BenGeorgeMD

Hematologic Oncology

Associate Professor of Medicine, William F. Stapp Endowed Chair, Director, Phase 1 Clinical Trials Program, Medical College of Wisconsin, Milwaukee

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Office
9200 W Wisconsin Ave
Neoplastic Diseases
Milwaukee, WI 53226
Phone+1 414-805-6800

Fax+1 414-805-6805
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Education & Training

Medical College of Wisconsin Affiliated HospitalsFellowship, Hematology and Medical Oncology, 2007 - 2010
Gundersen Lutheran Medical FoundationResidency, Internal Medicine, 2005 - 2007
University of ToledoInternship, Internal Medicine, 2004 - 2005
University of Kerala Medical CollegeClass of 1999

Certifications & Licensure

WI State Medical License 2007 - 2025
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013

Clinical Trials

BKM120 for Patients With PI3K-activated Tumors Start of enrollment: 2013 Mar 29
Completed
Phase 2
First in Human Study of M4344 in Participants With Advanced Solid Tumors Start of enrollment: 2015 Jan 26
Completed
Phase 1
Phase 1, First-in-human Study of Oral TP-1287 in Patients With Advanced Solid Tumors Start of enrollment: 2018 Dec 26
Terminated
Phase 1
Study of GNX102 in Patients With Advanced Solid Tumors Start of enrollment: 2020 Jul 29
Terminated
Phase 1
Futibatinib Versus Gemcitabine-Cisplatin Chemotherapy as First-Line Treatment of Patients With Advanced Cholangiocarcinoma Harboring FGFR2 Gene Rearrangements Start of enrollment: 2020 Mar 01
Active, not recruiting
Phase 3
Roles: Contact
Investigation of Profile-related Evidence Determining Individualized Cancer Therapy for Patients With Aggressive Malignancies and Poor Prognoses Start of enrollment: 2022 Dec 21
Recruiting
Phase 1, Phase 2
Roles: Principal Investigator, Contact
Circulating Tumor DNA (ctDNA) in Locally Advanced Esophageal and Gastroesophageal (GE) Junction Adenocarcinoma Start of enrollment: 2022 May 13
Recruiting
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

