AzizIsmailShaibaniMD,FACP, FAAN, FANA

Neurology • Houston, TX

Neuromuscular Medicine, Neurophysiology

Clinical Professor of Medicine, Baylor College of Medicine

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Office
6624 Fannin St
Suite 1670
Houston, TX 77030
Phone+1 713-795-0033

Fax+1 713-796-9302
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Summary

nerveandmuscle.org

Education & Training

Baylor College of MedicineFellowship, Clinical Neurophysiology, 1995
Baylor College of MedicineResidency, Neurology, 1991 - 1994
Conemaugh Memorial Medical CenterInternship, Transitional Year, 1990 - 1991
University of Mosul College of MedicineClass of 1983

Certifications & Licensure

TX State Medical License 1993 - 2025
UT State Medical License 1992 - 1994
American Board of Psychiatry and Neurology Neurology
American Board of Psychiatry and Neurology Clinical Neurophysiology
American Board of Psychiatry and Neurology Neuromuscular Medicine

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification eClinicalWorks EHR, eClinicalWorks LLC, 2013
Super Doctor SuperDoctors.com

Clinical Trials

Thymectomy Trial in Non-Thymomatous Myasthenia Gravis Patients Receiving Prednisone Therapy Start of enrollment: 2006 Jun 01
Completed
Phase 3
Efficacy of Methotrexate in Myasthenia Gravis Start of enrollment: 2009 Apr 01
Completed
Phase 2
Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Pain Associated With Diabetic Neuropathy Start of enrollment: 2014 Mar 01
Completed
Phase 2
Therapy in Amyotrophic Lateral Sclerosis (TAME) Start of enrollment: 2018 Nov 07
Completed
Phase 2
A Safety Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Painful Diabetic Neuropathy Start of enrollment: 2014 Jun 01
Completed
Phase 2
The Efficacy and Safety of Clonidine Hydrochloride Topical Gel, vs Clonidine Hydrochloride Gel Comparator to Treat Painful Diabetic Neuropathy Start of enrollment: 2015 Dec 01
Completed
Phase 2
An Efficacy and Safety Study of Ravulizumab in ALS Participants Start of enrollment: 2020 Mar 30
Terminated
Phase 3
Study to Assess Safety and Efficacy of Engensis in Painful Diabetic Peripheral Neuropathy Start of enrollment: 2020 Oct 09
Active, not recruiting
Phase 3
Myasthenia Gravis Inebilizumab Trial Start of enrollment: 2020 Aug 30
Active, not recruiting
Phase 3
A Study to Examine the Efficacy and Safety of Pozelimab and Cemdisiran Combination Therapy in Adult Patients With Symptomatic Generalized Myasthenia Gravis Start of enrollment: 2021 Dec 14
Recruiting
Phase 3
Roles: Principal Investigator, Contact
Study of M5049 in DM and PM Participants (NEPTUNIA) Start of enrollment: 2023 Jan 19
Recruiting
Phase 2
Roles: Principal Investigator
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Publications & Presentations

