A McGarry Houghton> ;Oral Oncology. 2022 Apr 1
• 12 citations
  Identification of Novel Low-Density Neutrophil Markers Through Unbiased High-Dimensional Flow Cytometry Screening in Non-Small Cell Lung Cancer Patients
  Paulina Valadez-Cosmes, Kathrin Maitz, Oliver Kindler, Sofia Raftopoulou, Melanie Kienzl, Ana Santiso, Zala Nikita Mihalic, Luka Brcic, Jörg Lindenmann, Melanie Fediuk...> ;Frontiers in Immunology. 2021 Aug 13
• 14 citations
  Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness.
  Haritha Mathsyaraja, Jonathen Catchpole, Brian Freie, Emily Eastwood, Ekaterina Babaeva, Michael Geuenich, Pei Feng Cheng, Jessica Ayers, Ming Yu, Nan Wu, Sitapriya Mo...> ;Elife. 2021 Jul 8
• 140 citations
  Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade.
  Shivani Srivastava, Scott N. Furlan, Carla A. Jaeger-Ruckstuhl, Megha Sarvothama, Carolina Berger, Kimberly S. Smythe, Sarah M. Garrison, Jennifer M. Specht, Sylvia Le...> ;Cancer Cell. 2021 Feb 8
• 5 citations
  A case series of morbid COPD exacerbations during immune checkpoint inhibitor therapy in cancer patients.
  Viswam S. Nair, Keith D. Eaton, A. McGarry Houghton> ;Respiratory Medicine Case Reports. 2021 Jan 1
• 16 citations
  Good cops turn bad: The contribution of neutrophils to immune-checkpoint inhibitor treatment failures in cancer.
  Huajia Zhang, A. McGarry Houghton> ;Pharmacology & Therapeutics. 2021 Jan 1
• 37 citations
  MYCN drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity.
  Eli Grunblatt, Nan Wu, Huajia Zhang, Xiaoli Liu, Justin P. Norton, Yamini M. Ohol, Paul Leger, Joseph B. Hiatt, Emily Eastwood, Rhiana Thomas, Ali H. Ibrahim, Deshui J...> ;Genes & Development. 2020 Sep 1
• 102 citations
  Neutrophil content predicts lymphocyte depletion and anti-PD1 treatment failure in NSCLC
  Julia Kargl, Xiaodong Zhu, Huajia Zhang, Grace H. Y. Yang, Travis J. Friesen, Melissa Shipley, Dean Y. Maeda, John A. Zebala, Jill McKay-Fleisch, Gavin Meredith, Afshi...> ;JCI Insight. 2019 Dec 19
• 9 citations
  Cooperation of oncolytic virotherapy with VEGF-neutralizing antibody treatment in IDH wildtype glioblastoma depends on MMP9
  Hans-Georg Wirsching, Sonali Arora, Huajia Zhang, Frank Szulzewsky, Patrick J. Cimino, Christophe Quéva, A. McGarry Houghton, Joseph C. Glorioso, Michael Weller, Eric ...> ;Neuro-Oncology. 2019 Dec 17
• 24 citations
  Arming oHSV with ULBP3 drives abscopal immunity in lymphocyte-depleted glioblastoma.
  Hans-Georg Wirsching, Huajia Zhang, Frank Szulzewsky, Sonali Arora, Paola Grandi, Patrick J. Cimino, Nduka Amankulor, Jean S. Campbell, Lisa McFerrin, Siobhan S. Pattw...> ;JCI Insight. 2019 Jul 11
• 31 citations
  Comparison of prediction models with radiological semantic features and radiomics in lung cancer diagnosis of the pulmonary nodules: a case-control study.
  Wei Wu, Larry Pierce, Yuzheng Zhang, Sudhakar Pipavath, Timothy W. Randolph, Kristin J. Lastwika, Paul D. Lampe, A. McGarry Houghton, Haining Liu, Liming Xia, Paul E. ...> ;European Radiology. 2019 May 21
• 58 citations
  Endogenous CD4+ T Cells Recognize Neoantigens in Lung Cancer Patients, Including Recurrent Oncogenic KRAS and ERBB2 (Her2) Driver Mutations.
  Joshua R. Veatch, Brenda Jesernig, Julia Kargl, Matthew Fitzgibbon, Sylvia Lee, Christina S. Baik, Renato G. Martins, A. McGarry Houghton, Stanley R. Riddell> ;Cancer Immunology Research. 2019 Jan 1
• 33 citations
  Alveolar macrophage apoptosis-associated bacterial killing helps prevent murine pneumonia
  Julie A. Preston, Martin A. Bewley, Helen M. Marriott, A. McGarry Houghton, Mohammed Mohasin, Jamil Jubrail, Lucy Morris, Yvonne L. Stephenson, Simon S. Cross, David R...> ;American Journal of Respiratory and Critical Care Medicine. 2019 Jul 1
• 11 citations
  Common Mechanisms Linking Chronic Obstructive Pulmonary Disease and Lung Cancer.