Transcriptomic-Based Microenvironment Classification Reveals Precision Medicine Strategies for Pancreatic Ductal Adenocarcinoma.
Ben George, Olga Kudryashova, Andrey Kravets, Samih Thalji, Subramaniam Malarkannan, Razelle Kurzrock, Ekatherina Chernyavskaya, Mariia Gusakova, Dmitry Kravchenko, Dm...> ;Gastroenterology. 2024 May 1
Characterization of an oligometastatic state in patients with metastatic pancreatic adenocarcinoma undergoing systemic chemotherapy.
de Ortiz de Choudens, S., Visotcky, A., Banerjee, A., Aldakkak, M., Tsai, S., Evans, D., Christians, K., Clarke, C., George, B., Shreenivas, A., Kamgar, M., Chakrabart...> ;Cancer Medicine. 2023 Dec 22
6 citations
ALK fusions in the pan-cancer setting: another tumor-agnostic target?
Aditya Shreenivas, Filip Janku, Mohamed A Gouda, Hui-Zi Chen, Ben George, Shumei Kato, Razelle Kurzrock> ;NPJ Precision Oncology. 2023 Sep 29
1 citations
A Paradigm Shift in Primary Liver Cancer Therapy Utilizing Genomics, Molecular Biomarkers, and Artificial Intelligence.
James Moroney, Juan Trivella, Ben George, Sarah B White> ;Cancers. 2023 May 17
2 citations
Definitive Chemoradiation Associated with Improved Survival Outcomes in Patients with Synchronous Oligometastatic Esophageal Cancer.
Thomas Matoska, Anjishnu Banerjee, Aditya Shreenivas, Lauren Jurkowski, Monica E Shukla, Elizabeth M Gore, Paul Linsky, Mario Gasparri, Ben George, Candice Johnstone, ...> ;Cancers. 2023 Apr 28
1 citations
Biliary Adverse Events During Neoadjuvant Therapy for Pancreatic Cancer.
Sam Z Thalji, Deemantha Fernando, Kulwinder S Dua, Srivats Madhavan, Phillip Chisholm, Zachary L Smith, Mohammed Aldakkak, Kathleen K Christians, Callisia N Clarke, Be...> ;Annals of Surgery. 2023 Dec 1
2 citations
Neoadjuvant chemotherapy for pancreatic cancer: Quality over quantity.
Sam Z Thalji, Mohammed Aldakkak, Kathleen K Christians, Callisia N Clarke, Ben George, Mandana Kamgar, Beth A Erickson, William A Hall, Phillip Chisholm, Naveen Kulkar...> ;Journal of Surgical Oncology. 2023 Jul 1
ASO Visual Abstract: CA19-9 Response to First-Line Neoadjuvant FOLFIRINOX and Second-Line Gemcitabine/ nab-Paclitaxel for Patients with Operable Pancreatic Cancer.
Sam Z Thalji, Mandana Kamgar, Ben George, Mohammed Aldakkak, Kathleen K Christians, Callisia N Clarke, Beth A Erickson, William A Hall, Parag P Tolat, Zachary L Smith,...> ;Annals of Surgical Oncology. 2023 May 1
3 citations
CA19-9 Response to First-Line Neoadjuvant FOLFIRINOX and Second-Line Gemcitabine/Nab-Paclitaxel for Patients with Operable Pancreatic Cancer.
Sam Z Thalji, Mandana Kamgar, Ben George, Mohammed Aldakkak, Kathleen K Christians, Callisia N Clarke, Beth A Erickson, William A Hall, Parag P Tolat, Zachary L Smith,...> ;Annals of Surgical Oncology. 2023 May 1
2 citations
Comprehensive genomic profiling: Does timing matter?
Bicky Thapa, Gulrayz Ahmed, Aniko Szabo, Mandana Kamgar, Deepak Kilari, Smitha Menon, Sherin Daniel, Jonathan Thompson, James Thomas, Ben George, Maahum Mehdi> ;Frontiers in Oncology. 2023 Jan 1
16 citations
Phase 1 Randomized Trial of Stereotactic Body Radiation Therapy Followed by Nivolumab plus Ipilimumab or Nivolumab Alone in Advanced/Unresectable Hepatocellular Carcin...
Aditya Juloori, Rohan R Katipally, Jeffrey M Lemons, Anurag K Singh, Renuka Iyer, Jared R Robbins, Ben George, William A Hall, Sean P Pitroda, Fauzia Arif, John Fung, ...> ;International Journal of Radiation Oncology, Biology, Physics. 2023 Jan 1
1 citations
Progression-free survival 2: Is it ready for prime time?
Ben George, Razelle Kurzrock> ;Cancer. 2022 Apr 1
Long term clinical outcomes and associated predictors of progression free survival in anal canal cancer.
Sara E Beltrán Ponce, Beth A Erickson, William A Hall, Meena Bedi, Michael J Martens, Malika Siker, James Thomas, Ben George, Kirk Ludwig, Carrie Peterson, Timothy Rid...> ;Journal of Gastrointestinal Oncology. 2022 Feb 1