PubMed

A randomized, double-blind, placebo-controlled study of histone deacetylase type 6 inhibition for the treatment of painful diabetic peripheral neuropathy.
David Michelson, William W Chin, Robert H Dworkin, Roy Freeman, David N Herrmann, Ralph Mazitschek, Rodica Pop-Busui, Aziz Shaibani, James Vornov, Melissa Jones, Matth...> ;Pain Reports. 2023 Dec 1
Creating Placebo Nonresponders in the Lab.
Fabrizio Benedetti, Claudia Arduino, Aziz Shaibani, Wilma Thoen> ;The Journal of Pain. 2024 Apr 1
2 citations
Placebo and nocebo effects and mechanisms associated with pharmacological interventions: an umbrella review.
Elisa Frisaldi, Aziz Shaibani, Fabrizio Benedetti, Francesco Pagnini> ;BMJ Open. 2023 Oct 17
3 citations
Safety and efficacy of arimoclomol for inclusion body myositis: a multicentre, randomised, double-blind, placebo-controlled trial.
Pedro M Machado, Michael P McDermott, Thomas Blaettler, Claus Sundgreen, Anthony A Amato, Emma Ciafaloni, Miriam Freimer, Summer B Gibson, Sarah M Jones, Todd D Levine...> ;The Lancet. Neurology. 2023 Oct 1
1 citations
Placebo and nocebo responses in painful diabetic neuropathy: systematic review and meta-analysis.
Elisa Frisaldi, Jan Vollert, Husam Al Sultani, Fabrizio Benedetti, Aziz Shaibani> ;Pain. 2024 Jan 1
1 citations
Are Nocebo Effects in Adulthood Linked to Prenatal Maternal Cortisol Levels?
Fabrizio Benedetti, Martina Amanzio, Fabio Giovannelli, Karen Craigs-Brackhahn, Claudia Arduino, Aziz Shaibani> ;Clinical Neuropsychiatry. 2022 Oct 1
4 citations
Open-label nondeceptive placebo analgesia is blocked by the opioid antagonist naloxone.
Fabrizio Benedetti, Aziz Shaibani, Claudia Arduino, Wilma Thoen> ;Pain. 2023 May 1
Diagnostic Outcome of Genetic Testing for Neuromuscular Disorders in a Tertiary Center.
Husam Al Sultani, Komal Hafeez, Aziz Shaibani> ;Journal of Clinical Neuromuscular Disease. 2022 Sep 1
19 citations
Thirty Years of Neuroscientific Investigation of Placebo and Nocebo: The Interesting, the Good, and the Bad.
Fabrizio Benedetti, Elisa Frisaldi, Aziz Shaibani> ;Annual Review of Pharmacology and Toxicology. 2022 Jan 6
21 citations
COVID-19 Outcomes in Myasthenia Gravis Patients: Analysis From Electronic Health Records in the United States.
Youngran Kim, Xiaojin Li, Yan Huang, Minseon Kim, Aziz Shaibani, Kazim Sheikh, Guo-Qiang Zhang, Thy Phuong Nguyen> ;Frontiers in Neurology. 2022 Jan 1
1 citations
What is the role of placebo in neurotherapeutics
Elisa Frisaldi, Aziz Shaibani, Marco Trucco, Edoardo Milano, Fabrizio Benedetti> ;Expert Review of Neurotherapeutics. 2021 Nov 30
5 citations
Hypothalamic-Pituitary-Adrenal Activity in Adverse Events Reporting After Placebo Administration.
Fabrizio Benedetti, Martina Amanzio, Fabio Giovannelli, Karen Craigs-Brackhahn, Aziz Shaibani> ;Clinical Pharmacology and Therapeutics. 2021 Nov 1
8 citations
Safety and efficacy of oral levosimendan in people with amyotrophic lateral sclerosis (the REFALS study): a randomised, double-blind, placebo-controlled phase 3 trial.
Merit Cudkowicz, Angela Genge, Nicholas J. Maragakis, Susanne Petri, Leonard H. van den Berg, Valtteri V Aho, Toni Sarapohja, Mikko Kuoppamäki, Chris Garratt, Ammar Al...> ;The Lancet. Neurology. 2021 Oct 1
3 citations
Autosomal Dominant ANO5-Related Disorder Associated With Myopathy and Gnathodiaphyseal Dysplasia.
Aziz Shaibani, Shaida Khan, Marwan Shinawi> ;Neurology. Genetics. 2021 Jul 16
5 citations
Adult-Onset Spinal Muscular Atrophy due to Mutations in the VRK1 Gene.
Angela Sung, Paolo Moretti, Aziz Shaibani> ;Neurology. Genetics. 2021 Jun 22
4 citations
Mechanics of dystrophin deficient skeletal muscles in very young mice and effects of age.
Michael A. Lopez, Sherina Bontiff, Mary Adeyeye, Aziz Shaibani, Matthew S. Alexander, Shari Wynd, Aladin M. Boriek> ;American Journal of Physiology. Cell Physiology. 2021 May 12
25 citations
Gene therapy for diabetic peripheral neuropathy: A randomized, placebo-controlled phase III study of VM202, a plasmid DNA encoding human hepatocyte growth factor.
John A. Kessler, Aziz Shaibani, Christine N. Sang, Mark Christiansen, David Kudrow, Aaron I. Vinik, Nari Shin> ;Clinical and Translational Science. 2021 May 1
18 citations
Efficacy and Safety of Bimagrumab in Sporadic Inclusion Body Myositis: Long-term Extension of RESILIENT
Anthony A. Amato, Michael G. Hanna, Pedro Machado, Umesh A. Badrising, Hector Chinoy, Olivier Benveniste, Ananda Krishna Karanam, Min Wu, Laszlo Tanko, Agnes Annette S...> ;Neurology. 2021 Mar 23
14 citations
Understanding the mechanisms of placebo and nocebo effects.
Elisa Frisaldi, Aziz Shaibani, Fabrizio Benedetti> ;Swiss Medical Weekly. 2020 Sep 1
15 citations
Minimal manifestation status and prednisone withdrawal in the MGTX trial
Ikjae Lee, Hui-Chien Kuo, Inmaculada Aban, Gary R. Cutter, Tarrant McPherson, Henry J. Kaminski, Jon Sussman, Philipp Ströbel, Joel Oger, Gabriel Cea, Jeannine M. Heck...> ;Neurology. 2020 Aug 11
Preface.
Aziz Shaibani> ;Neurologic Clinics. 2020 Aug 1
1 citations
Refractory Chronic Immune-mediated Demyelinating Polyneuropathy
Aziz Shaibani, Husam Al Sultani> ;Neurologic Clinics. 2020 Aug 1
22 citations
Nocebo and the contribution of psychosocial factors to the generation of pain
Fabrizio Benedetti, Elisa Frisaldi, Diletta Barbiani, Eleonora Maria Camerone, Aziz Shaibani> ;Journal of Neural Transmission. 2020 Apr 1
72 citations
Safety and efficacy of intravenous bimagrumab in inclusion body myositis (RESILIENT): a randomised, double-blind, placebo-controlled phase 2b trial
Michael G. Hanna, Umesh A. Badrising, Olivier Benveniste, Thomas E. Lloyd, Merrilee Needham, Hector Chinoy, Masashi Aoki, Pedro Machado, Christina Liang, Katrina Reard...> ;The Lancet. Neurology. 2019 Sep 1
6 citations
The placebo response in myasthenia gravis assessed by quantitative myasthenia gravis score: A meta-analysis.
Elisa Frisaldi, Aziz Shaibani, Jan Vollert, B. Ferrero, Roberta Carrino, Hayan Dhamer Ibraheem, Lene Vase, Fabrizio Benedetti> ;Muscle & Nerve. 2019 Jun 1
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