  A. McGarry Houghton> ;Annals of the American Thoracic Society. 2018 Dec 1
• 17 citations
  Tumor-derived Autoantibodies Identify Malignant Pulmonary Nodules
  Kristin J. Lastwika, Julia Kargl, Yuzheng Zhang, Xiaodong Zhu, Edward Lo, David Shelley, Jon Ladd, Wei Wu, Paul E. Kinahan, Sudhakar Pipavath, Timothy W. Randolph, Mel...> ;American Journal of Respiratory and Critical Care Medicine. 2019 May 15
• 81 citations
  Tumor-infiltrating BRAFV600E-specific CD4+ T cells correlated with complete clinical response in melanoma
  Joshua R. Veatch, Sylvia Lee, Matthew Fitzgibbon, I-Ting Chow, Brenda Jesernig, Thomas M. Schmitt, Ying Ying Kong, Julia Kargl, A. McGarry Houghton, John A. Thompson, ...> ;The Journal of Clinical Investigation. 2018 Jan 23
• Macrophage-Dependent Cytoplasmic Transfer during Melanoma Invasion In Vivo.
  Roh-Johnson, M.,Shah, A. N.,Stonick, J. A.,Poudel, K. R.,Kargl, J.,Yang, G. H.,di Martino, J.,Hernandez, R. E.,Gast, C. E.,Zarour, L. R.,Antoku, S.,Houghton, A. M.,Bra...> ;Dev. Cell. 2017 Dec 06
• 66 citations
  Chronic Obstructive Pulmonary Disease Alters Immune Cell Composition and Immune Checkpoint Inhibitor Efficacy in Non–Small Cell Lung Cancer
  Nicholas M. Mark, Julia Kargl, Stephanie E. Busch, Grace H. Y. Yang, Heather E. Metz, Huajia Zhang, Jesse J. Hubbard, Sudhakar Pipavath, David K. Madtes, A. McGarry Ho...> ;American Journal of Respiratory and Critical Care Medicine. 2017 Sep 21
• 21 citations
  Matrix Metalloproteinase-28 Is a Key Contributor to Emphysema Pathogenesis
  Anne M. Manicone, Sina A. Gharib, Ke-Qin Gong, William E. Eddy, Matthew E. Long, Charles W. Frevert, William A. Altemeier, William C. Parks, A. McGarry Houghton> ;The American Journal of Pathology. 2017 Jun 1
• 259 citations
  Mutant IDH1 regulates the tumor-associated immune system in gliomas
  Nduka Amankulor, Youngmi Kim, Sonali Arora, Julia Kargl, Frank Szulzewsky, Mark L. Hanke, Daciana Margineantu, Aparna Rao, Hamid Bolouri, Jeff Delrow, David M. Hockenb...> ;Genes & Development. 2017 Apr 15
• 264 citations
  Neutrophils dominate the immune cell composition in non-small cell lung cancer
  Julia Kargl, Stephanie E. Busch, Grace H. Y. Yang, Kyoung-Hee Kim, Mark L. Hanke, Heather E. Metz, Jesse J. Hubbard, Sylvia Lee, David K. Madtes, Martin W. McIntosh, A...> ;Nature Communications. 2017 Feb 1
• 105 citations
  Lung Cancer Subtypes Generate Unique Immune Responses.
  Stephanie E. Busch, Mark L. Hanke, Julia Kargl, Heather E. Metz, David MacPherson, A. McGarry Houghton> ;Journal of Immunology. 2016 Oct 31
• 13 citations
  Insulin receptor substrate-1 deficiency drives a proinflammatory phenotype in KRAS mutant lung adenocarcinoma
  Heather E. Metz, Julia Kargl, Stephanie E. Busch, Kyoung-Hee Kim, Brenda F. Kurland, Shira Abberbock, Julie Randolph-Habecker, Sue E. Knoblaugh, Jay K. Kolls, Morris F...> ;Proceedings of the National Academy of Sciences of the United States of America. 2016 Aug 2
• 21 citations
  Enhancing autophagy with drugs or lung-directed gene therapy reverses the pathological effects of respiratory epithelial cell proteinopathy
  Tunda Hidvegi, Donna B. Stolz, John F. Alcorn, Samuel A. Yousem, Jieru Wang, Adriana S. Leme, A. McGarry Houghton, Pamela Hale, Michael Ewing, Houming Cai, Evelyn Akpa...> ;The Journal of Biological Chemistry. 2015 Dec 11
• 115 citations
  Matrix metalloproteinases in destructive lung disease.
  A. McGarry Houghton> ;Matrix Biology. 2015 May 1
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