AswinSomasundaramMD

PubMed

• A Pilot Study of Pembrolizumab in Combination With Y90 Radioembolization in Subjects With Poor Prognosis Hepatocellular Carcinoma.
  Shawn Yu, Menggang Yu, David M Mauro, Paul R Helft, William P Harris, Hanna K Sanoff, Matthew S Johnson, Bert O'Neil, Autumn Jackson McRee, Ashwin Somasundaram, Keane,...> ;The Oncologist. 2024 Mar 4
• 40 citations
  Therapeutic targeting of regulatory T cells in cancer.
  Feng Shan, Ashwin Somasundaram, Tullia C Bruno, Creg J Workman, Dario A A Vignali> ;Trends in Cancer. 2022 Nov 1
• 6 citations
  Systemic Immune Dysfunction in Cancer Patients Driven by IL6 Induction of LAG3 in Peripheral CD8+ T Cells.
  Ashwin Somasundaram, Anthony R Cillo, Caleb Lampenfeld, Creg J Workman, Sheryl Kunning, Lauren Oliveri, Maria Velez, Sonali Joyce, Michael Calderon, Rebekah Dadey, Dhi...> ;Cancer Immunology Research. 2022 Jul 1
• 16 citations
  Fewer LAG-3T Cells in Relapsing-Remitting Multiple Sclerosis and Type 1 Diabetes.
  Britta E Jones, Megan D Maerz, Henry T Bahnson, Ashwin Somasundaram, Cate Speake, Jane H Buckner, McCarthy, L., Lucas H McCarthy> ;Journal of Immunology. 2022 Feb 1
• 16 citations
  Prevalence of intratumoral regulatory T cells expressing neuropilin-1 is associated with poorer outcomes in patients with cancer.
  Christopher A Chuckran, Anthony R Cillo, Jessica Moskovitz, Abigail Overacre-Delgoffe, Ashwin S Somasundaram, Feng Shan, Grant C Magnon, Sheryl R Kunning, Irina Abecas...> ;Science Translational Medicine. 2021 Dec 8
• 4 citations
  SPaRTAN, a computational framework for linking cell-surface receptors to transcriptional regulators.
  Xiaojun Ma, Ashwin Somasundaram, Zengbiao Qi, Douglas J. Hartman, Harinder Singh, Hatice U. Osmanbeyoglu> ;Nucleic Acids Research. 2021 Sep 27
• 100 citations
  Intractable Coronavirus Disease 2019 (COVID-19) and Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Replication in a Chimeric Antigen Receptor-M...
  Matthew K Hensley, William Bain, Jana L. Jacobs, Sham Nambulli, Urvi M. Parikh, Anthony R. Cillo, Brittany Staines, Amy Heaps, Michele D. Sobolewski, Linda J. Rennick,...> ;Clinical Infectious Diseases. 2021 Aug 2
• 73 citations
  COVID-19 versus Non-COVID-19 Acute Respiratory Distress Syndrome: Comparison of Demographics, Physiologic Parameters, Inflammatory Biomarkers, and Clinical Outcomes.
  William Bain, Haopu Yang, Faraaz Ali Shah, Tomeka Suber, Callie Drohan, Nameer Al-Yousif, Rebecca S. DeSensi, N. Bensen, Caitlin Schaefer, Brian R. Rosborough, Ashwin ...> ;Annals of the American Thoracic Society. 2021 Jul 9
• 6 citations
  Bifurcated monocyte states are predictive of mortality in severe COVID-19
  Anthony R. Cillo, Ashwin Somasundaram, Feng Shan, Carly Cardello, Creg J. Workman, Georgios D Kitsios, Ayana T. Ruffin, Sheryl Kunning, Caleb Lampenfeld, Sayali Onkar,...> ;Biorxiv. 2021 Feb 10
• 29 citations
  Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding.
  Lawrence P. Andrews, Ashwin Somasundaram, Jessica M. Moskovitz, Andrea L. Szymczak-Workman, Chang Liu, Anthony R. Cillo, Huang Lin, Daniel P. Normolle, Kelly D. Moynih...> ;Science Immunology. 2020 Jul 17
• 76 citations
  Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity
  Chang Liu, Ashwin Somasundaram, Sasikanth Manne, Angela M. Gocher, Andrea L. Szymczak-Workman, Kate M. Vignali, Ellen N. Scott, Daniel P. Normolle, E. John Wherry, Eva...> ;Nature Immunology. 2020 Jul 13
• 5 citations
  Immune Checkpoint Blockade in Oncogene-Driven Non-Small-Cell Lung Cancer
  Ashwin Somasundaram, Mark A. Socinski, Liza C. Villaruz> ;Drugs. 2020 May 20
• 17 citations
  The Impact of Estrogen in the Tumor Microenvironment.
  Ashwin Somasundaram, Natalie J. Rothenberger, Laura P. Stabile> ;Advances in Experimental Medicine and Biology. 2020 Jan 1
• 117 citations
  The Role of the Estrogen Pathway in the Tumor Microenvironment.
  Natalie J. Rothenberger, Ashwin Somasundaram, Laura P. Stabile> ;International Journal of Molecular Sciences. 2018 Feb 19
• 51 citations
  A First-in-Class TWIST1 Inhibitor with Activity in Oncogene-Driven Lung Cancer
  Zachary A. Yochum, Jessica Cades, Lucia Mazzacurati, Neil M. Neumann, Susheel K. Khetarpal, Suman Chatterjee, Hailun Wang, Myriam A. Attar, Eric H.-B. Huang, Sarah N. ...> ;Molecular Cancer Research. 2017 Dec 1
• 78 citations
  The next generation of immunotherapy: keeping lung cancer in check
  Ashwin Somasundaram, Timothy F. Burns> ;Journal of Hematology & Oncology. 2017 Apr 24
• 10 citations
  Pembrolizumab in the treatment of metastatic non-small-cell lung cancer: patient selection and perspectives.
  Ashwin Somasundaram, Timothy F. Burns> ;Lung Cancer. 2017 Jan 11
• 15 citations
  Immune checkpoint blockade in lung cancer.
  Aswin Somasundaram, Mark A. Socinski, Liza C. Villaruz> ;Discovery Medicine. 2016 Aug 1
• 19 citations
  Personalized treatment of EGFR mutant and ALK-positive patients in NSCLC
  Aswin Somasundaram, Mark A. Socinski, Timothy F. Burns> ;Expert Opinion on Pharmacotherapy. 2014 Nov 15
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