50 citations
Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency.
Anirban Das, Sumedha Sudhaman, Daniel Morgenstern, Ailish Coblentz, Jiil Chung, Simone C Stone, Noor Alsafwani, Zhihui Amy Liu, Ola Abu Al Karsaneh, Shirin Soleimani, ...> ;Nature Medicine. 2022 Jan 1
2 citations
Updates and new directions in the use of radiation therapy for the treatment of pancreatic adenocarcinoma: dose, sensitization, and novel technology.
William A. Hall, Mandana Kamgar, Beth Erickson, Sara Beltrán Ponce, Susan Tsai, Marja T. Nevalainen, Kathleen K. Christians, Ben George, Kulwinder S. Dua, Abdul H. Kha...> ;Cancer Metastasis Reviews. 2021 Oct 6
Precision Medicine and Pancreatic Cancer.
Ben George> ;Surgical Oncology Clinics of North America. 2021 Oct 1
44 citations
Telemedicine Adoption during the COVID-19 Pandemic: Gaps and Inequalities.
Jake Luo, Ling Tong, Bradley H. Crotty, Melek Somai, Bradley K. Taylor, Kristen Osinski, Ben George> ;Applied Clinical Informatics. 2021 Aug 1
140 citations
Pertuzumab and trastuzumab for HER2-positive, metastatic biliary tract cancer (MyPathway): a multicentre, open-label, phase 2a, multiple basket study
Milind Javle, Mitesh J. Borad, Nilofer S. Azad, Razelle Kurzrock, Ghassan K. Abou-Alfa, Ben George, John D. Hainsworth, Funda Meric-Bernstam, Charles Swanton, Christop...> ;The Lancet. Oncology. 2021 Sep 1
1 citations
Evolution of Systemic Therapy in Metastatic Pancreatic Ductal Adenocarcinoma.
Mandana Kamgar, Sakti Chakrabarti, Aditya Shreenivas, Ben George> ;Surgical Oncology Clinics of North America. 2021 Jul 22
Germline evaluation of patients undergoing tumor genomic profiling: An academic cancer center's experience with implementing a germline review protocol.
Samantha Stachowiak, Amanda Jacquart, Michael T. Zimmermann, Ben George, Huaying Dong, Jennifer L. Geurts> ;Journal of Genetic Counseling. 2021 Mar 22
3 citations
Cost-effectiveness analysis of universal germline testing for patients with pancreatic cancer.
Ashley N. Krepline, Jennifer L. Geurts, Ben George, Mandana Kamgar, Srivats Madhavan, Beth Erickson, William A. Hall, Michael O. Griffin, Douglas B. Evans, Susan Tsai,...> ;Surgery. 2021 Mar 1
6 citations
The Association of Real-World CA 19-9 Level Monitoring Patterns and Clinical Outcomes Among Patients With Metastatic Pancreatic Ductal Adenocarcinoma.
Ben George, Matthew Kent, Andy Surinach, Neil Lamarre, Paul Cockrum> ;Frontiers in Oncology. 2021 Jan 1
35 citations
DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells.
Jiil Chung, Yosef E. Maruvka, Sumedha Sudhaman, Jacalyn Kelly, Nicholas J. Haradhvala, Vanessa Bianchi, Melissa Edwards, Victoria J. Forster, Nuno Miguel Nunes, Meliss...> ;Cancer Discovery. 2021 May 1
35 citations
Adjuvant therapy rates and overall survival in patients with localized pancreatic cancer from high Area Deprivation Index neighborhoods.
Javier Mora, Ashley N. Krepline, Mohammed Aldakkak, Kathleen K. Christians, Ben George, William A. Hall, Beth Erickson, Naveen M. Kulkarni, Douglas B. Evans, Susan Tsai> ;American Journal of Surgery. 2021 Jul 1
15 citations
Bronchoalveolar lavage-based COVID-19 testing in patients with cancer.
Muhammad Bilal Abid, Saurabh Chhabra, Blake W. Buchan, Mary Beth Graham, Sameem Abedin, Bicky Thapa, Anita D'Souza, Ben George, Mehdi Hamadani> ;Hematology/oncology and Stem Cell Therapy. 2021 Mar 1
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Lectures

Analysis of hematologic adverse events (HeAEs) in trifluridine/tipiracil (FTD/TPI)-treated patients (pts) with or without renal/hepatic impairment (RI/HI): Pooled safe...
ASCO Gastrointestinal Cancers Symposium - San Francisco, CA - 1/25/2020

Press Mentions

BostonGene, Medical College of Wisconsin Partner on Pancreatic Cancer Biomarker ResearchApril 27th, 2021
Schedule at A GlanceJune 8th, 2015
Understanding Precision MedicineAugust 25th, 2023